Cited by 309Fungal Infections and StudiesBacterial Infections and VaccinesParasitic Infections and Diagnostics

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Epidemiology of Cryptococcal Meningitis in the US: 1997–2009

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Pyrgos, Vasilios, Seitz, Amy E., Steiner, Claudia A., Prevots, D. Rebecca, Williamson, Peter R.·2013·PLoS ONE

DOI 10.1371/journal.pone.0056269PMC PMC3574138

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Abstract

Cryptococcal meningitis (CM) causes significant morbidity and mortality globally; however, recent national trends have not been described. Incidence and trends for CM-associated hospitalizations in 18 states were estimated using the Agency for Healthcare and Research Quality (AHRQ) State Inpatient Databases (SID) datasets for 1997 through 2009. We identified 30,840 hospitalizations coded for CM, of which 21.6% were among HIV-uninfected patients. CM in-hospital mortality was significant (12.4% for women and 10.8% for men) with a total of 3,440 deaths over the study period. Co-morbidities of CM coded at increased frequency in HIV-uninfected CM hospitalized populations included hydrocephalus and acute/chronic renal failure as well as possible predispositions including transplantation, combined T and B cell defects, Cushing's syndrome, liver disease and hypogammaglobulinemia. Median hospitalization costs were significant for CM and higher for HIV-uninfected patients (16,803.01 vs. 15,708.07; p<0.0001). Cryptococcal meningitis remains a disease with significant morbidity and mortality in the U.S. and the relative burden among persons without HIV infection is increasing.

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Clinical Practice Guidelines for the Management Candidiasis: 2009 Update by the Infectious Diseases Society of America
Pappas, P. G., Kauffman, C. A., Andes, D., Benjamin, D. K., Calandra, T. F., Edwards, J. E., Filler, S. G., Fisher, J. F., Kullberg, B.-J., Zeichner, L. O., et al. (2009) · Clinical Infectious Diseases · doi:10.1086/596757 · Cited by 3,191
Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America
Perfect, J. R., Dismukes, W. E., Dromer, F., Goldman, D. L., Graybill, J. R., Hamill, R. J., Harrison, T. S., Larsen, R. A., Lortholary, O., Nguyen, M.-H., et al. (2010) · Clinical Infectious Diseases · doi:10.1086/649858 · Cited by 2,660
Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
Park, B. J., Wannemuehler, K. A., Marston, B. J., Govender, N. P., Pappas, P. G., & Chiller, T. M. (2009) · AIDS · doi:10.1097/qad.0b013e328322ffac · Cited by 2,062
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Walsh, T. J., Finberg, R. W., Arndt, C., Hiemenz, J., Schwartz, C., Bodensteiner, D., Pappas, P., Seibel, N., Greenberg, R. N., Dummer, S., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199903113401004 · Cited by 1,205
Prevalence of Nontuberculous Mycobacterial Lung Disease in U.S. Medicare Beneficiaries
Adjemian, J., Olivier, K. N., Seitz, A. E., Holland, S. M., & Prevots, D. R. (2012) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201111-2016oc · Cited by 691
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Mirza, S. A., Phelan, M., Rimland, D., Graviss, E. A., Hamill, R. J., Brandt, M. E., Gardner, T. J., Sattah, M., de León, G. P., Baughman, W. S., et al. (2003) · Clinical Infectious Diseases · doi:10.1086/368091 · Cited by 455

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Computational vaccinology approach: Designing an efficient multi-epitope peptide vaccine against Cryptococcus neoformans var. grubii’s heat shock 70KDa proteinPreprint
Elhassan, R. M., Alsony, N. M., Othman, K. M., Izz-Aldin, D. T., Alhaj, T. A., Ali, A. A., Abashir, L. A., Ahmed, O. H., & Hassan, M. A. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/534008 · Cited by 5
Immunophenotyping of apparently immunocompetent hosts with cryptococcosis reveals IL-17 deficiency as a unifying susceptibility factor
Townsend, K., Kannambath, S., Hayman, G., Döffinger, R., Ceron‐Gutierrez, L., Ebrahimi, S., Pavlova, V., Gothard, P., Brown, M., Tahami, F., et al. (2025) · Clinical & Experimental Immunology · doi:10.1093/cei/uxaf053 · Cited by 4
Disseminated Cryptococcus infection presenting as lytic skeletal lesions suggesting bony metastatic disease
Yeung, C. M., & Fabbri, N. (2023) · Skeletal Radiology · doi:10.1007/s00256-023-04442-0 · Cited by 4
Effects of human immunoglobulin A on Cryptococcus neoformans morphology and gene expression
Trevijano‐Contador, N., de Oliveira, H. C., Malacatus-Bravo, C., Sarai, V., Cuesta, I., Rodrigues, M. L., Zaragoza, Ó., & Pirofski, L. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.02008-24 · Cited by 4
Rapid Fatal Outcome of Cryptococcal Meningoencephalitis in a Non-HIV Immunocompromised Patient with a Low Fluconazole Susceptibility Isolate: A Case Report from Madagascar
Raberahona, M., Rakotoarivelo, R. A., Randriamampionona, N., Rakotomalala, F. A., Razafinambinintsoa, T., Bénet, T., Vanhems, P., Randria, M. J. D. D., Cornet, M., & Andrianarivelo, M. R. (2016) · Case Reports in Infectious Diseases · doi:10.1155/2016/3492504 · Cited by 4
Meningitis criptocóccica en pacientes sin infección por VIH: presentación de dos casos y revisión de la literatura
Ramirez-Ramos, C. F., Galindo, J. D., Correa, S., Giraldo-Bahamón, G., Rivera, J. D. V., Solano, J., Peralta, M. D. M., & González-Manrique, G. (2018) · Revista chilena de infectología · doi:10.4067/s0716-10182018000600716 · Cited by 4
Carbonic anhydrases from pathogens
Bonardi, A., Gratteri, P., & Nocentini, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816476-1.00019-8 · Cited by 5
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Saullo, J. H., & Alexander, B. D. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-3383-5.00038-5 · Cited by 5
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Sayhi, S., Bouzidi, S., Beji, I., Nasr, A. A., Hannachi, S., Bedoui, I., Layouni, S., Fekih‐Mrissa, N., Louzir, B., Nsiri, B., et al. (2020) · Pan African Medical Journal · doi:10.11604/pamj.2020.36.324.20407 · Cited by 4
A case of HIV negative cryptococcal meningitis with antiphospholipid syndrome.
Zhao, J. P., Wu, X., Huang, Z., & Zhang, J. (2021) · PubMed Central · doi:10.11817/j.issn.1672-7347.2021.200471 · Cited by 4
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Khalil, I., Omer, I., Farh, I. Z. A., Mohamed, H. A., Elsharif, H. A., Mohamed, A. A. H., Awad‐Elkareem, M. A., & Salih, M. A. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/434779 · Cited by 4
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Xu, X.-F., Su, X.-L., Li, W.-P., Xu, L., Li, D.-C., Dai, K., Liu, J.-Y., Liu, J., Peng, F.-H., & Jiang, Y. (2025) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0013521 · Cited by 3
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Galnares‐Olalde, J. A., Loza-Jalil, S. E., Peña, F. G., Muñoz-Abraham, O., Pavía-Aubry, V., & de Luna-Gallardo, D. (2014) · Revista Médica Del Hospital General De México · doi:10.1016/j.hgmx.2014.08.004 · Cited by 3
The Changing Epidemiology of Cryptococcal Disease: A Retrospective Population-Based Study
George, I. A., Spec, A., Powderly, W. G., & Santos, C. A. Q. (2015) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofv133.1238 · Cited by 3
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Tan, X., Deng, M., Fang, Z., Yang, Q., Zhang, M., Wu, J., & Chen, W. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e30281 · Cited by 2
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Shivaswamy, R. P., Agarwal, M. P. M. A. B. B. M. K. K., Dang, M., Akbar, S., Ravikumar, Y., & Anil, D. (2023) · Journal of Dr. YSR University of Health Sciences. · doi:10.4103/jdrysruhs.jdrysruhs_221_22 · Cited by 2
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Yatsonsky, D., Gunn, J., Zajac, K. K., Burke, C., & Bair, J. M. (2024) · Journal of Orthopaedic Case Reports · doi:10.13107/jocr.2024.v14.i06.4488 · Cited by 2
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Yang, M., Cheng, L., Sun, F., Liu, F., Feng, W., Yao, P., Weng, B., & Xia, P. (2020) · Journal of International Medical Research · doi:10.1177/0300060520929591 · Cited by 2
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Becerra-Pedraza, L. C., Martínez‐Piña, D. A., Calles-Carmona, G. R., & San‐Juan, D. (2017) · Gaceta Médica de México · doi:10.24875/gmm.17002676 · Cited by 1
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Wo, M., Zhu, Y., Jiang, T., Ji, Y., & Ge, Y. (2024) · Jundishapur Journal of Microbiology · doi:10.5812/jjm-146577 · Cited by 1
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Bennett, S., Lopez, J. C. H., Glover, P. A., Steinberg, R., Saldana, C. S., & Terwilliger, T. (2024) · Journal of Investigative Medicine High Impact Case Reports · doi:10.1177/23247096241292230 · Cited by 1
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Ito, Y., Höeltermann, T.-A., Anjum, S. H., Robinson, L. J., Little, J. S., Kiritsy, M. C., Steinbrink, J. M., Finocchi, A., Walker, L. W., Avery, R. K., et al. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaf620 · Cited by 1
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Ghai, R. R., Benedict, K., Chiller, T. M., Chow, N. A., Hennessee, I., Jones, S., Lockhart, S. R., Lyman, M., Smith, D. J., Toda, M., et al. (2026) · Clinical Microbiology Reviews · doi:10.1128/cmr.00085-25 · Cited by 1
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Min, Z., Curtis, J. R., & Baddley, J. W. (2013) · Current Fungal Infection Reports · doi:10.1007/s12281-013-0156-8 · Cited by 1
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Xu, L., Huang, Q., Lin, J., Zhu, C.-Y., Li, X., Ye, S., Zhu, A., Chen, D.-H., Zhang, C., Chen, L., et al. (2016) · Medicine · doi:10.1097/md.0000000000002744 · Cited by 1
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He, K., Priyank, K., & Weber, D. M. (2019) · Infectious Diseases in Clinical Practice · doi:10.1097/ipc.0000000000000795 · Cited by 1
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Yoon, H., Hemmige, V. S., Lee, A., Conway-Pearson, L. S., Pirofski, L., & Felsen, U. R. (2022) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000003074 · Cited by 1
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Criptococosis cerebral: descripción de una serie de casos con presentaciones típicas y atípicas en el Hospital Universitario San José Infantil de Bogotá Cerebral cryptococcosis: description of a series of cases of atypical clinical presentation Hospital Universitario San José Infantil de Bogotá Trabajo original
Ramírez, S., Roa, L. F., Triana, J., Gómez‐Marín, J. E., Clavijo-Prado, C. A., Cárdenas, K., Salgado, S. A., & Batozhergalova, V. (2015) · Cited by 1
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Nunes, C. F. (2018) · doi:10.11606/t.99.2018.tde-27112018-144215 · Cited by 1
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Goés, L. D. O. (2019) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.6.2019.tde-28062019-093429 · Cited by 1
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Chaucanés, C. B. (2014) · RIUnB Institutional Repository (University of Brasília) · doi:10.26512/2014.11.d.16078
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Authors: Pyrgos, V., Seitz, A. E., Steiner, C. A., Prevots, D. R., & Williamson, P. R.
Affiliations: National Institutes of Health (US)
Agency for Healthcare Research and Quality (US)
Corresponding author: Williamson, Peter R.
ORCID: Seitz, Amy E.
Prevots, D. Rebecca
Williamson, Peter R.
Venue: PLoS ONE
Publisher: Public Library of Science (PLoS)
Published: 2013-02-15
Volume: 8
Issue: 2
Pages: e56269
ISSN: 1932-6203 (ISSN-L)
DOI: 10.1371/journal.pone.0056269
PMC: PMC3574138
OpenAlex: W1999868460
Semantic Scholar: 4b895d9fdf7ee8252fc83533890ec854af45ec8d
Cited by: 309
References: 41
Citations by year: 2026: 9 · 2025: 12 · 2024: 29 · 2023: 16 · 2022: 22 · 2021: 32 · 2020: 29 · 2019: 25 · 2018: 27 · 2017: 37 · 2016: 27 · 2015: 26 · 2014: 11 · 2013: 6
FWCI: 16.84
Type: journal article
Language: en
Open access: gold
doi.org
Licence: public-domain
creativecommons.org/publicdomain/zero/1.0/ (unspecified)
Locations: PLoS ONE (publishedVersion, public-domain)
Europe PMC (PubMed Central) (publishedVersion, other-oa)
PubMed Central (publishedVersion, public-domain)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: National Institutes of Health
Agency for Healthcare Research and Quality
National Institute of Allergy and Infectious Diseases
Topics: Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
Life Sciences › Immunology and Microbiology › Parasitology › Parasitic Infections and Diagnostics
Keywords: cryptococcal meningitis, incidence trends, hospitalization, in-hospital mortality, HIV-negative patients, comorbidities, hydrocephalus, renal failure, transplant recipients, immunodeficiency, Cushing's syndrome, hypogammaglobulinemia, hospital costs, United States
MeSH terms: Female, Hospitalization, Humans, Male, United States, HIV Infections, Comorbidity, Meningitis, Cryptococcal

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Epidemiology of Cryptococcal Meningitis in the US: 1997–2009

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