Two Chromatin Remodeling Activities Cooperate during Activation of Hormone Responsive Promoters

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

Cox, J., & Mann, M. (2008) · Nature Biotechnology · doi:10.1038/nbt.1511 · Cited by 14,855 · see citing works

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

Dignam, J. D., Lebovitz, R. M., & Roeder, R. G. (1983) · Nucleic Acids Research · doi:10.1093/nar/11.5.1475 · Cited by 11,262 · see citing works

Crystal structure of the nucleosome core particle at 2.8 Å resolution

Luger, K., Mäder, A. W., Richmond, R. K., Sargent, D. F., & Richmond, T. J. (1997) · Nature · doi:10.1038/38444 · Cited by 9,466 · see citing works

The language of covalent histone modifications

Strahl, B. D., & Allis, C. D. (2000) · Nature · doi:10.1038/47412 · Cited by 8,679 · see citing works

Stop and Go Extraction Tips for Matrix-Assisted Laser Desorption/Ionization, Nanoelectrospray, and LC/MS Sample Pretreatment in Proteomics

Rappsilber, J., Ishihama, Y., & Mann, M. (2002) · Analytical Chemistry · doi:10.1021/ac026117i · Cited by 2,589 · see citing works

Histone Acetyltransferases

Dent, S., Denu, J. M., & Allis, C. D. (2001) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.70.1.81 · Cited by 1,844 · see citing works

Steroid hormone receptors: Many Actors in search of a plot

Beato, M., Herrlich, P. A., & Schütz, G. (1995) · Cell · doi:10.1016/0092-8674(95)90201-5 · Cited by 1,806 · see citing works

Parts per Million Mass Accuracy on an Orbitrap Mass Spectrometer via Lock Mass Injection into a C-trap

Olsen, J. V., de Godoy, L. M. F., Li, G., Maček, B., Mortensen, P., Pesch, R., Makarov, A., Lange, O., Horning, S. R., & Mann, M. (2005) · Molecular & Cellular Proteomics · doi:10.1074/mcp.t500030-mcp200 · Cited by 1,513 · see citing works

Cooperation between Complexes that Regulate Chromatin Structure and Transcription

Narlikar, G. J., Fan, H.-Y., & Kingston, R. E. (2002) · Cell · doi:10.1016/s0092-8674(02)00654-2 · Cited by 1,486 · see citing works

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

Yang, X., Ogryzko, V. V., Nishikawa, J., Howard, B. H., & Nakatani, Y. (1996) · Nature · doi:10.1038/382319a0 · Cited by 1,473 · see citing works

Signaling to Chromatin through Histone Modifications

Cheung, P., Allis, C. D., & Sassone-Corsi, P. (2000) · Cell · doi:10.1016/s0092-8674(00)00118-5 · Cited by 989 · see citing works

Selective Anchoring of TFIID to Nucleosomes by Trimethylation of Histone H3 Lysine 4

Vermeulen, M., Mulder, K. W., Denissov, S., Pijnappel, W. W. M. P., van Schaik, F. M. A., Varier, R. A., Baltissen, M. P. A., Stunnenberg, H. G., Mann, M., & Timmers, H. T. M. (2007) · Cell · doi:10.1016/j.cell.2007.08.016 · Cited by 883 · see citing works

Diversity and specialization of mammalian SWI/SNF complexes.Preprint

Wang, W., Xue, Y., Zhou, S., Kuo, A. C., Cairns, B. R., & Crabtree, G. R. (1996) · Genes & Development · doi:10.1101/gad.10.17.2117 · Cited by 707 · see citing works

Formation of the Androgen Receptor Transcription Complex

Shang, Y., Myers, M., & Brown, M. A. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00471-9 · Cited by 673 · see citing works

Deciphering the Transcriptional Histone Acetylation Code for a Human Gene

Agalioti, T., Chen, G., & Thanos, D. (2002) · Cell · doi:10.1016/s0092-8674(02)01077-2 · Cited by 639 · see citing works

Transcription Factor-Specific Requirements for Coactivators and Their Acetyltransferase Functions

Korzus, E., Torchia, J., Rose, D. W., Xu, L., Kurokawa, R., McInerney, E. M., Mullen, T.-M., Glass, C. K., & Rosenfeld, M. G. (1998) · Science · doi:10.1126/science.279.5351.703 · Cited by 632 · see citing works

Analysis and validation of proteomic data generated by tandem mass spectrometry

Nesvizhskii, A. I., Vitek, O., & Aebersold, R. H. (2007) · Nature Methods · doi:10.1038/nmeth1088 · Cited by 629 · see citing works

Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross‐talk with estrogen receptor

Migliaccio, A., Piccolo, D., Castoria, G., Domenico, M. D., Bilancio, A., Lombardi, M., Gong, W., Beato, M., & Auricchio, F. (1998) · The EMBO Journal · doi:10.1093/emboj/17.7.2008 · Cited by 627 · see citing works

Characterization of the yeast SWI1, SWI2, and SWI3 genes, which encode a global activator of transcription

Peterson, C. L., & Herskowitz, I. (1992) · Cell · doi:10.1016/0092-8674(92)90192-f · Cited by 601 · see citing works

Sequence‐specific positioning of nucleosomes over the steroid‐inducible MMTV promoter.

Richard-Foy, H., & Hager, G. L. (1987) · The EMBO Journal · doi:10.1002/j.1460-2075.1987.tb02507.x · Cited by 594 · see citing works

A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor.

Muchardt, C., & Yaniv, M. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06112.x · Cited by 588 · see citing works

The diverse functions of histone acetyltransferase complexes

Carrozza, M. J., Utley, R. T., Workman, J. L., & Côté, J. (2003) · Trends in Genetics · doi:10.1016/s0168-9525(03)00115-x · Cited by 576 · see citing works

Roles of the NFI/CTF gene family in transcription and development

Gronostajski, R. M. (2000) · Gene · doi:10.1016/s0378-1119(00)00140-2 · Cited by 545 · see citing works

Function and Selectivity of Bromodomains in Anchoring Chromatin-Modifying Complexes to Promoter Nucleosomes

Hassan, A. H., Prochasson, P., Neely, K. E., Galasinski, S. C., Chandy, M., Carrozza, M. J., & Workman, J. L. (2002) · Cell · doi:10.1016/s0092-8674(02)01005-x · Cited by 533 · see citing works

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

Fryer, C. J., & Archer, T. K. (1998) · Nature · doi:10.1038/30032 · Cited by 511 · see citing works

Chromatin remodelling at promoters suppresses antisense transcription

Whitehouse, I., Rando, O. J., Delrow, J., & Tsukiyama, T. (2007) · Nature · doi:10.1038/nature06391 · Cited by 456 · see citing works

Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)

Reyes, J. C., Barra, J., Muchardt, C., Camus, A., Babinet, C., & Yaniv, M. (1998) · The EMBO Journal · doi:10.1093/emboj/17.23.6979 · Cited by 433 · see citing works

Nucleosome positioning modulates accessibility of regulatory proteins to the mouse mammary tumor virus promoter

Piña, B., Brüggemeier, U., & Beato, M. (1990) · Cell · doi:10.1016/0092-8674(90)90087-u · Cited by 423 · see citing works

Overlapping but Distinct Patterns of Histone Acetylation by the Human Coactivators p300 and PCAF within Nucleosomal Substrates

Schiltz, R. L., Mizzen, C. A., Vassilev, A. P., Cook, R. G., Allis, C. D., & Nakatani, Y. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.3.1189 · Cited by 416 · see citing works

The histone acetylase PCAF is a nuclear receptor coactivatorPreprint

Blanco, J. C. G., Minucci, S., Lü, J., Yang, X., Walker, K. K., Chen, H., Evans, R. M., Nakatani, Y., & Ozato, K. (1998) · Genes & Development · doi:10.1101/gad.12.11.1638 · Cited by 388 · see citing works

Histone Acetyltransferase Complexes Stabilize SWI/SNF Binding to Promoter Nucleosomes

Hassan, A. H., Neely, K. E., & Workman, J. L. (2001) · Cell · doi:10.1016/s0092-8674(01)00279-3 · Cited by 365 · see citing works

Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes

Mohrmann, L., & Verrijzer, C. P. (2004) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/j.bbaexp.2004.10.005 · Cited by 346 · see citing works

Hormone induces binding of receptors and transcription factors to a rearranged nucleosome on the MMTV promoter in vivo.

Truss, M., Bartsch, J. W., Schelbert, A., Haché, R. J. G., & Beato, M. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07163.x · Cited by 307 · see citing works

A Novel Proteomic Screen for Peptide-Protein Interactions

Schulze, W. X., & Mann, M. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m309909200 · Cited by 298 · see citing works

A Specificity and Targeting Subunit of a Human SWI/SNF Family-Related Chromatin-Remodeling Complex

Nie, Z., Xue, Y., Yang, D., Zhou, S., Deroo, B. J., Archer, T., & Wang, W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.23.8879-8888.2000 · Cited by 298 · see citing works

Essential Functional Interactions of SAGA, a Saccharomyces cerevisiae Complex of Spt, Ada, and Gcn5 Proteins, With the Snf/Swi and Srb/Mediator Complexes

Roberts, S. M., & Winston, F. (1997) · Genetics · doi:10.1093/genetics/147.2.451 · Cited by 278 · see citing works

The human SWI/SNF-B chromatin-remodeling complex is related to yeast Rsc and localizes at kinetochores of mitotic chromosomes

Xue, Y., Canman, J. C., Lee, C.-S., Nie, Z., Yang, D., Moreno, G. T., Young, M. K., Salmon, E. D., & Wang, W. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.240208597 · Cited by 267 · see citing works

Histone modifications defining active genes persist after transcriptional and mitotic inactivation

Kouskouti, A., & Talianidis, I. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600516 · Cited by 263 · see citing works

PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genesPreprint

Yan, Z., Cui, K., Murray, D., Chen, L., Xue, Y., Gerstein, A. V., Parsons, R. E., Zhao, K., & Wang, W. (2005) · Genes & Development · doi:10.1101/gad.1323805 · Cited by 247 · see citing works

Targeting of SWI/SNF chromatin remodelling complexes to estrogen‐responsive genes

Belandia, B., Orford, R. L., Hurst, H. C., & Parker, M. G. (2002) · The EMBO Journal · doi:10.1093/emboj/cdf412 · Cited by 242 · see citing works

Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14

Kasten, M. M., Szerlong, H. J., Erdjument‐Bromage, H., Tempst, P., Werner, M., & Cairns, B. R. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600143 · Cited by 230 · see citing works

Two Functionally Distinct Forms of the RSC Nucleosome-Remodeling Complex, Containing Essential AT Hook, BAH, and Bromodomains

Cairns, B. R., Schlichter, A., Erdjument‐Bromage, H., Tempst, P., Kornberg, R. D., & Winston, F. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80382-2 · Cited by 225 · see citing works

Induction of Progesterone Target Genes Requires Activation of Erk and Msk Kinases and Phosphorylation of Histone H3

Vicent, G. P., Ballaré, C., Nacht, A. S., Clausell, J., Subtil-Rodríguez, A., Quiles, I., Jordan, A., & Beato, M. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.10.011 · Cited by 223 · see citing works

The transcriptionally-active MMTV promoter is depleted of histone H1

Bresnick, E. H., Bustin, M., Marsaud, V., Richard‐Foy, H., & Hager, G. L. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.2.273 · Cited by 215 · see citing works

Transcription in four dimensions: nuclear receptor‐directed initiation of gene expression

Métivier, R., Reid, G., & Gannon, F. (2006) · EMBO Reports · doi:10.1038/sj.embor.7400626 · Cited by 207 · see citing works

A role for cofactor–cofactor and cofactor–histone interactions in targeting p300, SWI/SNF and Mediator for transcription

Huang, Z.-Q., Li, J., Sachs, L. M., Cole, P. A., & Wong, J. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg219 · Cited by 203 · see citing works

What does ‘chromatin remodeling’ mean?

Aalfs, J. D., & Kingston, R. E. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01689-3 · Cited by 198 · see citing works

Histone H2A/H2B Dimer Exchange by ATP-Dependent Chromatin Remodeling Activities

Bruno, M., Flaus, A., Stockdale, C., Rencurel, C., Ferreira, H. C., & Owen‐Hughes, T. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00499-4 · Cited by 196 · see citing works

BAF57 Governs Androgen Receptor Action and Androgen-Dependent Proliferation through SWI/SNF

Link, K. A., Burd, C. J., Williams, E., Marshall, T. W., Rosson, G. B., Henry, E. C., Weissman, B. E., & Knudsen, K. E. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.6.2200-2215.2005 · Cited by 131 · see citing works

Two-Step Synergism between the Progesterone Receptor and the DNA-Binding Domain of Nuclear Factor 1 on MMTV Minichromosomes

Croce, L. D., Koop, R., Venditti, P., Westphal, H. M., Nightingale, K. P., Corona, D. F. V., Becker, P. B., & Beato, M. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80186-0 · Cited by 126 · see citing works

Solution Structure of Human Brg1 Bromodomain and Its Specific Binding to Acetylated Histone Tails,

Shen, W., Xu, C., Huang, W., Zhang, J., Carlson, J. E., Tu, X., Wu, J., & Shi, Y. (2007) · Biochemistry · doi:10.1021/bi0611208 · Cited by 126 · see citing works

Differential Requirement of SWI/SNF for Androgen Receptor Activity

Marshall, T. W., Link, K. A., Petre, C. E., & Knudsen, K. E. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304582200 · Cited by 121 · see citing works

Cyclin-Dependent Kinase Activity Is Required for Progesterone Receptor Function: Novel Role for Cyclin A/Cdk2 as a Progesterone Receptor Coactivator

Narayanan, R., Adigun, A. A., Edwards, D. P., & Weigel, N. L. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.25.1.264-277.2005 · Cited by 110 · see citing works

The SWI/SNF Family of ATP-Dependent Chromatin Remodelers: Similar Mechanisms for Diverse Functions

Wang, W. (2003) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-55747-7_6 · Cited by 110 · see citing works

ATP‐dependent nucleosome remodeling complexes: Enzymes tailored to deal with chromatin

Sif, S. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20005 · Cited by 107 · see citing works

The SWI/SNF Chromatin Remodeling Subunit BAF57 Is a Critical Regulator of Estrogen Receptor Function in Breast Cancer Cells

Garcia-Pedrero, J. M., Kiskinis, E., Parker, M. G., & Belandia, B. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m602561200 · Cited by 106 · see citing works

Histone H1 Phosphorylation by Cdk2 Selectively Modulates Mouse Mammary Tumor Virus Transcription through Chromatin Remodeling

Bhattacharjee, R. N., Banks, G. C., Trotter, K. W., Lee, H.-L., & Archer, T. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.16.5417-5425.2001 · Cited by 106 · see citing works

DNA Instructed Displacement of Histones H2A and H2B at an Inducible Promoter

Vicent, G. P., Nacht, A. S., Smith, C. L., Peterson, C. L., Dimitrov, S. I., & Beato, M. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.10.025 · Cited by 101 · see citing works

Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure.

Bartsch, J. W., Truss, M., Bode, J., & Beato, M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.20.10741 · Cited by 95 · see citing works

Swi3p controls SWI/SNF assembly and ATP-dependent H2A-H2B displacement

Yang, X., Zaurín, R., Beato, M., & Peterson, C. L. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1238 · Cited by 88 · see citing works

Histone H1 enhances synergistic activation of the MMTV promoter in chromatin

Koop, R., Croce, L. D., & Beato, M. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg052 · Cited by 72 · see citing works

Roles of Brahma and Brahma/SWI2-Related Gene 1 in Hypoxic Induction of the Erythropoietin Gene

Wang, F., Zhang, R., Beischlag, T. V., Muchardt, C., Yaniv, M., & Hankinson, O. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m409002200 · Cited by 71 · see citing works

Structural Ramification for Acetyl‐Lysine Recognition by the Bromodomain of Human BRG1 Protein, a Central ATPase of the SWI/SNF Remodeling Complex

Singh, M., Popowicz, G. M., Krajewski, M., & Holak, T. A. (2007) · ChemBioChem · doi:10.1002/cbic.200600562 · Cited by 64 · see citing works

Mapping DNA Target Sites of Chromatin Proteins In Vivo by Formaldehyde Crosslinking

Strutt, H. L., & Paro, R. (2003) · Humana Press eBooks · doi:10.1385/1-59259-681-9:455 · Cited by 62 · see citing works

Nuclear Factor 1 Is Required for Both Hormone-Dependent Chromatin Remodeling and Transcriptional Activation of the Mouse Mammary Tumor Virus Promoter

Hebbar, P. B., & Archer, T. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.3.887-898.2003 · Cited by 57 · see citing works

Chromatin-dependent Cooperativity between Site-specific Transcription Factors in Vivo

Hebbar, P. B., & Archer, T. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m610554200 · Cited by 53 · see citing works

Inhibition of MMTV transcription by HDAC inhibitors occurs independent of changes in chromatin remodeling and increased histone acetylation

Mulholland, N., Soeth, E., & Smith, C. L. (2003) · Oncogene · doi:10.1038/sj.onc.1206722 · Cited by 51 · see citing works

Chromatin Remodeling and Control of Cell Proliferation by Progestins via Cross Talk of Progesterone Receptor with the Estrogen Receptors and Kinase Signaling Pathways

Vicent, G. P., Ballaré, C., Zaurín, R., Saragüeta, P., & Beato, M. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1386.025 · Cited by 44 · see citing works

Maintenance of Integrated Proviral Gene Expression Requires Brm, a Catalytic Subunit of SWI/SNF Complex

Mizutani, T., Ito, T., Nishina, M., Yamamichi, N., Watanabe, A., & Iba, H. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m112421200 · Cited by 40 · see citing works

Assembly of MMTV promoter minichromosomes with positioned nucleosomes precludes NF1 access but not restriction enzyme cleavage

Venditti, P., Croce, L. D., Kauer, M., Beato, M., Blank, T. A., & Becker, P. B. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.16.3657 · Cited by 32 · see citing works

Transcriptional silencing of the mouse mammary tumor virus promoter through chromatin remodeling is concomitant with histone H1 phosphorylation and histone H3 hyperphosphorylation at M phase

Bhattacharjee, R. N., & Archer, T. (2006) · Virology · doi:10.1016/j.virol.2005.12.034 · Cited by 14 · see citing works

Transcription Factor NF 1 Expression in Involuting Mammary Gland

Kane, R., Finlay, D., Lamb, T., & Martin, F. (2005) · Kluwer Academic Publishers eBooks · doi:10.1007/0-306-46832-8_14 · Cited by 12 · see citing works

Transcription factors: from enhancer binding to developmental control

Spitz, F., & Furlong, E. E. M. (2012) · Nature Reviews Genetics · doi:10.1038/nrg3207 · Cited by 2,227 · see citing works

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

Bartke, T., Vermeulen, M., Xhemalce, B., Robson, S. C., Mann, M., & Kouzarides, T. (2010) · Cell · doi:10.1016/j.cell.2010.10.012 · Cited by 611 · see citing works

Vitamin A and retinoid signaling: genomic and nongenomic effects

Al Tanoury, Z., Piskunov, A., & Rochette-Egly, C. (2013) · Journal of Lipid Research · doi:10.1194/jlr.r030833 · Cited by 408 · see citing works

ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling

Wright, R. H. G., Lioutas, A., Dily, F. L., Soronellas, D., Pohl, A., Bonet, J., Nacht, A. S., Samino, S., Font-Mateu, J., Vicent, G. P., et al. (2016) · Science · doi:10.1126/science.aad9335 · Cited by 215 · see citing works

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis

Mishima, Y., Miyagi, S., Saraya, A., Negishi, M., Endoh, M., Endo, T. A., Toyoda, T., Shinga, J., Katsumoto, T., Chiba, T., et al. (2011) · Blood · doi:10.1182/blood-2011-01-331892 · Cited by 199 · see citing works

Genomic agonism and phenotypic antagonism between estrogen and progesterone receptors in breast cancer

Singhal, H., Greene, M. E., Tarulli, G. A., Zarnke, A. L., Bourgo, R. J., Lainé, M., Chang, Y.-F., Ma, S., Dembo, A. G., Raj, G. V., et al. (2016) · Science Advances · doi:10.1126/sciadv.1501924 · Cited by 150 · see citing works

Nucleosome-Driven Transcription Factor Binding and Gene Regulation

Ballaré, C., Castellano, G., Gaveglia, L., Althammer, S., González‐Vallinas, J., Eyras, E., Dily, F. L., Zaurín, R., Soronellas, D., Vicent, G. P., et al. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.10.019 · Cited by 140 · see citing works

Chromatin Loading of E2F-MLL Complex by Cancer-Associated Coregulator ANCCA via Reading a Specific Histone Mark

Revenko, A. S., Kalashnikova, E. V., Gemo, A. T., Zou, J. X., & Chen, H.-W. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.00484-10 · Cited by 130 · see citing works

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer

Guerrero-Martinez, J. A., & Reyes, J. C. (2018) · Scientific Reports · doi:10.1038/s41598-018-20217-3 · Cited by 121 · see citing works

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Page, B. D. G., Valerie, N. C. K., Wright, R. H. G., Wallner, O. A., Isaksson, R., Carter, M., Rudd, S. G., Loseva, O., Jemth, A., Almlöf, I., et al. (2018) · Nature Communications · doi:10.1038/s41467-017-02293-7 · Cited by 117 · see citing works

Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activationPreprint

Vicent, G. P., Nacht, A. S., Font-Mateu, J., Castellano, G., Gaveglia, L., Ballaré, C., & Beato, M. (2011) · Genes & Development · doi:10.1101/gad.621811 · Cited by 108 · see citing works

Unliganded progesterone receptor-mediated targeting of an RNA-containing repressive complex silences a subset of hormone-inducible genesPreprint

Vicent, G. P., Nacht, A. S., Zaurín, R., Font-Mateu, J., Soronellas, D., Dily, F. L., Reyes-Garau, D., & Beato, M. (2013) · Genes & Development · doi:10.1101/gad.215293.113 · Cited by 85 · see citing works

Phosphorylation and Recruitment of BAF60c in Chromatin Remodeling for Lipogenesis in Response to Insulin

Wang, Y., Wong, R. H.-F., Tang, T., Hudak, C. S. S., Yang, D., Duncan, R. E., & Sul, H. S. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.10.028 · Cited by 80 · see citing works

Non-Overlapping Progesterone Receptor Cistromes Contribute to Cell-Specific Transcriptional Outcomes

Clarke, C. L., & Graham, J. D. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035859 · Cited by 75 · see citing works

Arginine Citrullination at the C-Terminal Domain Controls RNA Polymerase II Transcription

Sharma, P., Lioutas, A., Fernández‐Fuentes, N., Quilez, J., Carbonell‐Caballero, J., Wright, R. H. G., Vona, C. D., Dily, F. L., Schüller, R., Eick, D., et al. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.10.016 · Cited by 66 · see citing works

H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing

Maksakova, I., Goyal, P., Bullwinkel, J., Brown, J. P., Bilenky, M., Mager, D., Singh, P. B., & Lorincz, M. (2011) · Epigenetics & Chromatin · doi:10.1186/1756-8935-4-12 · Cited by 52 · see citing works

Minireview: Role of Kinases and Chromatin Remodeling in Progesterone Signaling to Chromatin

Vicent, G. P., Nacht, A. S., Zaurín, R., Ballaré, C., Clausell, J., & Beato, M. (2010) · Molecular Endocrinology · doi:10.1210/me.2010-0027 · Cited by 55 · see citing works

The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cells

Ogara, M. F., Rodríguez‐Seguí, S. A., Marini, M., Nacht, A. S., Stortz, M., Levi, V., Presman, D. M., Vicent, G. P., & Pecci, A. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz857 · Cited by 45 · see citing works

The Chromatin Remodeler CHD8 Is Required for Activation of Progesterone Receptor-Dependent Enhancers

Ceballos-Chávez, M., Subtil‐Rodríguez, A., Γιαννοπούλου, Ε., Soronellas, D., Vázquez-Chávez, E., Vicent, G. P., Elemento, O., Beato, M., & Reyes, J. C. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005174 · Cited by 41 · see citing works

Control of nuclear receptor function by local chromatin structure

Wiench, M., Miranda, T. B., & Hager, G. L. (2011) · FEBS Journal · doi:10.1111/j.1742-4658.2011.08126.x · Cited by 42 · see citing works

Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development

Mishima, Y., Wang, C., Miyagi, S., Saraya, A., Hosokawa, H., Mochizuki‐Kashio, M., Nakajima‐Takagi, Y., Koide, S., Negishi, M., Sashida, G., et al. (2014) · Nature Communications · doi:10.1038/ncomms6872 · Cited by 42 · see citing works

Hormone‐induced repression of genes requires BRG1‐mediated H1.2 deposition at target promoters

Nacht, A. S., Pohl, A., Zaurín, R., Soronellas, D., Quilez, J., Sharma, P., Wright, R. H. G., Beato, M., & Vicent, G. P. (2016) · The EMBO Journal · doi:10.15252/embj.201593260 · Cited by 43 · see citing works

Epigenetic fingerprint in endometrial carcinogenesis: The hypothesis of a uterine field cancerization

Domenico, M. D., Santoro, A., Ricciardi, C., Iaccarino, M., Iaccarino, S., Freda, M., Feola, A., Sanguedolce, F., Losito, S., Pasquali, D., et al. (2011) · Cancer Biology & Therapy · doi:10.4161/cbt.12.5.15963 · Cited by 41 · see citing works

Impact of chromatin structure and dynamics on PR signaling. The initial steps in hormonal gene regulation

Beato, M., & Vicent, G. P. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.004 · Cited by 33 · see citing works

Decoding GnRH neurohormone pulse frequency by convergent signalling modules

Tsaneva-Atanasova, K., Mina, P., Caunt, C. J., Armstrong, S. P., & McArdle, C. A. (2012) · Journal of The Royal Society Interface · doi:10.1098/rsif.2011.0215 · Cited by 31 · see citing works

Activation of mitogen- and stress-activated kinase 1 is required for proliferation of breast cancer cells in response to estrogens or progestins

Reyes-Garau, D., Ballaré, C., Castellano, G., Soronellas, D., Bagó, J. R., Blanco, J., & Beato, M. (2013) · Oncogene · doi:10.1038/onc.2013.95 · Cited by 31 · see citing works

Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and inducesSNAI2expressionviaBrg1 chromatin remodeling protein

Warsito, D., Lin, Y., Gnirck, A.-C., Sehat, B., & Larsson, O. (2016) · Oncotarget · doi:10.18632/oncotarget.9785 · Cited by 29 · see citing works

Erk signaling and chromatin remodeling in MMTV promoter activation by progestins

Vicent, G. P., Zaurín, R., Ballaré, C., Nacht, A. S., & Beato, M. (2009) · Nuclear Receptor Signaling · doi:10.1621/nrs.07008 · Cited by 29 · see citing works

Targeting HSPA1A in ARID2-deficient lung adenocarcinoma

Wang, X., Wang, Y., Fang, Z., Wang, H., Zhang, J., Zhang, L., Huang, H., Jiang, Z., Jin, Y., Han, X., et al. (2021) · National Science Review · doi:10.1093/nsr/nwab014 · Cited by 28 · see citing works

Nuclear Factor 1 Synergizes with Progesterone Receptor on the Mouse Mammary Tumor Virus Promoter Wrapped around a Histone H3/H4 Tetramer by Facilitating Access to the Central Hormone-responsive Elements

Vicent, G. P., Zaurín, R., Nacht, A. S., Font-Mateu, J., Dily, F. L., & Beato, M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.060848 · Cited by 26 · see citing works

C/EBPα mediates the growth inhibitory effect of progestins on breast cancer cells

Nacht, A. S., Ferrari, R., Zaurín, R., Scabia, V., Carbonell‐Caballero, J., Dily, F. L., Quilez, J., Leopoldi, A., Brisken, C., Beato, M., et al. (2019) · The EMBO Journal · doi:10.15252/embj.2018101426 · Cited by 23 · see citing works

SWI/SNF-type complexes–transcription factor interplay: a key regulatory interaction

Maassen, A., Steciuk, J., Wilga, M., Szurmak, J., Garbicz, D., Sarnowska, E. A., & Sarnowski, T. J. (2025) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-025-00704-y · Cited by 23 · see citing works

Impact of chromatin structure on PR signaling: Transition from local to global analysis

Grøntved, L., & Hager, G. L. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.006 · Cited by 22 · see citing works

A new role for an old player

Beato, M., & Vicent, G. P. (2013) · Transcription · doi:10.4161/trns.25777 · Cited by 19 · see citing works

Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation

Bertucci, P. Y., Nacht, A. S., Alló, M., Rocha-Viegas, L., Ballaré, C., Soronellas, D., Castellano, G., Zaurín, R., Kornblihtt, A. R., Beato, M., et al. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt327 · Cited by 17 · see citing works

Linker histones in hormonal gene regulation

Vicent, G. P., Wright, R. H. G., & Beato, M. (2015) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2015.10.016 · Cited by 17 · see citing works

More help than hindrance

Ballaré, C., Zaurín, R., Vicent, G. P., & Beato, M. (2013) · Nucleus · doi:10.4161/nucl.25108 · Cited by 16 · see citing works

90 YEARS OF PROGESTERONE: Molecular mechanisms of progesterone receptor action on the breast cancer genome

Beato, M., Wright, R. H. G., & Dily, F. L. (2020) · Journal of Molecular Endocrinology · doi:10.1530/jme-19-0266 · Cited by 16 · see citing works

Targeting the BAF complex in advanced prostate cancer

Hartley, A., Leung, H. Y., & Ahmad, I. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1821644 · Cited by 12 · see citing works

Ikaros changes the face of NuRD remodeling

Oestreich, K. J., & Weinmann, A. S. (2011) · Nature Immunology · doi:10.1038/ni.2191 · Cited by 11 · see citing works

Gonadal Steroid Action

McKenna, N. J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00009-0 · Cited by 11 · see citing works

MSK1 and Nuclear Receptors Signaling

Piskunov, A., & Rochette‐Egly, C. (2013) · Cited by 9 · see citing works

Evolutionary analysis reveals the role of a non-catalytic domain of peptidyl arginine deiminase 2 in transcriptional regulation

(2024) · doi:10.1016/j.isci.2024.109584 · Cited by 6 · see citing works

Steroid hormone receptors silence genes by a chromatin-targeted mechanism similar to those used for gene activation

Nacht, A. S., Beato, M., & Vicent, G. P. (2016) · Transcription · doi:10.1080/21541264.2016.1242456 · Cited by 4 · see citing works

Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone

Wright, R. H. G., Vastolo, V., Quilez, J., Carbonell‐Caballero, J., & Beato, M. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.888802 · Cited by 3 · see citing works

ADP-ribose derived Nuclear ATP is Required for Chromatin Remodeling and Hormonal Gene Regulation (97 charact)Preprint

Wright, R. H. G., Dily, F. L., Soronellas, D., Pohl, A., Bonet, J., Nacht, A. S., Vicent, G. P., Wierer, M., Oliva, B., & Beato, M. (2014) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/006593 · Cited by 2 · see citing works

Signalling Network of Breast Cancer Cells in Response to ProgesteronePreprint

Wright, R. H. G., Vastolo, V., Quilez, J., Carbonell‐Caballero, J., & Beato, M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.03.366401 · Cited by 2 · see citing works

Signaling to Chromatin Minireview: Role of Kinases and Chromatin Remodeling in Progesterone

Vicent, G. P., Nacht, A. S., Zaurín, R., Ballaré, C., Clausell, J., & Beato, M. (2010) · Cited by 1 · see citing works

Arginine citrullination at the C-terminal domain controls RNA polymerase II transcriptionPreprint

Sharma, P., Lioutas, A., Fernandez-Fuentes, N., Quilez, J., Carbonell‐Caballero, J., Wright, R. H. G., Vona, C. D., Dily, F. L., Schüller, R., Eick, D., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/216143 · Cited by 1 · see citing works

Pervasive chromatin remodeling at X-inactivation escape genes in schizophrenic malesPreprint

Hassan, H., & Hegyi, H. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/300624 · Cited by 1 · see citing works

Global Analysis of the Signalling Network of Breast Cancer Cells in Response to Progesterone.Preprint

Wright, R. H. G., Vastolo, V., Quilez, J., & Beato, M. (2021) · Research Square · doi:10.21203/rs.3.rs-958950/v1

Global Analysis of The Signalling Network of Breast Cancer Cells In Response To Progesterone.Preprint

Wright, R. H. G., Vastolo, V., Quilez, J., Carbonell‐Caballero, J., & Beato, M. (2021) · Research Square · doi:10.21203/rs.3.rs-958950/v2

ChIP happens: from biochemical origins to the modern omics toolbox for understanding steroid hormone receptors

Grimes, T. F., Pope, J., Stenning, J., Smith, T. E., Kent, D. G., Baker, S. C., Brackenbury, W. J., Willems, L. I., & Holding, A. N. (2026) · Biochemical Journal · doi:10.1042/bcj20253216

Network pharmacology of berberine in the treatment of breast cancer

Chen, Y.-T., & Zhang, X. (2024) · Integrate Medicine · doi:10.61958/imtd2483

Nucleic sexual hormone receptor signaling pathways in breast cancer: function regulation, crosstalk, and therapeutic implications

Zeng, K., Wang, A.-Q., Sun, H.-M., Wang, C.-Y., Wang, S.-L., Zou, R.-L., Yang, D.-J., Bai, Y., Wang, M.-L., Xu, Y.-Y., et al. (2026) · npj Precision Oncology · doi:10.1038/s41698-026-01568-x

Minireview: Role of Kinases and Chromatin Remodeling in Progesterone Signaling to Chromatin

Vicent, G. P., Nacht, A. S., Zaurín, R., Ballaré, C., Clausell, J., & Beato, M. (2010) · Molecular Endocrinology · doi:10.1210/me.2010-0027 · Cited by 55 · see citing works

Progesterone Signaling to Chromatin in Breast Cancer Cells. Two Initial Cycles of Remodeling

Vicent, G. P., Zaurín, R., Ballaré, C., Nacht, A. S., Wright, R. H. G., Dily, F. L., Castellano, G., Font-Mateu, J., & Beato, M. (2011) · Springer eBooks · doi:10.1007/978-1-4614-1764-4_2 · Cited by 1 · see citing works

Erk signaling and chromatin remodeling in MMTV promoter activation by progestins

Vicent, G. P., Zaurín, R., Ballaré, C., Nacht, A. S., & Beato, M. (2009) · Nuclear Receptor Signaling · doi:10.1621/nrs.07008 · Cited by 29 · see citing works

Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activationPreprint

Vicent, G. P., Nacht, A. S., Font-Mateu, J., Castellano, G., Gaveglia, L., Ballaré, C., & Beato, M. (2011) · Genes & Development · doi:10.1101/gad.621811 · Cited by 108 · see citing works

Impact of chromatin structure and dynamics on PR signaling. The initial steps in hormonal gene regulation

Beato, M., & Vicent, G. P. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.09.004 · Cited by 33 · see citing works