CYLD Deubiquitinates RIP1 in the TNFα-Induced Necrosome to Facilitate Kinase Activation and Programmed Necrosis
Cited by (321)
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- Additional file 7 of TNF-mediated neuroinflammation is linked to neuronal necroptosis in Alzheimer's disease hippocampusJayaraman, Anusha, Thein Than Htike, Rachel James, Carmen Picón, Reynolds, Richard · 2021 · Figshare
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- Deubiquitinating enzyme MINDY2 regulates TNF-α-induced cell death by targeting RIPK1Wenyang Huang, Yushi Chen, Danni Chen, Yuanyuan Liu, Jiaqin Lu, Jianting Feng, Juan Lin, Lisheng Li · 2026 · Cell Reports
- Caractérisation de nouveaux inhibiteurs de la kinase RIPK1 et de la nécroptoseFabienne Le Cann · 2017 · theses.fr (ABES)
- Étude de l’origine moléculaire de l’hétérogénéité de réponse cellulaire à TRAIL et son rôle dans la résistance non-génétiqueMickaël Meyer · 2020 · theses.fr (ABES)
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- The Ubiquitin System in Acute Lung Inflammatory InjuryJing Zhao, Yutong Zhao · 2025 · Springer eBooks
- Targeting RIPK1 for the treatment of depression: From neuroinflammation to synaptic plasticityX L Chen, Yu-Chi Zhuang, Wei Guan · 2026 · Biochemical Pharmacology
- lncRNA XIST suppresses acute myeloid leukemia progression by promoting necroptosis through the miR-92a-3p/CYLD axisXianbo Huang, Ying Chen, Yanling Ren, Shasha Wang, Chen Mei, Yu Xu, Jie Jin, Hongyan Tong, Jiejing Qian · 2026 · Cellular Signalling
- Necroptosis: The Regulation Between EGFR and TNFR in CancerJin Gyeom Kim, Wook Jin · 2026 · Cells
- CYLD restricts Japanese encephalitis virus pathogenic progression via blocking viral replication and virus-triggered GSDMD-dependent pyroptosis in neural cellsXinrui Zhang, Shuwen Guan, Linzhi Zhang, Zongyang Lv, Kanghao Ji, Zhen Ding, Ruiming Hu, Lingbao Kong, Huansheng Wu, Huali Xie et al. · 2026 · Veterinary Microbiology
- Comparative ubiquitinomics of human skin reveals insulin receptor ubiquitination as a regulator of collagen secretionJoseph Inns, Andrew Michael Frey, Ishier Raote, Hong Ha Nguyen, Mads Gyrd‐Hansen, Matthias Trost, Neil Rajan · 2026 · Communications Biology
- RIPK1 in Alzheimer’s Disease: A Context-Dependent Signaling Hub Linking Aβ, Tau, Neuroinflammation, and Regulated Cell DeathAntonella Caccamo, Marika Lanza, Giovanna Casili, Salvatore Oddo · 2026 · Cells
- E3 ubiquitin ligase-mediated necroptosis: regulatory mechanisms and therapeutic implication in cancerMingzhen Wei, Aiqin Sun · 2026 · Molecular Biology Reports
- From Proteostasis Disruption to Stone Formation: Ubiquitin-Dependent Regulatory Networks in Calcium Oxalate NephrolithiasisGuanwei Wu, Hualin Liu, Weiyu Zhu, Yingqing Liu, Haibo Qin, Lingsong Tao · 2026 · Biomedicines
- Influenza / S. aureus SuperinfectionVincent Tam, Alan Diercks · 2020 · ImmPort
- BindingDB Entry 50020999: RIPK1 inhibitors: A key to unlocking the potential of necroptosis in drug development.BindingDB · 2025 · UC San Diego
- BindingDB Entry 50008478: Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives.BindingDB · 2021 · UC San Diego