The Transcription Factors Sox10 and Myrf Define an Essential Regulatory Network Module in Differentiating Oligodendrocytes

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The bHLH Transcription Factors OLIG2 and OLIG1 Couple Neuronal and Glial Subtype Specification

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Sox10, a Novel Transcriptional Modulator in Glial Cells

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Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10Preprint

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Control of oligodendrocyte differentiation by theNkx2.2homeodomain transcription factor

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Deletion of PDK1 in oligodendrocyte lineage cells causes white matter abnormality and myelination defect in the central nervous system

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Recent advances in the regulation mechanism of SOX10

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Progesterone effects on oligodendrocyte differentiation in injured spinal cord

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Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across speciesPreprint

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The Role of Oligodendrocytes in Neurodegenerative Diseases: Unwrapping the Layers

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Neural development and regeneration: it's all in your spinal cord

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Rapid and Efficient Differentiation of Rodent Neural Stem Cells into Oligodendrocyte Progenitor Cells

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Synthetic α-Tocopherol, Compared with Natural α-Tocopherol, Downregulates Myelin Genes in Cerebella of Adolescent Ttpa-null Mice

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Gliomas: a reflection of temporal gliogenic principles

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Playing the Field: Sox10 Recruits Different Partners to Drive Central and Peripheral Myelination

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Identifying circRNA- and lncRNA-associated-ceRNA networks in the hippocampi of rats exposed to PM2.5 using RNA-seq analysis

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Formation of the node of Ranvier by Schwann cells is under control of transcription factor Sox10

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Fmrp regulates oligodendrocyte lineage cell specification and differentiation

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Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders

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Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program

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Pathology of oligodendroglia: An overview

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Differential activity of transcription factor Sox9 in early and adult oligodendroglial progenitor cells

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Dual specificity phosphatase 15 regulates Erk activation in Schwann cells

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A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice

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Crystal structure of the DNA-binding domain of Myelin-gene Regulatory Factor

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Kir4.1 is specifically expressed and active in non‐myelinating Schwann cells

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Molecular and cellular processes disrupted in the early postnatal Down syndrome prefrontal cortex

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Radiation-induced neuropathological changes in the oligodendrocyte lineage with relevant clinical manifestations and therapeutic strategies

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MYRF: A unique transmembrane transcription factor‐ from proteolytic self‐processing to its multifaceted roles in animal development

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Sox8: a multifaceted transcription factor in development and disease

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Transcription Factors and Coregulators in Schwann Cell Differentiation, Myelination, and Remyelination: Implications for Peripheral Neuropathy

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Direct conversion of somatic cells towards oligodendroglial lineage cells: A novel strategy for enhancement of myelin repair

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Shared patterns of glial transcriptional dysregulation link Huntington’s disease and schizophrenia

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The Effect of Saffron Aquatic Extract and Crocin on the Differentiation of Neural Stem Cells Into Oligodendrocyte Precursor Cells

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Electroacupuncture promotes remyelination and alleviates cognitive deficit via promoting OPC differentiation in a rat model of subarachnoid hemorrhage

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Impaired oligodendrogenesis in the white matter of aged mice following diffuse traumatic brain injury

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Transcriptional Fingerprint of Hypomyelination in Zfp191 null and Shiverer ( Mbp shi ) Mice

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Gene expression signature in brain regions exposed to long-term psychosocial stress following acute challenge with cannabinoid drugs

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Ontogenetic oligodendrocyte maturation through gestational iron deprivation: The road not taken

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Understanding the Links among Maternal Diet, Myelination, and Depression: Preclinical and Clinical Overview

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The knowns and many unknowns of CNS immunity in teleost fish

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Clinical application of oligodendrocyte precursor cells for cell-based therapy

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Tmeff2 is expressed in differentiating oligodendrocytes but dispensable for their differentiation in vivo

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Sox9 overexpression exerts multiple stage‐dependent effects on mouse spinal cord development

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Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha

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Transcriptional regulators of the Golli/myelin basic protein locus integrate additive and stealth activities

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Coactivator‐associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development

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Pathologic TDP ‐43 downregulates myelin gene expression in the monkey brain

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A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity

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Evaluating Sex Steroid Hormone Neuroprotection in Spinal Cord Injury in Animal Models: Is It Promising in the Clinic?

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FBXW7 regulates MYRF levels to control myelin capacity and homeostasis in the adult central nervous system

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Lactate-driven H3K27 lactylation promotes Olig2-dependent remyelination and motor recovery after spinal cord injury

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The myelination‐associated G protein‐coupled receptor 37 is regulated by Zfp488, Nkx2.2, and Sox10 during oligodendrocyte differentiation

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Amyloid‐β Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via PKC in the Zebrafish Spinal Cord

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Sox2: A multitasking networker

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Physiology of oligodendroglia

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Deciphering associations between three RNA splicing-related genetic variants and lung cancer risk

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Myelinated axon as a plastic cable regulating brain functions

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Function of Lymphocytes in Oligodendrocyte Development

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Coordinated Regulation of Myelination by Growth Factor and Amino-acid Signaling Pathways

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MicroRNAs dysregulated in multiple sclerosis affect the differentiation of CG-4 cells, an oligodendrocyte progenitor cell line

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The emerging roles of particulate matter-changed non-coding RNAs in the pathogenesis of Alzheimer's disease: A comprehensive in silico analysis and review

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Myelin regulatory factor (MYRF) is a critical early regulator of retinal pigment epithelial development

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Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain

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Functional organization of an Mbp enhancer exposes striking transcriptional regulatory diversity within myelinating glia

Dionne, N., Dib, S., Finsen, B. R., Denarier, É., Kuhlmann, T., Drouin, R., Kokoeva, M. V., Hudson, T. J., Siminovitch, K. A., Friedman, H. C., et al. (2015) · Glia · doi:10.1002/glia.22923 · Cited by 5

SRSF10 regulates oligodendrocyte differentiation during mouse central nervous system development by modulating pre-mRNA splicing

Mu, Y.-W., Wei, Z., Sun, M., Li, J., Jiang, Y., Jiang, H., Ma, A., Zhu, C., & Chen, X. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf455 · Cited by 5

Analysis of the human SOX10 mutation Q377X in mice and its implications for genotype-phenotype correlation in SOX10-related human disease

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Advances in transcription factors related to neuroglial cell reprogramming

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Case Report: De novo variant in myelin regulatory factor in a Chinese child with 46,XY disorder/difference of sex development, cardiac and urogenital anomalies, and short stature

Wang, H., Wu, D., Wu, D., Tian, H., Li, H., Jiang, K., & Zou, C. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.1027832 · Cited by 5

Cooperative multi-view integration with a scalable and interpretable model explainer

Choi, J. J., Kalafut, N. C., Gruenloh, T., Engelman, C. D., Lu, T., & Wang, D. (2025) · Nature Machine Intelligence · doi:10.1038/s42256-025-01111-w · Cited by 4

The Role of Oligodendrocytes in Alzheimer’s Disease Pathogenesis and Therapy

Guo, S., Yu, X., & Zhang, H. (2025) · Neuroglia · doi:10.3390/neuroglia6040046 · Cited by 5

Long-Term Excessive Alcohol Consumption Enhances Myelination in the Mouse Nucleus Accumbens

Liran, M., Fischer, I., Elboim, M., Rahamim, N., Gordon, T., Urshansky, N., Assaf, Y., Barak, B., & Barak, S. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0280-24.2025 · Cited by 4

Dysregulation of Myelination in Focal Cortical Dysplasia Type II of the Human Frontal Lobe

Donkels, C., Häussler, U., Huber, S., Tiesmeyer, N., Demerath, T., Scheiwe, C. F., Shah, M., Heers, M., Urbach, H., Schulze-Bonhage, A., et al. (2024) · Glia · doi:10.1002/glia.24662 · Cited by 5

Genetic analysis of de novo variants reveals sex differences in complex and isolated congenital diaphragmatic hernia and indicates MYRF as a candidate genePreprint

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Early oligodendrocyte dysfunction signature in Alzheimer’s disease: Insights from DNA methylomics and transcriptomics

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Gtf2i-encoded transcription factor Tfii-i regulates myelination via Sox10 and Mbp regulatory elements

Levy, G., Rokach, M., Fischer, I., Kimchi-Feldhorn, O., Shoob, S., Bar, E., Rosenberg, T., Bartman, J., Parnas, H., Grad, M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-63500-4 · Cited by 4

PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development

Waldhauser, V., Baroti, T., Fröb, F., & Wegner, M. (2023) · Cells · doi:10.3390/cells12121556 · Cited by 3

Common Myelin Regulatory Factor Gene Variants Predisposing to Excellence in Sports

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COUP‐TFII plays a role in cAMP ‐induced Schwann cell differentiation and in vitro myelination by up‐regulating Krox20

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Transcriptional networks of transient cell states during human prefrontal cortex development

Singh, A. P., & Tiwari, V. K. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2023.1126438 · Cited by 3

Transcription Factors Sox2 and Sox3 Directly Regulate the Expression of Genes Involved in the Onset of Oligodendrocyte Differentiation

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Fetal Presentation of MYRF ‐Related Cardiac Urogenital Syndrome: An Emerging and Challenging Prenatal Diagnosis

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Sp2 is the only glutamine‐rich specificity protein with minor impact on development and differentiation in myelinating glia

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Signaling pathways that regulate glial development and early migration—oligodendrocytes

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Spatially resolved gene regulatory and disease vulnerability map of the adult Macaque cortexPreprint

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