The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Modern Humans Did Not Admix with Neanderthals during Their Range Expansion into Europe
Open accessAbstract
The process by which the Neanderthals were replaced by modern humans between 42,000 and 30,000 before present is still intriguing. Although no Neanderthal mitochondrial DNA (mtDNA) lineage is found to date among several thousands of Europeans and in seven early modern Europeans, interbreeding rates as high as 25% could not be excluded between the two subspecies. In this study, we introduce a realistic model of the range expansion of early modern humans into Europe, and of their competition and potential admixture with local Neanderthals. Under this scenario, which explicitly models the dynamics of Neanderthals' replacement, we estimate that maximum interbreeding rates between the two populations should have been smaller than 0.1%. We indeed show that the absence of Neanderthal mtDNA sequences in Europe is compatible with at most 120 admixture events between the two populations despite a likely cohabitation time of more than 12,000 y. This extremely low number strongly suggests an almost complete sterility between Neanderthal females and modern human males, implying that the two populations were probably distinct biological species.
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Citations
Cites
Modern human origins: progress and prospects
Stringer, C. (2002) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.2001.1057 · Cited by 534 · cited 2×
“It thus gives more credit to the RAO hypothesis (Excoffier 2002; Stringer 2002), since some very divergent H. erectus mitochondrial sequences should have also been observed if interbreeding had occurred during the colonization of Eurasia by modern humans from Africa.”
BackgroundY genetic data support the Neolithic demic diffusion model
Chikhi, L., Nichols, R. A., Barbujani, G., & Beaumont, M. A. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162158799 · Cited by 327
Surprisingly rapid growth in Neanderthals
Ramirez Rozzi, F. V., & Bermudez de Castro, J. M. (2004) · Nature · doi:10.1038/nature02428 · Cited by 289
Population kinetics in the Upper Palaeolithic in Western Europe
Bocquet-Appel, J.-P., & Demars, P.-Y. (2000) · Journal of Archaeological Science · doi:10.1006/jasc.1999.0471 · Cited by 126
The Neanderthal taxonomic position: models of intra- and inter-specific craniofacial variation
Harvati, K. (2003) · Journal of Human Evolution · doi:10.1016/s0047-2484(02)00208-7 · Cited by 123
Detecting Ancient Admixture in Humans Using Sequence Polymorphism Data
Wall, J. D. (2000) · Genetics · doi:10.1093/genetics/154.3.1271 · Cited by 116
Indo‐European origins: A computer‐simulation test of five hypotheses
Barbujani, G., Sokal, R. R., & Oden, N. L. (1995) · American Journal of Physical Anthropology · doi:10.1002/ajpa.1330960202 · Cited by 104
Cited by
A draft sequence of the Neandertal genome
Green, R. E., Krause, J., Briggs, A. W., Maricic, T., Stenzel, U., Kircher, M., Patterson, N., Li, H., Zhai, W., Fritz, M. H.-Y., et al. (2010) · Science · doi:10.1126/science.1188021 · Cited by 4,318
Ancient DNA and the rewriting of human history: be sparing with Occam’s razor
Haber, M., Mezzavilla, M., Xue, Y., & Tyler-Smith, C. (2016) · Genome Biology · doi:10.1186/s13059-015-0866-z · Cited by 1,924
Testing for ancient admixture between closely related populations
Durand, E. Y., Patterson, N., Reich, D., & Slatkin, M. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msr048 · Cited by 1,375
THE HIDDEN SIDE OF INVASIONS: MASSIVE INTROGRESSION BY LOCAL GENES
Currat, M., Ruedi, M., Petit, R. J., & Excoffier, L. (2008) · Evolution · doi:10.1111/j.1558-5646.2008.00413.x · Cited by 816
Self-citationAnalysis of one million base pairs of Neanderthal DNA
Green, R. E., Krause, J., Ptak, S. E., Briggs, A. W., Ronan, M. T., Simons, J. F., Du, L., Egholm, M., Rothberg, J. M., Paunovic, M., et al. (2006) · Nature · doi:10.1038/nature05336 · Cited by 760
Metadata
- Authors
- Currat, M., & Excoffier, L.
- Venue
- PLoS Biology
- Publisher
- Public Library of Science (PLoS)
- Published
- 2004-11-30
- Volume
- 2
- Issue
- 12
- Pages
- e421
- ISSN
- 1544-9173 (ISSN-L)
- 1545-7885
- OpenAlex
- W1974329144
- Cited by
- 376
- References
- 7
- FWCI
- 194.17
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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