The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.
Neural Basis of Self and Other Representation in Autism: An fMRI Study of Self-Face Recognition
Open accessAbstract
BACKGROUND: Autism is a developmental disorder characterized by decreased interest and engagement in social interactions and by enhanced self-focus. While previous theoretical approaches to understanding autism have emphasized social impairments and altered interpersonal interactions, there is a recent shift towards understanding the nature of the representation of the self in individuals with autism spectrum disorders (ASD). Still, the neural mechanisms subserving self-representations in ASD are relatively unexplored. METHODOLOGY/PRINCIPAL FINDINGS: We used event-related fMRI to investigate brain responsiveness to images of the subjects' own face and to faces of others. Children with ASD and typically developing (TD) children viewed randomly presented digital morphs between their own face and a gender-matched other face, and made "self/other" judgments. Both groups of children activated a right premotor/prefrontal system when identifying images containing a greater percentage of the self face. However, while TD children showed activation of this system during both self- and other-processing, children with ASD only recruited this system while viewing images containing mostly their own face. CONCLUSIONS/SIGNIFICANCE: This functional dissociation between the representation of self versus others points to a potential neural substrate for the characteristic self-focus and decreased social understanding exhibited by these individuals, and suggests that individuals with ASD lack the shared neural representations for self and others that TD children and adults possess and may use to understand others.
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“Individuals with ASD often show difficulty in evaluating social cues and in appropriately interpreting another person’s experiences or emotions, and may display a preoccupation with self or limited interest in others 14–19.”
From Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time (2021) · cites this paper as [18]
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“Individuals with ASD are often described as having inability to organize social information or appropriately interpret the state and experience of others 14–19.”
From Reduced sociability and social agency encoding in adult Shank3-mutant mice are restored through gene re-expression in real time (2021) · cites this paper as [18]
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Cites
Lord, C., Rutter, M., & Le Couteur, A. (1994) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172145 · Cited by 9,065
(1943) · The Nervous child · Cited by 8,870
The fusiform face area: a module in human extrastriate cortex specialized for face perception
Kanwisher, N., McDermott, J., & Chun, M. M. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-11-04302.1997 · Cited by 7,738
Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., Pickles, A., & Rutter, M. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005592401947 · Cited by 7,520
Empathy for Pain Involves the Affective but not Sensory Components of Pain
Singer, T., Seymour, B., O'Doherty, J., Kaube, H., Dolan, R. J., & Frith, C. D. (2004) · Science · doi:10.1126/science.1093535 · Cited by 3,929
Forman, S. D., Cohen, J. D., Fitzgerald, M., Eddy, W. F., Mintun, M. A., & Noll, D. C. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910330508 · Cited by 3,202
Autistic disturbances of affective contact.
Kanner, L. (1968) · PubMed · Cited by 2,282
A unifying view of the basis of social cognition
GALLESE, V, KEYSERS, C., & RIZZOLATTI, G. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.07.002 · Cited by 2,236
Both of Us Disgusted in My Insula
Wicker, B., Keysers, C., Plailly, J., Royet, J.-P., Gallese, V., & Rizzolatti, G. (2003) · Neuron · doi:10.1016/s0896-6273(03)00679-2 · Cited by 2,185
A three-dimensional statistical analysis for CBF activation studies in human brain
Worsley, K. J., Evans, A. C., Marrett, S., & Neelin, P. (1992) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1992.127 · Cited by 2,036
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- T Behrens, 2003, Multi-subject null hypothesis testing using a fully bayesian framework: theory., Hum Brain Mapp
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Items 101–118 of 118
Nijhof, A. D. (2017) · Ghent University Academic Bibliography (Ghent University)
Computational Multimedia for Video Self Modeling
Shen, J. (2014) · UKnowledge (University of Kentucky)
Ohata, R., Asai, T., Kadota, H., Shigemasu, H., Ogawa, K., & Imamizu, H. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/483420
The Development of Face Morphing Task to Assess Self Other Differentiation
Karan, E. (2019) · CUNY Academic Works (City University of New York)
Cygan, H. B. (2019) · Psychologia Rozwojowa · doi:10.4467/20843879pr.19.019.11725
Xuan, B., Li, S., & Yang, L. (2021) · Research Square · doi:10.21203/rs.3.rs-870951/v1
Eye-tracking explorations of attention to faces for communicative cues in Autism Spectrum Disorders
Gillespie‐Smith, K. (2011) · Stirling Online Research Repository (University of Stirling)
Applications of fMRI to Psychiatry
Lopez-Larson, M. P., & Yurgelun-Todd, D. A. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1995-6_17
Kilroy, E. (2021) · Springer eBooks · doi:10.1007/978-3-319-91280-6_752
In conversation with Lucina Q. Uddin
Zarate, J. M. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01348-x
Functional Neuroradiology of Psychiatric Diseases
Nucifora, P. G. P. (2023) · Springer eBooks · doi:10.1007/978-3-031-10909-6_16
Wang, Y., Liu, Y., Kendrick, K. M., & Feng, T. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4606946
The Therapeutic Usefulness of Video Narrative Playback: A Pilot Comparative Effectiveness Study
Lcsw, R., & Leas, S. (2015) · ScholarlyCommons (University of Pennsylvania)
Odors modulate self face perception and frontal ERP responses
Yoon, S., Moon, S., Kim, K., Bae, J., Lee, J., & Moon, C. (2026) · Scientific Reports · doi:10.1038/s41598-026-35683-3
Face Recognition and Reading in Individuals with Autism Spectrum Disorders
Matson, J. L. (2026) · Autism and child psychopathology series · doi:10.1007/978-3-032-11141-8_5
Fang, W., Eguchi, K., & Fukui, T. (2026) · Psychological Research · doi:10.1007/s00426-026-02335-0
The active self in autism: multisensory and sensorimotor foundations of bodily self-representation
Najafabadi, A. J., & Rastegari, A. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-08756-w · Cited by 1
Metadata
- Authors
- Uddin, L. Q., Davies, M. S., Scott, A. A., Zaidel, E., Bookheimer, S. Y., Iacoboni, M., & Dapretto, M.
- Affiliations
- University of California, Los Angeles (US)
- Corresponding author
- Uddin, Lucina Q.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2008-10-29
- Volume
- 3
- Issue
- 10
- Pages
- e3526
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC2568959
- OpenAlex
- W2005551003
- Cited by
- 118
- References
- 66
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 3 · 2023: 6 · 2022: 6 · 2021: 6 · 2020: 5 · 2019: 4 · 2018: 5 · 2017: 7 · 2016: 6 · 2015: 7 · 2014: 10 · 2013: 7 · 2012: 7
- FWCI
- 5.69
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by)
- Funders
- National Science Foundation
- Brain Mapping Support Foundation
- National Institutes of Health (RR13642)
- National Center for Research Resources (P41RR013642, RR12169, RR 13642, RR00865, M01RR000865, C06RR012169)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P01HD035470)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Face Recognition and Perception
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Keywords
- autism spectrum disorder, self-face recognition, self and other representations, face perception, self-focus, social cognition, children with autism
- MeSH terms
- Adolescent, Autistic Disorder, Behavior, Brain Mapping, Child, Face, Facial Expression, Humans, Magnetic Resonance Imaging, Male, Mental Processes, Pattern Recognition, Visual, Photic Stimulation, Self Concept, Social Perception
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