The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Systemic Effects of Chronic Obstructive Pulmonary Disease
Abstract
Chronic obstructive pulmonary disease (COPD) affects various structural and functional domains in the lungs. It also has significant extrapulmonary effects, the so-called systemic effects of COPD. Weight loss, nutritional abnormalities, and skeletal muscle dysfunction are well-recognized systemic effects of COPD. Other less well-known but potentially important systemic effects include an increased risk of cardiovascular disease and several neurologic and skeletal defects. The mechanisms underlying these systemic effects are unclear, but they are probably interrelated and multifactorial, including inactivity, systemic inflammation, tissue hypoxia and oxidative stress among others. These systemic effects add to the respiratory morbidity produced by the underlying pulmonary disease and should be considered in the clinical assessment as well as the treatment of affected patients.
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Cites
Celli, B. R., Cote, C. G., Marin, J. M., Casanova, C., Montes de Oca, M., Mendez, R. A., Pinto Plata, V., & Cabral, H. J. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa021322 · Cited by 4,015
A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema
(2003) · New England Journal of Medicine · doi:10.1056/nejmoa030287 · Cited by 2,071
Systemic oxidative stress in asthma, COPD, and smokers
Rahman, I., Morrison, D., Donaldson, K., & MacNee, W. (1996) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.154.4.8887607 · Cited by 774
Horwich, T. B., Fonarow, G. C., Hamilton, M. A., MacLellan, W. R., & Borenstein, J. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)01854-5 · Cited by 712
Skeletal Muscle Apoptosis and Weight Loss in Chronic Obstructive Pulmonary Disease
Agustí, A. G. N., Sauleda, J., Miralles, C., Gomez, C., Togores, B., Sala, E., Batle, S., & Busquets, X. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2108013 · Cited by 343
Self-citation
Cited by
Vestbo, J., Hurd, S. S., Agustí, A. G., Jones, P. W., Vogelmeier, C., Anzueto, A., Barnes, P. J., Fabbri, L. M., Martinez, F. J., Nishimura, M., et al. (2013) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201204-0596pp · Cited by 15,983
Self-citationRabe, K. F., Hurd, S., Anzueto, A., Barnes, P. J., Buist, S. A., Calverley, P., Fukuchi, Y., Jenkins, C., Rodriguez-Roisin, R., van Weel, C., et al. (2007) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200703-456so · Cited by 4,925
Complex chronic comorbidities of COPD
Fabbri, L. M., Luppi, F., Beghé, B., & Rabe, K. F. (2008) · European Respiratory Journal · doi:10.1183/09031936.00114307 · Cited by 660
Vogiatzis, I., Stratakos, G., Simoes, D. C. M., Terzis, G., Georgiadou, O., Roussos, C., & Zakynthinos, S. (2007) · Thorax · doi:10.1136/thx.2006.069310 · Cited by 122
Factors Limiting Exercise Tolerance in Chronic Lung Diseases
Vogiatzis, I., & Zakynthinos, S. (2012) · Comprehensive Physiology · doi:10.1002/cphy.c110015 · Cited by 77
Metadata
- Authors
- Agustí, A. G. N.
- Venue
- Proceedings of the American Thoracic Society
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-11-01
- Volume
- 2
- Issue
- 4
- Pages
- 367-370
- ISSN
- 1546-3222 (ISSN-L)
- 1943-5665
- OpenAlex
- W2114423036
- Cited by
- 292
- References
- 5
- FWCI
- 14.80
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
