The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair
Abstract
BACKGROUND: Mesenchymal stem cells (MSC) are multipotent cells with the ability to differentiate into mesenchyme-derived cells including osteoblasts and chondrocytes. OBJECTIVE: To provide an overview and expert opinion on the in vivo ability of MSC to home into tissues, their regenerative properties and potential applications for cell-based therapies to treat bone and cartilage disorders. METHODS: Data sources including the PubMed database, abstract booklets and conference proceedings were searched for publications pertinent to MSC and their properties with emphasis on the in vivo studies and clinical use in cartilage and bone regeneration and repair. The search included the most current information possible. CONCLUSION: MSC can migrate to injured tissues and some of their reparative properties are mediated by paracrine mechanisms including their immunomodulatory actions. MSC possess a critical potential in regenerative medicine for the treatment of skeletal diseases, such as osteoarthritis or fracture healing failure, where treatments are partially effective or palliative.
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Cites
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Human mesenchymal stem cells modulate allogeneic immune cell responses
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Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
Caplan, A. I. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21200 · Cited by 1,956
Human mesenchymal stem cells modulate B-cell functions
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A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)
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Tissue-engineered bone regeneration
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Imaging tri-fusion multimodality reporter gene expression in living subjects
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Cited by
Regenerative Effects of Transplanted Mesenchymal Stem Cells in Fracture Healing
Granero-Moltó, F., Weis, J. A., Miga, M. I., Landis, B., Myers, T. J., O'Rear, L., Longobardi, L., Jansen, E. D., Mortlock, D. P., & Spagnoli, A. (2009) · Stem Cells · doi:10.1002/stem.103 · Cited by 530
Self-citationDemoor, M., Ollitrault, D., Gomez-Leduc, T., Bouyoucef, M., Hervieu, M., Fabre, H., Lafont, J., Denoix, J.-M., Audigié, F., Mallein-Gerin, F., et al. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.02.030 · Cited by 296
Park, K.-S., Kim, Y.-S., Kim, J.-H., Choi, B., Kim, S.-H., Tan, A. H.-K., Lee, M.-S., Lee, M.-K., Kwon, C.-H., Joh, J.-W., et al. (2010) · Transplantation · doi:10.1097/tp.0b013e3181c7dc99 · Cited by 288
Stem cell homing in musculoskeletal injury
Fong, E. L. S., Chan, C. K., & Goodman, S. B. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2010.08.101 · Cited by 212
Akkouch, A., Zhang, Z., & Rouabhia, M. (2014) · Journal of Biomaterials Applications · doi:10.1177/0885328213486705 · Cited by 76
Metadata
- Authors
- Granero-Molto, F., Weis, J. A., Longobardi, L., & Spagnoli, A.
- Venue
- Expert Opinion on Biological Therapy
- Publisher
- Informa Healthcare
- Published
- 2008-02-25
- Volume
- 8
- Issue
- 3
- Pages
- 255-268
- ISSN
- 1471-2598 (ISSN-L)
- 1744-7682
- OpenAlex
- W2017741368
- Cited by
- 176
- References
- 9
- FWCI
- 7.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- Granero-Molto, F., Weis, J. A., Longobardi, L., & Spagnoli, A. (2008). Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair. Expert Opinion on Biological Therapy. https://doi.org/10.1517/14712598.8.3.255
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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