Adenoviruses as gene/vaccine delivery vectors: promises and pitfalls

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

Buchbinder, S. P., Mehrotra, D. V., Duerr, A., Fitzgerald, D. W., Mogg, R., Li, D., Gilbert, P. B., Lama, J. R., Marmor, M., del Rio, C., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)61591-3 · Cited by 1,713

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

Raper, S. E., Chirmule, N. B., Lee, F. S., Wivel, N. A., Bagg, A., Gao, G., Wilson, J. M., & Batshaw, M. L. (2003) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2003.08.016 · Cited by 1,531

Adenoviruses: update on structure and function

Russell, W. C. (2008) · Journal of General Virology · doi:10.1099/vir.0.003087-0 · Cited by 462

Novel Adenovirus-Based Vaccines Induce Broad and Sustained T Cell Responses to HCV in Man

Barnes, E. J., Folgori, A., Capone, S., Swadling, L., Aston, S., Kurioka, A., Meyer, J., Huddart, R., Smith, K., Townsend, R., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003155 · Cited by 404

International seroepidemiology of adenovirus serotypes 5, 26, 35, and 48 in pediatric and adult populations

Barouch, D. H., Kik, S. V., Weverling, G. J., Dilan, R., King, S. L., Maxfield, L. F., Clark, S., Ng’ang’a, D., Brandariz, K., Abbink, P., et al. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.05.025 · Cited by 305

Virus-mediated gene delivery for human gene therapy

Giacca, M., & Zacchigna, S. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.04.008 · Cited by 302

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

Parker, A. L., Waddington, S. N., Nicol, C. G., Shayakhmetov, D. M., Buckley, S. M. K., Denby, L., Kemball‐Cook, G., Ni, S., Lieber, A., McVey, J. H., et al. (2006) · Blood · doi:10.1182/blood-2006-04-008532 · Cited by 297

International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials

Mast, T. C., Kierstead, L. S., Gupta, S. B., Nikas, A. A., Kallas, E. G., Novitsky, V., Mbewe, B., Pitisuttithum, P., Schechter, M., Vardas, E., et al. (2009) · Vaccine · doi:10.1016/j.vaccine.2009.10.145 · Cited by 283

Adenovirus Receptors

Zhang, Y., & Bergelson, J. M. (2005) · Journal of Virology · doi:10.1128/jvi.79.19.12125-12131.2005 · Cited by 262

Trial watch

Vacchelli, E., Eggermont, A. M. M., Sautès‐Fridman, C., Galon, J., Zitvogel, L., Kroemer, G., & Galluzzi, L. (2013) · OncoImmunology · doi:10.4161/onci.24612 · Cited by 260

Gene Therapy Leaves a Vicious Cycle

Goswami, R., Subramanian, G., Silayeva, L., Newkirk, I., Doctor, D. M., Chawla, K., Chattopadhyay, S., Chandra, D., Chilukuri, N., & Betapudi, V. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.00297 · Cited by 366

Viral vector‐based gene therapies in the clinic

Zhao, Z., Anselmo, A. C., & Mitragotri, S. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10258 · Cited by 269

Oral vaccination of fish: Lessons from humans and veterinary species

Embregts, C. W. E., & Forlenza, M. (2016) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2016.03.024 · Cited by 178

Biomaterial-guided delivery of gene vectors for targeted articular cartilage repair

Cucchiarini, M., & Madry, H. (2018) · Nature Reviews Rheumatology · doi:10.1038/s41584-018-0125-2 · Cited by 133

Gene therapy and genome surgery in the retina

DiCarlo, J. E., Mahajan, V. B., & Tsang, S. H. (2018) · Journal of Clinical Investigation · doi:10.1172/jci120429 · Cited by 127

Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5–based Constructs

Alonso-Padilla, J., Papp, T., Kaján, G. L., Benkő, M., Havenga, M. J. E., Lemckert, A. A. C., Harrach, B., & Baker, A. H. (2015) · Molecular Therapy · doi:10.1038/mt.2015.194 · Cited by 105

Key Role of the Scavenger Receptor MARCO in Mediating Adenovirus Infection and Subsequent Innate Responses of Macrophages

Maler, M. D., Nielsen, P. J., Stichling, N., Cohen, I., Ruzsics, Z., Wood, C., Engelhard, P., Suomalainen, M., Győry, I., Huber, M., et al. (2017) · mBio · doi:10.1128/mbio.00670-17 · Cited by 77

microRNA inhibitors: Natural and artificial sequestration of microRNA

Tang, L., Chen, H., Hao, N.-B., Tang, B., Guo, H., Yong, X., Dong, H. F., & Yang, S. (2017) · Cancer Letters · doi:10.1016/j.canlet.2017.05.025 · Cited by 74

Atomic Structures of Minor Proteins VI and VII in Human Adenovirus

Dai, X., Wu, L., Sun, R., & Zhou, Z. H. (2017) · Journal of Virology · doi:10.1128/jvi.00850-17 · Cited by 70

M cell targeting engineered biomaterials for effective vaccination

Islam, M. A., Firdous, J., Badruddoza, A. Z. M., Reesor, E., Azad, M. A., Hasan, A., Lim, M., Cao, W., Guillemette, S. R., & Cho, C. S. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.10.041 · Cited by 64

Innovative Strategies for Combating Multidrug-Resistant Tuberculosis: Advances in Drug Delivery Systems and Treatment

Omoteso, O. A., Fadaka, A. O., Walker, R. B., & Khamanga, S. M. (2025) · Microorganisms · doi:10.3390/microorganisms13040722 · Cited by 65

Adenovirus vectors in hematopoietic stem cell genome editing

Li, C., & Lieber, A. (2019) · FEBS Letters · doi:10.1002/1873-3468.13668 · Cited by 53

Adenovirus entry: Stability, uncoating, and nuclear import

Greber, U. F., & Suomalainen, M. (2022) · Molecular Microbiology · doi:10.1111/mmi.14909 · Cited by 50

Tropism and transduction of oncolytic adenovirus 5 vectors in cancer therapy: Focus on fiber chimerism and mosaicism, hexon and pIX

Stepanenko, A. A., & Chekhonin, V. P. (2018) · Virus Research · doi:10.1016/j.virusres.2018.08.012 · Cited by 49

Poly‐Adenine‐Based Spherical Nucleic Acids for Efficient Live‐Cell MicroRNA Capture

Jiao, K., Yan, Q., Guo, L., Qu, Z., Cao, S., Chen, X., Li, Q., Zhu, Y. J., Li, J., Wang, L., et al. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202017039 · Cited by 47

Shock wave-induced permeabilization of mammalian cells

Lopez-Marin, L. M., Rivera, A. L., Fernández, F., & Loske, A. M. (2018) · Physics of Life Reviews · doi:10.1016/j.plrev.2018.03.001 · Cited by 49

Recent advances in carbon quantum dots for gene delivery: A comprehensive review

Othman, H. O., Anwer, E. T., Ali, D. S., Hassan, R. O., Mahmood, E. E., Ahmed, R. A., Muhammad, R. F., & Smaoui, S. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31236 · Cited by 49

Evaluation of excipients for enhanced thermal stabilization of a human type 5 adenoviral vector through spray drying

LeClair, D. A., Cranston, E. D., Xing, Z., & Thompson, M. R. (2016) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2016.04.067 · Cited by 46

Orthopaedic Gene Therapy

Evans, C. H., Ghivizzani, S. C., & Robbins, P. D. (2021) · JBJS Reviews · doi:10.2106/jbjs.rvw.20.00220 · Cited by 42

Middle East respiratory syndrome: obstacles and prospects for vaccine development

Papaneri, A. B., Johnson, R. F., Wada, J., Bollinger, L., Jahrling, P. B., & Kuhn, J. H. (2015) · Expert Review of Vaccines · doi:10.1586/14760584.2015.1036033 · Cited by 34

Progress on adenovirus-vectored universal influenza vaccines

Xiang, K., Guan, Y., Yan, Z., Shanshan, Y., Zhang, L., Li, H., & Maosheng, S. (2015) · Human Vaccines & Immunotherapeutics · doi:10.1080/21645515.2015.1016674 · Cited by 34

Effect of Shear Stresses on Adenovirus Activity and Aggregation during Atomization To Produce Thermally Stable Vaccines by Spray Drying

Morgan, B. A., Manser, M., Jeyanathan, M., Xing, Z., Cranston, E. D., & Thompson, M. R. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c00317 · Cited by 30

The Ocular Gene Delivery Landscape

Sahu, B., Chug, I., & Khanna, H. (2021) · Biomolecules · doi:10.3390/biom11081135 · Cited by 28

Biomaterial-Guided Gene Delivery for Musculoskeletal Tissue Repair

Madrigal, J. L., Stilhano, R. S., & Silva, E. A. (2017) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2016.0462 · Cited by 28

Cryo-EM structure of enteric adenovirus HAdV-F41 highlights structural variations among human adenoviruses

Pérez-Illana, M., Martínez, M., Condezo, G. N., Hernando‐Pérez, M., Mangroo, C., Brown, M., Marabini, R., & Martı́n, C. S. (2021) · Science Advances · doi:10.1126/sciadv.abd9421 · Cited by 28

Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

Venkatesan, J. K., Rey‐Rico, A., & Cucchiarini, M. (2019) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-019-00179-x · Cited by 28

Inclusion of the murine IgGκ signal peptide increases the cellular immunogenicity of a simian adenoviral vectored Plasmodium vivax multistage vaccine

Fonseca, J. A., McCaffery, J. N., Caceres, J., Kashentseva, E. A., Singh, B., Dmitriev, I. P., Curiel, D. T., & Moreno, A. (2018) · Vaccine · doi:10.1016/j.vaccine.2018.03.091 · Cited by 27

MUC1 and survivin combination tumor gene vaccine generates specific immune responses and anti-tumor effects in a murine melanoma model

Zhang, H., Liu, C., Zhang, F.-F., Geng, F., Qiu, X., Lu, Z.-Z., Xu, P., Xie, Y., Wu, H., Yu, B., et al. (2016) · Vaccine · doi:10.1016/j.vaccine.2016.04.045 · Cited by 27

Current Status of Poultry Recombinant Virus Vector Vaccine Development

Wang, H., Tian, J., Zhao, Y., Zhao, Y., Yang, H., & Zhang, G. (2024) · Vaccines · doi:10.3390/vaccines12060630 · Cited by 26

Overexpression of Notch ligand Delta-like-1 by dendritic cells enhances their immunoregulatory capacity and exerts antiallergic effects on Th2-mediated allergic asthma in mice

Lee, C., Lin, C.-L., Leu, S., & Lee, Y. (2017) · Clinical Immunology · doi:10.1016/j.clim.2017.10.005 · Cited by 25

Retrograde axonal transport property of adeno-associated virus and its possible application in future

Wang, J., & Zhang, L. (2021) · Microbes and Infection · doi:10.1016/j.micinf.2021.104829 · Cited by 25

Interleukin-12-expressing oncolytic virus: A promising strategy for cancer immunotherapy

Alkayyal, A. A., Mahmoud, A. B., & Auer, R. C. (2016) · Journal of Taibah University Medical Sciences · doi:10.1016/j.jtumed.2016.04.002 · Cited by 22

Evaluation of the Efficacy of a Recombinant Adenovirus Expressing the Spike Protein of Porcine Epidemic Diarrhea Virus in Pigs

Liu, X., Zhao, D., Zhou, P., Zhang, Y., & Wang, Y. (2019) · BioMed Research International · doi:10.1155/2019/8530273 · Cited by 22

Applications of Gene Editing and Nanotechnology in Stem Cell-Based Therapies for Human Diseases

Bolideei, M., Barzigar, R., Gahrouei, R. B., Mohebbi, E., Haider, K. H., Paul, S., Paul, M. K., & Mehran, M. J. (2025) · Stem Cell Reviews and Reports · doi:10.1007/s12015-025-10857-0 · Cited by 22

Biology of Adenovirus Cell Entry

Luisoni, S., & Greber, U. F. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800276-6.00002-4 · Cited by 22

A compendium of adenovirus genetic modifications for enhanced replication, oncolysis, and tumor immunosurveillance in cancer therapy

Stepanenko, A. A., & Chekhonin, V. P. (2018) · Gene · doi:10.1016/j.gene.2018.08.069 · Cited by 21

Oncolytic virus preclinical toxicology studies

Rasa, A., & Alberts, P. (2022) · Journal of Applied Toxicology · doi:10.1002/jat.4408 · Cited by 20

Enhancement of the protective efficacy of a ROP18 vaccine against chronic toxoplasmosis by nasal route

Rashid, I., Moiré, N., Héraut, B., Dimier‐Poisson, I., & Mévélec, M.-N. (2016) · Medical Microbiology and Immunology · doi:10.1007/s00430-016-0483-9 · Cited by 20

Aminoclay as a highly effective cationic vehicle for enhancing adenovirus-mediated gene transfer through nanobiohybrid complex formation

Kim, S.-Y., Lee, S.-J., Han, H., & Lim, S. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.11.045 · Cited by 20

Identification of a Critical and Conformational Neutralizing Epitope in Human Adenovirus Type 4 Hexon

Tian, X., Qiu, H., Zhou, Z., Wang, S., Fan, Y., Li, X., Chu, R., Li, H., Zhou, R., & Wang, H. (2017) · Journal of Virology · doi:10.1128/jvi.01643-17 · Cited by 18

Viral Vectors, Engineered Cells and the CRISPR Revolution

DiCarlo, J. E., Deeconda, A., & Tsang, S. H. (2017) · Advances in experimental medicine and biology · doi:10.1007/978-3-319-63904-8_1 · Cited by 19

Will Nanotechnology Bring New Hope for Stem Cell Therapy?

Farzamfar, S., Nazeri, N., Salehi, M., Valizadeh, Ř., Marashi, S. M., Kouzehkonan, G. S., & Ghanbari, H. (2018) · Cells Tissues Organs · doi:10.1159/000500517 · Cited by 18

Human Adenovirus Serotype 3 Vector Packaged by a Rare Serotype 14 Hexon

Su, X., Tian, X., Jiang, Z., Ma, Q., Liu, Q., Lu, X., & Zhou, R. (2016) · PLoS ONE · doi:10.1371/journal.pone.0156984 · Cited by 17

Implementation of at‐line capillary zone electrophoresis for fast and reliable determination of adenovirus concentrations in vaccine manufacturing

van Tricht, E., Geurink, L., Garre, F. G., Schenning, M., Backus, H. H. J., Germano, M., Somsen, G. W., & van de Griend, C. S. (2019) · Electrophoresis · doi:10.1002/elps.201900068 · Cited by 17

Enhanced growth suppression of TERT-positive tumor cells by oncolytic adenovirus armed with CCL20 and CD40L

Liu, G., Li, Z., Li, Q., Jin, Y., Zhu, Y., Wang, Y., Liu, M., Li, Y., & Li, Y. (2015) · International Immunopharmacology · doi:10.1016/j.intimp.2015.07.005 · Cited by 17

Nanotechnology in stem cell research and therapy

Bharti, S., Anant, P. S., & Kumar, A. (2022) · Journal of Nanoparticle Research · doi:10.1007/s11051-022-05654-6 · Cited by 18

Molecular signatures for vaccine development

Maertzdorf, J., Kaufmann, S. H. E., & Weiner, J. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.03.075 · Cited by 14

In vivo direct reprogramming of liver cells to insulin producing cells by virus-free overexpression of defined factors

Yang, X., Ren, L., Lü, Y., Deng, C.-Y., & Li, F. (2017) · Endocrine Journal · doi:10.1507/endocrj.ej16-0463 · Cited by 14

The construction and proliferative effects of a lentiviral vector capable of stably overexpressing SPINK1 gene in human pancreatic cancer AsPC-1 cell line

Zhang, J., Wang, D., Hu, N., Wang, Q., Yu, S., & Wang, J. (2015) · Tumor Biology · doi:10.1007/s13277-015-4405-z · Cited by 13

Microbubble-mediated delivery of human adenoviruses does not elicit innate and adaptive immunity response in an immunocompetent mouse model of prostate cancer

Carlo, F. D., Thomas, L., Brooke, B., Varney, E. T., Nande, R. P., Boskovic, O., Marshall, G. D., Claudio, P. P., & Howard, C. M. (2019) · Journal of Translational Medicine · doi:10.1186/s12967-019-1771-0 · Cited by 13

Silk fibroin scaffolds loaded with angiogenic genes in adenovirus vectors for tissue regeneration

Wang, W., Yu, Y., Jiang, Y., Qu, J., Niu, L., Yang, J., & Li, M. (2019) · Journal of Tissue Engineering and Regenerative Medicine · doi:10.1002/term.2819 · Cited by 13

Structure-based assessment of protein-protein interactions and accessibility of protein IX in adenoviruses with implications for antigen display

Matteson, N. L., Barry, M. A., & Reddy, V. S. (2018) · Virology · doi:10.1016/j.virol.2018.01.007 · Cited by 12

Molecular mechanisms of transcription factor mediated cell reprogramming: conversion of liver to pancreas

Wild, S. L., & Tosh, D. (2021) · Biochemical Society Transactions · doi:10.1042/bst20200219 · Cited by 11

Suppression of hepatitis B virus antigen production and replication by wild-type HBV dependently replicating HBV shRNA vectors in vitro and in vivo

Li, B., Sun, S., Li, M., Cheng, X., Li, H., Kang, F., Kang, J., Dörnbrack, K., Nassal, M., & Sun, D. (2016) · Antiviral Research · doi:10.1016/j.antiviral.2016.08.007 · Cited by 11

The State of the Art of Investigational and Approved Nanomedicine Products for Nucleic Acid Delivery

Paredes, K. O., Ruíz-Cabello, J., Alarcón, D. I., & Filice, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814470-1.00015-0 · Cited by 11

Interleukin-38-overexpressing adenovirus infection in dendritic cell-based treatment enhances immunotherapy for allergic asthma via inducing Foxp3+ regulatory T cells

Chuang, H., Chang, J., Fan, Y.-Y., Hsieh, C., & Lee, Y. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117738 · Cited by 9

Immunogenicity and protective efficacy of a recombinant adenoviral based vaccine expressing heat-stable enterotoxin (STa) and K99 adhesion antigen of enterotoxigenic Escherichia coli in mice

Deng, G., Li, W., Wu, X., Bao, S., Zeng, J., Zhao, N., Luo, M., Liu, X., & Wang, Y. (2015) · Molecular Immunology · doi:10.1016/j.molimm.2015.10.016 · Cited by 9

Direct reprogramming of hepatocytes into insulin-producing cells for anti-diabetic treatment by ultrasound-targeted microbubble destruction enhanced hydrodynamic gene delivery.

Yang, X., Wang, H., Lu, W.-L., Ma, W., Zhang, H., & Li, F. (2020) · PubMed Central · Cited by 8

Current advances in developing cationic lipid-based nanoparticles as a vehicle for improving adenoviral gene delivery

Kim, S., Lee, M.-K., & Lim, S. (2016) · Journal of Pharmaceutical Investigation · doi:10.1007/s40005-016-0261-0 · Cited by 8

Tracing goes viral: Viruses that introduce expression of fluorescent proteins in chemically-specific neurons

Luchicchi, A., Pattij, T., Viaña, J. N. M., de Kloet, S. F., & Marchant, N. J. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2020.109004 · Cited by 8

The Use of Viral Vectors for Gene Therapy and Vaccination in Tuberculosis

Mata‐Espinosa, D., Lara-Espinosa, J. V., Barrios‐Payán, J., & Hernández‐Pando, R. (2023) · Pharmaceuticals · doi:10.3390/ph16101475 · Cited by 8

Long Non-Coding RNAs in Cardiac Hypertrophy

Mangraviti, N., & Windt, L. J. D. (2022) · Frontiers in Molecular Medicine · doi:10.3389/fmmed.2022.836418 · Cited by 7

Fast, selective and quantitative protein profiling of adenovirus-vector based vaccines by ultra-performance liquid chromatography

van Tricht, E., de Raadt, P., Verwilligen, A., Schenning, M., Backus, H. H. J., Germano, M., Somsen, G. W., & van de Griend, C. S. (2018) · Journal of Chromatography A · doi:10.1016/j.chroma.2018.10.045 · Cited by 7

Bioengineering strategies for gene delivery

Shams, S., & Silva, E. A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816221-7.00004-5 · Cited by 8

Immunogenicity of Different Forms of Middle East Respiratory Syndrome S Glycoprotein

Ozharovskaia, T. A., Zubkova, O. V., Dolzhikova, I. V., Gromova, A. S., Grousova, D. M., Ильдарович, Т. А., Popova, O. D., Shcheblyakov, D. V., Scherbinin, D. N., Dzharullaeva, A. S., et al. (2019) · Acta Naturae · doi:10.32607/20758251-2019-11-1-38-47 · Cited by 6

Development and characterization of a vector system based on the simian adenovirus type 25

Ozharovskaia, T. A., Popova, O. D., Zubkova, O. V., Викторовна, В. И., Pochtovyy, A., Shcheblyakov, D. V., Gushchin, V. А., Logunov, D., & Al, G. (2023) · Bulletin of Russian State Medical University · doi:10.24075/brsmu.2023.006 · Cited by 6

Dose Effects of Recombinant Adenovirus Immunization in Rodents

Weaver, E. A. (2019) · Vaccines · doi:10.3390/vaccines7040144 · Cited by 6

Vaccines And Advanced Vaccines: -A landscape for advanced vaccine technology against infectious disease ,COVID-19 and tumorPreprint

Cai, X., Zhang, X., & Bai, H. (2020) · OSF Preprints (OSF Preprints) · doi:10.31219/osf.io/ypgx4 · Cited by 6

Semi-quantification of antibody-dependent enhancement (ADE) in the uptake of Adenovirus serotype 5 into THP-1 cells

Valliyott, L., Dungdung, R., & Pilankatta, R. (2019) · Analytical Biochemistry · doi:10.1016/j.ab.2019.113568 · Cited by 5

Activation of OX40 and CD27 Costimulatory Signalling in Sheep through Recombinant Ovine Ligands

Rojas, J. M., Alejo, A., Avia, M., Rodríguez-Martín, D., Sánchez, C., Alcamı́, A., Sevilla, N., & Martı́n, V. (2020) · Vaccines · doi:10.3390/vaccines8020333 · Cited by 5

A Partial E3 Deletion in Replication-Defective Adenoviral Vectors Allows for Stable Expression of Potentially Toxic Transgene Products

Haut, L. H., Gill, A. L., Kurupati, R. K., Bian, A., Li, Y., Giles‐Davis, W., Xiang, Z., Zhou, X., & Ertl, H. C. J. (2016) · Human Gene Therapy Methods · doi:10.1089/hgtb.2016.044 · Cited by 5

rAAV9-UPII-TK-EGFP can precisely transduce a suicide gene and inhibit the growth of bladder tumors

Lian, F., Ye, Q., Feng, B. C., Cheng, H., Niu, S., Fan, N., Wang, D., & Wang, Z. (2020) · Cancer Biology & Therapy · doi:10.1080/15384047.2020.1844115 · Cited by 4

Scavenger Receptors in the Pathogenesis of Viral Infections

Fierro, N. A., Rivera-Toledo, E., Ávila-Horta, F., Anaya-Covarrubias, J. Y., & Mendlovic, F. (2022) · Viral Immunology · doi:10.1089/vim.2021.0167 · Cited by 6

Razrabotka i harakteristika vektornoj sistemy na osnove adenovirusa obez'yan 25-go serotipa

Ozharovskaia, T. A., Попова, О., Zubkova, O. V., Викторовна, В. И., Pochtovyy, A. A., Щебляков, Д. В., Алексеевич, Г. В., Логунов, Д. Ю., & Al, G. (2023) · Вестник Российского государственного медицинского университета · doi:10.24075/vrgmu.2023.006 · Cited by 4

Fiber-modified adenovirus-mediated suicide gene therapy can efficiently eliminate bladder cancer cells in vitro and in vivo

Wang, D., Zhao, M., Liu, Y.-Q., Liu, X.-W., Niu, H., Song, Y., & Tian, Y. (2016) · Oncotarget · doi:10.18632/oncotarget.12324 · Cited by 4

Gene Therapy in Skin and Wound Healing

Nuutila, K., Singh, M., & Eriksson, E. K. (2018) · Springer eBooks · doi:10.1007/978-3-319-78957-6_2 · Cited by 4

Effect of Genetic Modifications on Physical and Functional Titers of Adenoviral Cancer Gene Therapy Constructs

Heiniö, C., Sorsa, S., Siurala, M., Grönberg-Vähä-Koskela, S. A. M., Havunen, R., Haavisto, E., Koski, A., Hemminki, O., Zafar, S., Cervera-Carrascón, V., et al. (2019) · Human Gene Therapy · doi:10.1089/hum.2018.240 · Cited by 4

Hitching a Ride: Enhancing Nucleic Acid Delivery into Target Cells Through Nanoparticles

Penumarthi, A., Basak, P., Smooker, P. M., & Shukla, R. (2020) · Environmental chemistry for a sustainable world · doi:10.1007/978-3-030-29207-2_11 · Cited by 4

Poly‐Adenine‐Based Spherical Nucleic Acids for Efficient Live‐Cell MicroRNA Capture

Jiao, K., Yan, Q., Guo, L., Qu, Z., Cao, S., Chen, X., Li, Q., Zhu, Y. J., Li, J., Wang, L., et al. (2021) · Angewandte Chemie · doi:10.1002/ange.202017039 · Cited by 3

A Critical Assessment of COVID-19 Genomic Vaccines

Sabbah, D. A., Hajjo, R., & Sunoqrot, S. (2023) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026623666230825094341 · Cited by 4

Replication-Competent Viral Vectors for Vaccine Delivery

Parks, C. L. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802302-0.00001-7 · Cited by 3

Comparison of Dendritic Cell Activation by Virus-Based Vaccine Delivery Vectors Emphasizes the Transcriptional Downregulation of the Oxidative Phosphorylation Pathway

Tsitoura, E., Kazazi, D., Arslan, D. Ö., Sever, E. A., Khalili, S., Vassilaki, N., Aslanoglou, E., Dérian, N., Six, A., Sezerman, O. U., et al. (2018) · Human Gene Therapy · doi:10.1089/hum.2018.161 · Cited by 2

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Turner, A. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803942-7.00014-3 · Cited by 2

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Kim, Y. C., & Reyes‐Sandoval, A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-90248-9.00003-6 · Cited by 2

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Ayalew, L. E., Gaba, A., Wang, W., & Tikoo, S. K. (2020) · Springer eBooks · doi:10.1007/978-3-030-51927-8_5 · Cited by 2

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Hidalgo, P., & González, R. A. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-818731-9.00066-5 · Cited by 2

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Liu, Y., Li, W., Li, G., Li, X., Cao, H., Wang, Y., & Zheng, S. J. (2026) · Microbial Pathogenesis · doi:10.1016/j.micpath.2026.108460 · Cited by 1

Diagnosis and Assessment of Microbial Infections with Host and Microbial microRNA Profiles

Cui, L., Stratton, C. W., & Tang, Y. (2012) · Springer eBooks · doi:10.1007/978-1-4614-3970-7_46 · Cited by 1

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Rey‐Rico, A., Carballo-Pedrares, N., Venkatesan, J. K., Madry, H., & Cucchiarini, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-823948-3.00034-8 · Cited by 1

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Ying-Fen, L., Chun, S., Jun, Y., Shuai-Bo, H., Chen, Y., Gui-lan, W., KaiGong, W., Shan, C., Er-Peng, Z., & Cheng, Z. (2025) · Poultry Science · doi:10.1016/j.psj.2025.105185 · Cited by 1

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Kuznetsova, N. A., Gushchin, V. А., Marchuk, E. V., Siniavin, A. E., Kleymenov, D. A., Nikiforova, M. A., Zubkova, O. V., Popova, O., Викторовна, В. И., Ozharovskaia, T. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.16.633390 · Cited by 1

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Lenman, A. (2016) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

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Nasz, I., & Ádám, É. (2001) · Acta Microbiologica et Immunologica Hungarica · doi:10.1556/amicr.48.2001.3-4.6 · Cited by 17

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Park, A., & Lee, J. Y. (2024) · The Journal of Microbiology · doi:10.1007/s12275-024-00159-4 · Cited by 28