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Cited by 15Gut microbiota and healthRabbits: Nutrition, Reproduction, HealthRuminant Nutrition and Digestive Physiology

Investigation into host selection of the cecal acetogen population in rabbits after weaning.

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Yang, Chunlei, Mi, Lan, Hu, Xialu, Liu, Jianxin, Wang, Jiakun·2016·PLOS ONE
DOI 10.1371/journal.pone.0158768PMC PMC4933399
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Abstract

Homoacetogenic bacteria have received attention as a hydrogenotrophic population that offers a significant energetic advantage to the host animal. Reductive acetogenesis is likely an important hydrogen disposal mechanism in the cecum of rabbits. However, molecular ecology information about cecal acetogen candidates has rarely been reported. To better understand the effect of host selection in the rabbit cecal acetogen community with respect to growth, rabbits at four different age stages (30, 60, 120 and 180 days) with the same diet were studied. Although the abundance of potential acetogens and methanogens was high in the cecum of rabbits undergoing growth, many novel potential acetogen populations were observed in the cecum of rabbits across all age groups. Young and adult rabbits had their own distinct acetogen community although they received the same diet, which suggests that as the rabbit ages, acetogens in the cecum undergo developmental changes because of host selection that are independent of diet, and perhaps the different acetogen communities result in different hydrogenotrophic characteristics. The within-group similarity increased with age, indicating that the acetogen community converges to a more homogeneous and stable arrangement with aging.

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  • Species of Blautia including B. coccoides, B. hydrogenotrophica, and B. schinikii, known acetogens, were found at high predominance in rabbit cecum.

    “In a recent study, species of Blautia including B. coccoides, B. hydrogenotrophica, and B. schinikii, which are known acetogens, were found at high predominance in rabbit cecum (Yang et al., 2016).”

    From Comparative Analysis of the Microbiota Between Sheep Rumen and Rabbit Cecum Provides New Insight Into Their Differential Methane Production (2018) · cites this paper as Yang et al., 2016

    The General Discussion says that a dominant rabbit-cecal acetogen was affiliated with Blautia and identifies B. coccoides, B. hydrogenotrophica, and B. schinkii as known acetogens. It does not say those three species themselves were found at high predominance; the phylogenetic analysis says most detected OTUs could not be classified to species or genus. The citing sentence also spells B. schinkii as “B. schinikii.” (LLM, conf=0.88)

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  • A strong positive correlation was found between A:P ratio and some bacterial taxa, including some taxa of Clostridiales, Lachnospiraceae, Ruminococcaceae, and Blautia, all of which contain known acetogens.

    “A strong positive correlation was also found between A: P ratio and some bacterial taxa, including some taxa of Clostridiales, Lachnospiraceae, Ruminococcaceae, and Blautia, all of which contain known acetogens (Yang et al., 2016).”

    From Comparative Analysis of the Microbiota Between Sheep Rumen and Rabbit Cecum Provides New Insight Into Their Differential Methane Production (2018) · cites this paper as Yang et al., 2016

    The Results and Discussion sections on cecal environment and acetogen phylogeny report the A:P ratio and identify potential acetogen sequences affiliated with Lachnospiraceae, Ruminococcaceae, Blautia, and Clostridiaceae (page numbers unavailable). They do not report a strong positive correlation between the ratio and those taxa; the paper instead analyzes the ratio and taxa separately. (LLM, conf=0.88)

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Sorted by citations

Authors
Yang, C., Mi, L., Hu, X., Liu, J., & Wang, J.
Affiliations
Zhejiang University (CN)
Corresponding author
Wang, Jiakun
ORCID
Venue
PLOS ONE
Publisher
Public Library of Science (PLoS)
Published
2016-07-05
Volume
11
Issue
7
Pages
e0158768
ISSN
1932-6203 (ISSN-L)
DOI
10.1371/journal.pone.0158768
PMC
PMC4933399
OpenAlex
W2466143257
Cited by
15
References
1
Citations by year
2023: 1 · 2022: 2 · 2020: 8 · 2019: 1 · 2018: 3
FWCI
0.69
Type
journal article
Language
en
Open access
Licence
Locations
  • PLoS ONE (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
the National Natural Science Foundation of China (31372337)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Rabbits: Nutrition, Reproduction, Health
  • Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Ruminant Nutrition and Digestive Physiology
Keywords
host selection, rabbits, hydrogenotrophic bacteria, reductive acetogenesis, gut microbiota, methanogenic archaea, weaning, microbial community stability
MeSH terms
Acetates, Age Factors, Animals, Bacteria, Cecum, Diet, Hydrogen, Male, Methane, Phylogeny, Population Dynamics, Rabbits, RNA, Ribosomal, 16S, Weaning, Sequence Analysis, DNA, Host-Pathogen Interactions, Microbiota

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