The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Lactobacillus rhamnosus GG Protects against Non-Alcoholic Fatty Liver Disease in Mice
Open accessAbstract
OBJECTIVE: Experimental evidence revealed that obesity-associated non-alcoholic fatty liver disease (NAFLD) is linked to changes in intestinal permeability and translocation of bacterial products to the liver. Hitherto, no reliable therapy is available except for weight reduction. Within this study, we examined the possible effect of the probiotic bacterial strain Lactobacillus rhamnosus GG (LGG) as protective agent against experimental NAFLD in a mouse model. METHODS: Experimental NAFLD was induced by a high-fructose diet over eight weeks in C57BL/J6 mice. Fructose was administered via the drinking water containing 30% fructose with or without LGG at a concentration resulting in approximately 5×10(7) colony forming units/g body weight. Mice were examined for changes in small intestinal microbiota, gut barrier function, lipopolysaccharide (LPS) concentrations in the portal vein, liver inflammation and fat accumulation in the liver. RESULTS: LGG increased beneficial bacteria in the distal small intestine. Moreover, LGG reduced duodenal IκB protein levels and restored the duodenal tight junction protein concentration. Portal LPS (P≤0.05) was reduced and tended to attenuate TNF-α, IL-8R and IL-1β mRNA expression in the liver feeding a high-fructose diet supplemented with LGG. Furthermore liver fat accumulation and portal alanine-aminotransferase concentrations (P≤0.05) were attenuated in mice fed the high-fructose diet and LGG. CONCLUSIONS: We show for the first time that LGG protects mice from NAFLD induced by a high-fructose diet. The underlying mechanisms of protection likely involve an increase of beneficial bacteria, restoration of gut barrier function and subsequent attenuation of liver inflammation and steatosis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“binge alcohol exposure [232], [233], [234], [235], [236], [237], [238], [239] and nonalcoholic substances including fructose [240], [241], [242] are known to promote gut leakiness, contributing to more severe inflammatory liver disease.”
In the citing paper
“binge alcohol exposure [232], [233], [234], [235], [236], [237], [238], [239] and nonalcoholic substances including fructose [240], [241], [242] are known to promote gut leakiness, contributing to more severe inflammatory liver disease.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
An obesity-associated gut microbiome with increased capacity for energy harvest
Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444
Human gut microbes associated with obesity
Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006) · Nature · doi:10.1038/4441022a · Cited by 8,785
Nonalcoholic Fatty Liver Disease
Angulo, P. (2002) · New England Journal of Medicine · doi:10.1056/nejmra011775 · Cited by 5,228
Cani, P. D., Bibiloni, R., Knauf, C., Waget, A., Neyrinck, A. M., Delzenne, N. M., & Burcelin, R. (2008) · Diabetes · doi:10.2337/db07-1403 · Cited by 4,819
Prevalence of Hepatic Steatosis in An Urban Population in the United States: Impact of Ethnicity
Browning, J. D., Szczepaniak, L. S., Dobbins, R., Nuremberg, P., Horton, J. D., Cohen, J. C., Grundy, S. M., & Hobbs, H. H. (2004) · Hepatology · doi:10.1002/hep.20466 · Cited by 3,664
Microbiota and SCFA in lean and overweight healthy subjects
Schwiertz, A., Taras, D., Schäfer, K., Beijer, S., Bos, N. A., Donus, C., & Hardt, P. D. (2010) · Obesity · doi:10.1038/oby.2009.167 · Cited by 2,457
Self-citationInflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
Henao-Mejia, J., Elinav, E., Jin, C., Hao, L., Mehal, W. Z., Strowig, T., Thaiss, C. A., Kau, A. L., Eisenbarth, S. C., Jurczak, M. J., et al. (2012) · Nature · doi:10.1038/nature10809 · Cited by 2,435
Peng, L., Li, Z.-R., Green, R. S., Holzmanr, I. R., & Lin, J. (2009) · The Journal of Nutrition · doi:10.3945/jn.109.104638 · Cited by 2,130
Nonalcoholic fatty liver disease
Adams, L. A. (2005) · Canadian Medical Association Journal · doi:10.1503/cmaj.045232 · Cited by 1,658
Genes and Molecules of Lactobacilli Supporting Probiotic Action
Lebeer, S., Vanderleyden, J., & De Keersmaecker, S. C. J. (2008) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00017-08 · Cited by 1,013
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–200 of 291
Kobyliak, N. M., Falalyeyeva, T. M., Bodnar, P., & Beregova, T. V. (2016) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-016-9230-1 · Cited by 56
Role of diet on non-alcoholic fatty liver disease: An updated narrative review
Papandreou, D. (2015) · World Journal of Hepatology · doi:10.4254/wjh.v7.i3.575 · Cited by 55
Qiu, P., Dong, Y. H., Zhu, T., Luo, Y., Kang, X., Pang, M.-X., Li, H., Xu, H., Gu, C., Pan, S.-H., et al. (2018) · Phytomedicine · doi:10.1016/j.phymed.2018.09.209 · Cited by 54
NAFLD, Helicobacter species and the intestinal microbiome
Castaño‐Rodríguez, N., Mitchell, H. M., & Kaakoush, N. O. (2017) · Best Practice & Research Clinical Gastroenterology · doi:10.1016/j.bpg.2017.09.008 · Cited by 53
The role of gut microbiota in liver disease development and treatment
Wang, L., & Wan, Y. Y. (2019) · Liver Research · doi:10.1016/j.livres.2019.02.001 · Cited by 53
Ni, Y., Ni, L., Zhuge, F., & Fu, Z. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000375 · Cited by 53
Nutritional Approaches to Achieve Weight Loss in Nonalcoholic Fatty Liver Disease
Hsu, C. C.-S., Ness, E. M., & Kowdley, K. V. (2017) · Advances in Nutrition · doi:10.3945/an.116.013730 · Cited by 53
Kuraji, R., Shiba, T., Dong, T. S., Numabe, Y., & Kapila, Y. L. (2023) · World Journal of Gastroenterology · doi:10.3748/wjg.v29.i6.967 · Cited by 53
Rivero‐Gutiérrez, B., Gámez‐Belmonte, R., Suárez, M. D., Lavín, J. L., Aransay, A. M., Olivares, M. M., Martínez‐Augustin, O., de Medina, F. S., & Zarzuelo, A. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600622 · Cited by 50
Omega-3 Fatty Acids and Gut Microbiota: A Reciprocal Interaction in Nonalcoholic Fatty Liver Disease
Shama, S., & Liu, W. (2020) · Digestive Diseases and Sciences · doi:10.1007/s10620-020-06117-5 · Cited by 51
Fan, L., Ma, S., Li, L., & Huang, J. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.133529 · Cited by 48
Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease
Jarmakiewicz-Czaja, S., Sokal-Dembowska, A., Pardak, P., & Filip, R. (2022) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/2022/4344905 · Cited by 48
Zhao, C., Liu, L., Liu, Q., Li, F., Zhang, L., Zhu, F., Shao, T., Barve, S. S., Chen, Y., Li, X., et al. (2019) · Molecular Metabolism · doi:10.1016/j.molmet.2019.08.020 · Cited by 47
Han, Y., Park, H., Choi, B.-R., Ji, Y., Kwon, E., & Choi, M. (2020) · Nutrients · doi:10.3390/nu12020352 · Cited by 45
Gut microbiome, gut function, and probiotics: Implications for health
Hajela, N., Ramakrishna, B., Nair, G. B., Abraham, P., Gopalan, S., & Ganguly, N. K. (2015) · Indian Journal of Gastroenterology · doi:10.1007/s12664-015-0547-6 · Cited by 47
Zubiría, M. G., Gambaro, S. E., Rey, M., Carasi, P., Serradell, M. D. L. Á., & Giovambattista, A. (2017) · Nutrients · doi:10.3390/nu9050470 · Cited by 45
Probiotic strains and mechanistic insights for the treatment of type 2 diabetes
Hampe, C. S., & Roth, C. L. (2017) · Endocrine · doi:10.1007/s12020-017-1433-z · Cited by 46
Kuraji, R., Ye, C., Zhao, C., Gao, L., Martínez, A., Miyashita, Y., Radaic, A., Kamarajan, P., Le, C., Zhan, L., et al. (2024) · npj Biofilms and Microbiomes · doi:10.1038/s41522-024-00476-x · Cited by 45
Ye, H., Li, Q., Zhang, Z., Sun, M.-C., Zhao, C., & Zhang, T. (2017) · Food & Function · doi:10.1039/c7fo01108c · Cited by 43
Efficacy of Probiotics and Smectite in Rats with Non-Alcoholic Fatty Liver Disease
Kobyliak, N. M., Abenavoli, L., Falalyeyeva, T. M., & Beregova, T. V. (2017) · Annals of Hepatology · doi:10.5604/01.3001.0010.7547 · Cited by 42
Microbial Impact on Host Metabolism: Opportunities for Novel Treatments of Nutritional Disorders?
Plovier, H., & Cani, P. D. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.bad-0002-2016 · Cited by 44
Fructose: a modulator of intestinal barrier function and hepatic health?
Staltner, R., Burger, K., Baumann, A., & Bergheim, I. (2023) · European Journal of Nutrition · doi:10.1007/s00394-023-03232-7 · Cited by 42
Self-citationKobyliak, N. M., Falalyeyeva, T. M., Virchenko, O., Mykhalchyshyn, G., Bodnar, P., NIa, S., Yankovsky, D., Beregova, T. V., & Остапченко, Л. І. (2016) · BMC Gastroenterology · doi:10.1186/s12876-016-0451-2 · Cited by 40
Modulation of gut microbiome in nonalcoholic fatty liver disease: pro-, pre-, syn-, and antibiotics
Cho, M. S., Kim, S. Y., Suk, K. T., & Kim, B. (2018) · The Journal of Microbiology · doi:10.1007/s12275-018-8346-2 · Cited by 42
Kwon, J., Kim, B., Lee, C., Joung, H., Kim, B.-K., Choi, I. S., & Hyun, C. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228932 · Cited by 39
Yang, B. K., Zheng, F., Stanton, C., Ross, R. P., Zhao, J., Zhang, H., & Chen, W. (2021) · Foods · doi:10.3390/foods10092081 · Cited by 39
Barta, G., Cornea‐Cipcigan, M., Mărgăoan, R., & Vodnar, D. C. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.871896 · Cited by 39
Kaufmann, B. K., Seyfried, N., Hartmann, D., & Hartmann, P. (2023) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00017.2023 · Cited by 40
Schoemaker, M. H., Kleemann, R., Morrison, M. C., Verheij, J., Salic, K., van Tol, E. A. F., Kooistra, T., & Wielinga, P. Y. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180648 · Cited by 37
Luo, D., Yang, L., Pang, H., Zhao, Y., Li, K., Rong, X., & Guo, J. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.984019 · Cited by 34
The Role of Diet, Additives, and Antibiotics in Metabolic Endotoxemia and Chronic Diseases
Park, J., Park, H., Kim, Y., & Park, M. (2024) · Metabolites · doi:10.3390/metabo14120704 · Cited by 41
Korkmaz, Ö. A., Şumlu, E., Koca, H. B., Pektaş, M. B., Kocabaş, A., Sadı, G., & Akar, F. (2019) · Medicina · doi:10.3390/medicina55050207 · Cited by 35
Hu, S., Tang, B., Lu, C. C., Wang, S., Wu, L., Lei, Y., Tang, L., Zhu, H., Wang, D., & Yang, S. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107275 · Cited by 37
Crucial functions of gut microbiota on gut–liver repair
Wang, Y., Yan, H., Zheng, Q., & Sun, X. (2025) · hLife · doi:10.1016/j.hlife.2025.01.001 · Cited by 39
Arellano-García, L., Portillo, M. P., Martínez, J. A., & Milton‐Laskibar, I. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063167 · Cited by 37
Age-Related NAFLD: The Use of Probiotics as a Supportive Therapeutic Intervention
Campagnoli, L. I. M., Marchesi, N., Vairetti, M., Pascale, A., Ferrigno, A., & Barbieri, A. (2022) · Cells · doi:10.3390/cells11182827 · Cited by 36
Reshef, N., Gophna, U., Reshef, L., Konikoff, F. M., Gabay, G., Zornitzki, T., Knobler, H., & Maor, Y. (2024) · Nutrients · doi:10.3390/nu16111571 · Cited by 35
López-Almada, G., Mejía-León, M. E., & Salazar‐López, N. J. (2024) · Foods · doi:10.3390/foods13223529 · Cited by 36
Abdollahi, M. R., Abdolghaffari, A. H., Gooshe, M., & Ghasemi‐Niri, S. F. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-802189-7.00015-0 · Cited by 32
Next‐Generation Probiotics: From Traditional Strains to Personalized Therapeutics
Jadhav, N. K., Magdum, A. B., Shinde, K. V., & Nimbalkar, M. S. (2026) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.70339 · Cited by 29
Insights into the Anti-Adipogenic and Anti-Inflammatory Potentialities of Probiotics against Obesity
Kober, A. K. M. H., Saha, S., Ayyash, M. M., Namai, F., Nishiyama, K., Yoda, K., Villena, J., & Kitazawa, H. (2024) · Nutrients · doi:10.3390/nu16091373 · Cited by 31
Adhesion and Colonization of the Probiotic Lactobacillus rhamnosus Labeled by Dsred2 in Mouse Gut
Li, C., Bei, T., Niu, Z., Guo, X. N., Wang, M., Lu, H., Gu, X., & Tian, H. (2019) · Current Microbiology · doi:10.1007/s00284-019-01706-8 · Cited by 29
Saeb, A., Grundmann, S. M., Geßner, D. K., Schuchardt, S., Most, E., Wen, G., Eder, K., & Ringseis, R. (2022) · Food & Function · doi:10.1039/d1fo03920b · Cited by 29
Yao, N., Yang, Y., Li, X., Wang, Y., Guo, R., Wang, X., Li, J., Xie, Z., Li, B., & Cui, W. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.906511 · Cited by 29
The role of the gut microbiome in the development of hepatobiliary cancers
Daniel, N., Genua, F., Jenab, M., Mayén, A., Chatziioannou, A. C., Keski‐Rahkonen, P., & Hughes, D. J. (2023) · Hepatology · doi:10.1097/hep.0000000000000406 · Cited by 30
Bertani, J. P. B., Cruz, C. U., Pasqualotto, A., Longo, L., Ayres, R., Beskow, C. B., Barth, A. L., de Lima-Morales, D., Meurer, F., Guerreiro, G. T. S., et al. (2019) · Journal of the American College of Nutrition · doi:10.1080/07315724.2019.1627955 · Cited by 28
A Sweet Connection? Fructose’s Role in Hepatocellular Carcinoma
Dewdney, B., Roberts, A. A., Qiao, L., George, J., & Hebbard, L. (2020) · Biomolecules · doi:10.3390/biom10040496 · Cited by 29
The Effect of Lactobacillus fermentum ME‐3 Treatment on Glycation and Diabetes Complications
Guilbaud, A., Howsam, M., Niquet‐Léridon, C., Delguste, F., Frémont, M., Lestavel, S., Maboudou, P., Garat, A., Schraen‐Maschke, S., Onraed, B., et al. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201901018 · Cited by 26
Gut mucosal and adipose tissues as health targets of the immunomodulatory mechanisms of probiotics
Ashaolu, T. J., & Fernández‐Tomé, S. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.04.040 · Cited by 25
Won, G., Choi, S., Kang, C.-H., & Kim, G. (2021) · Microorganisms · doi:10.3390/microorganisms9061139 · Cited by 25
Sekita, A., Okazaki, Y., & Katayama, T. (2016) · Nutrition · doi:10.1016/j.nut.2016.01.003 · Cited by 25
Kawauchi, S., Horibe, S., Sasaki, N., Tanahashi, T., Mizuno, S., Hamaguchi, T., & Rikitake, Y. (2019) · Marine Drugs · doi:10.3390/md17020104 · Cited by 24
Eckel, E. F., & Ametaj, B. N. (2020) · Dairy · doi:10.3390/dairy1010006 · Cited by 27
Li, X., Zheng, P., Cao, W., Cao, Y., She, X., Yang, H., Ma, K., Wu, F., Gao, X., Fu, Y., et al. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1067367 · Cited by 24
Wang, H., Yan, Y., Yi, X., Duan, Y., Wang, J., Li, S., Luo, L., Huang, T., Inglis, B. M., Li, X., et al. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00165 · Cited by 23
Ocker, M. (2020) · World Journal of Gastroenterology · doi:10.3748/wjg.v26.i3.279 · Cited by 23
Ge, Y., Sun, H., Xu, L., Zhang, W., Lv, J., & Chen, Y. (2022) · Bioengineered · doi:10.1080/21655979.2022.2070998 · Cited by 22
RetractedThe Effect of Bioactive Aliment Compounds and Micronutrients on Non-Alcoholic Fatty Liver Disease
Munteanu, C., & Schwartz, B. (2023) · Antioxidants · doi:10.3390/antiox12040903 · Cited by 26
Lee, J. Y., An, M., Heo, H., Park, J.-Y., Lee, J., & Kang, C.-H. (2023) · Nutrients · doi:10.3390/nu15082005 · Cited by 22
Intestinally derived bacterial products stimulate development of nonalcoholic steatohepatitis
Dornas, W. C., & Lagente, V. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.01.026 · Cited by 22
Lactobacillus paracasei N1115 attenuates obesity in high‐fat diet‐induced obese mice
Sun, Y., Chen, S., Ren, F., & Li, Y. (2022) · Food Science & Nutrition · doi:10.1002/fsn3.3073 · Cited by 21
AOKI-YOSHIDA, A., Saito, S., Tsuruta, T., Ohsumi, A., Tsunoda, H., & Sonoyama, K. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.05.152 · Cited by 21
Microbiota, Liver Diseases, and Alcohol
Cassard, A., Gérard, P., & Perlemuter, G. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.bad-0007-2016 · Cited by 21
Ji, Y., Chung, Y. M., Park, S., Jeong, D., Kim, B., & Holzapfel, W. H. (2019) · PeerJ · doi:10.7717/peerj.6651 · Cited by 22
Dietary Additives and Supplements Revisited: the Fewer, the Safer for Gut and Liver Health
Golonka, R. M., Yeoh, B. S., & Vijay‐Kumar, M. (2019) · Current Pharmacology Reports · doi:10.1007/s40495-019-00187-4 · Cited by 21
Nonalcoholic fatty liver disease, diet and gut microbiota
Finelli, C., & Tarantino, G. (2014) · Europe PMC (PubMed Central) · doi:10.17877/de290r-15828 · Cited by 20
RetractedSabirin, F., Lim, S. M., Neoh, C. F., & Ramasamy, K. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.844374 · Cited by 21
Wang, Y., Wang, Z., Wan, Y., Jin, F., Shi, X., Xing, Z., Tian, B., & Li, B. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1147423 · Cited by 20
Pharmacotherapies of NAFLD: updated opportunities based on metabolic intervention
Shao, Y., Chen, S., Liu, H., & Liu, J. (2023) · Nutrition & Metabolism · doi:10.1186/s12986-023-00748-x · Cited by 20
Rani, K., Ali, S. A., Kaul, G., & Behare, P. V. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14509 · Cited by 19
Are fructophilic lactic acid bacteria (FLAB) beneficial to humans?
Dicks, L. M. T., & Endo, A. (2022) · Beneficial Microbes · doi:10.3920/bm2021.0044 · Cited by 19
Maheshwari, G., Geßner, D. K., Neuhaus, K., Most, E., Zorn, H., Eder, K., & Ringseis, R. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c06952 · Cited by 18
Kim, D., Choi, Y., Kim, S., Ha, J., Oh, H., Lee, Y., Kim, Y., Seo, Y., Park, E., Kang, J., et al. (2021) · Foods · doi:10.3390/foods10040772 · Cited by 18
Ekici, Ö., Aslan, E., Aladağ, T., Güzel, H., Korkmaz, Ö. A., Bostancı, A., Sadı, G., & Pektaş, M. B. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.13732 · Cited by 18
Diet-Regulating Microbiota and Host Immune System in Liver Disease
Eom, J. A., Kwon, G.-H., Kim, N. Y., Park, E. J., Won, S. M., Jeong, J., Ganesan, R., Gupta, H., Gebru, Y. A., Sharma, S., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126326 · Cited by 18
Li, Z., Kong, C., Mao, Y., Huang, J., Chen, H., Han, B., & Wang, L. (2023) · Liver International · doi:10.1111/liv.15512 · Cited by 17
Okazaki, Y., Sekita, A., Chiji, H., & Katô, N. (2016) · Food Science and Biotechnology · doi:10.1007/s10068-016-0112-9 · Cited by 17
Şumlu, E., Bostancı, A., Sadı, G., Alçığır, M. E., & Akar, F. (2020) · Archives of Physiology and Biochemistry · doi:10.1080/13813455.2020.1727527 · Cited by 17
Brütting, C., Bisch, M. L., Brandsch, C., Hirche, F., & Stangl, G. I. (2020) · International Journal of Food Sciences and Nutrition · doi:10.1080/09637486.2020.1773415 · Cited by 18
Wu, Y., He, X., Chen, H., Lin, Y., Zheng, C., & Zheng, B. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134305 · Cited by 16
Olotu, T., & Ferrell, J. M. (2024) · Microorganisms · doi:10.3390/microorganisms12122488 · Cited by 18
Aziz, M., Hemeda, S. A., Albadrani, G. M., Fadl, S. E., & Elgendey, F. (2023) · Scientific Reports · doi:10.1038/s41598-023-32584-7 · Cited by 16
Xu, J., Zhou, Y., Cheng, S., Zhao, Y., Yan, J., Wang, Y., Cai, W., & Jiang, L. (2023) · Metabolites · doi:10.3390/metabo13101043 · Cited by 16
Alterations of Gut Microbiome in the Patients With Severe Fever With Thrombocytopenia Syndrome
Xu, H., Wei, Y., Ma, H., Liu, Y., Zhang, Y., Hu, L., & Li, J. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02315 · Cited by 16
Okazaki, Y., Sekita, A., & Katayama, T. (2018) · Biomedical Reports · doi:10.3892/br.2018.1079 · Cited by 16
Gut microbiota in non-alcoholic fatty liver disease: Pathophysiology, diagnosis, and therapeutics
Pandey, H., Goel, P., Srinivasan, V. M., Tang, D. W. T., Wong, S. H., & Lal, D. (2025) · World Journal of Hepatology · doi:10.4254/wjh.v17.i6.106849 · Cited by 20
Zhang, Z., Zhou, H., Guan, M., Zhou, X., Liang, X., Lv, Y., Bai, L., Zhang, J., Gong, P., Liu, T., et al. (2020) · British Journal Of Nutrition · doi:10.1017/s0007114520003013 · Cited by 15
Kim, S., Joung, J. Y., Kang, D., Oh, N. S., & Yoon, Y. (2021) · International Dairy Journal · doi:10.1016/j.idairyj.2021.104997 · Cited by 15
Sun, N., Chen, S., & Li, Y. (2023) · Nutrition Research · doi:10.1016/j.nutres.2023.04.003 · Cited by 15
Ho, S. W., El-Nezami, H. S., & Shah, N. P. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103571 · Cited by 14
Schneider, A. C. R., Machado, A. B. M. P., de Assis, A. M., Hermes, D. M., Schaefer, P. G., Guizzo, R., Fracasso, L. B., de Paris, F., Meurer, F., Barth, A. L., et al. (2014) · Zebrafish · doi:10.1089/zeb.2013.0968 · Cited by 15
Vu, V., Kim, Y. M., & Cho, M.-J. (2023) · Applied Biological Chemistry · doi:10.1186/s13765-022-00755-1 · Cited by 14
Sciuto, M., & Catanzaro, R. (2023) · Acta Microbiologica et Immunologica Hungarica · doi:10.1556/030.2023.02134 · Cited by 15
Hosseini, H. M., Shirvani, H., Aghaei, F., Arabzadeh, E., & Hofmeister, M. (2022) · PubMed Central · doi:10.17179/excli2022-4791 · Cited by 13
Healthy diet intervention reverses the progression of NASH through gut microbiota modulation
Panyod, S., Wu, W., Hu, M.-Y., Huang, H., Chen, R.-A., Chen, Y., Shen, T. D., Ho, C., Liu, C., Chuang, H.-L., et al. (2023) · Microbiology Spectrum · doi:10.1128/spectrum.01868-23 · Cited by 14
Coprococcus protects against high-fat diet-induced nonalcoholic fatty liver disease in mice
Lu, K., Zhou, Y., He, L., Li, Y., Shahzad, M., & Li, D. (2024) · Journal of Applied Microbiology · doi:10.1093/jambio/lxae125 · Cited by 14
Geng, W., Zhang, Y., Yang, H. J., Zhang, J., Zhao, J., Wang, J., Jia, L., & Wang, Y. (2022) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.11820 · Cited by 14
Mazzoli, A., Porzio, A. D., Gatto, C., Crescenzo, R., Nazzaro, M., Spagnuolo, M. S., Baccigalupi, L., Ricca, E., Amoresano, A., Fontanarosa, C., et al. (2022) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2022.109247 · Cited by 14
Mendes, K. L., Lelis, D. D. F., de Freitas, D. F., da Silveira, L. H., de Paula, A. M. B., Guimarães, A. L. S., Oliveira, J. R., Andrade, M. C., Nobre, S. A. M., & Santos, S. H. S. (2021) · Molecular Biology Reports · doi:10.1007/s11033-021-06190-7 · Cited by 13
Yang, Y., Sui, J., Liao, W., Wang, S., Pan, D., Sun, G., Gao, P., Xiang, X., & Xia, H. (2025) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10646-8 · Cited by 12
Metadata
- Authors
- Ritze, Y., Bárdos, G., Claus, A., Ehrmann, V., Bergheim, I., Schwiertz, A., & Bischoff, S. C.
- Affiliations
- University of Hohenheim (DE)
- Institut für Mikroökologie (DE)
- Corresponding author
- Bischoff, Stephan C.
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-01-27
- Volume
- 9
- Issue
- 1
- Pages
- e80169
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC3903470
- OpenAlex
- W2009514456
- Semantic Scholar
- ae2ffaa03bd783feff42333b9541e6a8e65206e6
- Cited by
- 292
- References
- 51
- Citations by year
- 2026: 13 · 2025: 16 · 2024: 28 · 2023: 26 · 2022: 27 · 2021: 23 · 2020: 38 · 2019: 23 · 2018: 19 · 2017: 24 · 2016: 24 · 2015: 20 · 2014: 11
- FWCI
- 37.75
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Danone
- Bundesministerium für Bildung und Forschung (01GI0843, FKZ: 01GI0843)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Keywords
- Lactobacillus rhamnosus GG, non-alcoholic fatty liver disease, probiotics, high-fructose diet, intestinal permeability, intestinal barrier, lipopolysaccharide, gut microbiota, liver inflammation, hepatic steatosis, tight junctions, obesity
- MeSH terms
- Alanine Transaminase, Analysis of Variance, Animals, Dextrans, Fatty Liver, Fructose, Humans, Immunohistochemistry, Intestine, Small, Mice, Inbred C57BL, Permeability, DNA Primers, Caco-2 Cells, Probiotics, Mice, Lacticaseibacillus rhamnosus, Real-Time Polymerase Chain Reaction, Non-alcoholic Fatty Liver Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
