Leucocyte Telomere Length and Risk of Type 2 Diabetes Mellitus: New Prospective Cohort Study and Literature-Based Meta-Analysis

Willeit, Peter; Raschenberger, Julia; Heydon, Emma E.; Tsimikas, Sotirios; Haun, Margot; Mayr, Agnes; Weger, Siegfried; Witztum, Joseph L.; Butterworth, Adam S.; Willeit, Johann; Kronenberg, Florian; Kiechl, Stefan

doi:10.1371/journal.pone.0112483

Leucocyte Telomere Length and Risk of Type 2 Diabetes Mellitus: New Prospective Cohort Study and Literature-Based Meta-Analysis

Background Short telomeres have been linked to various age-related diseases. We aimed to assess the association of telomere length with incident type 2 diabetes mellitus (T2DM) in prospective cohort studies. Methods Leucocyte relative telomere length (RTL) was measured using quantitative polymera…