An obligate role of oxytocin neurons in diet induced energy expenditure
Wu, Zhaofei, Xu, Yuanzhong, Zhu, Yaming, Sutton, Amy K., Zhao, Rongjie, Lowell, Bradford B., Olson, David P., Tong, Qingchun·2012·PLoS ONE
Cited by (181)
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- Systemic Co-Administration of Low-Dose Oxytocin and Glucagon-Like Peptide 1 Additively Decreases Food Intake and Body WeightYuko Maejima, Shoko Yokota, Shizu Hidema, Katsuhiko Nishimori, Heidi de Wet, Kenju Shimomura · 2024 · Neuroendocrinology
- Glutamatergic melanocortin‐4 receptor neurons regulate body weightHaodong Liu, Xiaojing Li, Penghui Li, Rihan Hai, Jiacheng Li, Qi Fan, Xing Wang, Yujie Chen, Xiaojuan Cao, Xiaoyu Zhang et al. · 2023 · The FASEB Journal
- OXTR DNA methylation differentiates men on the obesity spectrum with and without binge eating disorderKatrin Elisabeth Giel, Kathrin Schag, Elisabeth Johanna Leehr, Isabelle Mack, Lea-Sarah Schuster, Ariane Wiegand, Stephan Zipfel, Manfred Hallschmid, Vanessa Nieratschker · 2022 · Clinical Epigenetics
- Oxytocin induces embryonic diapauseJessica L. Minder, Sarah B. Winokur, Janaye Stephens, Jie Tong, Naomi L. Cassel, Luisa Schuster, Habon A. Issa, Michael Cammer, Latika Khatri, Gaia Moisan et al. · 2025 · Science Advances
- Oxytocin neurons in the paraventricular and supraoptic hypothalamic nuclei bidirectionally modulate food intakeJessica J. Rea, Clarissa M. Liu, Anna Hayes, Rita Ohan, Grace M. Schwartz, Alexander G. Bashaw, Molly E. Klug, Léa Décarie-Spain, Yedam Park, Alicia E. Kao et al. · 2025 · Molecular Metabolism
- Neuroendocrine Control of Body Energy HomeostasisAlison H. Affinati, Martin Grosvenor Myers · 2021 · Europe PMC (PubMed Central)
- Do oxytocin neurones affect feeding?Amy A. Worth, Simon M. Luckman · 2021 · Journal of Neuroendocrinology
- Energy Expenditure Homeostasis Requires ErbB4, an Obesity Risk Gene, in the Paraventricular NucleusIván G. Santiago-Marrero, Fang Liu, Hongsheng Wang, Emily P. Arzola, Wen‐Cheng Xiong, Lin Mei · 2023 · eNeuro
- Orthopedia regulates melanocortin 4 receptor transcription and energy homeostasisBaijie Xu, Katherine Lawler, Steven C. Wyler, Li Li, SWATI SWATI, Julia M. Keogh, Xiameng Chen, Rong Wan, Amanda G. Almeida, Susan E. Kirsch et al. · 2025 · Science Translational Medicine
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- Negative feedback regulation of alcohol ingestion through the FGF21-PVH oxytocin-VTA dopamine systemSho Matsui, Yuma Takahashi, Shuhei Morioka, Takaaki Ozawa, Sachiho Kanayama, Hiroki Iwama, Lan Geng, Kazuhiro Umemoto, Yasuo Oguri, Satoshi Tsuzuki et al. · 2026 · Proceedings of the National Academy of Sciences
- The Role of Central Oxytocin in Autonomic RegulationSheng‐Feng Tsai, Yu‐Min Kuo · 2024 · Journal of physiological investigation.
- Sympathetic Innervation of Interscapular Brown Adipose Tissue Is Not a Predominant Mediator of Oxytocin-Induced Brown Adipose Tissue Thermogenesis in Female High Fat Diet-Fed RatsAndrew Dale Dodson, Adam Jay Herbertson, Mackenzie K. Honeycutt, Ron Vered, Jared D. Slattery, Matvey Goldberg, Edison W. Tsui, Tami Wolden‐Hanson, James Lawrence Graham, Tomasz Wietecha et al. · 2024 · Current Issues in Molecular Biology
- Sympathetic innervation of interscapular brown adipose tissue is not a predominant mediator of Oxytocin (OT)-elicited reductions of body weight gain and adiposity in male diet-induced obese ratsMélise Marie Edwards, Ha K. Nguyen, Andrew Dale Dodson, Adam Jay Herbertson, Mackenzie K. Honeycutt, Jared D. Slattery, June R. Rambousek, Edison W. Tsui, Tami Wolden‐Hanson, Tomasz Wietecha et al. · 2024 · Frontiers in Drug Delivery
- Paraventricular oxytocin neurons impact energy intake and expenditure: projections to the bed nucleus of the stria terminalis reduce sucrose consumptionAmy A. Worth, Claire H. Feetham, Nicole A. Morrissey, Simon M. Luckman · 2024 · Frontiers in Endocrinology
- Intestinal Electrical Stimulation Alters Hypothalamic Expression of Oxytocin and Orexin and Ameliorates Diet-Induced Obesity in RatsShiying Li, Yeram Kim, Jiande D. Z. Chen, Mohammad F. Madhoun · 2021 · Obesity Surgery
- Increased neuronal activation in sympathoregulatory regions of the brain and spinal cord in type 2 diabetic ratsShivani Sethi, Rachael A. Augustine, Gregory T. Bouwer, Michael R. Perkinson, Isaiah Cheong, Carol T. Bussey, Daryl O. Schwenke, Colin H. Brown, Regis R. Lamberts · 2021 · Journal of Neuroendocrinology
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- Disruption of CRTC1 and CRTC2 in Sim1 cells strongly increases high-fat diet intake in female mice but has a modest impact on male miceJin Tanaka, Fuka Ishikawa, Tomoki Jinno, Motoki Miyakita, Haruka Miyamori, Tsutomu Sasaki, Takumi Yokokawa, Tsuyoshi Goto, Kazuo Inoue, Shigenobu Matsumura · 2022 · PLoS ONE
- Functional and Anatomical Dissection of Feeding CircuitsDeniz Atasoy, Scott M. Sternson · 2016 · Wiley eBooks
- Oxytocin neurons signal state-dependent transitions from rest to thermogenesis and behavioral arousalMorgane Vandendoren, Jason G Landen, Joseph F Rogers, Samantha Killmer, Baizar Alamiri, Celeste Pohlman, Glenn J. Tattersall, Nicole L. Bedford, Adam C. Nelson · 2026 · eLife
- Hunger Games: A Modern Battle Between Stress and AppetiteWhitnei Smith, Estefania P. Azevedo · 2025 · Journal of Neurochemistry
- Promotion of obesity by fibroblast growth factor 21-oxytocin system dysfunction due to sugar-specific hyperphagiaHajime Mori, Kanako Inoue, Sho Matsui, Yasuo Oguri, Satoshi Tsuzuki, Tsutomu Sasaki · 2025 · American Journal of Physiology-Endocrinology and Metabolism
- Three‐dimensional quantification of oxytocin neurons in the hypothalamic paraventricular nucleus reveals sex‐ and subregion‐specific differences in two genetic mouse models of autismAishwarya Patwardhan, Siyao Li, Jessica A. Chen, Katrina Y. Choe · 2025 · Journal of Neuroendocrinology
- Region and Cell‐Selective Induction of Zbtb16/Plzf by Multiple Stressors in the Adult Murine HypothalamusMina Roueinfar, Pardis Mohammadzadeh, Luke Schwerdtfeger, Robert J. Handa, Stuart A. Tobet · 2026 · European Journal of Neuroscience
- L’hypophyse et ses traitements : comment peuvent-ils influer sur le comportement ?Céline Mouly, Françoise Borson‐Chazot, Philippe Jean Caron · 2017 · Annales d Endocrinologie
- Intranasal oxytocin administration rescues neonatal thermo-sensory deficit in mouse model of AutismLaura Caccialupi Da Prato, Dina Abdallah, Vanessa Point, Fabienne Schaller, Emilie Pallesi‐Pocachard, Aurélie Montheil, Stéphane Canaan, Jean‐Luc Gaïarsa, Françoise Muscatelli, Valery A. Matarazzo · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
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- Oxytocin Effects on Food Stimulus Processing and Food Intake in Females With or Without Binge Eating DisorderJulia Nannt, Mechteld M. van den Hoek Ostende, Brunna Tuschen‐Caffier, Markus Heinrichs, Daniel Sippel, Manfred Hallschmid, Jennifer Svaldi · 2025 · International Journal of Eating Disorders
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- Peripheral cholecystokinin promotes thermogenesis via vagal afferent signalling, hypothalamic oxytocin and sympathetic outflow to brown adipose tissueYuta Masuda, Miyuki Kawase, Rika Kitano, Kento Ohbayashi, Toshiki Yabe‐Wada, Hiroshi Inoue, Mamoru Tanida, Yusaku Iwasaki · 2026 · The Journal of Physiology
- Oxytocin as a Metabolic ModulatorNeeru Bhatt · 2021 · IntechOpen eBooks
- Oxytocin: Potential New Treatment for Binge EatingYoul‐Ri Kim, Soo Min Hong, Jung‐Joon Moon · 2020 · Springer eBooks
- Remodeling of purinergic signaling in the paraventricular hypothalamus promotes hyperphagic obesity and insulin resistanceYu Liu, Anastasiia Bondarenko, Haiyang Zhang, Pengwei Luan, Qian Zhang, Bo Wang, Syeda Sadia Najam, Xian Liang, Ali Alamdar Shah Syed, Dongfa Lin et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The Effect of Stage of Lactation on the Response of Postpartum Rats to the Administration of Anorectic and Orexigenic PeptidesRadek Budin · 2016 · Spectrum Research Repository (Concordia University)
- Faculty Opinions recommendation of The paraventricular hypothalamus regulates satiety and prevents obesity via two genetically distinct circuits.Robert J. Handa, Ashley Heck · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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