The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Maize Inbreds Exhibit High Levels of Copy Number Variation (CNV) and Presence/Absence Variation (PAV) in Genome Content
Open accessAbstract
Following the domestication of maize over the past approximately 10,000 years, breeders have exploited the extensive genetic diversity of this species to mold its phenotype to meet human needs. The extent of structural variation, including copy number variation (CNV) and presence/absence variation (PAV), which are thought to contribute to the extraordinary phenotypic diversity and plasticity of this important crop, have not been elucidated. Whole-genome, array-based, comparative genomic hybridization (CGH) revealed a level of structural diversity between the inbred lines B73 and Mo17 that is unprecedented among higher eukaryotes. A detailed analysis of altered segments of DNA conservatively estimates that there are several hundred CNV sequences among the two genotypes, as well as several thousand PAV sequences that are present in B73 but not Mo17. Haplotype-specific PAVs contain hundreds of single-copy, expressed genes that may contribute to heterosis and to the extraordinary phenotypic diversity of this important crop.
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Cites
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De novo assembly, annotation, and comparative analysis of 26 diverse maize genomes
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Genome-wide patterns of genetic variation among elite maize inbred lines
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Metadata
- Authors
- Springer, N. M., Ying, K., Fu, Y., Ji, T., Yeh, C.-T., Jia, Y., Wu, W., Richmond, T., Kitzman, J., Rosenbaum, H., Iniguez, A. L., Barbazuk, W. B., Jeddeloh, J. A., Nettleton, D., & Schnable, P. S.
- Venue
- PLoS Genetics
- Publisher
- Public Library of Science (PLoS)
- Published
- 2009-11-20
- Volume
- 5
- Issue
- 11
- Pages
- e1000734
- ISSN
- 1553-7390 (ISSN-L)
- 1553-7404
- OpenAlex
- W2106963975
- Cited by
- 540
- References
- 8
- FWCI
- 18.71
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Maize Inbreds Exhibit High Levels of Copy Number Variation (CNV) and Presence/Absence Variation (PAV) in Genome Content. https://app.cochat.ai/papers/10.1371/journal.pgen.1000734
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- Springer, N. M., Ying, K., Fu, Y., Ji, T., Yeh, C.-T., Jia, Y., Wu, W., Richmond, T., Kitzman, J., Rosenbaum, H., Iniguez, A. L., Barbazuk, W. B., Jeddeloh, J. A., Nettleton, D., & Schnable, P. S. (2009). Maize Inbreds Exhibit High Levels of Copy Number Variation (CNV) and Presence/Absence Variation (PAV) in Genome Content. PLoS Genetics. https://doi.org/10.1371/journal.pgen.1000734
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