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A RCT of a Transdiagnostic Internet-Delivered Treatment for Three Anxiety Disorders: Examination of Support Roles and Disorder-Specific Outcomes
Open accessAbstract
BACKGROUND: Anxiety disorders share common vulnerabilities and symptoms. Disorder-specific treatment is efficacious, but few access evidence-based care. Administering transdiagnostic cognitive-behavioral therapy via the internet (iCBT) may increase access to evidence-based treatment, with a recent randomized controlled trial (RCT) providing preliminary support for this approach. This study extends those findings and aims to answer three questions: Is a transdiagnostic iCBT program for anxiety disorders efficacious and acceptable? Does it result in change for specific disorders? Can good clinical outcomes be obtained when guidance is provided via a Coach rather than a Clinician? METHOD: RCT (N = 131) comparing three groups: Clinician-supported (CL) vs. Coach-supported (CO) vs. waitlist control (Control). Individuals met DSM-IV criteria for a principal diagnosis of generalized anxiety disorder (GAD), social phobia (SP) or panic disorder with or without agoraphobia (Pan/Ag). Treatment consisted of an 8-lesson/10 week iCBT program with weekly contact from a Clinician or Coach, and follow-up at 3-months post-treatment. RESULTS: Outcomes for the pooled treatment groups (CL+CO) were superior to the Control group on measures of anxiety, depression and disability, were associated with medium to large effect sizes (Cohen's d = .76-1.44) (response rate = 89-100%), and were maintained at follow-up. Significant reductions were found on disorder-specific outcomes for each of the target diagnoses, and were associated with large effect sizes. CO participants achieved similar outcomes to CL participants at post-treatment, yet had significantly lower symptom severity scores on general anxiety, panic-disorder, depression and disability at follow-up (d = .45-.46). Seventy-four percent of CO and 76% of CL participants completed the program. Less than 70 minutes of Clinician or Coach time was required per participant during the program. DISCUSSION: This transdiagnostic iCBT course for anxiety appears to be efficacious, associated with significant change for three target disorders, and is efficacious when guided by either a Clinician or Coach. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry ACTRN12610000242022.
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“Previous studies have not found significant differences in acceptability or outcomes when support is offered by either graduate student practitioners or registered healthcare professionals (e.g. Johnston et al., 2011).”
From Five-year observational study of Internet-delivered cognitive behavioural pain management when offered as routine care by an online therapy clinic (2022) · cites this paper as Johnston et al., 2011
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“In randomised controlled trials (RCTs) TD-CBT has been shown to be more effective compared to waitlist control (WLC) in group-format (controlled between-group ES: d = .50)(Erickson, Janeck, & Tallman, 2007) and online delivery (Johnston et al., 2011).”
From Systematic review and meta-analysis of transdiagnostic psychological treatments for anxiety and depressive disorders in adulthood (2015) · cites this paper as Johnston et al., 2011
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Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7
Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765 · cited 2×
“The Generalized Anxiety Disorder 7-Item Scale, (GAD-7) [26] and Depression Anxiety Stress Scales – 21 Item (DASS-21) [27] were used as primary outcome measures.”
Method(1998) · The Journal of Clinical Psychiatry · Cited by 19,139
(1998) · PubMed · Cited by 10,216
(1995) · Cited by 6,909
The mini international neuropsychiatric interview
Lecrubier, Y., Sheehan, D. V., Hergueta, T., & Weiller, E. (1998) · European Psychiatry · doi:10.1016/s0924-9338(99)80239-9 · Cited by 5,899
Development and validation of the Penn State Worry Questionnaire
Meyer, T. J., Miller, M. L., Metzger, R. L., & Borkovec, T. D. (1990) · Behaviour Research and Therapy · doi:10.1016/0005-7967(90)90135-6 · Cited by 5,099 · cited 3×
“Penn State Worry Questionnaire (PSWQ) [28].”
BackgroundMethodAntony, M. M., Bieling, P. J., Cox, B. J., Enns, M. W., & Swinson, R. P. (1998) · Psychological Assessment · doi:10.1037/1040-3590.10.2.176 · Cited by 4,874 · cited 1×
“The 21-item short form has demonstrated excellent psychometric properties including good internal consistency and concurrent validity comparable with the original 42-item measure [36].”
MethodLöwe, B., Decker, O., Müller, S., Brähler, E., Schellberg, D., Herzog, W., & Herzberg, P. Y. (2008) · Medical Care · doi:10.1097/mlr.0b013e318160d093 · Cited by 4,527 · cited 2×
“This was defined as the proportion of participants who initially scored at or above, and subsequently scored below the cut-offs of a GAD-7 total score $8 [34].”
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2 of the 62 references couldn’t be matched to a known paper.
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- R Mattick, 1998, Development and validation of measures of social phobia scrutiny fear and social interaction anxiety., Behaviour Research and Therapy, 36, 455
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Items 101–150 of 150
Bernstein, E. E., Greenberg, J. L., Weingarden, H. M., Snorrason, Í., Summers, B. J., Williams, J., Quist, R. E., Curtiss, J. E., Harrison, O., & Wilhelm, S. (2024) · Internet Interventions · doi:10.1016/j.invent.2024.100743 · Cited by 7
“In fact, reviews of internet-based interventions show that coaches' qualifications (i.e., professional versus non-professional) are poor predictors of outcomes (Baumeister et al., 2014; Johnston et al., 2021).”
BackgroundKornfield, R., Lattie, E. G., Nicholas, J., Knapp, A. A., Mohr, D. C., & Reddy, M. C. (2023) · Proceedings of the ACM on Human-Computer Interaction · doi:10.1145/3610093 · Cited by 7
“Fortunately, evidence indicates that coaching still has benefits for users when coaches lack professional mental health expertise [5,6,40,109].”
BackgroundKladnistki, N., Black, M., Haffar, S., Joubert, A., & Newby, J. M. (2022) · Clinical Psychologist · doi:10.1080/13284207.2022.2057217 · Cited by 5
Internet-Delivered Psychotherapy for Anxiety Disorders and Depression
Titov, N., Dear, B. F., & Andersson, G. (2014) · Focus · doi:10.1176/appi.focus.12.3.299 · Cited by 5
Self-citationDahlin, M. (2020) · Linköping studies in behavioural science · doi:10.3384/diss.diva-170049 · Cited by 5
Cognitive‐Behaviour Therapy and Psychological Treatments in Australia
Moulding, R., Nedeljkovic, M., & King, R. M. (2020) · Australian Psychologist · doi:10.1111/ap.12358 · Cited by 6
Lu, S. H., Assudani, H. A., Kwek, T. R. R., Ng, S. W. H., Teoh, T. E. L., & Tan, G. C.-Y. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.668384 · Cited by 5
“, 2010) or for comorbid depression and anxiety (Titov et al., 2010, 2011, 2012; Dear et al., 2011; Johnston et al., 2011).”
BackgroundTransdiagnostic CBT versus counselling sessions: a naturalistic trial from Saudi Arabia
Alatiq, Y. (2021) · The Cognitive Behaviour Therapist · doi:10.1017/s1754470x20000628 · Cited by 4
“It is not yet clear which format is best, but randomized control trials have shown that group T-CBT (Erickson et al., 2007) and online T-CBT (Johnston et al., 2011) are more effective than waitlist control.”
BackgroundWahle, F., & Kowatsch, T. (2014) · Journal of the Association for Information Systems · Cited by 4
Rubel, J. A., Quest, J., Pruessner, L., Timm, C., Hartmann, S. F., Barnow, S., Rittmeyer, L., Rosenbaum, D., & Lalk, C. (2022) · Internet Interventions · doi:10.1016/j.invent.2022.100584 · Cited by 4
“Additionally, neither frequency of a supportive attendant (Klein et al., 2009; Oromendia et al., 2016) nor the experience or training of the support person (Johnston et al., 2011) seem to have a significant influence on panic disorder symptom reduction.”
Cho, I., Kim, B.-H., Lee, H., Song, Y., Chang, M. J., Kim, J., & Han, E. (2025) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2025.103074 · Cited by 3
İngeç, Ö. E., & Yorulmaz, O. (2021) · Psikiyatride Guncel Yaklasimlar - Current Approaches in Psychiatry · doi:10.18863/pgy.768731 · Cited by 3
Internet-Delivered Cognitive Behavioral Therapy for Anxiety
Onyeka, O. “., Riddle, D., Bivins, E. J., Armstrong, G. M., Upshaw, B. M., Rast, C. E., & Silva, T. (2024) · Advances in Psychiatry and Behavioral Health · doi:10.1016/j.ypsc.2024.05.003 · Cited by 8
Miciuk, Ł. R. (2020) · Wydawnictwo Liberi Libri eBooks · doi:10.47943/lib.9788363487430.rozdzial20 · Cited by 3
Guided Internet Treatment of Anxiety Disorders in Adults
Andersson, G. (2014) · Wiley eBooks · doi:10.1002/9781118775349.ch61 · Cited by 3
Brunner, I. C., Støme, L. N., & Kenter, R. M. F. (2026) · Internet Interventions · doi:10.1016/j.invent.2026.100983 · Cited by 2
“From an implementation science perspective, an important source of DMHI-specific workload relates to workflow integration, platform usability, and interoperability with existing health information systems (Titov et al., 2019).”
InfluentialLalk, C., Väth, T., Hanraths, S., Pruessner, L., Timm, C., Hartmann, S. F., Barnow, S., & Rubel, J. A. (2025) · Journal of Medical Internet Research · doi:10.2196/54062 · Cited by 4
The Use of Technology to Augment Clinical Care in Depression and Anxiety Disorders: An Evidence Map
Maher, A. R., Apaydin, E. A., Raaen, L. B., Motala, A., Shanman, R., & Hempel, S. (2019) · RAND Corporation eBooks · doi:10.7249/rr2177 · Cited by 2
“…2016; Johansson, Björkland, et al., 2013; Johansson, 11 Ekbladh, et al., 2012; Johansson, Lyssarides, et al., 2013; Johansson, Sjöberg, et al., 2012; Johnston et al., 2011; Jonas, Leuschner, and Tossmann, 2016; Jonassaint et al., 2017; Jones, Hadjistavropoulos, and Soucy, 2016; Kafali et al.,…”
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2021) · medRxiv · doi:10.1101/2021.04.12.21255333 · Cited by 2
Lalk, C., Väth, T., Hanraths, S., Pruessner, L., Timm, C., Hartmann, S. F., Barnow, S., & Rubel, J. A. (2023) · doi:10.31234/osf.io/w9f4s · Cited by 2
Pugh, N. E. (2014) · oURspace (University of Regina) · doi:10.82465/5755 · Cited by 2
A meta-analysis of the effectiveness of internet-based cognitive-behavioral therapy on social phobia
Ahangari, N., Bakhtiari, M., & Katani, A. M. (2022) · Medical Science · doi:10.54905/disssi/v26i128/ms414e2314 · Cited by 2
The Importance of Case Conceptualization and Therapeutic Alliance
Ornelas, A. C., & da Silva, M. M. (2024) · Springer eBooks · doi:10.1007/978-3-031-63494-9_3 · Cited by 1
Prior, K., Baillie, A., Newton, N. C., Lee, Y. Y., Deady, M., Gückel, T., Wade, L., Rapee, R. M., Hudson, J. L., KAY‐LAMBKIN, F. J., et al. (2024) · Addiction · doi:10.1111/add.16522 · Cited by 1
Toro, R., Gómez, L. J. G., Mancipe, Á. P. S., Aguirre, K. V. B., Parra, K. R., & Ortíz, L. M. G. (2015) · Enfoques · doi:10.24267/23898798.202 · Cited by 1
Ulatowska, J. (2020) · Wydawnictwo Liberi Libri eBooks · doi:10.47943/lib.9788363487430.rozdzial18 · Cited by 21
Friesen, L. N. (2015) · oURspace (University of Regina) · doi:10.82465/6970 · Cited by 1
Johansson, T., & Sjögren, J. (2012)
Fritzges, J. L. (2015) · ScholarWorks (Walden University)
Cláudia, A., Braga, A. D. A., Nunes, C. A., & Silva, A. C. (2013)
The progression and management of depression and anxiety in chronic hepatitis C patients.
Stewart, B. J. (2015) · Adelaide Research & Scholarship (AR&S) (University of Adelaide)
Robles, V. A. G. (2019) · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya) · doi:10.6035/14109.2019.233592
Nowoczesne metody wykorzystujące ruch w terapii ruchowej, poznawczej oraz w edukacji
Sobolewska, N., & Gut, M. (2020) · Wydawnictwo Liberi Libri eBooks · doi:10.47943/lib.9788363487430.rozdzial06
Metody badania długości, przebiegu i jakości snu używane w psychologii sportu
Szeremeta, E., & Trojan, M. (2020) · Wydawnictwo Liberi Libri eBooks · doi:10.47943/lib.9788363487430.rozdzial05
„Schreib’ ich da eigentlich wirklich mit jemandem…?“
Speer, D., & Prokop, A. (2021) · Perspektiven Sozialwirtschaft und Sozialmanagement · doi:10.1007/978-3-658-32556-5_13
Romijn, G., Batelaan, N. M., Kok, R., Koning, J., van Balkom, A. J. L. M., Titov, N., & Riper, H. M. (2018) · doi:10.2196/preprints.11706
Self-citationThe Unified Protocol Approach for Emotional Disorders
Ornelas, A. C., & da Silva, M. M. (2024) · Springer eBooks · doi:10.1007/978-3-031-63494-9_11
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22767515
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22767530
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22767518
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22767521
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22767527
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22767524
Sasseville, M., LeBlanc, A., Tchuente, J., Boucher, M., Dugas, M., Mbemba, G. I. C., Barony, R., Chouinard, M., Beaulieu, M., Beaudet, N., et al. (2023) · Figshare · doi:10.6084/m9.figshare.22767512
Internet CBT for panic disorder - a review
Praško, J., Vaněk, J., Bělohradová, K., Sollár, T., Šlepecký, M., Mikula, M., & Ocisková, M. (2026) · Psychiatrie pro praxi · doi:10.36290/psy.2026.021
Palmili, L. (2013) · UPT. Syiah Kuala University Library (Syiah Kuala University)
Metadata
- Authors
- Johnston, L., Titov, N., Andrews, G., Spence, J., & Dear, B. F.
- Affiliations
- UNSW Sydney (AU)
- Macquarie University (AU)
- Corresponding author
- Johnston, Luke
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2011-11-23
- Volume
- 6
- Issue
- 11
- Pages
- e28079
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3223218
- OpenAlex
- W2006280171
- Cited by
- 150
- References
- 62
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 10 · 2023: 11 · 2022: 9 · 2021: 9 · 2020: 12 · 2019: 6 · 2018: 11 · 2017: 7 · 2016: 15 · 2015: 13 · 2014: 18 · 2013: 15 · 2012: 6
- FWCI
- 16.59
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Figshare (submittedVersion, cc-by)
- Funders
- New South Wales Institute of Psychiatry
- Australian Rotary Health
- University of New South Wales
- Medical Research Council
- National Health and Medical Research Council
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- transdiagnostic cognitive behavioral therapy, internet-delivered treatment, anxiety disorders, generalized anxiety disorder, social anxiety disorder, panic disorder, agoraphobia, treatment acceptability, treatment efficacy, depression, disability
- MeSH terms
- Adult, Anxiety Disorders, Demography, Female, Humans, Male, Patient Compliance, Social Support, Comorbidity, Cognitive Behavioral Therapy, Case-Control Studies, Treatment Outcome, Internet
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