The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
High-Throughput In Vivo Analysis of Gene Expression in Caenorhabditis elegans
Open accessAbstract
Using DNA sequences 5' to open reading frames, we have constructed green fluorescent protein (GFP) fusions and generated spatial and temporal tissue expression profiles for 1,886 specific genes in the nematode Caenorhabditis elegans. This effort encompasses about 10% of all genes identified in this organism. GFP-expressing wild-type animals were analyzed at each stage of development from embryo to adult. We have identified 5' DNA regions regulating expression at all developmental stages and in 38 different cell and tissue types in this organism. Among the regulatory regions identified are sequences that regulate expression in all cells, in specific tissues, in combinations of tissues, and in single cells. Most of the genes we have examined in C. elegans have human orthologs. All the images and expression pattern data generated by this project are available at WormAtlas (http://gfpweb.aecom.yu.edu/index) and through WormBase (http://www.wormbase.org).
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Cites
The structure of the nervous system of the nematode Caenorhabditis elegans
White, J. G., Southgate, E., Thomson, J. N., & Brenner, S. (1986) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences · doi:10.1098/rstb.1986.0056 · Cited by 5,589
Genome-wide atlas of gene expression in the adult mouse brain
Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., et al. (2007) · Nature · doi:10.1038/nature05453 · Cited by 5,572
The embryonic cell lineage of the nematode Caenorhabditis elegans
Sulston, J. E., Schierenberg, E., White, J. G., & Thomson, J. N. (1983) · Developmental Biology · doi:10.1016/0012-1606(83)90201-4 · Cited by 4,199
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
Gong, S., Zheng, C., Doughty, M. L., Losos, K., Didkovsky, N., Schambra, U. B., Nowak, N. J., Joyner, A., Leblanc, G., Hatten, M. E., et al. (2003) · Nature · doi:10.1038/nature02033 · Cited by 2,108
Cited by
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans aging
Ben-Zvi, A., Miller, E. A., & Morimoto, R. I. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902882106 · Cited by 649
Insulin/insulin-like growth factor signaling in C. elegans
Murphy, C. T. (2013) · WormBook · doi:10.1895/wormbook.1.164.1 · Cited by 532
3′ UTRs Are the Primary Regulators of Gene Expression in the C. elegans Germline
Merritt, C., Rasoloson, D., Ko, D., & Seydoux, G. (2008) · Current Biology · doi:10.1016/j.cub.2008.08.013 · Cited by 379
The Multilayer Connectome of Caenorhabditis elegans
Bentley, B., Branicky, R., Barnes, C. L., Chew, Y. L., Yemini, E., Bullmore, E. T., Vértes, P. E., & Schafer, W. R. (2016) · PLOS Computational Biology · doi:10.1371/journal.pcbi.1005283 · Cited by 269
Expanding the Genetic Code of an Animal
Greiss, S., & Chin, J. W. (2011) · Journal of the American Chemical Society · doi:10.1021/ja2054034 · Cited by 254
Metadata
- Authors
- Hunt-Newbury, R., Viveiros, R., Johnsen, R., Mah, A., Anastas, D., Fang, L., Halfnight, E., Lee, D., Lin, J., Lorch, A., McKay, S., Okada, H. M., Pan, J., Schulz, A. K., Tu, D., Wong, K., Zhao, Z., Alexeyenko, A., Burglin, T., Sonnhammer, E., Schnabel, R., Jones, S. J., Marra, M. A., Baillie, D. L., & Moerman, D. G.
- Venue
- PLoS Biology
- Publisher
- Public Library of Science (PLoS)
- Published
- 2007-09-11
- Volume
- 5
- Issue
- 9
- Pages
- e237
- ISSN
- 1544-9173 (ISSN-L)
- 1545-7885
- OpenAlex
- W2087072206
- Cited by
- 376
- References
- 4
- FWCI
- 9.58
- Type
- journal article
- Language
- en
- Open access
- gold
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- Hunt-Newbury, R., Viveiros, R., Johnsen, R., Mah, A., Anastas, D., Fang, L., Halfnight, E., Lee, D., Lin, J., Lorch, A., McKay, S., Okada, H. M., Pan, J., Schulz, A. K., Tu, D., Wong, K., Zhao, Z., Alexeyenko, A., Burglin, T., . . . Moerman, D. G. (2007). High-Throughput In Vivo Analysis of Gene Expression in Caenorhabditis elegans. PLoS Biology. https://doi.org/10.1371/journal.pbio.0050237
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
