Cited by 11Sympathectomy and Hyperhidrosis TreatmentsDermatology and Skin DiseasesCardiovascular Syncope and Autonomic Disorders

Disorders of flushing

Yale, Steven H., Vasudeva, Shikha, Mazza, Joseph J., Rolak, Loren, Arrowood, Jodi, Stichert, Sara, Stratman, Erik S.·2005·Comprehensive Therapy

Abstract

Disorders of flushing encompass a broad spectrum of diverse acquired and inherited conditions. Chemical mediators involved in the flushing response are incompletely understood. Flushing episodes rarely can be associated with significant morbidity and mortality. The goal of the physician is to separate benign from potentially life-threatening conditions. Accurate diagnosis requires a thorough history and physical examination emphasizing the age of the patient, temporal association of flushing with occupation, environmental, stress, food, or drug exposure, and the duration of the episode. In some cases, despite a thorough evaluation, the etiology for flushing remains unknown. Understanding the distinct mechanisms that lead to flushing helps provide a rational approach to treatment.

Integrity signals

Registry

Crossref · 10.1385/comp:31:1:059

Cites

130 of 130 references verified0 citation errors · 0 not checkable

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  • Most symptoms attributable to mast cell activation, such as isolated flushing, pruritus, headache, abdominal pain, or tachycardia, are not specific to mast cells but can be found in other clinical conditions and disorders.

    “This is because most symptoms attributable to MCA, such as isolated fl ushing, pruritus, headache, abdominal pain, or tachycardia, are not speci fi c to MCs but can be found in other clinical conditions and disorders as well. 112-118”

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Authors
Yale, S. H., Vasudeva, S., Mazza, J. J., Rolak, L., Arrowood, J., Stichert, S., & Stratman, E. S.
Affiliations
  • Marshfield Clinic Research Foundation (US)
  • St. Joseph's Hospital (US)
Corresponding author
Yale, Steven H.
Venue
Comprehensive Therapy
Published
2005
Volume
31
Issue
1
Pages
059-071
ISSN
0098-8243 (ISSN-L)
OpenAlex
W2030780654
Cited by
11
References
130
Citations by year
2026: 1 · 2024: 1 · 2022: 1 · 2021: 1 · 2018: 1 · 2016: 1 · 2014: 1
FWCI
0.40
Type
journal article
Language
en
Open access
closed
Locations
  • Comprehensive Therapy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Sympathectomy and Hyperhidrosis Treatments
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
Keywords
chemical mediators, differential diagnosis
MeSH terms
Alcohol Drinking, Autonomic Nervous System Diseases, Diagnosis, Differential, Flushing, Humans, Marine Toxins, Neoplasms, Rosacea, Syndrome, Occupational Exposure, Postmenopause, Drug-Related Side Effects and Adverse Reactions

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