Increased Risk of Fragility Fractures among HIV Infected Compared to Uninfected Male Veterans
Open accessAbstract
BACKGROUND: HIV infection has been associated with an increased risk of fragility fracture. We explored whether or not this increased risk persisted in HIV infected and uninfected men when controlling for traditional fragility fracture risk factors. METHODOLOGY/PRINCIPAL FINDINGS: Cox regression models were used to assess the association of HIV infection with the risk for incident hip, vertebral, or upper arm fracture in male Veterans enrolled in the Veterans Aging Cohort Study Virtual Cohort (VACS-VC). We calculated adjusted hazard ratios comparing HIV status and controlling for demographics and other established risk factors. The sample consisted of 119,318 men, 33% of whom were HIV infected (34% aged 50 years or older at baseline, and 55% black or Hispanic). Median body mass index (BMI) was lower in HIV infected compared with uninfected men (25 vs. 28 kg/m²; p<0.0001). Unadjusted risk for fracture was higher among HIV infected compared with uninfected men [HR: 1.32 (95% CI: 1.20, 1.47)]. After adjusting for demographics, comorbid disease, smoking and alcohol abuse, HIV infection remained associated with an increased fracture risk [HR: 1.24 (95% CI: 1.11, 1.39)]. However, adjusting for BMI attenuated this association [HR: 1.10 (95% CI: 0.97, 1.25)]. The only HIV-specific factor associated with fragility fracture was current protease inhibitor use [HR: 1.41 (95% CI: 1.16, 1.70)]. CONCLUSIONS/SIGNIFICANCE: HIV infection is associated with fragility fracture risk. This risk is attenuated by BMI.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
HIV-associated, Non-AIDS (HANA) conditions include cardiovascular disease, a number of infectious and noninfectious cancers, osteopenia/osteoporosis, liver disease, renal disease, and neurocognitive decline.
“These include cardiovascular disease (6), a number of infectious and noninfectious cancers (7,8), osteopenia/osteoporosis (9), liver disease (10), renal disease (11,12) and neurocognitive decline.”
HANA conditions include cardiovascular disease, infectious and noninfectious cancers, osteopenia/osteoporosis, liver cirrhosis, and renal disease.
“These include cardiovascular disease, a number of infectious and noninfectious cancers (7,8), osteopenia/osteoporosis(9), liver cirrhosis (10), and renal disease (11, 12).”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The Measurement of Observer Agreement for Categorical Data
Landis, J. R., & Koch, G. G. (1977) · Biometrics · doi:10.2307/2529310 · Cited by 81,148 · see citing works
RUBIN, D. B. (1976) · Biometrika · doi:10.1093/biomet/63.3.581 · Cited by 9,925 · see citing works
Sterne, J. A. C., White, I. R., Carlin, J. B., Spratt, M., Royston, P., Kenward, M. G., Wood, A. M., & Carpenter, J. R. (2009) · BMJ · doi:10.1136/bmj.b2393 · Cited by 7,299 · see citing works
FRAX™ and the assessment of fracture probability in men and women from the UK
Kanis, J. A., Johnell, O., Oden, A., Johansson, H., & McCloskey, E. (2008) · Osteoporosis International · doi:10.1007/s00198-007-0543-5 · Cited by 2,467 · see citing works
Body mass index as a predictor of fracture risk: A meta-analysis
De Laet, C., Kanis, J. A., Odén, A., Johanson, H., Johnell, O., Delmas, P., Eisman, J. A., Kroger, H., Fujiwara, S., Garnero, P., et al. (2005) · Osteoporosis International · doi:10.1007/s00198-005-1863-y · Cited by 1,622 · see citing works
Use of Inhaled Corticosteroids and Risk of Fractures
van Staa, T. P., Leufkens, H. G. M., & Cooper, C. C. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.3.581 · Cited by 1,297 · see citing works
Use of oral corticosteroids and risk of fractures
Van Staa, T. P., Leufkens, H. G. M., Abenhaim, L., Zhang, B., & Cooper, C. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.6.993 · Cited by 1,263 · see citing works
Liver-Related Deaths in Persons Infected With the Human Immunodeficiency Virus
The Data Collection on Adverse Events of Anti-HIV Drugs Study Group* (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.15.1632 · Cited by 1,115 · see citing works
Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival
Kitahata, M. M., Gange, S. J., Abraham, A. G., Merriman, B., Saag, M. S., Justice, A. C., Hogg, R. S., Deeks, S. G., Eron, J. J., Brooks, J. T., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0807252 · Cited by 1,105 · see citing works
Self-citationBone Mineral Density Thresholds for Pharmacological Intervention to Prevent Fractures
Siris, E. S., Chen, Y.-T., Abbott, T. A., Barrett-Connor, E. L., Miller, P. D., Wehren, L. E., & Berger, M. L. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.10.1108 · Cited by 1,093 · see citing works
Long-Term Risk of Osteoporotic Fracture in Malmö
Kanis, J. A., Johnell, O., Oden, A., Sernbo, I., Redlund-Johnell, I., Dawson, A., De Laet, C., & Jonsson, B. (2000) · Osteoporosis International · doi:10.1007/s001980070064 · Cited by 1,027 · see citing works
Antiretroviral therapy and the prevalence of osteopenia and osteoporosis: a meta-analytic review
Brown, T. T., & Qaqish, R. B. (2006) · AIDS · doi:10.1097/qad.0b013e32801022eb · Cited by 924 · see citing works
Alcohol intake as a risk factor for fracture
Kanis, J. А., Johansson, H., Johnell, O., Odén, A., Laet, C. E. D. H. D., Eisman, J. A., Pols, H. A. P., & Tenenhouse, A. (2004) · Osteoporosis International · doi:10.1007/s00198-004-1734-y · Cited by 629 · see citing works
Accelerated bone mineral loss in HIV-infected patients receiving potent antiretroviral therapy
Tebas, P., Powderly, W. G., Claxton, S., Marin, D., Tantisiriwat, W., Teitelbaum, S. L., & Yarasheski, K. E. (2000) · AIDS · doi:10.1097/00002030-200003100-00005 · Cited by 532 · see citing works
Hippisley-Cox, J., & Coupland, C. (2009) · British medical journal · doi:10.1136/bmj.b4229 · Cited by 500 · see citing works
Triant, V. A., Brown, T. T., Lee, H., & Grinspoon, S. K. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0828 · Cited by 489 · see citing works
The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals
The HIV-CAUSAL Collaboration (2009) · AIDS · doi:10.1097/qad.0b013e3283324283 · Cited by 466 · see citing works
Use of proton pump inhibitors and risk of osteoporosis-related fractures
Targownik, L. E., Lix, L. M., Metge, C. J., Prior, H. J., Leung, S., & Leslie, W. D. (2008) · Canadian Medical Association Journal · doi:10.1503/cmaj.071330 · Cited by 436 · see citing works
Identification of Osteopenic Women at High Risk of Fracture: The OFELY Study
Sornay‐Rendu, E., Munoz, F., Garnero, P., Duboeuf, F., & Delmas, P. D. (2005) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.050609 · Cited by 392 · see citing works
Increased COPD Among HIV-Positive Compared to HIV-Negative Veterans
Crothers, K. A., Butt, A. A., Gibert, C. L., Rodriguez‐Barradas, M. C., Crystal, S., & Justice, A. C. (2006) · CHEST Journal · doi:10.1378/chest.130.5.1326 · Cited by 369 · see citing works
Self-citationThe population burden of fractures originates in women with osteopenia, not osteoporosis
Pasco, J. A., Seeman, E., Henry, M. J., Merriman, E. N., Nicholson, G. C., & Kotowicz, M. A. (2006) · Osteoporosis International · doi:10.1007/s00198-006-0135-9 · Cited by 364 · see citing works
Fragility Fractures and the Osteoporosis Care Gap: An International Phenomenon
Giangregorio, L., Παπαϊωάννου, Α., Cranney, A., Zytaruk, N. L., & Adachi, J. D. (2006) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2005.11.001 · Cited by 325 · see citing works
Simpson, J. (1977) · The Lancet · doi:10.1016/s0140-6736(77)91386-1 · Cited by 316 · see citing works
Nguyen, T. V., Sambrook, P. N., & Eisman, J. A. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.6.587 · Cited by 298 · see citing works
Wang, G. C., Kao, W. H. L., Murakami, P. N., Xue, Q., Chiou, R. B., Detrick, B., McDyer, J. F., Semba, R. D., Casolaro, V., Walston, J. D., et al. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq062 · Cited by 266 · see citing works
Development and Verification of a “Virtual” Cohort Using the National VA Health Information System
Fultz, S. L., Skanderson, M., Mole, L. A., Gandhi, N. R., BRYANT, K. J., Crystal, S., & Justice, A. C. (2006) · Medical Care · doi:10.1097/01.mlr.0000223670.00890.74 · Cited by 257 · see citing works
Self-citationArnsten, J. H., Freeman, R., Howard, A. A., Floris-Moore, M., Lo, Y., & Klein, R. S. (2007) · AIDS · doi:10.1097/qad.0b013e3280148c05 · Cited by 251 · see citing works
Decreased bone mineral density in HIV-infected patients is independent of antiretroviral therapy
Bruera, D., Luna, N., David, D. O., Bergoglio, L. M., & Zamudio, J. (2003) · AIDS · doi:10.1097/00002030-200309050-00010 · Cited by 240 · see citing works
Duvivier, C., Kolta, S., Assoumou, L., Ghosn, J., Rozenberg, S., Murphy, R. L., Katlama, C., & Costagliola, D. G. (2009) · AIDS · doi:10.1097/qad.0b013e328328f789 · Cited by 239 · see citing works
Consequences of hip fracture on activities of daily life and residential needs
Osnes, E. K., Lofthus, C. M., Meyer, H. E., Falch, J. A., Nordsletten, L., Cappelen, I., & Kristiansen, I. (2004) · Osteoporosis International · doi:10.1007/s00198-003-1583-0 · Cited by 237 · see citing works
Reduced bone mineral density in HIV-infected patients: prevalence and associated factors
Cazanave, C., Dupon, M., Aurillac-Lavignolle, V., Barthe, N., Lawson‐Ayayi, S., Mehsen, N., Mercié, P., Morlat, P., Thiébaut, R., & Dabis, F. (2008) · AIDS · doi:10.1097/qad.0b013e3282f423dd · Cited by 217 · see citing works
Buhr, A. J., & Cooke, A. M. (1959) · The Lancet · doi:10.1016/s0140-6736(59)92306-2 · Cited by 216 · see citing works
Continuous antiretroviral therapy decreases bone mineral density
Grund, B., Peng, G., Gibert, C. L., Hoy, J., Isaksson, R., Shlay, J. C., Martínez, E., Reiss, P., Visnegarwala, F., & Carr, A. D. (2009) · AIDS · doi:10.1097/qad.0b013e32832c1792 · Cited by 212 · see citing works
Self-citationInvestigation and treatment of osteoporosis in patients with fragility fractures.
Hajcsar, E. E., HAWKER, G. A., & Bogoch, E. R. (2000) · Europe PMC (PubMed Central) · Cited by 188 · see citing works
Medical Disease and Alcohol Use Among Veterans With Human Immunodeficiency Infection
Justice, A. C., Lasky, E., McGinnis, K. A., Skanderson, M., Conigliaro, J. C., Fultz, S. L., Crothers, K. A., Rabeneck, L., Rodriguez‐Barradas, M. C., Weissman, S., et al. (2006) · Medical Care · doi:10.1097/01.mlr.0000228003.08925.8c · Cited by 159 · see citing works
Self-citationBMD Is Reduced in HIV-Infected Men Irrespective of Treatment
Amiel, C., Ostertag, A., Slama, L., Baudoin, C., N'Guyen, T., Lajeunie, E., Neit-Ngeilh, L., Rozenbaum, W., & De Vernejoul, M. (2004) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.0301246 · Cited by 150 · see citing works
Heart Failure Is a Risk Factor for Orthopedic Fracture
van Diepen, S., Majumdar, S. R., Bakal, J. A., McAlister, F. A., & Ezekowitz, J. A. (2008) · Circulation · doi:10.1161/circulationaha.108.784009 · Cited by 148 · see citing works
Παπαϊωάννου, Α., Kennedy, C. C., Ioannidis, G., Gao, Y., Sawka, A. M., Goltzman, D., Tenenhouse, A., Pickard, L. E., Olszynski, W. P., Davison, K. S., et al. (2007) · Osteoporosis International · doi:10.1007/s00198-007-0483-0 · Cited by 146 · see citing works
Calmy, A., Fux, C. A., Norris, R., Vallier, N., Delhumeau, C., Samaras, K., Hesse, K., Hirschel, B. J., Cooper, D. A., & Carr, A. D. (2009) · The Journal of Infectious Diseases · doi:10.1086/644785 · Cited by 143 · see citing works
HIV Infection and Bone Mineral Density in Middle-Aged Women
Arnsten, J. H., Freeman, R., Howard, A. A., Floris-Moore, M., Santoro, N. F., & Schoenbaum, E. E. (2006) · Clinical Infectious Diseases · doi:10.1086/501015 · Cited by 137 · see citing works
Osteopenia in HIV-infected Women Prior to Highly Active Antiretroviral Therapy
Teichmann, J., Stephan, E., Lange, U., Discher, T., Friese, G., Lohmeyer, J., Stracke, H. H. G., & Bretzel, R. G. (2003) · Journal of Infection · doi:10.1053/jinf.2002.1109 · Cited by 131 · see citing works
Bolland, M. J., Grey, A. B., Gamble, G. D., & Reid, I. R. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1660 · Cited by 126 · see citing works
Collins, T. C., Ewing, S. K., Diem, S. J., Taylor, B. C., ORWOLL, E. S., Cummings, S. R., Strotmeyer, E. S., & Ensrud, K. E. (2009) · Circulation · doi:10.1161/circulationaha.108.820993 · Cited by 125 · see citing works
Prior, J. C., Burdge, D. R., Maan, E. J., Milner, R., Hankins, C. A., Klein, M. B., & Walmsley, S. L. (2007) · Osteoporosis International · doi:10.1007/s00198-007-0428-7 · Cited by 122 · see citing works
Bone mineral density predicts osteoporotic fractures in elderly men: the MINOS study
Szulc, P., Munoz, F., Duboeuf, F., Marchand, F., & Delmas, P. D. (2005) · Osteoporosis International · doi:10.1007/s00198-005-1970-9 · Cited by 113 · see citing works
A comparison of analytic methods for non-random missingness of outcome data
Crawford, S. L. (1995) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(94)00124-9 · Cited by 110 · see citing works
Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1-infected adults
Collin, F., Duval, X., Moing, V. L., Piroth, L., Kaied, F. A., Massip, P., Villes, V., Chêne, G., & Raffi, F. (2009) · AIDS · doi:10.1097/qad.0b013e3283292195 · Cited by 105 · see citing works
Hoffmann, M. W., Berger, J. R., Nath, A., & Rayens, M. K. (2000) · Journal of NeuroVirology · doi:10.3109/13550280009015825 · Cited by 88 · see citing works
Fractures of the distal forearm in young adults: An epidemiologic description of 341 patients
Lindau, T., Aspenberg, P., Arner, M., Redlund-Johnell, I., & Hagberg, L. (1999) · Acta Orthopaedica Scandinavica · doi:10.3109/17453679909011248 · Cited by 83 · see citing works
Cheung, A. M., & Detsky, A. S. (2008) · JAMA · doi:10.1001/jama.299.12.1468 · Cited by 71 · see citing works
Development and Verification of TAPM
Hurley, P. J. (2008) · NATO security through science series. C, Environmental security (Online)/NATO security through science series. C, Environmental security (Print) · doi:10.1007/978-1-4020-8453-9_23 · Cited by 62 · see citing works
Bone mineral density remains stable in HAART‐treated HIV‐infected men over 2 years
Bolland, M. J., Grey, A. B., Horne, A. M., Briggs, S. E., Thomas, M. G., Ellis-Pegler, R. B., Woodhouse, A. F., Gamble, G. D., & Reid, I. R. (2007) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2007.02875.x · Cited by 53 · see citing works
McComsey, G. A., Huang, J. S., Woolley, I. J., Young, B., Sax, P. E., Gerber, M., Swindells, S., Bonilla, H. F., & Gopalakrishnan, G. (2004) · Journal of the International Association of Physicians in AIDS Care · doi:10.1177/154510970400300303 · Cited by 42 · see citing works
Epidemiology and economic burden of viral hepatitis: an observational population based study
Steinke, D. T. (2002) · Gut · doi:10.1136/gut.50.1.100 · Cited by 38 · see citing works
Gallant, J. E., Chaisson, R. E., & Moore, R. D. (1998) · CHEST Journal · doi:10.1378/chest.114.5.1258 · Cited by 35 · see citing works
Bone Changes and Fracture Risk in Individuals Infected With HIV
Warriner, A. H., & Mugavero, M. J. (2010) · Current Rheumatology Reports · doi:10.1007/s11926-010-0099-9 · Cited by 20 · see citing works
IV Increasing age and fractures of the distal radius
McQueen, M. M., & COURT-BROWN, C. M. (2003) · Current Orthopaedics · doi:10.1016/s0268-0890(03)00097-5 · Cited by 15 · see citing works
The effect of combined antiretroviral therapy on the overall mortality of HIV-infected individuals
Ray, M., Logan, R. W., Sterne, J. A. C., Hernández–Dı́az, S., Robins, J. M., Sabin, C. A., Bansi‐Matharu, L., van Sighem, A., Wolf, D., Costagliola, D. G., et al. (2010) · Archive ouverte UNIGE (University of Geneva) · Cited by 13 · see citing works
Self-citationRitonavir-associated hyperparathyroidism, osteopenia and bone pain
Piliero, P. J., & Gianoukakis, A. G. (2002) · AIDS · doi:10.1097/00002030-200207260-00019 · Cited by 12 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
HIV-1 infection accelerates age according to the epigenetic clock
Horvath, S., & Levine, A. J. (2015) · Journal of Infectious Diseases · doi:10.1093/infdis/jiv277 · Cited by 556 · see citing works
High, K. P., Brennan-Ing, M., Clifford, D. B., Cohen, M. H., Currier, J., Deeks, S. G., Deren, S., Effros, R. B., Gebo, K., Goronzy, J. J., et al. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31825a3668 · Cited by 522 · see citing works
Self-citationBedimo, R., Maalouf, N. M., Zhang, S., Drechsler, H., & Tebas, P. (2012) · AIDS · doi:10.1097/qad.0b013e32835192ae · Cited by 324 · see citing works
Weitzmann, M. (2013) · Scientifica · doi:10.1155/2013/125705 · Cited by 270 · see citing works
Physiological and pathophysiological bone turnover — role of the immune system
Weitzmann, M. N., & Ofotokun, I. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.91 · Cited by 243 · see citing works
The Next Therapeutic Challenge in HIV: Polypharmacy
Edelman, E. J., Gordon, K. S., Glover, J. G., McNicholl, I. R., Fiellin, D. A., & Justice, A. C. (2013) · Drugs & Aging · doi:10.1007/s40266-013-0093-9 · Cited by 227 · see citing works
Self-citationComorbidities Among US Patients With Prevalent HIV Infection—A Trend Analysis
Gallant, J. E., Hsue, P. Y., Shreay, S., & Meyer, N. M. (2017) · The Journal of Infectious Diseases · doi:10.1093/infdis/jix518 · Cited by 220 · see citing works
Predictive Accuracy of the Veterans Aging Cohort Study Index for Mortality With HIV Infection
Justice, A. C., Modur, S. P., Tate, J. P., Althoff, K. N., Jacobson, L. P., Gebo, K. A., Kitahata, M. M., Horberg, M. A., Brooks, J. T., Buchacz, K. A., et al. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e31827df36c · Cited by 220 · see citing works
Self-citationHIV Infection and Older Americans: The Public Health Perspective
Brooks, J. T., Buchacz, K. A., Gebo, K. A., & Mermin, J. (2012) · American Journal of Public Health · doi:10.2105/ajph.2012.300844 · Cited by 203 · see citing works
Weitzmann, M. (2017) · Toxicologic pathology (Print) · doi:10.1177/0192623317735316 · Cited by 177 · see citing works
Functional Impairment, Disability, and Frailty in Adults Aging with HIV-Infection
Erlandson, K. M., Schrack, J. A., Jankowski, C. M., Brown, T. T., & Campbell, T. (2014) · Current HIV/AIDS Reports · doi:10.1007/s11904-014-0215-y · Cited by 159 · see citing works
Incidence of low and high-energy fractures in persons with and without HIV infection
Hansen, A. E., Gerstoft, J., Kronborg, G., Larsen, C. S., Pedersen, C., Pedersen, G., & Obel, N. (2011) · AIDS · doi:10.1097/qad.0b013e32834ed8a7 · Cited by 147 · see citing works
Incident fractures in HIV-infected individuals
Shiau, S., Broun, E. C., Arpadi, S. M., & Yin, M. T. (2013) · AIDS · doi:10.1097/qad.0b013e328361d241 · Cited by 147 · see citing works
Self-citationGüerri‐Fernández, R., Vestergaard, P., Carbonell-Abella, C., Knobel, H., Avilés, F. F., Soria-Castro, A., Nogués, X., Prieto‐Alhambra, D., & Díez‐Pérez, A. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1874 · Cited by 133 · see citing works
Titanji, K., Vunnava, A., Sheth, A. N., Lahiri, C. D., Lennox, J. L., Sanford, S. E., Foster, A., Knežević, A., Easley, K. A., Weitzmann, M. N., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004497 · Cited by 133 · see citing works
Churchill, D. R., Waters, L. J., Ahmed, N., Angus, B., Boffito, M., Bower, M., Dunn, D. T., Edwards, S., Emerson, C., Fidler, S. J., et al. (2016) · HIV Medicine · doi:10.1111/hiv.12426 · Cited by 131 · see citing works
Vitamin D and Calcium Attenuate Bone Loss With Antiretroviral Therapy Initiation
Overton, E. T., Chan, E. S., Brown, T. T., Tebas, P., McComsey, G. A., Melbourne, K. M., Napoli, A., Hardin, W. R., Ribaudo, H. J., & Yin, M. T. (2015) · Annals of Internal Medicine · doi:10.7326/m14-1409 · Cited by 122 · see citing works
Self-citationBone loss in the HIV-infected patient: evidence, clinical implications, and treatment strategies.
Harris, V. W., & Brown, T. (2012) · Journal of Infectious Diseases · doi:10.1093/infdis/jis199 · Cited by 122 · see citing works
Receipt of Opioid Analgesics by HIV-Infected and Uninfected Patients
Edelman, E. J., Gordon, K. S., Becker, W. C., Goulet, J. L., Skanderson, M., Gaither, J. R., Braden, J. B., Gordon, A. J., Kerns, R. D., Justice, A. C., et al. (2012) · Journal of General Internal Medicine · doi:10.1007/s11606-012-2189-z · Cited by 112 · see citing works
Self-citationGrant, P., Kitch, D. W., McComsey, G. A., Dubé, M. P., Haubrich, R., Huang, J. S., Riddler, S. A., Tebas, P., Zolopa, A. R., Collier, A. C., et al. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit538 · Cited by 112 · see citing works
Levine, A. J., Quach, A., Moore, D. J., Achim, C. L., Soontornniyomkij, V., Masliah, E., Singer, E. J., Gelman, B. B., Nemanim, N. M., & Horvath, S. (2015) · Journal of NeuroVirology · doi:10.1007/s13365-015-0406-3 · Cited by 112 · see citing works
Physiologic Frailty and Fragility Fracture in HIV-Infected Male Veterans
Womack, J. A., Goulet, J. L., Gibert, C. L., Brandt, C., Skanderson, M., Gulanski, B., Rimland, D., Rodriguez‐Barradas, M. C., Tate, J., Yin, M. T., et al. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit056 · Cited by 109 · see citing works
Self-citationAkgün, K. M., Gordon, K. S., Pisani, M. A., Fried, T. R., McGinnis, K. A., Tate, J. P., Butt, A. A., Gibert, C. L., Huang, L., Rodriguez‐Barradas, M. C., et al. (2012) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e318278f3fa · Cited by 105 · see citing works
Self-citationOfotokun, I., McIntosh, E. B., & Weitzmann, M. N. (2011) · Current HIV/AIDS Reports · doi:10.1007/s11904-011-0099-z · Cited by 99 · see citing works
Ofotokun, I., Titanji, K., Vunnava, A., Roser-Page, S., Vikulina, T., Villinger, F., Rogers, K., Sheth, A., Lahiri, C. D., Lennox, J., et al. (2016) · AIDS (London) · doi:10.1097/qad.0000000000000918 · Cited by 94 · see citing works
Akgün, K. M., Tate, J. P., Crothers, K. A., Crystal, S., Leaf, D. A., Womack, J. A., Brown, T. T., Justice, A. C., & Oursler, K. K. (2014) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000341 · Cited by 91 · see citing works
Self-citationPrieto-Alhambra, D., Güerri-Fernández, R., de Vries, F., Lalmohamed, A., Bazelier, M., Starup-Linde, J., Diez-Perez, A., Cooper, C., & Vestergaard, P. (2014) · Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000112 · Cited by 81 · see citing works
Increased Fracture Incidence in Middle-Aged HIV-Infected and HIV-Uninfected Women
Sharma, A., Shi, Q., Hoover, D. R., Anastos, K., Tien, P. C., Young, M., Cohen, M. H., Golub, E. T., Gustafson, D., & Yin, M. T. (2015) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000674 · Cited by 88 · see citing works
Self-citationRole of T cell reconstitution in HIV-1 antiretroviral therapy-induced bone loss
Ofotokun, I., Titanji, K., Vikulina, T., Roser-Page, S., Yamaguchi, M., Zayzafoon, M., Williams, I., & Weitzmann, M. (2015) · Nature Communications · doi:10.1038/ncomms9282 · Cited by 78 · see citing works
Akgün, K. M., Tate, J. P., Pisani, M. A., Fried, T. R., Butt, A. A., Gibert, C. L., Huang, L., Rodriguez‐Barradas, M. C., Rimland, D., Justice, A. C., et al. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827caa46 · Cited by 80 · see citing works
Self-citationKasonde, M., Niska, R. W., Rose, C. E., Henderson, F. L., Segolodi, T. M., Turner, K., Smith, D. K., Thigpen, M. C., & Paxton, L. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090111 · Cited by 79 · see citing works
Effects of Smoking on Non-AIDS-Related Morbidity in HIV-Infected Patients
Shirley, D. K., Kaner, R. J., & Glesby, M. J. (2013) · Clinical Infectious Diseases · doi:10.1093/cid/cit207 · Cited by 79 · see citing works
Bone mineral density in children and adolescents with perinatal HIV infection
DiMeglio, L. A., Wang, J., Siberry, G. K., Miller, T. L., Geffner, M. E., Hazra, R., Borkowsky, W., Chen, J. S., Dooley, L. B., Patel, K., et al. (2012) · AIDS · doi:10.1097/qad.0b013e32835a9b80 · Cited by 77 · see citing works
HIV infection and bone disease
Compston, J. E. (2016) · Journal of Internal Medicine · doi:10.1111/joim.12520 · Cited by 77 · see citing works
Fractures after antiretroviral initiation
Yin, M. T., Kendall, M. A., Wu, X., Tassiopoulos, K., Hochberg, M. C., Huang, J. S., Glesby, M. J., Bolívar, H., & McComsey, G. A. (2012) · AIDS · doi:10.1097/qad.0b013e328359a8ca · Cited by 75 · see citing works
Self-citationA Case-Controlled Study of Successful Aging in Older HIV-Infected Adults
Moore, R. C., Moore, D. J., Thompson, W. K., Vahia, I. V., Grant, I., & Jeste, D. V. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12m08100 · Cited by 73 · see citing works
Kooij, K. W., Wit, F. W. N. M., Bisschop, P. H. L. T., Schouten, J., Stolte, I. G., Prins, M., van der Valk, M., Prins, J. M., van Eck‐Smit, B. L. F., Lips, P. T. A. M., et al. (2014) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiu499 · Cited by 64 · see citing works
Childs, K. E., Welz, T., Samarawickrama, A., & Post, F. A. (2011) · AIDS · doi:10.1097/qad.0b013e32834f324b · Cited by 62 · see citing works
Moyle, G. J., Stellbrink, H., Compston, J. E., Orkin, C. M., Arribas, J. R., Domingo, P., Granier, C., Pearce, H., Sedani, S., Gartland, M., et al. (2013) · Antiviral Therapy · doi:10.3851/imp2667 · Cited by 61 · see citing works
Titanji, K. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.01851 · Cited by 61 · see citing works
Relationship of physical function and quality of life among persons aging with HIV infection
Erlandson, K. M., Allshouse, A. A., Jankowski, C. M., MaWhinney, S., Kohrt, W. M., & Campbell, T. (2014) · AIDS · doi:10.1097/qad.0000000000000384 · Cited by 61 · see citing works
High prevalence of radiological vertebral fractures in HIV-infected males
Torti, C., Mazziotti, G., Soldini, P., Focà, E., Maroldi, R., Gotti, D., Carosi, G., & Giustina, A. (2011) · Endocrine · doi:10.1007/s12020-011-9586-7 · Cited by 60 · see citing works
The role of HIV and antiretroviral therapy in bone disease.
Gutiérrez, F., & Masiá, M. (2011) · PubMed · Cited by 55 · see citing works
Fracture Prediction With Modified-FRAX in Older HIV-Infected and Uninfected Men
Yin, M. T., Shiau, S., Rimland, D., Gibert, C. L., Bedimo, R., Rodriguez‐Barradas, M. C., Harwood, K., Aschheim, J., Justice, A. C., & Womack, J. A. (2016) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000998 · Cited by 55 · see citing works
Self-citationAn increased rate of fracture occurs a decade earlier in HIV+ compared with HIV− men
Gonciulea, A. R., Wang, R., Althoff, K. N., Palella, F. J., Lake, J. E., Kingsley, L., & Brown, T. T. (2017) · AIDS · doi:10.1097/qad.0000000000001493 · Cited by 54 · see citing works
Moran, C. A., Weitzmann, M. N., & Ofotokun, I. (2017) · Current treatment options in infectious diseases/Current treatment options in infectious disease · doi:10.1007/s40506-017-0109-9 · Cited by 53 · see citing works
Chang, C., Chan, Y.-L., Pramukti, I., Ko, N., & Tai, T. (2021) · Archives of Osteoporosis · doi:10.1007/s11657-021-00903-y · Cited by 55 · see citing works
Self-citationProton Pump Inhibitors and Risk of Bone Fractures
Leontiadis, G. I., & Moayyedi, P. (2014) · Current Treatment Options in Gastroenterology · doi:10.1007/s11938-014-0030-y · Cited by 52 · see citing works
The protease inhibitors and HIV-associated bone loss
Moran, C. A., Weitzmann, M. N., & Ofotokun, I. (2016) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000260 · Cited by 52 · see citing works
The Hidden Burden of Fractures in People Living With HIV
Premaor, M. O., & Compston, J. E. (2018) · JBMR Plus · doi:10.1002/jbm4.10055 · Cited by 52 · see citing works
Osteoporosis and Bone Health in HIV
Powderly, W. G. (2012) · Current HIV/AIDS Reports · doi:10.1007/s11904-012-0119-7 · Cited by 51 · see citing works
Brown, T. T., Chen, Y., Currier, J. S., Ribaudo, H. J., Rothenberg, J., Dubé, M. P., Murphy, R. L., Stein, J. H., & McComsey, G. A. (2013) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e318295eb1d · Cited by 49 · see citing works
Lessons learned from the first wave of aging with HIV
Justice, A. C., & Braithwaite, R. S. (2012) · AIDS · doi:10.1097/qad.0b013e3283558500 · Cited by 48 · see citing works
Self-citationThe effects of untreated and treated HIV infection on bone disease
Cotter, A. G., & Mallon, P. W. G. (2013) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000028 · Cited by 48 · see citing works
Mulligan, K. M., Harris, D. R., Emmanuel, P. J., Fielding, R. A., Worrell, C., Kapogiannis, B. G., Monte, D., Sleasman, J. W., Wilson, C. M., Aldrovandi, G. M., et al. (2012) · Clinical Infectious Diseases · doi:10.1093/cid/cis455 · Cited by 48 · see citing works
Self-citationPerspectives on menopause and women with HIV
Loutfy, M. R., Andany, N., Kennedy, V. L., & Aden, M. (2016) · International Journal of Women s Health · doi:10.2147/ijwh.s62615 · Cited by 47 · see citing works
Maalouf, N. M., Zhang, S., Drechsler, H., Brown, G., Tebas, P., & Bedimo, R. (2013) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1988 · Cited by 46 · see citing works
Rozenberg, S., Lanoy, É., Bentata, M., Viard, J., Valantin, M., Missy, P., Darasteanu, I., Roux, C., Kolta, S., & Costagliola, D. G. (2012) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2011.0224 · Cited by 45 · see citing works
Evaluating cognitive impairment in the clinical setting: practical screening and assessment tools.
Valcour, V. (2011) · Europe PMC (PubMed Central) · Cited by 45 · see citing works
Bone health in HIV and hepatitis B or C infections
Biver, E., Calmy, A., & Rizzoli, R. (2016) · Therapeutic Advances in Musculoskeletal Disease · doi:10.1177/1759720x16671927 · Cited by 45 · see citing works
Frailty, markers of immune activation and oxidative stress in HIV infected elderly
Álvarez, S., Brañas, F., Sánchez‐Conde, M., Moreno, S., de Quirós, J. C. L. B., & Muñoz‐Fernández, M. Á. (2020) · PLoS ONE · doi:10.1371/journal.pone.0230339 · Cited by 45 · see citing works
Escota, G. V., Mondy, K. E., Bush, T. J., Conley, L. J., Brooks, J. T., Önen, N. F., Patel, P., Kojic, E. M., Henry, K., Hammer, J., et al. (2015) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2015.0158 · Cited by 43 · see citing works
HIV and Vertebral Fractures: a Systematic Review and Metanalysis
Ilha, T. A. S. H., Comim, F. V., Copês, R. M., Compston, J. E., & Premaor, M. O. (2018) · Scientific Reports · doi:10.1038/s41598-018-26312-9 · Cited by 44 · see citing works
Iribarren, S., Siegel, K., Hirshfield, S., Olender, S., Voss, J. G., Krongold, J., Luft, H., & Schnall, R. (2017) · AIDS and Behavior · doi:10.1007/s10461-017-1786-6 · Cited by 42 · see citing works
Focà, E., Motta, D., Borderi, M., Gotti, D., Albini, L., Calabresi, A., Izzo, I., Bellagamba, R., Narciso, P., Sighinolfi, L., et al. (2012) · BMC Infectious Diseases · doi:10.1186/1471-2334-12-38 · Cited by 41 · see citing works
Rentsch, C. T., Morford, K. L., Fiellin, D. A., BRYANT, K. J., Justice, A. C., & Tate, J. P. (2020) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14408 · Cited by 41 · see citing works
Self-citationSkeletal health in adults with HIV infection
Bolland, M. J., Grey, A. B., & Reid, I. R. (2014) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(13)70181-5 · Cited by 40 · see citing works
Güerri‐Fernández, R., Molina‐Morant, D., Villar-García, J., Prieto‐Alhambra, D., Mellibovsky, L., Nogués, X., González‐Mena, A., Guelar, A., Trenchs‐Rodríguez, M., Herrera, S., et al. (2016) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000000965 · Cited by 39 · see citing works
Levine, A. J., Sacktor, N. C., & Becker, J. T. (2020) · Journal of NeuroVirology · doi:10.1007/s13365-020-00897-2 · Cited by 38 · see citing works
Overall benefit of antiretroviral treatment on the risk of fracture in HIV
Mundy, L. M., Youk, A. O., McComsey, G. A., & Bowlin, S. J. (2012) · AIDS · doi:10.1097/qad.0b013e328351997f · Cited by 38 · see citing works
HIV infection and osteoporosis
Compston, J. E. (2015) · BoneKEy Reports · doi:10.1038/bonekey.2015.3 · Cited by 38 · see citing works
Classification of radiology reports for falls in an HIV study cohort
Bates, J., Fodeh, S. J., Brandt, C., & Womack, J. A. (2015) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocv155 · Cited by 38 · see citing works
Self-citationScreening for chronic comorbid diseases in people with HIV : the need for a strategic approach
Peters, B., Post, F. A., Wierzbicki, A. S., Phillips, A. N., Power, L., Das, S., Johnson, M. A., Moyle, G. J., Hughes, L., Wilkins, E., et al. (2012) · HIV Medicine · doi:10.1111/j.1468-1293.2012.01055.x · Cited by 37 · see citing works
Bone Health and Human Immunodeficiency Virus Infection
Schafer, J. J., Manlangit, K., & Squires, K. (2013) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1257 · Cited by 37 · see citing works
HIV, pathology and epigenetic age acceleration in different human tissues
Horvath, S., Lin, D. T. S., Kobor, M. S., Zoller, J. A., SAID, J. W., Morgello, S., Singer, E. J., Yong, W. H., Jamieson, B. D., & Levine, A. J. (2022) · GeroScience · doi:10.1007/s11357-022-00560-0 · Cited by 36 · see citing works
Peak Bone Mass in Young HIV-Infected Patients Compared With Healthy Controls
Negredo, E., Domingo, P., Ferrer, E., Estrada, V., Curran, A., Navarro, A., Isernia, V., Rosales, J., Pérez‐Álvarez, N., Puig, J., et al. (2013) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/01.qai.0000435598.20104.d6 · Cited by 35 · see citing works
Total Daily Pill Burden in HIV-Infected Patients in the Southern United States
Zhou, S., Martin, K. R., Corbett, A., Napravnik, S., Eron, J. J., Zhu, Y., Casciere, B., Boulton, C., Loy, B., Smith, S., et al. (2014) · AIDS Patient Care and STDs · doi:10.1089/apc.2014.0010 · Cited by 35 · see citing works
Prevalence of sub-clinical vertebral fractures in HIV-infected patients.
Borderi, M., Calza, L., Colangeli, Vanino, E., Viale, P., Gibellini, D., & Re, M. C. (2014) · PubMed · Cited by 35 · see citing works
Osteoporosis knowledge, self-efficacy, and health beliefs among Chinese individuals with HIV
Hsieh, E., Fraenkel, L., Bradley, E. H., Xia, W., Insogna, K. L., Qu, C., Li, K., & Li, T. (2014) · Archives of Osteoporosis · doi:10.1007/s11657-014-0201-4 · Cited by 35 · see citing works
Self-citationYang, J., Sharma, A., Shi, Q., Anastos, K., Cohen, M. H., Golub, E. T., Gustafson, D., Merenstein, D. J., Mack, W. J., Tien, P. C., et al. (2018) · AIDS · doi:10.1097/qad.0000000000001864 · Cited by 34 · see citing works
Self-citationA systematic review of psychosocial interventions for older adults living with HIV
Bhochhibhoya, A., Harrison, S. E., Yonce, S., Friedman, D. B., Ghimire, P. S., & Li, X. (2020) · AIDS Care · doi:10.1080/09540121.2020.1856319 · Cited by 31 · see citing works
Bone Health in HIV-Infected Children, Adolescents and Young Adults: A Systematic Review
Arpadi, S. M. (2014) · Journal of AIDS & Clinical Research · doi:10.4172/2155-6113.1000374 · Cited by 34 · see citing works
Tebas, P., Kumar, P. N., Hicks, C. B., Granier, C., Wynne, B., Min, S., & Pappa, K. A. (2015) · AIDS · doi:10.1097/qad.0000000000000863 · Cited by 33 · see citing works
HIV Infection and Osteoporosis: Pathophysiology, Diagnosis, and Treatment Options
Rothman, M. S., & Bessesen, M. T. (2012) · Current Osteoporosis Reports · doi:10.1007/s11914-012-0125-0 · Cited by 33 · see citing works
Abbondanzo, S. J., & Chang, S. L. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105256 · Cited by 33 · see citing works
Falls among Middle-Aged Women in the Women's Interagency HIV Study
Sharma, A., Hoover, D. R., Shi, Q., Holman, S., Plankey, M. W., Wheeler, A. L., Weber, K. M., Floris-Moore, M., Bolívar, H., Vance, D. E., et al. (2015) · Antiviral Therapy · doi:10.3851/imp3070 · Cited by 33 · see citing works
Self-citationEffects of sunlight exposure and vitamin D supplementation on HIV patients
Akimbekov, N. S., Ortoski, R. A., & Razzaque, M. S. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2020.105664 · Cited by 32 · see citing works
Osteoporosis and Fracture Risk Associated with HIV Infection and Treatment
Compston, J. E. (2014) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2014.05.001 · Cited by 32 · see citing works
Risk of hip fracture associated with untreated and treated chronic hepatitis B virus infection
Byrne, D. D., Newcomb, C. W., Carbonari, D. M., Nezamzadeh, M. S., Leidl, K. B. F., Herlim, M., Yang, Y.-X., Hennessy, S., Kostman, J. R., Leonard, M. B., et al. (2014) · Journal of Hepatology · doi:10.1016/j.jhep.2014.04.001 · Cited by 31 · see citing works
Mallon, P. W. G. (2014) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000080 · Cited by 31 · see citing works
Peters, B. S., Perry, M., Wierzbicki, A. S., Wolber, L. E., Blake, G. M., Patel, N., Hoile, R., Duncan, A., Kulasegaram, R., & Williams, F. M. K. (2013) · PLoS ONE · doi:10.1371/journal.pone.0078048 · Cited by 30 · see citing works
Hoy, J., & Young, B. (2016) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000249 · Cited by 29 · see citing works
Short, C.-E. S., Shaw, S. G., Fisher, M., Walker-Bone, K. E., & Gilleece, Y. C. (2013) · International Journal of STD & AIDS · doi:10.1177/0956462413492714 · Cited by 29 · see citing works
Kwan, C. K., Eckhardt, B. J., Baghdadi, J. D., & Aberg, J. A. (2012) · AIDS Research and Human Retroviruses · doi:10.1089/aid.2011.0325 · Cited by 29 · see citing works
Structural Bone Deficits in HIV/HCV-Coinfected, HCV-Monoinfected, and HIV-Monoinfected Women
Re, V. L., Lynn, K., Stumm, E. R., Long, J., Nezamzadeh, M. S., Baker, J. F., Hoofnagle, A. N., Kapalko, A., Mounzer, K., Zemel, B. S., et al. (2015) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiv147 · Cited by 28 · see citing works
Akgün, K. M., Tate, J. P., Oursler, K. K., Crystal, S., Leaf, D. A., Womack, J. A., Brown, T. T., Justice, A. C., & Crothers, K. A. (2016) · AIDS · doi:10.1097/qad.0000000000001162 · Cited by 28 · see citing works
Self-citationHepatitis C virus coinfection as a risk factor for osteoporosis and fracture
Bedimo, R. G., Maalouf, N. M., & Re, V. L. (2016) · Current Opinion in HIV and AIDS · doi:10.1097/coh.0000000000000259 · Cited by 27 · see citing works
Quirós-Roldán, E., Brianese, N., Raffetti, E., Focà, E., Pezzoli, M. C., Bonito, A., Ferraresi, A., Lanza, P., Porcelli, T., & Castelli, F. (2017) · The Brazilian Journal of Infectious Diseases · doi:10.1016/j.bjid.2017.08.003 · Cited by 26 · see citing works
Cournil, A., Eymard‐Duvernay, S., Diouf, A., Moquet, C., Coutherut, J., Gueye, N. F. N., Cames, C., Taverne, B., Bork, K., Sow, P. S., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0031726 · Cited by 26 · see citing works
Mary‐Krause, M., Viard, J., Ename-Mkoumazok, B., Bentata, M., Valantin, M., Missy, P., Darasteanu, I., Roux, C., Kolta, S., Costagliola, D. G., et al. (2012) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2012.04.001 · Cited by 26 · see citing works
- Authors
- Womack, J. A., Goulet, J. L., Gibert, C., Brandt, C., Chang, C. C., Gulanski, B., Fraenkel, L., Mattocks, K., Rimland, D., Rodriguez-Barradas, M. C., Tate, J., Yin, M. T., Justice, A. C., & for the Veterans Aging Cohort Study Project Team
- Affiliations
- VA Connecticut Healthcare System (US)
- George Washington University (US)
- Yale University (US)
- University of Pittsburgh (US)
- Emory University (US)
- Columbia University Irving Medical Center (US)
- Corresponding author
- Womack, Julie A.
- ORCID
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2011-02-16
- Volume
- 6
- Issue
- 2
- Pages
- e17217
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3040233
- OpenAlex
- W2155638837
- Cited by
- 261
- References
- 60
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 7 · 2023: 8 · 2022: 5 · 2021: 16 · 2020: 16 · 2019: 8 · 2018: 18 · 2017: 17 · 2016: 23 · 2015: 25 · 2014: 32 · 2013: 31 · 2012: 31
- FWCI
- 39.95
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, public-domain)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- D-Scholarship@Pitt (University of Pittsburgh) (acceptedVersion)
- The Journal of the American Medical Association (JAMA) Network (American Medical Association) (submittedVersion, public-domain)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Funders
- U.S. Department of Veterans Affairs
- National Institute on Alcohol Abuse and Alcoholism (U10AA013566, U10- AA13566)
- National Institute of Nursing Research (K01NR013437)
- National Institute of Allergy and Infectious Diseases (K23AI059884)
- Topics
- Health Sciences › Medicine › Emergency Medicine › HIV-related health complications and treatments
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Keywords
- HIV infection, fragility fractures, hip fracture, vertebral fractures, upper arm fractures, male veterans, body mass index, protease inhibitors, fracture risk factors, aging
- MeSH terms
- Aged, Aged, 80 and over, Follow-Up Studies, Humans, Male, Middle Aged, Osteoporosis, Risk Factors, Sex Characteristics, Veterans, HIV-1, Bone Density, HIV Infections, Fractures, Bone
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
