The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Physical and Nutritional Prehabilitation in Older Patients With Colorectal Carcinoma: A Systematic Review
Open accessAbstract
Background and Purpose: Sarcopenia and malnourishment are highly prevalent in older patients with colorectal cancer (CRC), who form a growing group of patients at risk of adverse outcome after surgery. Intervention on physical function and/or nutritional status may decrease the risk of postoperative complications. However, the overall effect of preoperative physical and nutritional interventions (better known as prehabilitation) in older patients with CRC remains unknown. The objective was to review the literature on physical and nutritional prehabilitation performed as observational cohort studies or randomized controlled trials in patients 60 years and older undergoing elective CRC surgery. Methods: We searched PubMed, Embase.com, CINAHL, and the Cochrane Library from inception to July 16, 2015, for relevant literature. Search terms included colorectal cancer, aged, pre- and perioperative period, surgery, physical activity, and nutrition. Results: A total of 6 studies were included: 1 study applied a physical intervention, 3 studies applied a nutritional intervention, and 2 studies applied a combination of both interventions. None of the preoperative interventions significantly reduced length of stay, mortality, or readmission rates. Conclusions: Physical and nutritional prehabilitation in older patients with CRC has not shown a significant reduction in postoperative complications or length of stay. One study that examined the effect of a perioperative nutritional supplement reported a reduction in postoperative complications. Future research should explore targeted combined interventions, taking into account physical and nutritional patient requirements.
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“Older adults may require a more personalized approach to physical activity [33].”
From Pilot study of a telehealth perioperative physical activity intervention for older adults with cancer and their caregivers (2020) · cites this paper as [33]
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Metadata
- Authors
- Looijaard, S. M. L. M., Slee-Valentijn, M. S., Otten, R. H. J., & Maier, A. B.
- Affiliations
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- Department of Geriatric Rehabilitation, Cordaan, Amsterdam, the Netherlands.
- Vrije Universiteit Amsterdam (NL)
- The Royal Melbourne Hospital (AU)
- Corresponding author
- Maier, Andrea B.
- Venue
- Journal of Geriatric Physical Therapy
- Published
- 2018-10
- Volume
- 41
- Issue
- 4
- Pages
- 236-244
- ISSN
- 1539-8412 (ISSN-L)
- OpenAlex
- W2593451345
- Cited by
- 63
- References
- 45
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 10 · 2023: 4 · 2022: 7 · 2021: 8 · 2020: 11 · 2019: 6 · 2018: 5
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Geriatric Physical Therapy (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion, other-oa)
- VU Research Portal (publishedVersion, other-oa)
- Pure Amsterdam UMC (submittedVersion, cc-by)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- prehabilitation, colorectal cancer, elderly patients, sarcopenia, malnutrition, dietary intervention, physical activity, postoperative complications, length of hospital stay, colorectal surgery
- MeSH terms
- Aged, Aged, 80 and over, Diet, Humans, Middle Aged, Postoperative Complications, Colorectal Neoplasms, Exercise, Preoperative Period
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