CYLD Deubiquitinates RIP1 in the TNFα-Induced Necrosome to Facilitate Kinase Activation and Programmed Necrosis

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

Micheau, O., & Tschopp, J. (2003) · Cell · doi:10.1016/s0092-8674(03)00521-x · Cited by 2,738

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

Sun, L., Wang, H., Wang, Z., He, S., Chen, S., Liao, D., Wang, L., Yan, J., Liu, W., Lei, X., et al. (2012) · Cell · doi:10.1016/j.cell.2011.11.031 · Cited by 2,698

Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Cho, Y., Challa, S., Moquin, D., Genga, R., Ray, T. D., Guildford, M., & Chan, F. K.-M. (2009) · Cell · doi:10.1016/j.cell.2009.05.037 · Cited by 2,435

Molecular mechanisms of necroptosis: an ordered cellular explosion

Vandenabeele, P., Galluzzi, L., Vanden Berghe, T., & Kroemer, G. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2970 · Cited by 2,382

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

He, S., Wang, L., Miao, L., Wang, T., Du, F., Zhao, L., & Wang, X. (2009) · Cell · doi:10.1016/j.cell.2009.05.021 · Cited by 2,214

RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis

Zhang, D.-W., Shao, J., Lin, J., Zhang, N., Lu, B.-J., Lin, S.-C., Dong, M.-Q., & Han, J. (2009) · Science · doi:10.1126/science.1172308 · Cited by 1,931

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling

Wertz, I. E., O’Rourke, K. M., Zhou, H., Eby, M. T., Aravind, L., Seshagiri, S., Wu, P., Wiesmann, C., Baker, R. T., Boone, D. L., et al. (2004) · Nature · doi:10.1038/nature02794 · Cited by 1,889

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

Wang, L., Du, F., & Wang, X. (2008) · Cell · doi:10.1016/j.cell.2008.03.036 · Cited by 1,398

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

Oberst, A., Dillon, C. P., Weinlich, R., McCormick, L. L., Fitzgerald, P., Pop, C., Hakem, R., Salvesen, G. S., & Green, D. R. (2011) · Nature · doi:10.1038/nature09852 · Cited by 1,278 · cited 1×

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

Li, J., McQuade, T., Siemer, A. B., Napetschnig, J., Moriwaki, K., Hsiao, Y.-S., Damko, E., Moquin, D., Walz, T., McDermott, A., et al. (2012) · Cell · doi:10.1016/j.cell.2012.06.019 · Cited by 1,222

Diverse pathways to neuronal necroptosis in Alzheimer's disease

Jayaraman, A., & Reynolds, R. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15662 · Cited by 21

Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death

Liu, L., Sandow, J. J., Pedrioli, D. M. L., Samson, A. L., Silke, N., Kratina, T., Ambrose, R. L., Doerflinger, M., Hu, Z., Morrish, E., et al. (2022) · Science Advances · doi:10.1126/sciadv.abh2332 · Cited by 24

Programmed necrosis and its role in management of breast cancer

Thakur, B., Kumar, Y., & Bhatia, A. (2019) · Pathology - Research and Practice · doi:10.1016/j.prp.2019.152652 · Cited by 21

Tumor-intrinsic and immune modulatory roles of receptor-interacting protein kinases

Rucker, A. J., & Chan, F. K.-M. (2022) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2021.12.004 · Cited by 20

Necroptosis in human cancers with special emphasis on oral squamous cell carcinoma

Krishnan, R. P., Pandiar, D., Ramani, P., & Jayaraman, S. (2023) · Journal of Stomatology Oral and Maxillofacial Surgery · doi:10.1016/j.jormas.2023.101565 · Cited by 21

Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer

Zhang, X., Chen, X., Qian, F., Zhu, Y., He, G., Yang, J., Wu, X., Zhang, H., Yu, X., & Liu, X. (2023) · Clinical and Translational Medicine · doi:10.1002/ctm2.1398 · Cited by 20

Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity

Saleh, D., & Degterev, A. (2015) · Current topics in microbiology and immunology · doi:10.1007/82_2015_449 · Cited by 19

Deubiquitinating Enzymes: A Critical Regulator of Mitosis

Park, J., Cho, J., Kim, E. E., & Song, E. J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20235997 · Cited by 19

Ketamine inhibits TNF-α-induced cecal damage by enhancing RIP1 ubiquitination to attenuate lethal SIRS

Deng, B., Yang, D., Wu, H., Wang, L., Wu, R., Zhu, H., Huang, A., Song, J., Cai, T., Liu, S., et al. (2022) · Cell Death Discovery · doi:10.1038/s41420-022-00869-x · Cited by 18

Viral-induced neuronal necroptosis: Detrimental to brain function and regulation by necroptosis inhibitors

Panda, S. P., Kesharwani, A., Mallick, S. P., Prasanth, D., Pasala, P. K., & Tatipamula, V. B. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115591 · Cited by 18

Cell Death Pathways

Kim‐Campbell, N., Gómez, H., & Bayır, H. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-44942-7.00020-0 · Cited by 18

The necroptosis pathway and its role in age-related neurodegenerative diseases: will it open up new therapeutic avenues in the next decade?

Salvadores, N., & Court, F. A. (2020) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2020.1758668 · Cited by 18

Negative Regulation of the Innate Immune Response through Proteasomal Degradation and Deubiquitination

Budroni, V., & Versteeg, G. A. (2021) · Viruses · doi:10.3390/v13040584 · Cited by 21

The death-inducing activity of RIPK1 is regulated by the pH environment

Moriwaki, K., Balaji, S., & Chan, F. K.-M. (2020) · Science Signaling · doi:10.1126/scisignal.aay7066 · Cited by 18

Deubiquitinases: Modulators of Different Types of Regulated Cell Death

Lee, C.-S., Kim, S., Hwang, G., & Song, J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094352 · Cited by 17

Receptor Interacting Protein Kinases 1/3: The Potential Therapeutic Target for Cardiovascular Inflammatory Diseases

Leng, Y., Zhang, Y., Li, X., Wang, Z., Zhuang, Q., & Lu, Y. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.762334 · Cited by 18

Necroptosis at a glance

Kang, K., Park, C., & Chan, F. K.-M. (2022) · Journal of Cell Science · doi:10.1242/jcs.260091 · Cited by 19

MALT1 promotes necroptosis in stroke rat brain via targeting the A20/RIPK3 pathway

Peng, Z.-M., Zhang, Y., Dan, W., Zhang, X., Liu, B., Peng, J., & Luo, X. (2023) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2023.109502 · Cited by 16

Immune dysregulation in SHARPIN-deficient mice is dependent on CYLD-mediated cell death

Ang, R. L., Chan, M., Legarda, D., Sundberg, J. P., Sun, S., Gillespie, V., Chun, N. H., Heeger, P. S., Xiong, H., Lira, S. A., et al. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2001602118 · Cited by 16

Progress in studies of necroptosis and its relationship to disease processes

Wang, Z., Guo, L., Wang, S., Chen, D., Yan, J., Liu, F., Huang, J.-F., & Xiong, K. (2018) · Pathology - Research and Practice · doi:10.1016/j.prp.2018.09.002 · Cited by 15

Burning controversies in NETs and autoimmunity: The mysteries of cell death and autoimmune disease

Dwivedi, N., & Radic, M. Z. (2018) · Autoimmunity · doi:10.1080/08916934.2018.1523395 · Cited by 18

The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGFβ Signaling

Pseftogas, A., Xanthopoulos, K., Poutahidis, T., Ainali, C., Dafou, D., Panteris, E., Kern, J. G., Varelas, X., Hardas, A., Gonidas, C., et al. (2020) · Cancers · doi:10.3390/cancers12082047 · Cited by 15

Carbamoylating Activity Associated with the Activation of the Antitumor Agent Laromustine Inhibits Angiogenesis by Inducing ASK1-Dependent Endothelial Cell Death

Ji, W., Yang, M., Praggastis, A., Li, Y., Zhou, H. J., He, Y., Ghazvinian, R., Cincotta, D. J., Rice, K. P., & Wang, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103224 · Cited by 14

Proteolytic control of regulated necrosis

Chico, J. F., Saggau, C., & Adam, D. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2017.05.025 · Cited by 16

Receptor-Interacting Protein Kinase 1 (RIPK1) as a Potential Therapeutic Target: An Overview of Its Possible Role in the Pathogenesis of Alzheimer's Disease

Chan, H. H., Koh, R. Y., Lim, C. L., & Leong, C. O. (2019) · Current Alzheimer Research · doi:10.2174/1567205016666191023102422 · Cited by 15

Non-coding RNAs in necroptosis, pyroptosis, and ferroptosis in cardiovascular diseases

Cai, Y., Zhou, Y., Li, Z., Xia, P., ChenFu, X., Shi, A., Zhang, J., & Yu, P. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.909716 · Cited by 14

Cationic peroxidase from proso millet induces human colon cancer cell necroptosis by regulating autocrine TNF-α and RIPK3 demethylation

Cui, X., Wang, R., & Wang, Z. (2018) · Food & Function · doi:10.1039/c7fo01040k · Cited by 14

A biochemical necroptosis model explains cell-type-specific responses to cell death cues

Ildefonso, G. V., Metzig, M. O., Hoffmann, A., Harris, L. A., & Lopez, C. F. (2023) · Biophysical Journal · doi:10.1016/j.bpj.2023.01.035 · Cited by 14

Tumor necrosis factor related apoptosis inducing ligand (TRAIL) regulates deubiquitinase USP5 in tumor cells

Potu, H., Kandarpa, M., Peterson, L. F., Donato, N. J., & Talpaz, M. (2019) · Oncotarget · doi:10.18632/oncotarget.27196 · Cited by 13

N-arachidonoylphenolamine alleviates ischaemia/reperfusion-induced cardiomyocyte necroptosis by restoring proteasomal activity

Bai, J.-Q., Li, P., Li, H., & Li, H. (2023) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2023.176235 · Cited by 12

Exploitation of necroptosis for treatment of caspase-compromised cancers

Cho, Y. S., & Park, H. L. (2017) · Oncology Letters · doi:10.3892/ol.2017.6285 · Cited by 12

Inactivation of CYLD in intestinal epithelial cells exacerbates colitis-associated colorectal carcinogenesis - a short report

Καρατζάς, Δ., Xanthopoulos, K., Kotantaki, P., Pseftogas, A., Teliousis, K., Hatzivassiliou, E., Kontoyiannis, D. L., Poutahidis, T., & Mosialos, G. (2016) · Cellular Oncology · doi:10.1007/s13402-016-0279-3 · Cited by 12

Necroptosis in Pneumonia: Therapeutic Strategies and Future Perspectives

Mei, X., Zhang, Y., Wang, S., Wang, H., Chen, R., Ma, K., Yang, Y., Jiang, P., Feng, Z., Zhang, C., et al. (2024) · Viruses · doi:10.3390/v16010094 · Cited by 11

Activation of peroxisome proliferator-activated receptor gamma in mammary epithelial cells upregulates the expression of tumor suppressor Cyld to mediate growth inhibition and anti-inflammatory effects

Pseftogas, A., Gonidas, C., & Mosialos, G. (2016) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2016.11.011 · Cited by 11

Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling

Carman, L. E., Samulevich, M. L., & Aneskievich, B. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241511943 · Cited by 10

Cullin Deneddylation Suppresses the Necroptotic Pathway in Cardiomyocytes

Lewno, M. T., Cui, T., & Wang, X. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.690423 · Cited by 10

RIPK1-TRAF2 interplay on the TNF/NF-κB signaling, cell death, and cancer development in the liver

Yamamoto, S., & Iwakuma, T. (2017) · Translational Cancer Research · doi:10.21037/tcr.2017.04.01 · Cited by 9

The roles of long non-coding RNAs in the necroptotic signaling of colon cancer cells

Bozgeyi̇k, E., Bağış, H., Bozgeyik, İ., & Kocahan, S. (2023) · Molecular Biology Reports · doi:10.1007/s11033-023-08441-1 · Cited by 9

Regulation of apoptosis by ubiquitination in liver cancer.

Li, Y., Zhu, J., Yu, Z., Zhai, F., Li, H., & Jin, X. (2023) · PubMed Central · Cited by 14

Beneficial effects of chlorogenic acid treatment on neuroinflammation after deep hypothermic circulatory arrest may be mediated through CYLD/NF-κB signaling

Chen, Q., Lei, Y., Liu, J., Wang, Z., & Cao, H. (2021) · Brain Research · doi:10.1016/j.brainres.2021.147572 · Cited by 9

The p38/CYLD Pathway is Involved in Necroptosis Induced by Oxygen-glucose Deprivation Combined with ZVAD in Primary Cortical Neurons

Feng, T., Chen, W., Zhang, C., Xiang, J., Ding, H., Wu, L., & Geng, D. (2017) · Neurochemical Research · doi:10.1007/s11064-017-2244-6 · Cited by 9

Chemical regulation of signaling pathways to programmed necrosis

Bae, J. H., Shim, J., & Cho, Y. S. (2014) · Archives of Pharmacal Research · doi:10.1007/s12272-014-0385-6 · Cited by 9

Autophagy and Cell Death in Alzheimer’s, Parkinson’s and Prion Diseases

Ribarič, S., & Ribarič, I. M. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.86706 · Cited by 9

Synthesis and preclinical evaluation of 11C-labeled 7-Oxo-2,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridine radioligands for RIPK1 positron emission tomography imaging

Luo, T.-W., Sang, N., Liu, Y., Zhou, Y., Wu, R. X., Bagdasarian, F. A., Wey, H., Lang, J., Wang, C., & Bai, P. (2024) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2024.107279 · Cited by 8

Emerging Insights Into Necroptosis: Implications for Renal Health and Diseases

Gupta, A., Chakole, S. V., Agrawal, S., Khekade, H., Prasad, R., Lohakare, T., & Wanjari, M. B. (2023) · Cureus · doi:10.7759/cureus.43609 · Cited by 8

Alzheimer’s disease: a jigsaw puzzle comprised of different types of programmed cell death pieces

Wang, Y., Mu, D., Li, Y., Liu, C., Feng, J., Lai, Y., & Lou, G. (2025) · Brain Research · doi:10.1016/j.brainres.2025.149861 · Cited by 7

Relationship between the expression of TNFR1-RIP1/RIP3 in peripheral blood and cognitive function in occupational Al-exposed workers: A mediation effect study

Zhang, J., Hao, Y., Wang, Y., Han, Y., Zhang, S., & Niu, Q. L. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2021.130484 · Cited by 7

Programmed cell death in cancer: targeting necroptosis to kill tumor cell

Liang, J., Tan, C., Li, X., Fan, J., & Liu, B. (2026) · Cell Death Discovery · doi:10.1038/s41420-026-03002-4 · Cited by 7

Necroptosis in the sarcoma immune microenvironment: From biology to therapy

Ye, H., Lu, M., Tu, C., & Li, M. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110603 · Cited by 6

Necroptosis in obesity: a complex cell death event

Liu, Z., Wang, S., Wang, W., Lv, R., & Sun, C. (2024) · APOPTOSIS · doi:10.1007/s10495-024-02055-z · Cited by 7

Cross-regulation of Listeria monocytogenes and the host ubiquitin system in listeriosis

Zhuang, Y., Fischer, J. B., Nishanth, G., & Schlüter, D. (2024) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2024.151401 · Cited by 6

SPATA2 – Keeping the TNF signal short and sweet

Feltham, R., Webb, A. I., & Silke, J. (2016) · The EMBO Journal · doi:10.15252/embj.201695061 · Cited by 6

Necroptosis, ADAM proteases and intestinal (dys)function

Heib, M., Rose‐John, S., & Adam, D. (2020) · International review of cytology · doi:10.1016/bs.ircmb.2020.02.001 · Cited by 7

The good, the bad, and the modified: CYLD’s post-translational tale

Macé, Y., Bidère, N., & Douanne, T. (2025) · Frontiers in Cell Death · doi:10.3389/fceld.2025.1583221 · Cited by 5

Deubiquitinases in metabolic diseases, fibrosis and cancer of the liver

Thakur, A., Kubaichuk, K. I., & Kietzmann, T. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2025.120021 · Cited by 5

CYLD suppresses LPS-induced inflammation through RIP1 deubiquitination in rainbow trout

Jang, J. H., Kim, H. R., Kim, H. J., & Cho, J. H. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110489 · Cited by 5

Dovitinib Ameliorates Inflammation-Related Diseases by Inhibiting Necroptosis and Ferroptosis

Lin, Y., Feng, J., Zhao, M., Zhang, L., Li, Y., Chen, X., Lin, C., Lin, J., Lin, Q., Li, J., et al. (2025) · ACS Chemical Biology · doi:10.1021/acschembio.5c00327 · Cited by 5

RIP1-dependent Apoptosis and Differentiation Regulated by Skp2 and Akt/GSK3β in Acute Myeloid Leukemia

Dan, W., Zhong, L., Zhang, Z., Wan, P., Lu, Y., Wang, X., Liu, Z., Chu, X., & Liu, B. (2022) · International Journal of Medical Sciences · doi:10.7150/ijms.68385 · Cited by 5

Establishment of a Necroptosis Related Genes Signature to Predict Prognosis and Therapeutic Response in Colon Cancer

Wang, Y., Huang, Y., Li, C., Wang, X., Yang, M., Xu, D., Liu, B., & Yuan, X. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.921320 · Cited by 5

Exploiting Cell Death Pathways for Inducible Cell Elimination to Modulate Graft-versus-Host-Disease

Falcon, C., Al‐Obaidi, M., & Stasi, A. D. (2017) · Biomedicines · doi:10.3390/biomedicines5020030 · Cited by 5

IKK-mediated CYLD phosphorylation and cellular redox activity

Erol, A. (2022) · Molecular Medicine · doi:10.1186/s10020-022-00439-y · Cited by 5

Cyld restrains the hyperactivation of synovial fibroblasts in inflammatory arthritis by regulating the TAK1/IKK2 signaling axis

Rinotas, V. E., Iliaki, K. K., Pavlidi, L., Meletakos, T., Mosialos, G., & Armaka, M. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06966-2 · Cited by 4

Trigger Points of Necroptosis (RIPK1, RIPK3, and MLKL)—Promising Horizon or Blind Alley in Therapy of Colorectal Cancer?

Sokołowski, M., & Butrym, A. K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262211101 · Cited by 5

Tob negatively regulates NF-κB activation in breast cancer through its association with the TNF receptor complex

Tokumasu, M., Sato, A., Ito-Kureha, T., Yamamoto, M., Ohmine, N., Semba, K., Inoue, J., & Yamamoto, T. S. (2025) · Cancer Gene Therapy · doi:10.1038/s41417-025-00897-6 · Cited by 4

Polymorphisms in Necroptosis Pathway Genes: Novel Prognostic Markers for Multiple Myeloma Treatment Outcomes

Sokołowski, M., Łacina, P., Bogunia‐Kubik, K., Mazur, G. J., & Butrym, A. K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26115237 · Cited by 4

Inhibition of TBK1/IKKε mediated RIPK1 phosphorylation sensitizes tumors to immune cell killing

Piskopou, A., Vredevoogd, D. W., Kong, X., Peeper, D. S., Altelaar, M. A. F., & Stecker, K. E. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02841-x · Cited by 4

USP13 depletion sensitizes colorectal cancer cells to necroptosis by destabilizing cIAP2 proteins

Kim, Y. J., Das, T., Park, J., Hwang, I., Kim, E. E., & Song, E. J. (2025) · Cell Death and Differentiation · doi:10.1038/s41418-025-01595-4 · Cited by 3

Cell Injury and Necrosis

d’Avila, J. C., Levin, S., & Radi, Z. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.64220-4 · Cited by 3

Mutations in Necroptosis-Related Genes Reported in Breast Cancer: A Cosmic and Uniport Database-Based Study

Thakur, B., Verma, R. K., & Bhatia, A. (2024) · Clinical Breast Cancer · doi:10.1016/j.clbc.2024.12.008 · Cited by 3

Septic shock: innate molecular genetic mechanisms of the development of generalized inflammation

Kurmyshkina, O. V., Aa, B., Volkova, T. O., & Poltorak, A. (2015) · Russian Journal of Developmental Biology · doi:10.1134/s1062360415040062 · Cited by 3

SPARC ectopic overexpression inhibits growth and promotes programmed cell death in acute myeloid leukemia transformed from myelodysplastic syndrome cells, alone and in combination with Ara-C treatment

Nian, Q., Chi, J., Xiao, Q., Wei, C., Costeas, P., Yang, Z., Liu, L., & WANG, L. (2015) · Oncology Reports · doi:10.3892/or.2015.4114 · Cited by 3

Release mechanism of high mobility group nucleosome binding domain 1 from lipopolysaccharide-stimulated macrophages

Murakami, T., Hu, Z., Tamura, H., & Nagaoka, I. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.4893 · Cited by 3

Ubiquitin-specific proteases as targets for anticancer drug therapies

Campos-Iglesias, D., López-Otín, C., & Freije, J. M. P. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818168-3.00004-8 · Cited by 4

Necroptosis

Croker, B. A., Rickard, J. A., Shlomovitz, I., Al‐Obeidi, A., D’Cruz, A. A., & Gerlic, M. (2018) · Wiley eBooks · doi:10.1002/9781119432463.ch6 · Cited by 3

Macrophage-associated kinase signaling in atherosclerosis – a systematic review

Müller, J. S., & van der Vorst, E. P. C. (2026) · Cell Communication and Signaling · doi:10.1186/s12964-026-02829-9 · Cited by 2

Delayed necrostatin-1s infusion attenuates cystic white matter injury in preterm fetal sheep

Lear, B. A., Lear, C. A., Dhillon, S. K., King, V. J., Dean, J. M., Davidson, J. O., Gunn, A. J., & Bennet, L. (2025) · Neurotherapeutics · doi:10.1016/j.neurot.2025.e00775 · Cited by 2

Programmed cell death dynamics during hyperglycemia and ischemic brain injuries.

LaRocca, T. J. (2016) · doi:10.35841/neurology-neurorehabilitation.1.2.49-54 · Cited by 2

Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages

Siokas, I., Zhang, D., Poltorak, A., Muendlein, H. I., & Degterev, A. (2021) · Current Protocols · doi:10.1002/cpz1.156 · Cited by 2

Ars moriendi: Proteases as sculptors of cellular suicide

Heib, M., Weiß, J., Saggau, C., Hoyer, J., Chico, J. F., Voigt, S., & Adam, D. (2021) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2021.119191 · Cited by 2

Interaction of HIF-1a with various cell death pathways in tumor immune microenvironment (TIME)

Varkiani, M. M., Faghihkhorasani, F., Moosavi, M., Habibi, R., Mirzaei, H., Karimi, N., Etemad, S., Karami, P., Osati, P., Aref, A. R., et al. (2026) · APOPTOSIS · doi:10.1007/s10495-025-02249-z · Cited by 6

CYLD-mediated DNA damage coordinates pathological cardiac hypertrophy via RIPK1-dependent signaling

Jiang, X., Shi, M., Guo, J., Zhang, J., Li, D., 范祖军, Ren, F., Wu, S., Zeng, J., Wu, J., et al. (2026) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2026.03.005 · Cited by 1

Functional Relevance of Deubiquitinases in Life and Disease

Fraile, J. M., López-Otı́n, C., & Freije, J. M. P. (2017) · Springer eBooks · doi:10.1007/978-981-10-2513-6_16 · Cited by 1

Nekroptozis: Serebral ve Miyokardiyal İskemi/Reperfüzyon Hasarı için Terapötik bir Hedef midir?

Yılmaz, Z. (2023) · Harran Üniversitesi Tıp Fakültesi Dergisi · doi:10.35440/hutfd.1341349 · Cited by 1

Urea overdose causes pathological injury and activates necroptosis in lung of Jianzhou Da’er Goat (Capra hircus)

Qiu, M., Zhang, H., Wang, L., Wei, Y., Emu, Q., Yang, S., & Wang, L. (2023) · Small Ruminant Research · doi:10.1016/j.smallrumres.2023.107143 · Cited by 1

The Effect of Psoralea corylifolia (Babchi) on Neuronal Apoptosis Induced by Palmitate in PC12 Cells and its Role in Alzheimer’s Disease: A Review

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