The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Effect of Resistance Training to Muscle Failure vs. Volitional Interruption at High- and Low-Intensities on Muscle Mass and Strength
Abstract
Nóbrega, SR, Ugrinowitsch, C, Pintanel, L, Barcelos, C, and Libardi, CA. Effect of resistance training to muscle failure vs. volitional interruption at high- and low-intensities on muscle mass and strength. J Strength Cond Res 32(1): 162-169, 2018-The purpose of this study was to investigate the effects of resistance training (RT) at high- and low-intensities performed to muscle failure or volitional interruption on muscle strength, cross-sectional area (CSA), pennation angle (PA), and muscle activation. Thirty-two untrained men participated in the study. Each leg was allocated in 1 of 4 unilateral RT protocols: RT to failure at high and low intensities, and RT to volitional interruption (repetitions performed to the point in which participants voluntarily interrupted the exercise) at high (HIRT-V) and low (LIRT-V) intensities. Muscle strength (1 repetition maximum [1RM]), CSA, PA, and muscle activation by amplitude of the electromyography (EMG) signal were assessed before (Pre), after 6 (6W), and 12 (12W) weeks. 1RM increased similarly after 6W (range: 15.8-18.9%, effective size [ES]: 0.41-0.58) and 12W (range: 25.6-33.6%, ES: 0.64-0.98) for all protocols. All protocols were similarly effective in increasing CSA after 6W (range: 3.0-4.6%, ES: 0.10-0.24) and 12W (range: 6.1-7.5%, ES: 0.22-0.26). PA increased after 6W (∼3.5) and 12W (∼9%; main time effect, p < 0.0001), with no differences between protocols. EMG values were significantly higher for the high-intensity protocols at all times (main intensity effect, p < 0.0001). In conclusion, both HIRT-V and LIRT-V are equally effective in increasing muscle mass, strength, and PA when compared with RT performed to muscle failure.
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“Approaching failure may be useful insofar as it helps ensure full motor-unit recruitment and sufficient mechanotransduction [147].”
From Ribosome Biogenesis as a Putative Bottleneck to Skeletal Muscle Hypertrophy: Mechanisms, Human Evidence, and Practical Modulators (2026) · cites this paper as [147]
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Metadata
- Authors
- Nóbrega, S. R., Ugrinowitsch, C., Pintanel, L., Barcelos, C., & Libardi, C. A.
- Affiliations
- Universidade Federal de São Carlos (BR)
- Universidade de São Paulo (BR)
- Corresponding author
- Libardi, Cleiton A.
- Venue
- Journal of Strength and Conditioning Research
- Published
- 2018-01
- Volume
- 32
- Issue
- 1
- Pages
- 162-169
- ISSN
- 1064-8011 (ISSN-L)
- OpenAlex
- W2586947305
- Cited by
- 97
- References
- 46
- Citations by year
- 2026: 6 · 2025: 4 · 2024: 11 · 2023: 13 · 2022: 19 · 2021: 13 · 2020: 14 · 2019: 10 · 2018: 6
- FWCI
- 9.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Strength and Conditioning Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Strength and Conditioning Association
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Keywords
- resistance training, training to failure, exercise intensity, muscle strength, muscle mass, cross-sectional area, pennation angle, muscle activation, electromyography, one-repetition maximum, untrained men
- MeSH terms
- Adolescent, Adult, Electromyography, Humans, Male, Muscle, Skeletal, Muscle Strength, Resistance Training, Young Adult
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