The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda
Open accessAbstract
Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case. In November 2007, HF cases were reported in Bundibugyo District, Western Uganda. Laboratory investigation of the initial 29 suspect-case blood specimens by classic methods (antigen capture, IgM and IgG ELISA) and a recently developed random-primed pyrosequencing approach quickly identified this to be an Ebola HF outbreak associated with a newly discovered ebolavirus species (Bundibugyo ebolavirus) distantly related to the Côte d'Ivoire ebolavirus found in western Africa. Due to the sequence divergence of this new virus relative to all previously recognized ebolaviruses, these findings have important implications for design of future diagnostic assays to monitor Ebola HF disease in humans and animals, and ongoing efforts to develop effective antivirals and vaccines.
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Cites
The origin and evolution of Ebola and Marburg viruses
Suzuki, Y., & Gojobori, T. (1997) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a025820 · Cited by 108
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WHO Ebola Response Team (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1411100 · Cited by 1,674
Wauquier, N., Becquart, P., Padilla, C., Baize, S., & Leroy, E. M. (2010) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0000837 · Cited by 377
Molecular Evolution of Viruses of the Family Filoviridae Based on 97 Whole-Genome Sequences
Carroll, S. A., Towner, J. S., Sealy, T. K., McMullan, L. K., Khristova, M. L., Burt, F. J., Swanepoel, R., Rollin, P. E., & Nichol, S. T. (2013) · Journal of Virology · doi:10.1128/jvi.03118-12 · Cited by 177
Self-citationAlbariño, C. G., Shoemaker, T., Khristova, M. L., Wamala, J. F., Muyembe, J. J., Balinandi, S., Tumusiime, A., Campbell, S., Cannon, D., Gibbons, A., et al. (2013) · Virology · doi:10.1016/j.virol.2013.04.014 · Cited by 144
Self-citationDiagnostic metagenomics: potential applications to bacterial, viral and parasitic infections
PALLEN, M. J. (2014) · Parasitology · doi:10.1017/s0031182014000134 · Cited by 126
Metadata
- Authors
- Towner, J. S., Sealy, T. K., Khristova, M. L., Albariño, C. G., Conlan, S., Reeder, S. A., Quan, P.-L., Lipkin, W. I., Downing, R., Tappero, J. W., Okware, S., Lutwama, J., Bakamutumaho, B., Kayiwa, J., Comer, J. A., Rollin, P. E., Ksiazek, T. G., & Nichol, S. T.
- Venue
- PLoS Pathogens
- Publisher
- Public Library of Science (PLoS)
- Published
- 2008-11-21
- Volume
- 4
- Issue
- 11
- Pages
- e1000212
- ISSN
- 1553-7366 (ISSN-L)
- 1553-7374
- OpenAlex
- W2145933466
- Cited by
- 599
- References
- 1
- FWCI
- 25.07
- Type
- journal article
- Language
- en
- Open access
- gold
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- The paper
- Towner, J. S., Sealy, T. K., Khristova, M. L., Albariño, C. G., Conlan, S., Reeder, S. A., Quan, P.-L., Lipkin, W. I., Downing, R., Tappero, J. W., Okware, S., Lutwama, J., Bakamutumaho, B., Kayiwa, J., Comer, J. A., Rollin, P. E., Ksiazek, T. G., & Nichol, S. T. (2008). Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda. PLoS Pathogens. https://doi.org/10.1371/journal.ppat.1000212
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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