A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

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Items 101–200 of 345

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  3. The Two-Component Sensor Kinase TcsC and Its Role in Stress Resistance of the Human-Pathogenic Mold Aspergillus fumigatus
    Allison McCormick, Ilse Denise Jacobsen, Marzena Broniszewska, Julia Beck, Jürgen Heesemann, Frank Ebel · 2012 · PLoS ONE
  4. Culture-Independent Molecular Methods for Detection of Antifungal Resistance Mechanisms and Fungal Identification
    David S. Perlin, Nathan P. Wiederhold · 2017 · The Journal of Infectious Diseases
  5. The crucial role of iron uptake in Aspergillus fumigatus virulence
    Margo M. Moore · 2013 · Current Opinion in Microbiology
  6. Multiple mechanisms contribute to the development of clinically significant azole resistance in Aspergillus fumigatus
    Scott Moye-Rowley · 2015 · Frontiers in Microbiology
  7. Modulation of Host Angiogenesis as a Microbial Survival Strategy and Therapeutic Target
    Nir Osherov, Ronen Ben‐Ami · 2016 · PLoS Pathogens
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    Hsuan‐Chen Wang, Jui‐Chang Huang, Yong‐Hong Lin, Yu‐Hsin Chen, Ming‐I Hsieh, Pui‐Ching Choi, Hsiu‐Jung Lo, Wei‐Lun Liu, Ching‐Shan Hsu, Hsin‐I Shih et al. · 2017 · Environmental Microbiology
  9. A Cyp51B Mutation Contributes to Azole Resistance in Aspergillus fumigatus
    Irene González-Jiménez, Jose Lucio, Jorge Amich, Isabel Cuesta, Rafael Sánchez Arroyo, Laura Alcázar‐Fuoli, Emilia Mellado · 2020 · Journal of Fungi
  10. The C 2 H 2 Transcription Factor SltA Contributes to Azole Resistance by Coregulating the Expression of the Drug Target Erg11A and the Drug Efflux Pump Mdr1 in Aspergillus fumigatus
    Du, Wenlong, Zhai, Pengfei, Wang, Tingli, Bromley, Michael J., Zhang, Yuanwei, Lu, Ling · 2021 · Antimicrobial Agents and Chemotherapy
  11. Identification and Characterization of a Novel Aspergillus fumigatus Rhomboid Family Putative Protease, RbdA, Involved in Hypoxia Sensing and Virulence
    Vaknin, Yakir, Hillmann, Falk, Iannitti, Rossana, Ben Baruch, Netali, Sandovsky-Losica, Hana, Shadkchan, Yona, Romani, Luigina, Brakhage, Axel, Kniemeyer, Olaf, Osherov, Nir · 2016 · Infection and Immunity
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    Michael Bromley, Anna Johns, Emma Ann Davies, Marcin G. Fraczek, Jane Mabey Gilsenan, Natalya Kurbatova, Maria Keays, Misha Kapushesky, Marta Gut, Ivo Glynne Gut et al. · 2016 · PLoS ONE
  15. A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP
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  16. Determining Aspergillus fumigatus transcription factor expression and function during invasion of the mammalian lung
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  17. Recent trends in the epidemiology, diagnosis, treatment, and mechanisms of resistance in clinical Aspergillus species: A general review with a special focus on the Middle Eastern and North African region
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  18. Exploring the molecular mechanism of azole resistance in Aspergillus fumigatus
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  19. Identification of Hypoxia-Inducible Target Genes of Aspergillus fumigatus by Transcriptome Analysis Reveals Cellular Respiration as an Important Contributor to Hypoxic Survival
    Kristin L. Kroll, Vera Pähtz, Falk Hillmann, Yakir Vaknin, Wolfgang Schmidt‐Heck, Martin Roth, Ilse Denise Jacobsen, Nir Osherov, Axel A. Brakhage, Olaf Kniemeyer · 2014 · Eukaryotic Cell
  20. Two C4-sterol methyl oxidases (Erg25) catalyse ergosterol intermediate demethylation and impact environmental stress adaptation in Aspergillus fumigatus
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  21. Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach
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  22. Proteomic characterization of Aspergillus fumigatus isolated from air and surfaces of the International Space Station
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  23. Analysis of an Intrinsic Mycovirus Associated With Reduced Virulence of the Human Pathogenic Fungus Aspergillus fumigatus
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  24. Insights into the role of sterol metabolism in antifungal drug resistance: a mini-review
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  25. A Novel Sterol Regulatory Element-Binding Protein Gene (sreA) Identified in Penicillium digitatum Is Required for Prochloraz Resistance, Full Virulence and erg11 (cyp51) Regulation
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  26. Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast
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  27. Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
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  28. Antifungal activity of Myriocin on clinically relevant Aspergillus fumigatus strains producing biofilm
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  29. Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity
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  30. Sterol-Response Pathways Mediate Alkaline Survival in Diverse Fungi
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  31. Large-Scale Transcriptional Response to Hypoxia in Aspergillus fumigatus Observed Using RNAseq Identifies a Novel Hypoxia Regulated ncRNA
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  32. Subunit Architecture of the Golgi Dsc E3 Ligase Required for Sterol Regulatory Element-binding Protein (SREBP) Cleavage in Fission Yeast
    S. Julie‐Ann Lloyd, Sumana Raychaudhuri, Peter John Espenshade · 2013 · Journal of Biological Chemistry
  33. Genome mining and functional genomics for siderophore production in Aspergillus niger
    Angelique C. W. Franken, Beatrix Elisabeth Lechner, Ernst R. Werner, Hubertus Haas, B. Christien Lokman, Arthur F. J. Ram, Cees A. M. J. J. van den Hondel, Sandra de Weert, Peter J. Punt · 2014 · Briefings in Functional Genomics
  34. Composite Survival Index to Compare Virulence Changes in Azole-Resistant Aspergillus fumigatus Clinical Isolates
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  35. Implications of hypoxic microenvironments during invasive aspergillosis
    Sara J. Wezensky, Robert A. Cramer · 2010 · Medical Mycology
  36. Azole Drug Import into the Pathogenic Fungus Aspergillus fumigatus
    Brooke D. Esquivel, Adam R. Smith, Martin Zavřel, Theodore C. White · 2015 · Antimicrobial Agents and Chemotherapy
  37. Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast.
    Porter, Joshua R., Burg, John S., Espenshade, Peter J., Iglesias, Pablo A. · 2010 · Journal of Biological Chemistry
  38. Divergent Targets of Aspergillus fumigatus AcuK and AcuM Transcription Factors during Growth In Vitro versus Invasive Disease
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  39. Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus
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  40. Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum
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  41. Updates in Paracoccidioides Biology and Genetic Advances in Fungus Manipulation
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  42. Species Distribution and Antifungal Susceptibilities of Aspergillus Section Fumigati Isolates in Clinical Samples from the United States
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  43. The fungal UPR: A regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus
    Krishnan, Karthik, Askew, David S · 2014 · Virulence
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  45. Transcriptome analysis of cyclic AMP ‐dependent protein kinase A –regulated genes reveals the production of the novel natural compound fumipyrrole by A spergillus fumigatus
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  46. MDA5 Is an Essential Sensor of a Pathogen-Associated Molecular Pattern Associated with Vitality That Is Necessary for Host Resistance against Aspergillus fumigatus
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  47. The signal peptide peptidase SppA is involved in sterol regulatory element‐binding protein cleavage and hypoxia adaptation in Aspergillus nidulans
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  48. A Genome-wide Screen for Neurospora crassa Transcription Factors Regulating Glycogen Metabolism
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