The DOI matches its Crossref record; 111 of the 111 references it cites were found in a registry or an index.
Mitochondria in Ischemic Stroke: New Insight and Implications
Open accessAbstract
Stroke is the leading cause of death and adult disability worldwide. Mitochondrial dysfunction has been regarded as one of the hallmarks of ischemia/reperfusion (I/R) induced neuronal death. Maintaining the function of mitochondria is crucial in promoting neuron survival and neurological improvement. In this article, we review current progress regarding the roles of mitochondria in the pathological process of cerebral I/R injury. In particular, we emphasize on the most critical mechanisms responsible for mitochondrial quality control, as well as the recent findings on mitochondrial transfer in acute stroke. We highlight the potential of mitochondria as therapeutic targets for stroke treatment and provide valuable insights for clinical strategies.
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Cites
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BackgroundPINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
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Cited by
Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
Qin, C., Yang, S., Chu, Y.-H., Zhang, H., Pang, X.-W., Chen, L., Zhou, L.-Q., Chen, M., Tian, D.-S., & Wang, W. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01064-1 · Cited by 939
Lipid nanoparticle-mediated drug delivery to the brain
Khare, P., Edgecomb, S. X., Hamadani, C. M., Tanner, E. E. L., & S Manickam, D. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114861 · Cited by 187
Inter and Intracellular mitochondrial trafficking in health and disease
Shanmughapriya, S., Langford, D., & Natarajaseenivasan, K. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101128 · Cited by 171
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Wang, L., Liu, Y., Zhang, X., Ye, Y., Xiong, X., Zhang, S., Gu, L., Jian, Z., & Wang, H. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.864426 · Cited by 121
Metadata
- Authors
- Liu, F., Lu, J., Manaenko, A., Tang, J., & Hu, Q.
- Venue
- Aging and disease
- Publisher
- Aging and Disease
- Published
- 2018
- Volume
- 9
- Issue
- 5
- Pages
- 924
- ISSN
- 2152-5250 (ISSN-L)
- OpenAlex
- W2889127185
- Cited by
- 322
- References
- 111
- FWCI
- 8.55
- Type
- journal article
- Language
- en
- Open access
- gold
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- Liu, F., Lu, J., Manaenko, A., Tang, J., & Hu, Q. (2018). Mitochondria in Ischemic Stroke: New Insight and Implications. Aging and disease. https://doi.org/10.14336/ad.2017.1126
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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