Incidence and Estimated Prevalence of Endometriosis and Adenomyosis in Northeast Italy: A Data Linkage Study
Open accessAbstract
Despite being quite frequent and having serious implications in terms of symptomatology and fertility, data on incidence and prevalence of endometriosis and adenomyosis following gold standard definitions are dramatically lacking. The average time from onset of symptoms to diagnosis in industrialized countries still ranges from five to ten years. Using the regional centralized data linkage system, we calculated incidence and prevalence of endometriosis and adenomyosis in the female population of Friuli Venezia Giulia region, Italy, for the years 2011-2013. Cases were defined as new diagnoses from hospital discharge records, following procedures allowing direct visualization for endometriosis and hysterectomy for adenomyosis, with or without histological confirmation. Diagnoses were considered "new" after verifying women had not been diagnosed in the previous ten years. Incidence of endometriosis and adenomyosis in women aged 15-50 years is 0.14%. Prevalence, estimated from incidence, is 2.00%. Adenomyosis, representing 28% of all diagnoses, becomes increasingly prevalent after the age of 50 years. Our results shows how the study of both endometriosis and adenomyosis should not be limited to women of premenopausal age. Further efforts are needed to sensitize women and health professional, and to find new data linkage possibilities to identify undiagnosed cases.
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In a population-based study in Northeast Italy, estimated prevalence of adenomyosis is 0.18%, lower than endometriosis at 1.14%.
“In a rare population-based study, the estimated prevalence of adenomyosis in Northeast Italy is reported to be 0.18%, much lower than that of endometriosis (1.14%) [17].”
From The Pathogenesis of Adenomyosis vis-à-vis Endometriosis (2020) · cites this paper as [17]
Age-specific incidence of adenomyosis peaks at 46-50 years.
“The age-specific incidence of adenomyosis is very different from that of endometriosis, reaching its peak at the age interval of 46–50 years [17].”
From The Pathogenesis of Adenomyosis vis-à-vis Endometriosis (2020) · cites this paper as [17]
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ESHRE guideline: management of women with endometriosis
Dunselman, G. A. J., Vermeulen, N., Becker, C., Calhaz-Jorge, C., D'Hooghe, T., De Bie, B., Heikinheimo, O., Horne, A. W., Kiesel, L., Nap, A., et al. (2014) · Human Reproduction · doi:10.1093/humrep/det457 · Cited by 2,211 · see citing works
Eskenazi, B., & Warner, M. L. (1997) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(05)70302-8 · Cited by 1,617 · see citing works
Nnoaham, K. E., Hummelshoj, L., Webster, P., d’Hooghe, T., de Cicco Nardone, F., de Cicco Nardone, C., Jenkinson, C., Kennedy, S. H., & Zondervan, K. T. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.05.090 · Cited by 1,584 · see citing works
ESHRE guideline for the diagnosis and treatment of endometriosis
Kennedy, S., Bergqvist, A., Chapron, C., D’Hooghe, T., Dunselman, G., Greb, R., Hummelshoj, L., Prentice, A., & Saridogan, E. (2005) · Human Reproduction · doi:10.1093/humrep/dei135 · Cited by 1,584 · see citing works
Diagnostic delay for endometriosis in Austria and Germany: causes and possible consequences
Hudelist, G., Fritzer, N., Thomas, A. E., Niehues, C., Oppelt, P., Haas, D., Tammaa, A., & Sälzer, H. (2012) · Human Reproduction · doi:10.1093/humrep/des316 · Cited by 493 · see citing works
Ballard, K., Seaman, H., De Vries, C., & Wright, J. (2008) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2008.01878.x · Cited by 457 · see citing works
Arruda, M. S. (2003) · Human Reproduction · doi:10.1093/humrep/deg136 · Cited by 373 · see citing works
A systematic review of the accuracy of ultrasound in the diagnosis of endometriosis
Moore, J. A., Copley, S. J., Morris, J., Lindsell, D. R., Golding, S. J., & Kennedy, S. (2002) · Ultrasound in Obstetrics and Gynecology · doi:10.1046/j.1469-0705.2002.00862.x · Cited by 244 · see citing works
Champaneria, R., Abedin, P., DANIELS, J. P., Balogun, M., & Khan, K. S. (2010) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349.2010.512061 · Cited by 240 · see citing works
Epidemiology of endometriosis in women attending family planning clinics
Vessey, M. P., Villard-Mackintosh, L., & Painter, R. (1993) · BMJ · doi:10.1136/bmj.306.6871.182 · Cited by 217 · see citing works
Endometriosis: A Disease That Remains Enigmatic
Acién, P., & Velasco, I. (2013) · ISRN Obstetrics and Gynecology · doi:10.1155/2013/242149 · Cited by 182 · see citing works
INCIDENCE OF PELVIC ENDOMETRIOSIS IN ROCHESTER, MINNESOTA, 1970–1979
Houston, D. E., Noller, K. L., Melton, L. J., Selwyn, B. J., & Hardy, R. J. (1987) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a114634 · Cited by 167 · see citing works
Abbas, S., Ihle, P., Köster, I., & Schübert, I. (2011) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2011.09.041 · Cited by 164 · see citing works
Epidemiology of endometriosis in a Norwegian county
Moen, M. H., & Schei, B. (1997) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349709024584 · Cited by 154 · see citing works
Endometriosis: a premenopausal disease? Age pattern in 42,079 patients with endometriosis
Haas, D., Chvátal, R., Reichert, B., Renner, S. P., Shebl, O. J., Binder, H., Wurm, P., & Oppelt, P. (2012) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-012-2361-z · Cited by 149 · see citing works
Pelvic Endometriosis Diagnosed in an Entire Nation Over 20 Years
Gylfason, J. T., Kristjansson, K. A., Sverrisdottir, G., Jónsdóttir, K., Rafnsson, V., & Geirsson, R. T. (2010) · American Journal of Epidemiology · doi:10.1093/aje/kwq143 · Cited by 144 · see citing works
Incidence and characterization of diagnosed endometriosis in a geographically defined population
Leibson, C. L., Good, A. E., Hass, S., Ransom, J. E., Yawn, B. P., O’Fallon, W. M., & Melton, L. J. (2004) · Fertility and Sterility · doi:10.1016/j.fertnstert.2004.01.037 · Cited by 117 · see citing works
Prevalence of newly diagnosed endometriosis in women attending the general practitioner
Ferrero, S., Arena, E., Morando, A., & Remorgida, V. (2010) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2010.03.039 · Cited by 110 · see citing works
Burkman, R. T. (2012) · JAMA · doi:10.1001/jama.308.16.1693 · Cited by 100 · see citing works
Adenomyosis: a life-cycle approach
Benagiano, G., Brosens, I. A., & Habiba, M. A. (2014) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2014.11.005 · Cited by 84 · see citing works
Guo, S., & Wang, Y. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.04.040 · Cited by 59 · see citing works
The effect of hormones on endometriosis development.
Barbosa, C. P., de Souza, Â. M. B., Bianco, B. A. V., & Christofolini, D. M. (2011) · PubMed · Cited by 54 · see citing works
Adenomyosis: A Challenge in Clinical Gynecology
Cockerham, A. Z. (2012) · Journal of Midwifery & Women s Health · doi:10.1111/j.1542-2011.2011.00117.x · Cited by 31 · see citing works
Eggert, J., Li, X., & Sundquist, K. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.07.1345 · Cited by 29 · see citing works
Endometriosis in postmenopausal women without previous hormonal therapy: report of three cases
Rosa-e-Silva, J. C., de Carvalho, B. R., Barbosa, H. D. F., Poli‐Neto, O. B., Rosa-e-Silva, A. C. J. S., Candido-dos-Reis, F. J., & Nogueira, A. (2008) · Climacteric · doi:10.1080/13697130802490256 · Cited by 22 · see citing works
Endometriosis in a Postmenopausal Woman on Hormonal Replacement Therapy
Jeon, D.-S., Kim, T., Lee, H., & Byun, D. W. (2013) · Journal of Menopausal Medicine · doi:10.6118/jmm.2013.19.3.151 · Cited by 21 · see citing works
Borghese, B., Chartier, M., de Souza, C. A. B., Santulli, P., Lafay-Pillet, M.-C., de Ziegler, D., & Chapron, C. (2014) · BioMed Research International · doi:10.1155/2014/618964 · Cited by 16 · see citing works
Spatial Analysis of the Distribution of Endometriosis in Northwestern Italy
Migliaretti, G., Deltetto, F., Delpiano, E. M., Bonino, L., Berchialla, P., Dalmasso, P., Cavallo, F., & Camanni, M. (2011) · Gynecologic and Obstetric Investigation · doi:10.1159/000332367 · Cited by 14 · see citing works
The immunoprofile of interstitial Cajal cells within adenomyosis/endometriosis lesions.
Draghici, I. M., Drăghici, L., Cojocaru, M., Gorgan, C.-L., & Vrabie, C. D. (2015) · PubMed · Cited by 7 · see citing works
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- [13]Legge regionale 11 ottobre 2012, n. 18. Disposizioni per la tutela delle donne affette da endometriosi. Bollettino Ufficiale Regionale Friuli Venezia Giulia. 2012; 42: 11– 13. Available: http://bur.regione.fvg.it/newbur/downloadPDF?doc=0&name=2012/10/17/BUR%2042_noLEGAL.pdf.
- [17]Marwan H, Benagiano G, editors. Uterine Adenomyosis. Cham: Springer International Publishing AG; 2015.
Cited by
Sorted by citations
Clinical diagnosis of endometriosis: a call to action
Agarwal, S. K., Chapron, C., Giudice, L. C., Laufer, M. R., Leyland, N., Missmer, S. A., Singh, S. S., & Taylor, H. S. (2019) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2018.12.039 · Cited by 843 · see citing works
Eisenberg, V. H., Weil, C., Chodick, G., & Shalev, V. (2017) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.14711 · Cited by 337 · see citing works
Ata, B., Yıldız, Ş., Türkgeldi, E., Pérez‐Brocal, V., Dinleyici, E. Ç., Moyá, A., & Urman, B. (2019) · Scientific Reports · doi:10.1038/s41598-019-39700-6 · Cited by 294 · see citing works
Prevalence and incidence of endometriosis in Australian women: a data linkage cohort study
Rowlands, I., Abbott, J., Montgomery, G., Hockey, R., Rogers, P., & Mishra, G. (2021) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.16447 · Cited by 230 · see citing works
Upson, K., & Missmer, S. A. (2020) · Seminars in Reproductive Medicine · doi:10.1055/s-0040-1718920 · Cited by 254 · see citing works
Lalani, S., Choudhry, A. J., Firth, B., Bacal, V, Walker, M., Wen, S. W., Singh, S., Amath, A., Hodge, M., & Chen, I. (2018) · Human Reproduction · doi:10.1093/humrep/dey269 · Cited by 206 · see citing works
Adenomyosis incidence, prevalence and treatment: United States population-based study 2006–2015
Yu, O., Schulze-Rath, R., Grafton, J., Hansen, K., Scholes, D., & Reed, S. D. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.01.016 · Cited by 200 · see citing works
The Pathogenesis of Adenomyosis vis-à-vis Endometriosis
Guo, S.-W. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020485 · Cited by 165 · see citing works
“The age-specific incidence of adenomyosis is very different from that of endometriosis, reaching its peak at the age interval of 46– 50 years [17].”
BackgroundIs Endometriosis More Common and More Severe Than It Was 30 Years Ago?
Ghiasi, M., Kulkarni, M. T., & Missmer, S. A. (2019) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2019.11.018 · Cited by 132 · see citing works
Endometriosis: current challenges in modeling a multifactorial disease of unknown etiology
Malvezzi, H., Marengo, E. B., Podgaec, S., & Piccinato, C. D. A. (2020) · Journal of Translational Medicine · doi:10.1186/s12967-020-02471-0 · Cited by 110 · see citing works
Systematic Review and Meta-Analysis of Incidence and Prevalence of Endometriosis
Sarría‐Santamera, A., Orazumbekova, B., Terzić, M., Issanov, A., Chaowen, C., & Asúnsolo, Á. (2020) · Healthcare · doi:10.3390/healthcare9010029 · Cited by 110 · see citing works
Endometriosis: Perspective, lights, and shadows of etiology
Asghari, S., Valizadeh, A., Maleki, L. A., Nouri, M., & Yousefi, M. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.06.109 · Cited by 110 · see citing works
The Prevalence of Endometriosis in Adolescents with Pelvic Pain: A Systematic Review
Hirsch, M., Dhillon‐Smith, R. K., Cutner, A. S., Yap, M., & Creighton, S. (2020) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2020.07.011 · Cited by 104 · see citing works
Christ, J. P., Yu, O., Schulze‐Rath, R., Grafton, J. R., Hansen, K. E., & Reed, S. D. (2021) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2021.06.067 · Cited by 91 · see citing works
Devesa-Peiró, A., Sebastián-León, P., Párraga-Leo, A., Pellicer, A., & Díaz-Gimeno, P. (2022) · Human Reproduction · doi:10.1093/humrep/deac010 · Cited by 88 · see citing works
Endometriosis: A Comprehensive Review
Arafah, M., Rashid, S., & Akhtar, M. (2020) · Advances in Anatomic Pathology · doi:10.1097/pap.0000000000000288 · Cited by 82 · see citing works
Psychiatric comorbidity among women with endometriosis: nationwide cohort study in Sweden
Gao, M., Koupil, I., Sjöqvist, H., Karlsson, H., Lalitkumar, S., Dalman, C., & Kosidou, K. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.02.033 · Cited by 79 · see citing works
Pathogenesis of Human Adenomyosis: Current Understanding and Its Association with Infertility
Khan, K. N., Fujishita, A., & Mori, T. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11144057 · Cited by 74 · see citing works
Ovarian stimulation and endometriosis progression or recurrence: a systematic review
Somigliana, E., Viganò, P., Benaglia, L., Busnelli, A., Paffoni, A., & Vercellini, P. (2019) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2018.11.021 · Cited by 69 · see citing works
Is Stress a Cause or a Consequence of Endometriosis?
dos Reis, F. M., Coutinho, L. M., Vannuccini, S., Luisi, S. V., & Petraglia, F. (2020) · Reproductive Sciences · doi:10.1007/s43032-019-00053-0 · Cited by 70 · see citing works
Experiences of health after dietary changes in endometriosis: a qualitative interview study
Karlsson, J. V., Patel, H., & Premberg, Å. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-032321 · Cited by 62 · see citing works
Irritable bowel syndrome and endometriosis: New insights for old diseases
Viganò, D., Zara, F., & Usai, P. (2017) · Digestive and Liver Disease · doi:10.1016/j.dld.2017.12.017 · Cited by 57 · see citing works
Factors and Regional Differences Associated with Endometriosis: A Multi-Country, Case–Control Study
Chapron, C., Lang, J., Leng, J., Zhou, Y., Zhang, X., Xue, M., Popov, А. А., Romanov, V., Maisonobe, P., & Cabri, P. (2016) · Advances in Therapy · doi:10.1007/s12325-016-0366-x · Cited by 58 · see citing works
Real world data on symptomology and diagnostic approaches of 27,840 women living with endometriosis
Becker, K., Heinemann, K., Imthurn, B., Marions, L., Moehner, S., Gerlinger, C., Serrani, M., & Faustmann, T. A. (2021) · Scientific Reports · doi:10.1038/s41598-021-99681-3 · Cited by 56 · see citing works
Assessing the true prevalence of endometriosis: A narrative review of literature data
Harder, C., Velho, R. V., Brandes, I., Sehouli, J., & Mechsner, S. (2024) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.15756 · Cited by 61 · see citing works
Global, regional, and national endometriosis trends from 1990 to 2017
Zhang, S., Gong, T., Wang, H., Zhao, Y., & Wu, Q. (2020) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14468 · Cited by 48 · see citing works
Gandini, S., Lazzeroni, M., Peccatori, F. A., Bendinelli, B., Saieva, C., Palli, D., Masala, G., & Caini, S. (2019) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2018.12.009 · Cited by 46 · see citing works
The frequency of endometriosis in the general and selected populations: A systematic review
Parazzini, F., Roncella, E., Cipriani, S., Trojano, G., Barbera, V., Herranz‐Blanco, B., & Colli, E. (2020) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.1177/2284026520933141 · Cited by 46 · see citing works
Heinemann, K., Imthurn, B., Marions, L., Gerlinger, C., Becker, K., Moehner, S., & Faustmann, T. A. (2020) · Advances in Therapy · doi:10.1007/s12325-020-01331-z · Cited by 45 · see citing works
Mechanisms Underlying Adenomyosis-Related Fibrogenesis
Kobayashi, H., Kishi, Y., & Matsubara, S. (2019) · Gynecologic and Obstetric Investigation · doi:10.1159/000502822 · Cited by 44 · see citing works
Classifying Adenomyosis: Progress and Challenges
Habiba, M. A., & Benagiano, G. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182312386 · Cited by 42 · see citing works
Path to diagnosis and women’s perspectives on the impact of endometriosis pain
Lamvu, G., Flores, O. A., Orady, M. E., & Schneider, B. (2020) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.1177/2284026520903214 · Cited by 42 · see citing works
Metabolic risk factors and fertility disorders: A narrative review of the female perspective
Westerman, R., & Kuhnt, A. (2021) · Reproductive Biomedicine & Society Online · doi:10.1016/j.rbms.2021.09.002 · Cited by 41 · see citing works
Saavalainen, L., Tikka, T., But, A., Gissler, M., Haukka, J. K., Tiitinen, A. E., Härkki, P., & Heikinheimo, O. (2017) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13244 · Cited by 38 · see citing works
A peek into the drug development scenario of endometriosis – A systematic review
Goenka, L., George, M., & Sen, M. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.03.092 · Cited by 37 · see citing works
Variables Associated with Endometriosis-related Pain: A Pilot Study using a Visual Analogue Scale
Cozzolino, M., Coccia, M. E., Lazzeri, G., Basile, F., & Troiano, G. (2019) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0039-1679879 · Cited by 35 · see citing works
The impact of adenomyosis on IVF outcomes: a prospective cohort study
Higgins, C., Fernandes, H., Costa, F. D. S., Martins, W. P., Vollenhoven, B. J., & Healey, M. (2021) · Human Reproduction Open · doi:10.1093/hropen/hoab015 · Cited by 35 · see citing works
Jaramillo‐Cardoso, A., Shenoy‐Bhangle, A. S., Garces-Descovich, A., Glickman, J. N., King, L. P., & Mortelé, K. J. (2019) · Abdominal Radiology · doi:10.1007/s00261-019-02199-6 · Cited by 34 · see citing works
Agostinis, C., Zorzet, S., Balduit, A., Zito, G., Mangogna, A., Macor, P., Romano, F., Toffoli, M., Belmonte, B., Morello, G., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.693118 · Cited by 32 · see citing works
Self-citationDevelopmental origins of endometriosis: a Swedish cohort study
Gao, M., Allebeck, P., Mishra, G. D., & Koupil, I. (2019) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2018-211811 · Cited by 31 · see citing works
Illum, L. R. H., Forman, A., Melgaard, A., Hansen, K. E., Hansen, S. N., Nyegaard, M., Hummelshøj, L., & Rytter, D. (2022) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.14364 · Cited by 31 · see citing works
Spontaneous hemoperitoneum in pregnancy: Italian prospective population‐based cohort study
Mazzocco, M., Donati, S., Maraschini, A., Corsi, E., Colciago, E., Guelfi, F., & Cetin, I. (2022) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1111/aogs.14431 · Cited by 26 · see citing works
Imaging of gastrointestinal endometriosis: what the radiologist should know
Jaramillo‐Cardoso, A., Shenoy‐Bhangle, A. S., VanBuren, W. M., Schiappacasse, G., Menias, C. O., & Mortelé, K. J. (2020) · Abdominal Radiology · doi:10.1007/s00261-020-02459-w · Cited by 28 · see citing works
Muhaidat, N., Saleh, S., Fram, K. M., Nabhan, M., Almahallawi, N., AlRyalat, S. A., Elfalah, M., & Elfalah, M. (2021) · BMC Women s Health · doi:10.1186/s12905-021-01530-y · Cited by 28 · see citing works
Borelli, V., Martinelli, M., Luppi, S., Vita, F., Romano, F., Fanfani, F., Trevisan, E., Celsi, F., Zabucchi, G., Zanconati, F., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2019.01543 · Cited by 28 · see citing works
Self-citationMedina‐Perucha, L., Pistillo, A., Raventós, B., Jacques‐Aviñó, C., Munrós-Feliu, J., Bueno, C. M., Valls-Llobet, C., Carmona, F., López‐Jiménez, T., Pujolar-Díaz, G., et al. (2022) · Women s Health · doi:10.1177/17455057221130566 · Cited by 27 · see citing works
Rowlands, I. J., Hockey, R., Abbott, J. A., Montgomery, G. W., & Mishra, G. D. (2022) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2022.04.002 · Cited by 26 · see citing works
Kim, H.-K., Lee, M., Hwang, H., Chung, Y., Cho, H., Yoon, H., Kim, M., Chae, K., Jung, C. Y., Kim, S., et al. (2020) · Journal of Epidemiology · doi:10.2188/jea.je20200002 · Cited by 25 · see citing works
Cegolon, L., Campbell, O. M. R., Alberico, S., Montico, M., Mastrangelo, G., Monasta, L., Ronfani, L., & Barbone, F. (2019) · PLoS ONE · doi:10.1371/journal.pone.0204919 · Cited by 24 · see citing works
Self-citationRisk factors for recurrence of deep infiltrating endometriosis after surgical treatment
Yela, D. A., Vitale, S. G., Vizotto, M. P., & Benetti‐Pinto, C. L. (2021) · Journal of Obstetrics and Gynaecology Research · doi:10.1111/jog.14837 · Cited by 23 · see citing works
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Juárez‐Barber, E., Francés‐Herrero, E., Corachán, A., Vidal, C., Gilés, J., Alamá, P., Faus, A., Pellicer, A., Cervelló, I., & Ferrero, H. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12020219 · Cited by 22 · see citing works
Güleken, Z., Bulut, H., Bulut, B., Paja, W., Parlińska‐Wojtan, M., & Depciuch, J. (2022) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2022.121119 · Cited by 22 · see citing works
Does endometriosis increase the risks of endometrial hyperplasia and endometrial cancer?
Kim, H., Kim, H. J., & Ahn, H. S. (2022) · Gynecologic Oncology · doi:10.1016/j.ygyno.2022.06.021 · Cited by 21 · see citing works
Kristjánsdóttir, Á., Rafnsson, V., & Geirsson, R. T. (2023) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.14556 · Cited by 20 · see citing works
Sebastián-León, P., Sanz, F. J., Molinaro, P., Pellicer, A., & Díaz-Gimeno, P. (2025) · Fertility and Sterility · doi:10.1016/j.fertnstert.2025.05.150 · Cited by 19 · see citing works
Increasing incidence and spatial hotspots of hospitalized endometriosis in France from 2011 to 2017
Moal, J. L., Goria, S., Chesneau, J., Fauconnier, A., Kvaskoff, M., de Crouy-Chanel, P., Kahn, V., Daraï, É., & Canis, M. J. (2022) · Scientific Reports · doi:10.1038/s41598-022-11017-x · Cited by 19 · see citing works
Associations of perinatal characteristics with endometriosis: a nationwide birth cohort study
Gao, M., Scott, K., & Koupil, I. (2019) · International Journal of Epidemiology · doi:10.1093/ije/dyz140 · Cited by 19 · see citing works
Increased incidence of ovarian cancer in both endometriosis and adenomyosis
Hermens, M., van Altena, A. M., Bulten, J., van Vliet, H. A. A. M., Siebers, A. G., & Bekkers, R. L. M. (2021) · Gynecologic Oncology · doi:10.1016/j.ygyno.2021.07.006 · Cited by 20 · see citing works
Epidemiology of Endometriosis in Spain and Its Autonomous Communities: A Large, Nationwide Study
Marfil, A. Á., Castillo, E. B., García, R. M., de Guevara, N. M. L., & Mazheika, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18157861 · Cited by 19 · see citing works
Malignant peritoneal mesothelioma in patients with endometriosis
Butnor, K. J., Rueckert, J., Pavlisko, E. N., Sporn, T. A., & Roggli, V. L. (2018) · Journal of Clinical Pathology · doi:10.1136/jclinpath-2018-205099 · Cited by 18 · see citing works
What abdominal radiologists should know about extragenital endometriosis-associated neuropathy
Filho, J. P. M., Leão, R. V., Horvat, N. D. S. M. R., Helito, P. V. P., Amaral, D. T., Viana, P. C. C., Louza, I. C. F., & Rodrigues, M. B. (2018) · Abdominal Radiology · doi:10.1007/s00261-018-1864-x · Cited by 16 · see citing works
Ekine, A. A., Fülöp, I., István, T., Árpád, R., Jeges, S., Koppán, Á., & Koppán, M. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020507 · Cited by 16 · see citing works
Pascolo, L., Pachetti, M., Camillo, A., Cernogoraz, A., Rizzardi, C., Vogel‐Mikuš, K., Zanconati, F., Salome-Pateyron, M., Suárez, V. T., Romano, F., et al. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.161028 · Cited by 16 · see citing works
Self-citationEstes, S. J., Soliman, A. M., Yang, H., Wang, J. J. J., & Freimark, J. (2020) · Advances in Therapy · doi:10.1007/s12325-020-01280-7 · Cited by 18 · see citing works
Yen, C., Hamdan, M., Hengrasmee, P., Huang, Z., Jeong, K., Dao, L. A., Lertvikool, S., Mogan, S., Pal, B., Sumapradja, K., et al. (2023) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.15142 · Cited by 16 · see citing works
Case Report of Cerebellar Endometriosis
Meggyesy, M. A., Friese, M., Gottschalk, J., & Kehler, U. (2020) · Journal of Neurological Surgery Part A Central European Neurosurgery · doi:10.1055/s-0040-1701622 · Cited by 15 · see citing works
Ricci, G., Castelpietra, E., Romano, F., Lorenzo, G. D., Zito, G., Ronfani, L., Biffi, S., & Monasta, L. (2020) · PLoS ONE · doi:10.1371/journal.pone.0230828 · Cited by 15 · see citing works
Self-citationRetractedMast Cell Tryptase and Carboxypeptidase A3 in the Formation of Ovarian Endometrioid Cysts
Atiakshin, D., Игоревна, П. О., Kostin, A. A., Mikhalyova, L., Buchwalow, I., & Tiemann, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076498 · Cited by 14 · see citing works
Warzecha, D., Pietrzak, B., Szymusik, I., Smiech, Z., & Wielgoś, M. (2020) · Ginekologia Polska · doi:10.5603/gp.a2020.0084 · Cited by 14 · see citing works
Maiorana, A., Alfano, P., Mercurio, A., Marcantonio, S., Minneci, G., Incandela, D., & Audino, P. (2023) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-023-06942-9 · Cited by 14 · see citing works
Endometriosis as a highly relevant yet neglected gynecologic condition in Asian women
Velarde, M. C., Bucu, M. E. M., & Habana, M. A. E. (2023) · Endocrine Connections · doi:10.1530/ec-23-0169 · Cited by 14 · see citing works
Endometriose Aspectos clínicos do diagnóstico ao tratamento
Silva, J. C. R. E., Valério, F. P., Herren, H., Troncon, J. K., Garcia, R. B., & Poli‐Neto, O. B. (2021) · Femina · doi:10.61622/0100-7254493202101 · Cited by 14 · see citing works
A Psychological Point of View on Endometriosis and Quality of Life: A Narrative Review
Farenga, E., Bulfon, M., Zonca, C. D., Tersar, C., Ricci, G., Lorenzo, G. D., & Clarici, A. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14050466 · Cited by 12 · see citing works
Self-citationGlobal and regional trends in the burden of surgically confirmed endometriosis from 1990 to 2021
Li, R., Zhang, L., & Liu, Y. (2025) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-025-01421-z · Cited by 12 · see citing works
Sun, Y., Leong, P., Huang, J., & Wei, J. C. (2022) · Scientific Reports · doi:10.1038/s41598-022-17343-4 · Cited by 11 · see citing works
Bourdon, M., Maignien, C., Giraudet, G., Estrade, J.-P., Indersie, É., Solignac, C., Arbo, E., Roman, H., Chapron, C., & Santulli, P. (2023) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2023.102708 · Cited by 11 · see citing works
Sinai, D., Avni, C., & Toren, P. (2024) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2024.111809 · Cited by 11 · see citing works
Localization of claudin-2 and claudin-3 in eutopic and ectopic endometrium is highly similar
Hoerscher, A., Horné, F., Dietze, R., Berkes, E., Oehmke, F., Tinneberg, H., Meinhold-Heerlein, I. M., & Konrad, L. (2020) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-020-05472-y · Cited by 11 · see citing works
The prevalence of endometrioma and associated malignant transformation in women over 40 years of age
Oral, E., Sözen, I., Uludağ, S., Demirkıran, F., İlvan, Ş., Öncül, M., & Çelik, H. G. (2020) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2020.101725 · Cited by 11 · see citing works
Siddiqui, S. E., & Bari, V. (2021) · Cureus · doi:10.7759/cureus.20650 · Cited by 11 · see citing works
Intestinal obstruction secondary to cecal endometriosis
Imasogie, D. E., Agbonrofo, P., Momoh, M., Obaseki, D., Obahiagbon, I., & Azeke, A. T. (2018) · Nigerian Journal of Clinical Practice · doi:10.4103/njcp.njcp_29_18 · Cited by 10 · see citing works
Adverse childhood experiences and the risk of endometriosis—a nationwide cohort study
Rostvall, M., Magnusson, C., Gemzell‐Danielsson, K., Kosidou, K., & Sieurin, J. (2025) · Human Reproduction · doi:10.1093/humrep/deaf101 · Cited by 9 · see citing works
Loughlin, A. M., Chiuve, S. E., Reznor, G., Doherty, M., Missmer, S. A., Chomistek, A. K., & Enger, C. L. (2021) · Pharmacoepidemiology and Drug Safety · doi:10.1002/pds.5333 · Cited by 9 · see citing works
Global Epidemiological Data on Endometriosis
Rowlands, I. J., Mishra, G. D., & Abbott, J. A. (2022) · Springer eBooks · doi:10.1007/978-3-030-97236-3_2 · Cited by 10 · see citing works
Dai, Y., Zhang, X., Xue, M., Zhou, Y., Sun, P.-R., & Leng, J. (2019) · Reproductive Sciences · doi:10.1177/1933719118820469 · Cited by 9 · see citing works
Dienogest and the Risk of Reoperation in Endometriosis
Seo, Y. S., Yuk, J., Cho, Y.-K., & Shin, J.-Y. (2021) · Journal of Personalized Medicine · doi:10.3390/jpm11090924 · Cited by 8 · see citing works
Investigating racial disparities in drug prescriptions for patients with endometriosis
Kashyap, A., Aziz, M., Sun, T., Gorman, S. L., Opoku‐Anane, J., & Elhadad, N. (2025) · npj Women s Health · doi:10.1038/s44294-025-00053-3 · Cited by 7 · see citing works
Recurrent embolic stroke associated with adenomyosis: A single case report and literature review
Morishima, Y., Ueno, Y., Satake, A., Fukao, T., Tsuchiya, M., Hata, T., Ogawa, T., Oishi, N., Nakajima, S., Hirata, S., et al. (2023) · Neurological Sciences · doi:10.1007/s10072-023-06701-3 · Cited by 7 · see citing works
Gynaecological pathologies leading to emergency department admissions: A cross-sectional study
Xholli, A., Londero, A. P., Mattos, L. C., Vujosevic, S., & Cagnacci, A. (2023) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2023.01.006 · Cited by 7 · see citing works
Adenomyosis in Pregnancy—Should It Be Managed in High-Risk Obstetric Units?
Orozco, R., Jiménez, J. C. V., Garcia, I. B., Lozano, M., Hernández, G., Pérez-Rey, D., Meloni, L., & Alcázar, J. L. (2023) · Diagnostics · doi:10.3390/diagnostics13061184 · Cited by 7 · see citing works
Catelan, D., Giangreco, M., Biggeri, A., Barbone, F., Monasta, L., Ricci, G., Romano, F., Rosolen, V., Zito, G., & Ronfani, L. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18137175 · Cited by 7 · see citing works
Self-citationEndometriosis: A Malignant Fingerprint
DeAngelo, C., Tarasiewicz, M. E. B., Strother, A. M., Taggart, H., Gray, C. J., Shanahan, M., Glowacki, C., Khandalavala, J., Talaska, E., Kinnan, A., et al. (2020) · Journal of Cancer Research and Therapeutic Oncology · doi:10.17303/jcrto.2020.8.206 · Cited by 6 · see citing works
Hagras, A. E., Hussein, N. A., Abdelazim, I. A., & Elhamamy, N. M. (2022) · Menopause Review/Przegląd Menopauzalny · doi:10.5114/pm.2022.124013 · Cited by 6 · see citing works
Clinical Manifestations of Adenomyosis Patients with or without Coexisting Endometriosis
Li, Y.-W., Liu, Y., Wang, S., Shi, H., Fan, Q., Zhu, L., Leng, J., Sun, D.-W., Sun, J. H., & Lang, J. (2018) · Chinese Medical Journal · doi:10.4103/0366-6999.243572 · Cited by 6 · see citing works
Microbial dysbiosis and disease pathogenesis of endometriosis, could there be a link?
Puca, J., & Hoyne, G. F. (2017) · doi:10.35841/medical-research.1.1.1-9 · Cited by 5 · see citing works
Jorgensen, E. M., Fitzgerald, A. C., & Clark, N. V. (2023) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0000000000000884 · Cited by 5 · see citing works
Endometrial Cancer with and without Endometriosis: Clinicopathological Differences
Minamikawa, T., Yachida, N., Takahashi, K., Saito, K., Sekizuka, T., Akashi, H., Suzuki, M. M., Mori, Y., Yamawaki, K., Suda, K., et al. (2023) · Cancers · doi:10.3390/cancers15235635 · Cited by 5 · see citing works
Gioia, F., Parola, A., & Boursier, V. (2023) · PubMed Central · doi:10.36131/cnfioritieditore20230506 · Cited by 5 · see citing works
Bolze, P., Descargues, P., Poilblanc, M., Cotte, E., Sesques, A., Paparel, P., Charlot, M., Hajri, T., Rousset, P., & Golfier, F. (2018) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2018.11.014 · Cited by 5 · see citing works
- Authors
- Morassutto, C., Monasta, L., Ricci, G., Barbone, F., & Ronfani, L.
- Affiliations
- IRCCS Materno Infantile Burlo Garofolo (IT)
- University of Trieste (IT)
- University of Udine (IT)
- Corresponding author
- Monasta, Lorenzo
- Venue
- PLOS ONE
- Publisher
- Public Library of Science (PLoS)
- Published
- 2016-04-21
- Volume
- 11
- Issue
- 4
- Pages
- e0154227
- ISSN
- 1932-6203 (ISSN-L)
- PMC
- PMC4839734
- OpenAlex
- W2341654050
- Cited by
- 157
- References
- 29
- Citations by year
- 2026: 7 · 2025: 13 · 2024: 12 · 2023: 20 · 2022: 24 · 2021: 19 · 2020: 31 · 2019: 14 · 2018: 8 · 2017: 5 · 2016: 3
- FWCI
- 13.29
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- PLoS ONE (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- ArTS Archivio della ricerca di Trieste (University of Trieste https://www.units.it/) (submittedVersion, cc-by)
- Institutional Research Information System (Università degli Studi di Trento) (submittedVersion, cc-by)
- Institutional Research Information System (University of Udine) (submittedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Regional Health Authority of Friuli Venezia Giulia (Dec. 979/Pren. 16/10/2014)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
- Keywords
- endometriosis, adenomyosis, incidence, prevalence, data linkage, hospital discharge data, hysterectomy, delayed diagnosis, women's health, Friuli Venezia Giulia
- MeSH terms
- Adolescent, Adult, Age Factors, Aged, Endometriosis, Female, Humans, Italy, Middle Aged, Registries, Incidence, Prevalence, Information Storage and Retrieval, Young Adult, Adenomyosis
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