The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
Raman and CARS microspectroscopy of cells and tissues
Abstract
Raman spectroscopy has been recognized to be a powerful tool to study cells and tissues because the method provides molecular information without external markers such as stains or radioactive labels. To overcome the disadvantage of low signal intensities from most biomolecules, enhancement effects are utilized. A non-linear variant of Raman spectroscopy called coherent anti-Stokes Raman spectroscopy (CARS) belongs to the most promising techniques because it combines signal enhancement due to the coherent nature of the process with further advantages such as directional emission, narrow spectral bandwidth and no disturbing interference with autofluorescence. This review describes briefly the principles of the methods and summarizes applications to cells and tissues that are expected to gain significance in the future such as the combination with imaging approaches, microscopy, optical traps and fiber-optic probes.
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Cites
International Journal of Oncology
(2026) · International Journal of Oncology · doi:10.3892/ijo · Cited by 2,331
Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy
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Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy
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Studying single living cells and chromosomes by confocal Raman microspectroscopy
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Near‐infrared Raman spectroscopy for optical diagnosis of lung cancer
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Micro-Raman Spectroscopy Detects Individual Neoplastic and Normal Hematopoietic Cells
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Using Raman spectroscopy to characterize biological materials
Butler, H. J., Ashton, L., Bird, B., Cinque, G., Curtis, K., Dorney, J., Esmonde-White, K., Fullwood, N. J., Gardner, B., Martin-Hirsch, P. L., et al. (2016) · Nature Protocols · doi:10.1038/nprot.2016.036 · Cited by 1,309
How to pre-process Raman spectra for reliable and stable models?
Bocklitz, T., Walter, A., Hartmann, K., Rösch, P., & Popp, J. (2011) · Analytica Chimica Acta · doi:10.1016/j.aca.2011.06.043 · Cited by 282
Self-citationLabel‐Free Live‐Cell Imaging of Nucleic Acids Using Stimulated Raman Scattering Microscopy
Zhang, X., Roeffaers, M. B. J., Basu, S., Daniele, J. R., Fu, D., Freudiger, C. W., Holtom, G. R., & Xie, X. S. (2012) · ChemPhysChem · doi:10.1002/cphc.201100890 · Cited by 171
In Vivo Live Cell Imaging for the Quantitative Monitoring of Lipids by Using Raman Microspectroscopy
Hosokawa, M., Ando, M., Mukai, S., Osada, K., Yoshino, T., Hamaguchi, H.-O., & Tanaka, T. (2014) · Analytical Chemistry · doi:10.1021/ac501591d · Cited by 47
Chernenko, T., Buyukozturk, F., Miljkovic, M., Carrier, R., Diem, M., & Amiji, M. (2013) · Drug Delivery and Translational Research · doi:10.1007/s13346-013-0178-3 · Cited by 24
Metadata
- Authors
- Krafft, C., Dietzek, B., & Popp, J.
- Venue
- The Analyst
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2009
- Volume
- 134
- Issue
- 6
- Pages
- 1046
- ISSN
- 0003-2654 (ISSN-L)
- 1364-5528
- OpenAlex
- W1891609328
- Cited by
- 271
- References
- 118
- FWCI
- 15.94
- Type
- journal article
- Language
- en
- Open access
- closed
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