The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Specific Capture and Whole-Genome Sequencing of Viruses from Clinical Samples
Open accessAbstract
Whole genome sequencing of viruses directly from clinical samples is integral for understanding the genetics of host-virus interactions. Here, we report the use of sample sparing target enrichment (by hybridisation) for viral nucleic acid separation and deep-sequencing of herpesvirus genomes directly from a range of clinical samples including saliva, blood, virus vesicles, cerebrospinal fluid, and tumour cell lines. We demonstrate the effectiveness of the method by deep-sequencing 13 highly cell-associated human herpesvirus genomes and generating full length genome alignments at high read depth. Moreover, we show the specificity of the method enables the study of viral population structures and their diversity within a range of clinical samples types.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
BLAST+: architecture and applications
Camacho, C., Coulouris, G., Avagyan, V., Ma, N., Papadopoulos, J., Bealer, K., & Madden, T. L. (2009) · BMC Bioinformatics · doi:10.1186/1471-2105-10-421 · Cited by 22,074
Gnirke, A., Melnikov, A., Maguire, J., Rogov, P., LeProust, E. M., Brockman, W., Fennell, T., Giannoukos, G., Fisher, S., Russ, C., et al. (2009) · Nature Biotechnology · doi:10.1038/nbt.1523 · Cited by 1,433
Self-citationVignuzzi, M., Stone, J. K., Arnold, J. J., Cameron, C. E., & Andino, R. (2006) · Nature · doi:10.1038/nature04388 · Cited by 1,116
Kew, O., Morris-Glasgow, V., Landaverde, M., Burns, C., Shaw, J., Garib, Z., André, J., Blackman, E., Freeman, C. J., Jorba, J., et al. (2002) · Science · doi:10.1126/science.1068284 · Cited by 600
Cited by
Large-scale de novo DNA synthesis: technologies and applications
Kosuri, S., & Church, G. M. (2014) · Nature Methods · doi:10.1038/nmeth.2918 · Cited by 869
Clinical and biological insights from viral genome sequencing
Houldcroft, C. J., Beale, M. A., & Breuer, J. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2016.182 · Cited by 334
Self-citationEnhanced virome sequencing using targeted sequence capture
Wylie, T. N., Wylie, K. M., Herter, B. N., & Storch, G. A. (2015) · Genome Research · doi:10.1101/gr.191049.115 · Cited by 263
Next-Generation Sequencing for Infectious Disease Diagnosis and Management
Lefterova, M. I., Suarez, C. J., Banaei, N., & Pinsky, B. A. (2015) · The Journal of Molecular Diagnostics · doi:10.1016/j.jmoldx.2015.07.004 · Cited by 207
Metadata
- Authors
- Depledge, D. P., Palser, A. L., Watson, S. J., Lai, I. Y.-C., Gray, E. R., Grant, P., Kanda, R. K., Leproust, E., Kellam, P., & Breuer, J.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2011-11-18
- Volume
- 6
- Issue
- 11
- Pages
- e27805
- ISSN
- 1932-6203 (ISSN-L)
- OpenAlex
- W2094212509
- Cited by
- 229
- References
- 4
- FWCI
- 2.94
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Specific Capture and Whole-Genome Sequencing of Viruses from Clinical Samples. https://app.cochat.ai/papers/10.1371/journal.pone.0027805
- The paper
- Depledge, D. P., Palser, A. L., Watson, S. J., Lai, I. Y.-C., Gray, E. R., Grant, P., Kanda, R. K., Leproust, E., Kellam, P., & Breuer, J. (2011). Specific Capture and Whole-Genome Sequencing of Viruses from Clinical Samples. PLoS ONE. https://doi.org/10.1371/journal.pone.0027805
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.