Direct nose to brain drug delivery via integrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting

Cited by (482)

Items 401–482 of 482

1. Construction of an Asian standardized nasal cavity model via image registration for computational analysis of drug particle deposition
   Ziyu Jin, Gang Guo, Shiqi Wang, Jingyu Shi, Zhenbo Tong, Langui Xie · 2026 · Journal of Aerosol Science
2. Unveiling the Novel Multitarget Antidepressant Mechanisms of Ligustilide in Postpartum Depression: An Integrative Network Pharmacology and Molecular Simulation Study
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3. Intranasal administration in modulating depressive-like behavior and reconstructing treatment paradigms through neuroinflammation and neurotrophic pathways
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4. Nanomedicines for neurodegenerative ageing: nasal delivery innovations for Alzheimer’s and Parkinson’s disease
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5. Nanostructured Lipid Carriers for Synergistic Nose-to-Brain Delivery of Ropinirole Hydrochloride with Anise Oil for Parkinson’s Disease: Formulation and Preclinical Assessment
   Mukesh Pandurang Ratnaparkhi, Prachi D. Jadhav, Aditya Kakad, Rahul H. Khiste, Sampada D. Dalvi · 2026 · BioNanoScience
6. Microneedle-mediated drug delivery systems for brain diseases
   Jia Li, Yubo Wang, Xin Ma, Xinming Bi, Tianjiao Wu, Ning Zhang, Fashan Wang, Tongfeng Liu, Fang Geng · 2026 · Nanomedicine Nanotechnology Biology and Medicine
7. Intranasal Pacritinib-loaded nanoemulsion for Glioblastoma management: In Vitro, ex Vivo, 3D spheroid and In vivo brain biodistribution studies
   Anupama Sikder, Shraddha Naresh Katarpawar, Vivek Phatale, Ganesh B. Vambhurkar, Suraj S. Wagh, Rahul Kumar, Giriraj Pandey, Amol G. Dikundwar, Saurabh Srivastava · 2026 · European Journal of Pharmaceutics and Biopharmaceutics
8. Morphological evaluation using MRI of the olfactory filaments (fila) in a post‐traumatic olfactory rat model
   Zhifu Sun, Xing Gao, Jayant Marian Pinto, He Yin, QingXian Yang, Jun Tian, Qianwen Lv, Yongxiang Wei · 2018 · World Journal of Otorhinolaryngology - Head and Neck Surgery
9. The Strategies of Nanomaterials for Drug Delivery and Release
   Jinjin Wang, Qianqian Huang, Xing‐Jie Liang · 2019 · Springer eBooks
10. Esketamina intranasal: un nuevo abordaje para el tratamiento de la depresión resistente al tratamiento
    Ana María González-Pinto · 2020 · Psiquiatría Biológica
11. Experimental models for evaluation of direct nose-to-brain drug delivery
    Vinit V. Agnihotri, Ashish Prakash Gorle, Chandrakantsing Vijaysing Pardeshi, Sanjay Javerilal Surana · 2021 · Elsevier eBooks
12. Supramolecular hydrogels as drug delivery systems for nerve regeneration and wound healing
    Pavani Sanapala, Sudhakar Pola · 2022 · Elsevier eBooks
13. An Overview on Nanocarriers for Nasal Delivery
    Sunita Dahiya, Rajiv Dahiya · 2023 · Springer eBooks
14. Formulation Strategies for Nose-to-Brain Drug Delivery
    Manisha Vohra, Mohammad Amir, Amit Sharma, Sheetu Wadhwa · 2022 · Journal of Pharmaceutical Technology Research and Management
15. Nanomaterial-based approach in stroke
    Bijoyani Ghosh, Aishika Datta, Deepaneeta Sarmah, Nikita Rana, Antra Chaudhary, Anupom Borah, Pallab Bhattacharya · 2024 · Elsevier eBooks
16. Cell-based in vitro models for nasal permeability studies
    Simone Ladel, Katharina Schindowski · 2024 · Elsevier eBooks
17. Nanocarriers: Delivery Routes
    Andrey Silva Morawski, José Adão Carvalho Nascimento Júnior, Mairim Russo Serafini, Luíza Abrahão Frank · 2024 · Springer eBooks
18. Liposomes for drug delivery to the brain
    Mukta Agrawal, Snigdha Singh, Amit Alexander · 2024 · Elsevier eBooks
19. Quality by design approach for development and characterization of gabapentin-loaded solid lipid nanoparticles for intranasal delivery: In vitro, ex vivo, and histopathological evaluation.
    Mahmut Ozan Toksoy, Fırat Aşir, Mert Can Güzel · 2024 · PubMed Central
20. Theranostic Application of Nanomedicine in Neurodegenerative Diseases: Current and Future Perspectives
    Garima, Khalid Imtiyaz, Pooja Pooja, Prachi Pannu, Anjali Sharma, Smriti Raina, Sugandh Kumar, Syed Tauqeer Anwer, M. Moshahid Alam Rizvi, Shailendra Kumar Sinha et al. · 2024 · Springer eBooks
21. Cannabis use, oral dysbiosis, and neurological disorders
    Amber A. Hazzard, Marice K. McCrorey, Tabinda Salman, Douglas E. Johnson, Zhenwu Luo, Xiaoyu Fu, Andrew P. Keegan, Andreana M. Benitez, Sylvia Fitting, Wei Jiang · 2024 · NeuroImmune Pharmacology and Therapeutics
22. Drugs Targeting Cerebrovascular and Neurological Diseases via Green Solid Lipid Nanoparticles
    Vishal Garg, Manish Gupta, Naveen Garg, Ajay Kumar Saini, Mr. Jitendra Saini · 2024 · International Journal of Recent Research and Review
23. A Methodical Review of Intranasal Delivery of Nanocarriers for the Treatment of Glioblastoma: An Emerging Therapeutic Option
    Pankaj Popli, Monika, Pragi, Varun Kumar, Deepanshu Sharma, Shrikant, Shabnam Kumari, Deepak Garg · 2024 · Current Drug Therapy
24. 4.30 Nanomaterials for Drug Delivery to the Brain
    A. Gaudin, Young-Eun Seo, E. Song, E. Quijano, Amanda R. King, W. Saltzman · 2017 · Elsevier eBooks
25. KATI LİPİT NANOPARTİKÜLLER VE BEYNE ÖZGÜ İLAÇ TAŞIYICI SİSTEM OLARAK UYGULAMALARI
    Mahmut Ozan Toksoy, Figen Tırnaksız · 2021 · Ankara Universitesi Eczacilik Fakultesi Dergisi
26. Nose-to-Brain Targeted Drug Delivery Bypassing the Blood-Brain Barrier
    Manju Pandey · 2022 · Advances in bioinformatics and biomedical engineering book series
27. BIODISTRIBUTION OF DOXORUBICIN-LOADED SUCCINOYL CHITOSAN NANOPARTICLES IN MICE INJECTED VIA INTRAVENOUS OR INTRANASAL ROUTES
    Anastasia A. Zubareva, Tatyana Shcherbinina, В. П. Варламов, E. V. Svirshchevskaya · 2014 · Progress on Chemistry and application of Chitin and its Derivatives
28. Nanomaterials in nose-to-brain delivery
    Harsha Jain, Harshita Dalvi, Aditi Bhat, Aashruti Agrawal, Jitender Madan, Pankaj Kumar Singh, Neelesh Kumar Mehra, Shashi Bala Singh, Saurabh Srivastava · 2022 · Elsevier eBooks
29. Two-Part Reactive Formulations for Intranasal Delivery of Benzodiazepines
    Davin Rautiola · 2019 · University of Minnesota Digital Conservancy (University of Minnesota)
30. Expert Opinion
    Eliana B. Souto · 2013 · Expert Opinion on Drug Delivery
31. Statistical Shape Modelling and Segmentation of the Respiratory Airway
    Robin Huang · 2016 · The Sydney eScholarship Repository (The University of Sydney)
32. Mitochondria-Targeted Nanoparticles
    Magisetty Obulesu · 2019 · Elsevier eBooks
33. Nasal delivery nanoparticles
    Magisetty Obulesu · 2020 · Elsevier eBooks
34. MEDICAL OR THERAPEUTICAL APPLICATIONS OF OIL‐IN‐WATER NANOSIZED EMULSIONS
    Oly Katari, T. Shunmugaperumal · 2020
35. Formulation development and characterization of Chitosan nanoparticles bearing Rizatriptan Benzoate for intranasal delivery
    Jalaram H. Thakkar, Shailesh T. Prajapati · 2020 · Journal of Emerging Technologies and Innovative Research
36. Nanomedicines for CNS therapy: Fundamental aspects
    Drashti Desai, Bala R. Prabhakar, Pravin K. Shende · 2021 · Elsevier eBooks
37. Potential of naso-brain drug delivery in glioblastoma therapy
    Amarjitsing Rajput, Nikunj Tandel, Swapnil Borse, Shital Butani · 2021 · Elsevier eBooks
38. Applications of nose-to-brain delivery in nanodiagnosis and nanotherapy of neurodegenerative disorders
    Abhijeet Dattatraya Kulkarni, Mahesh N. Shinde, Gaurav Ambadas Sonawane, Hitesh Raotole, Rohit Pande, Chandrakantsing Vijaysing Pardeshi · 2021 · Elsevier eBooks
39. The Past, Present, and Future of Drug Development and Treatment in Sleep Disorders
    A. Guglietta · 2015 · Milestones in drug therapy
40. The Role of Biomedical Nanotechnology in CNS and Neurological Disorders
    Madhuri Sharon · 2022
41. Biological Evaluation of Some Novel Sulphur Substituted Chalcones as New Scaffold
    Mejo Joseph, S. Alaxander, J. Banurekha, Dr. Anandkumar · 2022 · International Journal of Life Science and Pharma Research
42. Pharmacological and Clinical Problems with Special Focus on Nasal Drug Delivery
    Misha Mathur, Yashwant Vishnupant Pathak · 2023 · Springer eBooks
43. Potential Targeting Sites to the Brain Through Nasal Passage
    Mershen Govender, Sunaina Indermun, Pradeep Kumar, Yahya Essop Choonara · 2023 · Springer eBooks
44. Nasal Drug Delivery Systems for the Treatment of Diseases of the Central Nervous System and Tuberculosis
    Thi Hong Nhung Vu, Svetlana Nikolaevna Morozkina, Петр Петрович Снетков, M. V. Uspenskaya · 2023 · Advanced clinical pharmacy - research, development and practical applications/Advanced clinical pharmacy - research, development and practical applications
45. Quality by Design based development and investigation of nasal polymeric micelles loaded with meloxicam
    Bence Sipos · 2023
46. Neuroprotective effect of intranasal delivery of asiatic acid against amyloid beta1-42-induced alzheimer's disease in mice
    Ridho Islamie, Ratchanee Rodsiri · 2022
47. Characterization of Nasal Spray Aerosol Fields Using the Extended Interference Particle Imaging Technique
    Tianhui Song, Qieni Lü, Hao Liu, Qingguo Tian · 2024 · SSRN Electronic Journal
48. To Explore Nasal-Brain Lymphatic System for Brain-Targeted Drug Delivery and to Treat Neurodegenerative Diseases
    Rohit Sharma, Monika, Bobby Tyagi, Disha Gupta, Rupa Mazumder, Avijit Mazumder · 2024 · Central Nervous System Agents in Medicinal Chemistry
49. A Review on Nose to Brain Drug Delivery Using Nanoparticles
    Mrunal K. Shirsat, Snehal Kadbhane, Vilas Rane, Rohan Bhandare, Shruti Warale · 2024 · International Journal of Advanced Research in Science Communication and Technology
50. Drug delivery systems
    Marcos Luciano Bruschi · 2025 · Elsevier eBooks
51. Multifunctional approaches of cubosome-integrated thermoresponsive gels for intranasal brain targeting: Innovations, therapeutic potential, and challenges
    Jyotika Das, Varnita Karmakar, Manisha Pandey, Neha Jain, Bapi Gorain · 2025 · Journal of Drug Delivery Science and Technology
52. Nucleic acid delivery : biocompatible yet efficient platforms
    M. Restrepo Carlos · 2015 · UCL Discovery (University College London)
53. Enhancing nasal retention: using the mucosal blanket to structure sprays
    Julie T.-W. Wang, Chi Wai Tsang, Nga Chi Yip, Shih-Che Hsu · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
54. Intranasal Delivery of Natural Compounds: A Promising approach for Parkinson’s Disease therapy
    Prakash D. Jadhav, Atish Baburao Velhal, Vivekkumar K. Redasani, Sanjivani T. Rathod · 2026 · Asian Journal of Pharmaceutical Research
55. In Situ Gellable Hydrogels for Nasal Drug Delivery
    Shima Ourani-Pourdashti, Seyedeh Mahya Marashiyan, Seyed Nasrollah Tabatabaei · 2026 · Springer eBooks
56. Intranasal Chitosan Nanoparticles for Direct Nose-to-Brain Delivery of Cariprazine: A Noninvasive Strategy for Targeted CNS Therapy
    Teja Kumar Ponduri, Chakravarthi Guntupalli, Balamurugan Jeganathan, Narender Malothu · 2026 · ACS Chemical Neuroscience
57. Intranasal administration of LNP-mRNA therapeutics
    Alok Raghav · 2026 · Elsevier eBooks
58. L-type amino acid transporter 1 targeting self-assembly polyelectrolyte nanocomplex with enhanced nose to brain delivery of oxytocin
    Yue Hu, Tiancong Liu, Yahan Zhang, Mengmeng Ding, Guang Shi, Haiying Su, Jian Guan, Xinyu Fan · 2026 · Journal of Controlled Release
59. Toxicité neuro-développementale d’une exposition gestationnelle à la pollution atmosphérique : effets à court et à long terme de l’inhalation répétée de particules de fumées de diesel chez le lapin
    Estefanía Bernal-Meléndez · 2019
60. An Interpretable, Thermodynamics-Based Deep Learning Framework for Predicting and Optimizing Drug Membrane Permeability
    Zhenyu Ma, Mengying Niu, Yuyang Song, L R Zhang, Wenxin Wang, Tengfei Wang, Jingyi Zhu, Chunyi Yang, Limei Xu, Xiuyun Wu et al. · 2026 · Journal of Medicinal Chemistry
61. De l'origine des maladies : la médecine environnementale : une nouvelle grille de lecture
    Jacques J. Reis · 2022
62. Intranasal Drug Delivery in Treating Alzheimer’s Disease
    Nitin Kumar, Harendar Kumar Nivatya, Arun Kumar Singh, Sonam, Lovy Sharma, Vishal Singh · 2026 · BENTHAM SCIENCE PUBLISHERS eBooks
63. Multimodal phototherapy for Glioblastoma: from mechanistic action to synergistic delivery and therapeutic strategies
    Gaurisha Alias Resha Ramnath Naik, Deepanjan Datta, Ritu R. Kudarha, Bhupendra Prajapati, Mital Patel, Varadharajan Srinivasan, Namdev L. Dhas · 2026 · Journal of Nanobiotechnology
64. Rational design of dual drug fingolimod salts as carrier-free nasal powders for potential nose-to-brain delivery in multiple sclerosis
    Minqi Fu, Yuehua Deng, Si Nga Wong, Xinyue Zhang, Kam‐Hung Low, Shing Fung Chow · 2026 · Journal of Drug Delivery Science and Technology
65. Intranasal Administration of a Self-Assembled Donepezil Nanocomplex for Targeted Brain Delivery and Improved Brain Pharmacokinetics in Rats
    Purushottam Shridhar Gangane, Mohammed Kaleem, Neha Kale, Sachin M. More, Gamal Osman Elhassan, Ameeduzzafar Zafar, Md Ali Mujtaba, Md. Khalid Anwer · 2026 · Journal of Pharmaceutical Innovation
66. Transnasal Zolmitriptan-Ginkgolide B loaded liposomes for migraine therapy: formulation, optimisation and in vitro characterisation
    Aparna Rajesh, Abhirami Subramony, R Nethish Kumaar, Siva Syam Kumar, Anand Biju, Sunij S Nair · 2026 · Journal of Liposome Research
67. Need for nanotherapeutics to combat neurodegenerative disorders
    Siddhant Kumar, Sumit Kumar, Rahul Shukla, Shubhini Awasthi Saraf · 2026 · Elsevier eBooks
68. Formulation and Optimization of Nose to Brain targeted system for Drug Delivery
    Rampal Singh, Dr.SURYA PRAKASH GUPTA, Gopal Garg · 2026 · Research Journal of Pharmacy and Technology
69. Nanocarrier-based intranasal drug delivery: A transformative strategy for brain-targeted epilepsy therapy
    Satyam Desai, Nisha S. Shirkoli, Rahul Koli · 2026 · JCIS Open
70. Pharmacokinetic Study of Intravenous Lomustine and Intranasal Lomustine-Loaded Solusome Nanovesicle in Rats for Brain Targeting
    Ihab Dahham Hammoodi, Nawal Ayash Rajab · 2026 · Al-Rafidain Journal of Medical Sciences
71. Optimized curcumin-loaded anionic niosomes for intranasal delivery: enhanced ex vivo nasal permeation and cytotoxicity against neuroblastoma
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72. Management of Badhirya (Sensorineural Hearing Loss) through Integrated Ayurvedic Interventions - A Case Study
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73. ROLE OF NASYA IN CERVICAL SPONDYLOSIS W.S.R. MANYASTAMBHA
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74. Nasal in-situ Transferosomes as a Platform Technology for Nose-to-Brain Drug Delivery
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75. Clinical insights: an update on transmucosal absorption with a focus on dodecyl maltoside
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76. Belief and bioavailability: a pharmacokinetically-driven analysis of Islamic fasting fatwas and its implications for clinical counselling
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77. Span60/Cholesterol Niosomal Formulation as a Transport Vehicle for L-DOPA and Rasagiline Delivery with Potent In Vitro Neuroprotective Effect
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78. Nose-to-Brain Therapeutics in Parkinson’s Disease: Clinical Trials, Mechanisms, and Therapeutic Potential
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79. Systematic Development of Pregabalin-Loaded Intranasal Thermosensitive In Situ Gel: In-Vitro Characterization, Ex-Vivo Safety and In-Vivo Efficacy Assessment Against Partial Epilepsy
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80. Chitosan-Based Nose-to-Brain Drug Delivery for Management of Neurological Disorders: Intrinsic Neuroprotective Action and Carrier Capabilities
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81. Intranasal Human Olfactory Mucosa-Derived Neural Stem Cells Restore Neuroplasticity and Suppress Neuroinflammation in a Rat Model of Chronic Stress-Induced Depression
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82. Vilazodone Hydrochloride-Loaded Nanostructured Lipid Carrier In Situ Gel for Intranasal Nose-to-Brain Antidepressant Delivery
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