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Efficacy of Eye-Movement Desensitization and Reprocessing for Patients with Posttraumatic-Stress Disorder: A Meta-Analysis of Randomized Controlled Trials
Open accessAbstract
BACKGROUND: We performed the first meta-analysis of clinical studies by investigating the effects of eye-movement desensitization and reprocessing (EMDR) therapy on the symptoms of posttraumatic stress disorder (PTSD), depression, anxiety, and subjective distress in PTSD patients treated during the past 2 decades. METHODS: We performed a quantitative meta-analysis on the findings of 26 randomized controlled trials of EMDR therapy for PTSD published between 1991 and 2013, which were identified through the ISI Web of Science, Embase, Cochrane Library, MEDLINE, PubMed, Scopus, PsycINFO, and the Cumulative Index to Nursing and Allied Health Literature electronic databases, among which 22, 20, 16, and 11 of the studies assessed the effects of EMDR on the symptoms of PTSD, depression, anxiety, and subjective distress, respectively, as the primary clinical outcome. RESULTS: The meta-analysis revealed that the EMDR treatments significantly reduced the symptoms of PTSD (g = -0.662; 95% confidence interval (CI): -0.887 to -0.436), depression (g = -0.643; 95% CI: -0.864 to -0.422), anxiety (g = -0.640; 95% CI: -0.890 to -0.390), and subjective distress (g = -0.956; 95% CI: -1.388 to -0.525) in PTSD patients. CONCLUSION: This study confirmed that EMDR therapy significantly reduces the symptoms of PTSD, depression, anxiety, and subjective distress in PTSD patients. The subgroup analysis indicated that a treatment duration of more than 60 min per session was a major contributing factor in the amelioration of anxiety and depression, and that a therapist with experience in conducting PTSD group therapy was a major contributing factor in the reduction of PTSD symptoms.
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“Additionally, multiple studies have established EMDR as an efficacious therapeutic approach for PTSD.”
From Clinical Efficacy of Psychotherapeutic Interventions for Post-Traumatic Stress Disorder in Children and Adolescents: A Systematic Review and Analysis. (2024) · cites this paper as [71]
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Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · cited 1×
“75%, 50%, 25%, and 0% indicating high, moderate, low, and no heterogeneity, respectively [24].”
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · cited 1×
“The ORs reported in the selected RCTs were subjected to Egger’s test [21], which uses linear regression on a natural logarithmic scale to assess funnel plot asymmetry, with the level of significance set at p,0.”
MethodA Coefficient of Agreement for Nominal Scales
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“65 indicating acceptable consistency between raters and registrants [18].”
BackgroundCochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
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“The research quality of the study design, patients, outcome measures, statistical analysis, and results of the selected RCTs were assessed using the approach described by Brodaty, Green, and Koschera [19], according to the guidelines established by the Cochrane Collaboration, with a total research-quality score of six…”
MethodInfluentialBorenstein, M., Hedges, L. V., Higgins, J. P. T., & Rothstein, H. R. (2021) · doi:10.1002/9781119558378 · Cited by 9,799
Summing up: The Science of Reviewing Research
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Cognitive Therapy vs Medications in the Treatment of Moderate to Severe Depression
DeRubeis, R. J., Hollon, S. D., Amsterdam, J. D., Shelton, R. C., Young, P. R., Salomon, R. M., O’Reardon, J. P., Lovett, M. L., Gladis, M. M., Brown, L. L., et al. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.4.409 · Cited by 989 · cited 1×
“These findings are generally consistent with those of previous studies [29,36], which have reported that patients exhibited greater reductions in the symptoms of depression following cognitive therapy when treated by a therapist experienced in group therapy, compared with those treated by therapists without group-ther…”
ResultMeta‐Analysis of Psychosocial Interventions for Caregivers of People with Dementia
Brodaty, H., Green, A., & Koschera, A. (2003) · Journal of the American Geriatrics Society · doi:10.1034/j.1600-0579.2003.00210.x · Cited by 952
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“Thirteen studies [6,9,14,15,16,25,26,30,32,34,35,41,42] involved the use of blinded outcome assessors, whereas 13 studies [5,7,8,10,12,13,27,28,31,37, 38,39,40] did not report blinding.”
BackgroundProlonged Exposure versus Eye Movement Desensitization and Reprocessing (EMDR) for PTSD rape victims
ROTHBAUM, B. O., Astin, M. C., & Marsteller, F. (2005) · Journal of Traumatic Stress · doi:10.1002/jts.20069 · Cited by 458 · cited 3×
“Our findings are consistent with those of other studies on depression, which have demonstrated that EMDR group therapy significantly reduced the symptoms of depression, compared with control groups [5,7,12,30].”
BackgroundMethodResult
Flagged first, then by citations
1 of the 44 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
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Cited by
Sorted by citations
Exposure therapy for PTSD: A meta-analysis
McLean, C. P., Levy, H. C., Miller, M. L., & Tolin, D. F. (2022) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102115 · Cited by 273
Molnar, B. E., Sprang, G., Killian, K. D., Gottfried, R., Emery, V., & Bride, B. E. (2017) · Traumatology An International Journal · doi:10.1037/trm0000122 · Cited by 253
“Trauma treatment research studies point to a range of interventions, including cognitive-behavioral treatments (Bryant, Sackville, Dang, Moulds, & Guthrie, 1999), eye movement desensitization and reprocessing (EMDR; Chen et al., 2014; Shapiro & Maxfield, 2002), critical incident stress debriefing (CISD; Pack, 2013), a…”
BackgroundLandin-Romero, R., Moreno-Alcazar, A., Pagani, M., & Amann, B. L. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01395 · Cited by 188
“Since the original observation of Shapiro, over 300 studies have examined the clinical application of EMDR and several meta-analyses have shown higher or similar efficacy in PTSD compared to pharmacological or other psychological interventions (Born et al., 2006; Bisson et al., 2007, 2013; Chen et al., 2014).”
BackgroundEMDR beyond PTSD: A Systematic Literature Review
Valiente-Gómez, A., Moreno-Alcázar, A., Treen, D., Cedrón, C., Colom, F., Pérez, V., & Amann, B. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01668 · Cited by 154
Cuijpers, P., Veen, S. C. V., Sijbrandij, M., Yoder, W., & Cristea, I. A. (2020) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2019.1703801 · Cited by 159
Wilson, G., Farrell, D., Barron, I., Hutchins, J., Whybrow, D., & Kiernan, M. D. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.00923 · Cited by 145
Peeters, N., van Passel, B., & Krans, J. (2021) · British Journal of Clinical Psychology · doi:10.1111/bjc.12324 · Cited by 140
“However, studies report an average dropout rate of 16.9% (Fernandez et al., 2015) andonlymoderate effect sizes for EMDR as well (Hedges’s g = 0.662; Chen et al., 2014).”
BackgroundInfluentialMoreno‐Alcázar, A., Treen, D., Valiente-Gómez, A., Sio-Eroles, A., Pérez, V., Amann, B. L., & Raduà, J. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01750 · Cited by 111
Medically Related Post-traumatic Stress in Children and Adolescents with Congenital Heart Defects
Meentken, M. G., van Beynum, I. M., Legerstee, J. S., Helbing, W. A., & Utens, E. M. W. J. (2017) · Frontiers in Pediatrics · doi:10.3389/fped.2017.00020 · Cited by 103
(2018) · doi:10.7759/cureus.3250 · Cited by 94
Finch, J., Ford, C. E. L., Grainger, L., & Meiser‐Stedman, R. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.143 · Cited by 97
Chen, R., Gillespie, A. L., Zhao, Y., Xi, Y., Ren, Y., & McLean, L. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.00534 · Cited by 73
“The efficacy of EMDR for PTSD in trauma survivors in adults (Seidler and Wagner, 2006; Chen et al., 2014, 2015; Cusack et al., 2016) and children and adolescents (Rodenburg et al., 2009; Gillies et al., 2013; Brown et al., 2017; MorenoAlcázar et al., 2017) has been established in several systematic…”
BackgroundNovo, P., Landín-Romero, R., Guardiola-Wanden-Berghe, R., Moreno‐Alcázar, A., Valiente-Gómez, A., Lupo, W., García, F., Fernández, I., Pérez, V., & Amann, B. L. (2016) · Revista de Psiquiatría y Salud Mental · doi:10.1016/j.rpsm.2015.12.002 · Cited by 70
Yunitri, N., Kao, C.-C., Chu, H., Voss, J., Chiu, H.-L., Liu, D., Shen, S.-T. H., Chang, P.-C., Kang, X. L., & Chou, K.-R. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.01.005 · Cited by 64
Self-citationHudays, A., Gallagher, R. D., Hazazi, A., Arishi, A., & Bahari, G. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192416836 · Cited by 55
“Therefore, this meta-analysis review aimed to compare EMDR and CBT efficacy in reducing post-traumatic, anxiety, and depression symptoms among patients with PTSD.”
InfluentialThe impact of childhood sexual abuse on the outcome of intensive trauma-focused treatment for PTSD
Wagenmans, A., van Minnen, A., Sleijpen, M., & de Jongh, A. (2018) · European Journal of Psychotraumatology · doi:10.1080/20008198.2018.1430962 · Cited by 75
Tarquinio, C., Brennstuhl, M., Rydberg, J. A., Bassan, F., Peter, L., Tarquinio, C., Auxéméry, Y., Rotonda, C., & Tarquinio, P. (2020) · Issues in Mental Health Nursing · doi:10.1080/01612840.2020.1818014 · Cited by 66
“EMDR therapy’s effectiveness in the treatment of PTSD has been clearly confirmed by several randomized controlled trials and meta-analyses (Bisson & Andrex, 2007; Bradley et al., 2005; Chen et al., 2014; Cuijpers et al., 2020; Lee & Cuijpers, 2013; Maxfield & Hyer, 2002; Seidler & Wagner, 2006; Van Etten & Taylor, 199…”
MethodMeta-Analysis of Trauma-Focused Therapies for Treating the Symptoms of Posttraumatic Stress Disorder
Lenz, A. S., Haktanır, A., & Callender, K. A. (2017) · Journal of Counseling & Development · doi:10.1002/jcad.12148 · Cited by 59
Byrne, G. (2020) · Trauma Violence & Abuse · doi:10.1177/1524838020960219 · Cited by 60
Pettus‐Davis, C., Renn, T., Lacasse, J. R., & Motley, R. (2018) · Psychology of Men & Masculinity · doi:10.1037/men0000171 · Cited by 57
The EMDR Recent Birth Trauma Protocol: a pilot randomised clinical trial after traumatic childbirth
Chiorino, V., Cattaneo, M. C., Macchi, E. A., Salerno, R., Roveraro, S., Bertolucci, G. G., Mosca, F., Fumagalli, M., Cortinovis, I., Carletto, S., et al. (2019) · Psychology and Health · doi:10.1080/08870446.2019.1699088 · Cited by 66
Eye Movement Desensitization and Reprocessing and Slow Wave Sleep: A Putative Mechanism of Action
Pagani, M., Amann, B. L., Landín-Romero, R., & Carletto, S. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01935 · Cited by 65
“Furthermore, it has shown its efficacy in reducing anxiety levels in PTSD patients (Högberg et al., 2007, 2008; Bisson et al., 2013; Capezzani et al., 2013; McGuire et al., 2014; Faretta et al., 2016) and trauma-associated and psychiatric symptoms in various comorbid psychiatric diseases (Novo et al., 2014; Hase et al…”
InfluentialStress Reduction Using Bilateral Stimulation in Virtual Reality
Kamińska, D., Smółka, K., Zwoliński, G., Wiak, S., Merecz‐Kot, D., & Anbarjafari, G. (2020) · IEEE Access · doi:10.1109/access.2020.3035540 · Cited by 58
“Eye movement desentization and reprocessing (EMDR) – as it was mentioned earlier, EMDR is a relatively youngmode of psychotherapy with many studies on its usefulness for different health conditions [20], [46], [52]–[54] The theoretical framework for EMDR is Adaptive Information Processing”
BackgroundOstacoli, L., Carletto, S., Cavallo, M., Baldomir, P., Lorenzo, G. D., Fernández, I., Hase, M., Justo-Alonso, A., Lehnung, M., Migliaretti, G., et al. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.00074 · Cited by 61
Karadağ, M., Gökçen, C., & Sarp, A. S. (2019) · International Journal of Psychiatry in Clinical Practice · doi:10.1080/13651501.2019.1682171 · Cited by 53
“EMDR is shown as an effective method in the treatment of both single and multiple traumas (Chen et al., 2014) and is also effective for both old and recent traumas according to literature (Gillies et al.”
MethodResultNovo, P., Landín-Romero, R., Guardiola-Wanden-Berghe, R., Moreno‐Alcázar, A., Valiente-Gómez, A., Lupo, W., García, F., Fernández, I., Pérez, V., & Amann, B. L. (2018) · Revista de Psiquiatría y Salud Mental (English Edition) · doi:10.1016/j.rpsmen.2015.12.002 · Cited by 48
Trauma-informed care for the pediatric nurse
Goddard, A., Janicek, E., & Etcher, L. (2021) · Journal of pediatric nursing · doi:10.1016/j.pedn.2021.11.003 · Cited by 39
The effects of eye movements on emotional memories: using an objective measure of cognitive load
van Veen, S. C., Engelhard, I., & van den Hout, M. (2016) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v7.30122 · Cited by 44
Calancie, O. G., Khalid‐Khan, S., Booij, L., & Munoz, D. P. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13882 · Cited by 52
Snoek, A., Beekman, A. T. F., Dekker, J., Aarts, I., van Grootheest, G., Blankers, M., Vriend, C., van den Heuvel, O., & Thomaes, K. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02713-x · Cited by 44
“0) was estimated for the integrated EMDRDBT condition, in patients with PTSD and (sub)clinical BPD [11, 28].”
BackgroundMethodSlotema, C. W., Wilhelmus, B., Arends, L. R., & Franken, I. H. A. (2020) · European Journal of Psychotraumatology · doi:10.1080/20008198.2020.1796188 · Cited by 43
Littel, M., van den Hout, M., & Engelhard, I. M. (2016) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2016.00014 · Cited by 45
“J Behav Ther Exp Psychiatry (2008) 39(2):177–86.”
BackgroundInfluentialCarletto, S., Oliva, F., Barnato, M., Antonelli, T., Cardia, A., Mazzaferro, P., Raho, C., Ostacoli, L., Fernández, I., & Pagani, M. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.02333 · Cited by 41
Meentken, M. G., van der Mheen, M., van Beynum, I. M., Aendekerk, E. W. C., Legerstee, J. S., van der Ende, J., del Canho, R., Lindauer, R., Hillegers, M. H. J., Moll, H. A., et al. (2020) · European Journal of Psychotraumatology · doi:10.1080/20008198.2019.1705598 · Cited by 38
Gkintoni, E., Kourkoutas, E., Yotsidi, V., Stavrou, P. D., & Prinianaki, D. (2024) · Children · doi:10.3390/children11050579 · Cited by 37
“This process ultimately results in a substantial amelioration of symptoms associated with PTSD [71].”
BackgroundDouble Trouble: Treatment Considerations for Patients with Comorbid PTSD and Depression
Rosen, V., Ortiz, N. F., & Nemeroff, C. B. (2020) · Current Treatment Options in Psychiatry · doi:10.1007/s40501-020-00213-z · Cited by 36
Carletto, S., Porcaro, C., Settanta, C., Vizzari, V., Stanizzo, M. R., Oliva, F., Torta, R., Fernández, I., Moja, M. C., Pagani, M., et al. (2019) · European Journal of Psychotraumatology · doi:10.1080/20008198.2019.1600832 · Cited by 38
“Neither EMDR nor TAU were effective in reducing anxiety symptoms, in contrast with previous research on PTSD (Chen et al., 2014).”
ResultEMDR for Depression: A Meta-Analysis and Systematic Review
Sepehry, A. A., Lam, K., Sheppard, M., Guirguis‐Younger, M., & Maglio, A.-S. (2021) · Journal of EMDR Practice and Research · doi:10.1891/emdr-d-20-00038 · Cited by 41
“Evidence emerging from several meta-analyses (Benish et al., 2008; Bradley et al., 2005; Chen et al., 2015; Chen et al., 2014; Davidson & Parker, 2001; Jonas et al., 2013; Seidler & Wagner, 2006; Van Etten & Taylor, 1998) shows that EMDR is an evidence-based treatment for posttraumatic stress…”
BackgroundEMDR Therapy as a Transdiagnostic Psychotherapy
Dominguez, S. K. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780192898357.013.18 · Cited by 32
Stress Enhances the Memory-Degrading Effects of Eye Movements on Emotionally Neutral Memories
Littel, M., Remijn, M., Tinga, A. M., Engelhard, I. M., & van den Hout, M. (2017) · Clinical Psychological Science · doi:10.1177/2167702616687292 · Cited by 32
“An abundance of research demonstrates that EMDR is effective (e.g., Bisson et al., 2007; Bradley, Greene, Russ, Dutra, & Westen, 2005; Chen et al., 2014), and that this dual-task approach has significant additional value, over and above mere exposure to the traumatic memory (Lee & Cuijpers, 2013).”
Matthijssen, S. J. M. A., Verhoeven, L. C. M., van den Hout, M., & Heitland, I. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.01937 · Cited by 32
“Clinical trials and meta-analyses have demonstrated the effectiveness of EMDR in treating PTSD (for meta-analyses, see, e.g., Bradley et al., 2005; Seidler and Wagner, 2006; Bisson et al., 2007; Chen et al., 2014; Cusack et al., 2016).”
BackgroundEfficacy of EMDR Therapy for Children With PTSD: A Review of the Literature
Beer, R. (2018) · Journal of EMDR Practice and Research · doi:10.1891/1933-3196.12.4.177 · Cited by 37
Pintado, I. S., & Rasines-Laudes, P. (2023) · Psicothema · doi:10.7334/psicothema2022.309 · Cited by 34
“Similarly, effect size reported for depressive symptoms was small and therefore differed from the results found in other meta-analyses ( Chen et al., 2014; Cusack et al., 2016).”
InfluentialWhitehouse, J. (2019) · European Journal of Trauma & Dissociation · doi:10.1016/j.ejtd.2019.03.002 · Cited by 27
Vogel, A., & Rosner, R. (2020) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-019-00305-0 · Cited by 25
Finch, J., Ford, C. E. L., Lombardo, C., & Meiser‐Stedman, R. (2020) · European Journal of Psychotraumatology · doi:10.1080/20008198.2020.1815281 · Cited by 24
“In addition to TF-CBT, promising evidence has been found for interventions including Eye Movement Desensitisation and Reprocessing (EMDR; Chen et al., 2014) and Narrative Exposure Therapy (NET; Robjant & Fazel, 2010).”
BackgroundJung, W. H., Chang, K. J., & Kim, N. H. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.03.003 · Cited by 26
“EMDR is an evidence-based effective psychotherapy and currently recommended as the treatment of choice for trauma by international guidelines (Bradley et al., 2005; Ponniah and Hollon, 2009; Bisson et al., 2013; World Health Organization, 2013; Chen et al., 2014; Cusack et al., 2016).”
BackgroundManaging women‐specific bleeding in inherited bleeding disorders: A multidisciplinary approach
Mauser‐Bunschoten, E. P., Kadir, R. A., Laan, E. T. M., Elfvinge, P., Haverman, L., Teela, L., Degenaar-Dujardin, M. E. L., van de Putte, D. E. F., d’Oiron, R., & van Galen, K. P. M. (2020) · Haemophilia · doi:10.1111/hae.14221 · Cited by 24
Köhler, K., Eggert, P., Lorenz, S., Herr, K., Willmund, G., Zimmermann, P. L., & Alliger‐Horn, C. (2017) · Military Medicine · doi:10.7205/milmed-d-16-00307 · Cited by 23
Littel, M., Kenemans, J. L., Baas, J. M. P., Logemann, H. N. A., Rijken, N., Remijn, M., Hassink, R. J., Engelhard, I. M., & van den Hout, M. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.03.012 · Cited by 23
Yan, S., Shan, Y., Zhong, S., Miao, H., Luo, Y., Ran, H., & Jia, Y. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.700458 · Cited by 26
Lazzaroni, E., Invernizzi, R., Fogliato, E., Pagani, M., & Maslovaric, G. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.701381 · Cited by 38
“The results point to a post-intervention reduction in anxiety levels and post-traumatic symptomatology in line with previous studies (de Roos et al., 2011; Chen et al., 2014; Wilson et al., 2018; Yunitri et al., 2020).”
ResultLittel, M., van Schie, K., & van den Hout, M. (2017) · European Journal of Psychotraumatology · doi:10.1080/20008198.2017.1328954 · Cited by 23
“Eye movement desensitization and reprocessing (EMDR) has been extensively validated as an effective psychological treatment for posttraumatic stress disorder (PTSD; Bisson et al., 2007; Bradley, Greene, Russ, Dutra, & Westen, 2005; Chen et al., 2014).”
Szpringer, M., Oledzka, M., & Amann, B. L. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.00785 · Cited by 22
“The efficacy of EMDR for PTSD has undergone the scrutiny of various metaanalyses (Van Etten and Taylor, 1998; Davidson and Parker, 2001; Bradley et al., 2005; Seidler and Wagner, 2006; Bisson and Andrew, 2007; Benish et al., 2008; Jonas et al., 2013; Chen et al., 2014, 2015; Cusack et al., 2016).”
BackgroundMacarenco, M.-M., Opariuc‐Dan, C., & Nedelcea, C. (2021) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2021.105322 · Cited by 24
Using collaboration networks to identify authorship dependence in meta‐analysis results
Moulin, T. C., & Amaral, O. B. (2020) · Research Synthesis Methods · doi:10.1002/jrsm.1430 · Cited by 22
Zucker, N. L., Strauss, G. P., Smyth, J. M., Scherf, K. S., Brotman, M. A., Boyd, R. C., Choi, J., Davila, M. I., Ajilore, O., Gunning, F. M., et al. (2023) · Perspectives on Psychological Science · doi:10.1177/17456916231197980 · Cited by 20
“Take, for example, eye movement desensitization and reprocessing (EMDR), a treatment that has shown efficacy in reducing symptoms of posttraumatic stress disorder across numerous randomized controlled trials (for review, see Chen et al., 2014).”
Vecchi, T., & Gatti, D. (2020) · The MIT Press eBooks · doi:10.7551/mitpress/13543.001.0001 · Cited by 31
Morris, H., Hatzikiriakidis, K., Savaglio, M., Dwyer, J., Lewis, C., Miller, R., & Skouteris, H. (2022) · Journal of Traumatic Stress · doi:10.1002/jts.22792 · Cited by 22
Bosmans, M. W. G., van der Knaap, L. M., & van der Velden, P. G. (2015) · Psychological Trauma Theory Research Practice and Policy · doi:10.1037/tra0000088 · Cited by 19
“It is expected that, given the proven effectiveness of treatment (Bisson, Roberts, Andrew, Cooper, & Lewis, 2013; Chen et al., 2014; Bradley, Greene, Russ, Dutra, & Westen, 2005; Ehring et al., 2014), most patients will recover or at least experience a significant reduction in symptom levels.”
BackgroundA Clinician's Guide to the Efficacy of EMDR Therapy
Maxfield, L. (2019) · Journal of EMDR Practice and Research · doi:10.1891/1933-3196.13.4.239 · Cited by 19
Using EMDR Therapy to Treat Clients Remotely
Fisher, N. (2021) · Journal of EMDR Practice and Research · doi:10.1891/emdr-d-20-00041 · Cited by 19
“Several meta-analyses and reviews have shown that EMDR is an effective treatment for PTSD in adults (Bisson et al., 2013; Bradley et al., 2005; Chen et al., 2015; Chen et al., 2014 ; Khan et al., 2018; Novo Navarro et al., 2018; Seidler & Wagner, 2006) and children (Barron et al.”
BackgroundKaptan, S. K., Kaya, Z. M., & Akan, A. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1336569 · Cited by 19
Carletto, S., Borsato, T., & Pagani, M. (2017) · Frontiers in Psychology · doi:10.3389/fpsyg.2017.02050 · Cited by 22
“Eye Movement Desensitization and Reprocessing (EMDR) was initially proposed in the late 80’s by Francine Shapiro (Shapiro, 1989) and it’s now a well-established psychological treatment for PTSD (Bradley et al., 2005; Chen et al., 2014).”
BackgroundMatthijssen, S. J. M. A., van Schie, K., & van den Hout, M. (2018) · Cognition & Emotion · doi:10.1080/02699931.2018.1547271 · Cited by 20
“Eye movement desensitization and reprocessing (EMDR) therapy is an evidence-based therapy for post-traumatic stress disorder (PTSD; e.g. Bisson et al., 2007; Bradley, Greene, Russ, Dutra, & Westen, 2005; Chen et al., 2014; Lee & Cuijpers, 2013; Seidler & Wagner, 2006).”
BackgroundA Mixed Methods Evaluation of EMDR for Treating Female Survivors of Sexual and Domestic Violence
Schwarz, J. E., Baber, D., Barter, A., & Dorfman, K. (2019) · Counseling Outcome Research and Evaluation · doi:10.1080/21501378.2018.1561146 · Cited by 18
“Large effect sizes were found across each measure, indicating EMDR produced stronger change in these participants’ mental health than found in recent studies with moderate effect sizes (Chen et al., 2014; Moreno-Alc azar et al., 2017).”
BackgroundResultInfluentialOpheim, E., Andersen, P. N., Jakobsen, M., Aasen, B., & Kvaal, K. S. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.01558 · Cited by 20
Lenferink, L., de Keijser, J., Smid, G., & Boelen, P. (2020) · Traumatology An International Journal · doi:10.1037/trm0000253 · Cited by 19
Cotter, P., Meysner, L., & Lee, C. W. (2017) · European Journal of Psychotraumatology · doi:10.1080/20008198.2017.1375838 · Cited by 17
“This therapeutic process has been found to result in a reduction in Posttraumatic Stress Disorder (PTSD) symptoms, such as the frequency of intrusive symptoms (Chen et al., 2014), and a reduction in the vividness and emotional intensity of distressing memories (Lee & Cuijpers, 2013).”
Jiménez, G., Becker, Y., Varela, C., García, P., Nuño, M. A., Pérez, M. C., Osorio, A., Jarero, I., & Givaudan, M. (2020) · American Journal of Applied Psychology · doi:10.11648/j.ajap.20200902.12 · Cited by 13
Adaptive Information Processing Theory: Origins, Principles, Applications, and Evidence
Hill, M. D. (2020) · Journal of Evidence-Based Social Work · doi:10.1080/26408066.2020.1748155 · Cited by 24
Saccenti, D., Lodi, L., Moro, A. S., Scaini, S., Forresi, B., Lamanna, J., & Ferro, M. (2024) · Brain Sciences · doi:10.3390/brainsci14030210 · Cited by 17
Buys, M. E. (2025) · Clinical Psychologist · doi:10.1080/13284207.2025.2533127 · Cited by 17
Involvement of the cerebellum in EMDR efficiency: a metabolic connectivity PET study in PTSD
Verger, A., Rousseau, P., Malbos, É., Chawki, M. B., Nicolas, F., Lançon, C., Khalfa, S., & Guedj, É. (2020) · European Journal of Psychotraumatology · doi:10.1080/20008198.2020.1767986 · Cited by 20
“Eye movement desensitization and reprocessing (EMDR) is now a well-established treatment for PTSD (Chen et al., 2014).”
BackgroundMeentken, M. G., van der Mheen, M., van Beynum, I. M., Aendekerk, E. W. C., Legerstee, J. S., van der Ende, J., del Canho, R., Lindauer, R., Hillegers, M. H. J., Helbing, W. A., et al. (2021) · European Journal of Cardiovascular Nursing · doi:10.1093/eurjcn/zvaa006 · Cited by 15
“Meta-analyses show that eye movement desensitization and reprocessing (EMDR) is an effective psychotherapy to reduce PTSD symptoms in adults.(18,19) EMDR has also been found to be effective in reducing depression, anxiety, and sleep problems, and in improving quality of life in adults.”
BackgroundSusanty, E., Sijbrandij, M., Srisayekti, W., Suparman, Y., & Huizink, A. C. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.845520 · Cited by 14
Matthijssen, S. J. M. A., Heitland, I., Verhoeven, L. C. M., & van den Hout, M. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2019.00637 · Cited by 16
Strelchuk, D., Turner, K. M., Smith, S., Bisson, J. I., Wiles, N., & Zammit, S. (2023) · European Journal of Psychotraumatology · doi:10.1080/20008066.2023.2281182 · Cited by 18
“For example, comparisons of EMDR with waiting list and usual care have consistently shown that EMDR is superior to these in treating PTSD (Bisson JI et al., 2013; Chen et al., 2014; Roberts et al., 2019).”
Matthijssen, S., van Beerschoten, L. M., de Jongh, A., Klugkist, I., & van den Hout, M. (2019) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2018.11.006 · Cited by 16
The Effectiveness of EMDR for Medically Unexplained Symptoms: A Systematic Literature Review
Staton, A., Wilde, S., & Dawson, D. L. (2022) · Journal of EMDR Practice and Research · doi:10.1891/emdr-2022-0017 · Cited by 13
Conijn, T., de Roos, C., Vreugdenhil, H. J. I., van Dijk‐Lokkart, E. M., Wijburg, F. A., & Haverman, L. (2022) · Orphanet Journal of Rare Diseases · doi:10.1186/s13023-022-02500-9 · Cited by 13
Suárez, N. A., Pérez, J. M., Redolar-Ripoll, E., Hogg, B., Gardoki-Souto, I., García-Guerrero, F., Cabrera‐Jaime, S., Bernal, D. S., Amann, B. L., & Moreno‐Alcázar, A. (2020) · Journal of EMDR Practice and Research · doi:10.1891/emdr-d-20-00004 · Cited by 13
Rhodes, J. R., Tedeschi, R. G., Moore, B. A., Alldredge, C. T., & Elkins, G. R. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1322837 · Cited by 23
Shipley, G., Wilde, S., & Hudson, M. (2021) · European Journal of Trauma & Dissociation · doi:10.1016/j.ejtd.2021.100226 · Cited by 11
Akute und posttraumatische Belastungsstörung
Kapfhammer, H. (2017) · Springer eBooks · doi:10.1007/978-3-662-49295-6_71 · Cited by 11
Eye movement desensitization reprocessing as a treatment for PTSD in conflict-affected areas.
Wippich, A., Howatson, G., Allen, G., Farrell, D. P., Kiernan, M. D., & Scott, A. (2023) · Psychological Trauma Theory Research Practice and Policy · doi:10.1037/tra0001430 · Cited by 11
EMDR in Older Adults With Posttraumatic Stress Disorder
Gielkens, E. M. J., Vink, M., Sobczak, S., Rosowsky, E., & van Alphen, B. (2018) · Journal of EMDR Practice and Research · doi:10.1891/1933-3196.12.3.132 · Cited by 11
Amano, T., & Toichi, M. (2016) · Scientific Reports · doi:10.1038/srep34610 · Cited by 15
EMDR als psychotherapeutischer Ansatz in der Schmerztherapie
Wicking, M., Maier, C., Tesarz, J., & Bernardy, K. (2017) · Der Schmerz · doi:10.1007/s00482-017-0231-0 · Cited by 11
Meentken, M. G., van Beynum, I. M., Aendekerk, E. W. C., Legerstee, J. S., Marroun, H. E., van der Ende, J., Lindauer, R., Hillegers, M. H. J., Moll, H. A., Helbing, W. A., et al. (2018) · European Journal of Psychotraumatology · doi:10.1080/20008198.2018.1536287 · Cited by 10
Hendrix, Y. M. G. A., van Dongen, K. S. M., de Jongh, A., & van Pampus, M. G. (2021) · Trials · doi:10.1186/s13063-021-05545-6 · Cited by 13
A HYPOTHETICAL MECHANISM OF ACTION OF EMDR: THE ROLE OF SLOW WAVE SLEEP
Pagani, M., & Carletto, S. (2017) · Institutional Research Information System University of Turin (University of Turin) · Cited by 10
A FLASH OF HOPE: Eye Movement Desensitization and Reprocessing (EMDR) Therapy.
Gainer, D. M., Alam, S., Alam, H., & Redding, H. (2020) · Europe PMC (PubMed Central) · Cited by 9
Treating COVID-19 patients with EMDR: A pilot study
Brennstuhl, M., Tarquinio, P., Rydberg, J. A., Tarquinio, C., Peter, L., Rotonda, C., & Tarquinio, C. (2022) · European Journal of Trauma & Dissociation · doi:10.1016/j.ejtd.2022.100276 · Cited by 10
“From a clinical perspective we know that the psychotraumatic spectrum in such situations is often much broader than PTSD alone.”
InfluentialAranda, B. D. E., Ronquillo, N. M., & Calvillo, M. E. N. (2015) · Journal of EMDR Practice and Research · doi:10.1891/1933-3196.9.4.174 · Cited by 13
Gardoki-Souto, I., de la Torre, O. M., Hogg, B., Redolar-Ripoll, E., Valiente-Gómez, A., Martínez-Sadurní, L., Blanch, J. M., Lupo, W., Pérez, V., Raduà, J., et al. (2021) · Trials · doi:10.1186/s13063-021-05042-w · Cited by 9
Straub, R. K., & Powers, C. M. (2021) · Healthcare · doi:10.3390/healthcare9111537 · Cited by 8
“Systematic reviews and meta-analyses have shown that EFT and EMDR are both effective for the treatment of depression [33,34], post-traumatic stress disorder (PTSD) [34,35], and anxiety [34,36].”
BackgroundPediatric seizure-related posttraumatic stress and anxiety symptoms treated with EMDR: a case series
Dautovic, E., de Roos, C., van Rood, Y. R., Dommerholt, A. H., & Rodenburg, R. (2016) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v7.30123 · Cited by 9
“Meta-analytic results showed that EMDR is an effective treatment for PTSD in adults and children (Chen et al., 2014; Rodenburg, Benjamin, de Roos, Meijer, & Stams, 2009).”
Eye movement desensitisation and reprocessing: part 1 – theory, procedure and use in PTSD
Udo, I. I., Javinsky, T.-R., & Awani, T. (2022) · BJPsych Advances · doi:10.1192/bja.2022.32 · Cited by 8
“Another meta-analysis, by Chen et al (2014), considered studies reported between 1991 and 2013 that investigated the effects of EMDR not only on symptoms of PTSD but also on symptoms of depression and anxiety.”
Kip, A., Ritter, L., Hoppen, T. H., Papola, D., Ostuzzi, G., Barbui, C., & Nexhmedin Morina, B. (2025) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2025.103017 · Cited by 12
Metadata
- Authors
- Chen, Y.-R., Hung, K.-W., Tsai, J.-C., Chu, H., Chung, M.-H., Chen, S.-R., Liao, Y.-M., Ou, K.-L., Chang, Y.-C., & Chou, K.-R.
- Affiliations
- Taoyuan Armed Forces General Hospital (TW)
- Yuan's General Hospital (TW)
- Taipei Medical University-Shuang Ho Hospital (TW)
- Tri-Service General Hospital (TW)
- Taipei Medical University (TW)
- Tamkang University (TW)
- Taipei Medical University Hospital (TW)
- Corresponding author
- Chou, Kuei-Ru
- Venue
- PLoS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2014-08-07
- Volume
- 9
- Issue
- 8
- Pages
- e103676
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4125321
- OpenAlex
- W2069381491
- Cited by
- 222
- References
- 44
- Citations by year
- 2026: 17 · 2025: 23 · 2024: 19 · 2023: 18 · 2022: 14 · 2021: 34 · 2020: 25 · 2019: 17 · 2018: 20 · 2017: 18 · 2016: 11 · 2015: 6
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- PLoS ONE (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Taipei Medical University Repository (submittedVersion)
- Tamkang University Institutional Repository (TKUIR) (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Science Council
- Topics
- Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- EMDR, post-traumatic stress disorder, depression, anxiety, subjective distress, treatment duration, therapist experience, group therapy, psychotherapy efficacy
- MeSH terms
- Adult, Humans, Middle Aged, Regression Analysis, Stress Disorders, Post-Traumatic, Randomized Controlled Trials as Topic, Treatment Outcome, Eye Movement Desensitization Reprocessing
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