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Cited by 283

The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.

Toxicity Assessment of Iron Oxide Nanoparticles in Zebrafish (Danio rerio) Early Life Stages

Open access
Zhu, Xiaoshan, Tian, Shengyan, Cai, Zhonghua·2012·PLoS ONE

Abstract

Iron oxide nanoparticles have been explored recently for their beneficial applications in many biomedical areas, in environmental remediation, and in various industrial applications. However, potential risks have also been identified with the release of nanoparticles into the environment. To study the ecological effects of iron oxide nanoparticles on aquatic organisms, we used early life stages of the zebrafish (Danio rerio) to examine such effects on embryonic development in this species. The results showed that ≥10 mg/L of iron oxide nanoparticles instigated developmental toxicity in these embryos, causing mortality, hatching delay, and malformation. Moreover, an early life stage test using zebrafish embryos/larvae is also discussed and recommended in this study as an effective protocol for assessing the potential toxicity of nanoparticles. This study is one of the first on developmental toxicity in fish caused by iron oxide nanoparticles in aquatic environments. The results will contribute to the current understanding of the potential ecotoxicological effects of nanoparticles and support the sustainable development of nanotechnology.

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Metadata

Authors
Zhu, X., Tian, S., & Cai, Z.
Venue
PLoS ONE
Published
2012-09-27
Volume
7
Issue
9
Pages
e46286
ISSN
1932-6203 (ISSN-L)
OpenAlex
W2000868408
Cited by
283
References
53
FWCI
11.59
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Toxicity Assessment of Iron Oxide Nanoparticles in Zebrafish (Danio rerio) Early Life Stages. https://app.cochat.ai/papers/10.1371/journal.pone.0046286
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Zhu, X., Tian, S., & Cai, Z. (2012). Toxicity Assessment of Iron Oxide Nanoparticles in Zebrafish (Danio rerio) Early Life Stages. PLoS ONE. https://doi.org/10.1371/journal.pone.0046286

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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