The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Late-stage neuronal progenitors in the retina are radial Müller glia that function as retinal stem cells
Open accessAbstract
Neuronal progenitors in the mammalian brain derive from radial glia or specialized astrocytes. In developing neural retina, radial glia-like Müller cells are generated late in neurogenesis and are not considered to be neuronal progenitors, but they do proliferate after injury and can express neuronal markers, suggesting a latent neurogenic capacity. To examine the neurogenic capacity of retinal glial cells, we used lineage tracing in transgenic zebrafish with a glial-specific promoter (gfap, for glial fibrillary acid protein) driving green fluorescent protein in differentiated Müller glia. We found that all Müller glia in the zebrafish retina express low levels of the multipotent progenitor marker Pax6 (paired box gene 6), and they proliferate at a low frequency in the intact, uninjured retina. Müller glia-derived progenitors express Crx (cone rod homeobox) and are late retinal progenitors that generate the rod photoreceptor lineage in the postembryonic retina. These Müller glia-derived progenitors also remain competent to produce earlier neuronal lineages, in that they respond to loss of cone photoreceptors by specifically regenerating the missing neurons. We conclude that zebrafish Müller glia function as multipotent retinal stem cells that generate retinal neurons by homeostatic and regenerative developmental mechanisms.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The zebrafish retina is an important model for revealing these mechanisms since the retina is able to mount a robust regenerative response following injury and this response is dependent on the dedifferentiation of Müller glia (MG)”
From HB-EGF is Necessary and Sufficient for Müller Glia Dedifferentiation and Retina Regeneration (2012) · cites this paper as Bernardos et al., 2007
In the citing paper
“Key to successful retina regeneration are Müller glia (MG), the major glial cell-type in the retina (Bernardos et al., 2007; Fausett and Goldman, 2006; Fimbel et al., 2007).”
From Retinal injury, growth factors, and cytokines converge on β-catenin and pStat3 signaling to stimulate retina regeneration (2014) · cites this paper as Bernardos et al., 2007
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The zebrafish book : a guide for the laboratory use of zebrafish (Danio rerio)
Westerfield, M. (1995) · Medical Entomology and Zoology · Cited by 6,813
Mode of cell migration to the superficial layers of fetal monkey neocortex
Rakic, P. (1972) · Journal of Comparative Neurology · doi:10.1002/cne.901450105 · Cited by 2,170
The cell biology of neurogenesis
Götz, M., & Huttner, W. B. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1739 · Cited by 2,130
Neurons derived from radial glial cells establish radial units in neocortex
Noctor, S. C., Flint, A. C., Weissman, T. A., Dammerman, R. S., & Kriegstein, A. R. (2001) · Nature · doi:10.1038/35055553 · Cited by 2,016
Müller cells in the healthy and diseased retina
Bringmann, A., Pannicke, T., Grosche, J., Francke, M., Wiedemann, P., Skatchkov, S. N., Osborne, N. N., & Reichenbach, A. (2006) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2006.05.003 · Cited by 1,967
A common progenitor for neurons and glia persists in rat retina late in development
Turner, D. L., & Cepko, C. L. (1987) · Nature · doi:10.1038/328131a0 · Cited by 1,430
Álvarez-Buylla, A., & Lim, D. A. (2004) · Neuron · doi:10.1016/s0896-6273(04)00111-4 · Cited by 1,348
Vertebrate neural cell-fate determination: Lessons from the retina
Livesey, F. J., & Cepko, C. L. (2001) · Nature reviews. Neuroscience · doi:10.1038/35053522 · Cited by 948
Pax6 Is Required for the Multipotent State of Retinal Progenitor Cells
Marquardt, T., Ashery‐Padan, R., Andrejewski, N., Scardigli, R., Guillemot, F., & Gruß, P. (2001) · Cell · doi:10.1016/s0092-8674(01)00295-1 · Cited by 926
Radial Glia Serve as Neuronal Progenitors in All Regions of the Central Nervous System
Anthony, T. E., Klein, C., Fishell, G., & Heintz, N. (2004) · Neuron · doi:10.1016/s0896-6273(04)00140-0 · Cited by 852
Cited by
Sorted by citations
Items 201–300 of 637
The Retinal Homeobox (Rx) gene is necessary for retinal regeneration
Luna, R. I. M., Kelly, L. E., & El‐Hodiri, H. M. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.02.008 · Cited by 44
Taylor, S. M., Álvarez-Delfín, K., Saade, C. J., Thomas, J. L., Thummel, R., Fadool, J. M., & Hitchcock, P. F. (2015) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.15-17616 · Cited by 44
Rajaram, K., Harding, R. L., Bailey, T. J., Patton, J. G., & Hyde, D. R. (2014) · Developmental Dynamics · doi:10.1002/dvdy.24188 · Cited by 43
Raymond, P. A., Colvin, S. M., Jabeen, Z., Nagashima, M., Barthel, L. K., Hadidjojo, J., Popova, L., Pejaver, V. R., & Lubensky, D. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0085325 · Cited by 43
Self-citationUsing zebrafish as the model organism to understand organ regeneration
Shi, W., Fang, Z., Li, L., & Luo, L. (2015) · Science China Life Sciences · doi:10.1007/s11427-015-4838-z · Cited by 43
Zebrafish Models of Photoreceptor Dysfunction and Degeneration
Noel, N. C. L., MacDonald, I. M., & Allison, W. T. (2021) · Biomolecules · doi:10.3390/biom11010078 · Cited by 44
Neurodegeneration, Neuroprotection and Regeneration in the Zebrafish Retina
Stella, S., Geathers, J. S., Weber, S. R., Grillo, M. A., Barber, A. J., Sundstrom, J. M., & Grillo, S. L. (2021) · Cells · doi:10.3390/cells10030633 · Cited by 43
Bejarano‐Escobar, R., Blasco, M., DeGrip, W. J., Oyola‐Velasco, J., Martín‐Partido, G., & Francisco‐Morcillo, J. (2010) · Journal of Experimental Zoology Part B Molecular and Developmental Evolution · doi:10.1002/jez.b.21363 · Cited by 43
Ferretti, P. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07833.x · Cited by 45
Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis
de Melo, J., Clark, B. S., & Blackshaw, S. (2016) · Scientific Reports · doi:10.1038/srep32757 · Cited by 42
Purinergic signaling in the retina: From development to disease
Ventura, A. L. M., dos Santos‐Rodrigues, A., Mitchell, C. H., & Faillace, M. P. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.10.016 · Cited by 42
Ludwig, P. E., Freeman, S. C., & Janot, A. C. (2019) · International Journal of Retina and Vitreous · doi:10.1186/s40942-019-0158-y · Cited by 42
Essential genes for astroglial development and axon pathfinding during zebrafish embryogenesis
Barresi, M. J. F., Burton, S., DiPietrantonio, K., Amsterdam, A., Hopkins, N. H., & Karlstrom, R. O. (2010) · Developmental Dynamics · doi:10.1002/dvdy.22393 · Cited by 43
Rat BMSCs initiate retinal endogenous repair through NGF/TrkA signaling
Jian, Q., Li, Y., & Yin, Z. Q. (2015) · Experimental Eye Research · doi:10.1016/j.exer.2015.01.008 · Cited by 40
Battista, A. G., Ricatti, M. J., Pafundo, D. E., Gautier, M., & Faillace, M. P. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06352.x · Cited by 40
Neurotransmitter-Regulated Regeneration in the Zebrafish Retina
Rao, M. B., Didiano, D., & Patton, J. G. (2017) · Stem Cell Reports · doi:10.1016/j.stemcr.2017.02.007 · Cited by 40
Recapitulating developmental mechanisms for retinal regeneration
Ahmad, I., Teotia, P., Erickson, H. E., & Xia, X. (2019) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2019.100824 · Cited by 42
Adult Retinal Stem Cells Revisited
Bhatia, B., Singhal, S., Jayaram, H., Khaw, P. T., & Limb, G. A. (2010) · The Open Ophthalmology Journal · doi:10.2174/1874364101004010030 · Cited by 39
Emerging novel roles of neuropeptide Y in the retina: From neuromodulation to neuroprotection
Santos-Carvalho, A., Álvaro, A. R., Martins, J., Ambrósio, A. F., & Cavadas, C. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.10.002 · Cited by 39
Too, L. K., Gracie, G., Hasic, E., Iwakura, J. H., & Cherepanoff, S. (2017) · Acta Histochemica · doi:10.1016/j.acthis.2016.12.003 · Cited by 39
Epitranscriptomic m6A regulation following spinal cord injury
Xing, L., Cai, Y., Yang, T., Yu, W., Gao, M.-D., Chai, R., Ding, S., Wei, J., Pan, J., & Chen, G. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24763 · Cited by 39
Laranjeiro, R., & Whitmore, D. (2014) · Development · doi:10.1242/dev.104380 · Cited by 41
Calinescu, A., Vihtelic, T. S., Hyde, D. R., & Hitchcock, P. F. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.21999 · Cited by 39
Harnessing the Neuroprotective Behaviors of Müller Glia for Retinal Repair
Peña, J. S., & Vázquez, M. (2022) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2706169 · Cited by 40
Nomura-Komoike, K., Saitoh, F., & Fujieda, H. (2020) · Scientific Reports · doi:10.1038/s41598-020-58424-6 · Cited by 39
Kassen, S. C., Thummel, R., Burket, C. T., Campochiaro, L. A., Harding, M. J., & Hyde, D. R. (2008) · Europe PMC (PubMed Central) · Cited by 38
Nishiwaki, Y., Komori, A., Sagara, H., Suzuki, E., Manabe, T., Hosoya, T., Nojima, Y., Wada, H., Tanaka, H., Okamoto, H., et al. (2008) · Mechanisms of Development · doi:10.1016/j.mod.2008.09.001 · Cited by 38
Beach, K. M., Wang, J., & Otteson, D. C. (2017) · Stem Cells International · doi:10.1155/2017/1610691 · Cited by 39
Iribarne, M., Hyde, D. R., & Masai, I. (2019) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2019.00296 · Cited by 39
Müller glia–myeloid cell crosstalk accelerates optic nerve regeneration in the adult zebrafish
Dyck, A. V., Bollaerts, I., Beckers, A., Vanhunsel, S., Glorian, N., houcke, J. V., van Ham, T. J., Groef, L. D., Andries, L., & Moons, L. (2021) · Glia · doi:10.1002/glia.23972 · Cited by 39
Zhang, J., Wu, S., Jin, Z., & Wang, N. (2021) · Biomolecules · doi:10.3390/biom11070987 · Cited by 37
Reprogramming Retinal Pigment Epithelium to Differentiate Toward Retinal Neurons with Sox2
Ma, W., Yan, R., Li, X., & Wang, S. (2009) · Stem Cells · doi:10.1002/stem.48 · Cited by 37
McGinn, T. E., Mitchell, D. M., Meighan, P. C., Partington, N., Leoni, D. C., Jenkins, C. E., Varnum, M. D., & Stenkamp, D. L. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3444-16.2017 · Cited by 37
Effect of titanium dioxide nanoparticles on zebrafish embryos and developing retina.
Wang, Y., He, Z., Fang, Y., Xu, Y., Chen, Y., Wang, G.-Q., Yang, Y.-Q., Yang, Z. R., & Li, Y. (2014) · Europe PMC (PubMed Central) · doi:10.3980/j.issn.2222-3959.2014.06.01 · Cited by 37
Celotto, L., Rost, F., Machate, A., Bläsche, J., Dahl, A., Weber, A., Hans, S., & Brand, M. (2023) · eLife · doi:10.7554/elife.86507 · Cited by 36
Campbell, L. J., Willoughby, J. J., & Jensen, A. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051270 · Cited by 36
Kobat, S. G. (2020) · Beyoglu Eye Journal · doi:10.14744/bej.2020.28290 · Cited by 35
Fogerty, J., Song, P., Boyd, P., Grabinski, S. E., Hoang, T. V., Reich, A. M., Cianciolo, L. T., Blackshaw, S., Mumm, J. S., Hyde, D. R., et al. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.0244-22.2022 · Cited by 35
Müller Glia maintain their regenerative potential despite degeneration in the aged zebrafish retina
Martins, R. R., Zamzam, M. E., Tracey‐White, D., Moosajee, M., Thummel, R., Henriques, C. M., & MacDonald, R. B. (2022) · Aging Cell · doi:10.1111/acel.13597 · Cited by 35
Joachim, S. C., Wax, M. B., Seidel, P., Pfeiffer, N., & Grus, F. H. (2010) · Current Eye Research · doi:10.3109/02713683.2010.495829 · Cited by 35
Forbes-Osborne, M. A., Wilson, S. G., & Morris, A. C. (2013) · Developmental Biology · doi:10.1016/j.ydbio.2013.05.021 · Cited by 35
Reyes-Aguirre, L. I., & Lamas, M. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00523 · Cited by 35
Regenerative neurogenesis: the integration of developmental, physiological and immune signals
Becker, T., & Becker, C. G. (2022) · Development · doi:10.1242/dev.199907 · Cited by 36
Neuropeptide Y system in the retina: From localization to function
Santos-Carvalho, A., Ambrósio, A. F., & Cavadas, C. (2015) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2015.03.001 · Cited by 34
Bejarano‐Escobar, R., Blasco, M., Martín‐Partido, G., & Francisco‐Morcillo, J. (2012) · Journal of Experimental Biology · doi:10.1242/jeb.072124 · Cited by 34
Transcripts within rod photoreceptors of the Zebrafish retina
Sun, C., Galicia, C., & Stenkamp, D. L. (2018) · BMC Genomics · doi:10.1186/s12864-018-4499-y · Cited by 34
Cassar, S. C., Dunn, C., & Ramos, M. F. (2020) · Toxicologic Pathology · doi:10.1177/0192623320964748 · Cited by 34
Kubrusly, R. C. C., Panizzutti, R., Gardino, P. F., Stutz, B., Reis, R. A. D. M., Ventura, A. L. M., de Mello, M. C. F., & Mello, F. G. D. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.05.002 · Cited by 34
A Conditional Immortalized Mouse Müller Glial Cell Line Expressing Glial and Retinal Stem Cell Genes
Otteson, D. C., & Phillips, M. J. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-5395 · Cited by 34
Conditional and biased regeneration of cone photoreceptor types in the zebrafish retina
D’Orazi, F. D., Suzuki, S. C., Darling, N. J., Wong, R., & Yoshimatsu, T. (2020) · The Journal of Comparative Neurology · doi:10.1002/cne.24933 · Cited by 33
Tappeiner, C., Balmer, J., Iglicki, M., Schuerch, K., Jaźwińska, A., Enzmann, V., & Tschopp, M. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071064 · Cited by 33
Lgr5 + amacrine cells possess regenerative potential in the retina of adult mice
Chen, M., Tian, S., Glasgow, N. G., Gibson, G. A., Yang, X., Shiber, C., Funderburgh, J. L., Watkins, S. C., Johnson, J. W., Schuman, J. S., et al. (2015) · Aging Cell · doi:10.1111/acel.12346 · Cited by 32
Saade, C. J., Álvarez-Delfín, K., & Fadool, J. M. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2910-12.2013 · Cited by 32
Santhanam, A., Shihabeddin, E., Atkinson, J., Nguyen, D., Lin, Y., & O’Brien, J. (2020) · Cells · doi:10.3390/cells9102242 · Cited by 32
Kikel-Coury, N. L., Brandt, J. P., Correia, I. A., O’Dea, M. R., DeSantis, D. F., Sterling, F., Vaughan, K. T., Ozcebe, S. G., Zorlutuna, P., & Smith, C. J. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001444 · Cited by 36
Stem cell therapies for age-related macular degeneration: the past, present, and future
Dang, Y., Zhang, C., & Zhu, Y. (2015) · Clinical Interventions in Aging · doi:10.2147/cia.s73705 · Cited by 32
Xie, B., Zhang, X., Hashimoto, T., Tien, A. H., Chen, A., Ge, J., & Yang, X.-J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112175 · Cited by 32
Xie, S., Han, S., Qu, Z., Liu, F., Li, J., Yu, S., Reilly, J., Tu, J., Liu, X., Lu, Z., et al. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2019.01.022 · Cited by 33
Kara, N., Kent, M. R., Didiano, D., Rajaram, K., Zhao, A. H., Summerbell, E. R., & Patton, J. G. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.07.061 · Cited by 31
Mobilizing endogenous stem cells for retinal repair
Yu, H., Vu, T. H. K., Cho, K., Guo, C., & Chen, D. F. (2013) · Translational research · doi:10.1016/j.trsl.2013.11.011 · Cited by 31
Ramı́rez, M., & Lamas, M. (2009) · PubMed Central · Cited by 31
Cone Degeneration Following Rod Ablation in a Reversible Model of Retinal Degeneration
Choi, R. Y., Engbretson, G. A., Solessio, E. C., Jones, G. A., Coughlin, A. R., Aleksić, I., & Zuber, M. E. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-5347 · Cited by 30
Mitra, S., Devi, S., Lee, M., Jui, J., Sahu, A., & Goldman, D. J. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2211690119 · Cited by 30
Distinct and Conserved Prominin-1/CD133–Positive Retinal Cell Populations Identified across Species
Jászai, J., Fargeas, C. A., Graupner, S., Tanaka, E. M., Brand, M., Huttner, W. Β., & Corbeil, D. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017590 · Cited by 30
Prox1 expression in rod precursors and Müller cells
Cid, E., Santos‐Ledo, A., Parrilla, M., Lillo, C., Arévalo, R., Lara, J. M., Aijón, J., & Velasco, A. (2009) · Experimental Eye Research · doi:10.1016/j.exer.2009.10.015 · Cited by 29
Angbohang, A., Wu, N., Charalambous, T., Eastlake, K., Lei, Y., Kim, Y. S., Sun, X., & Limb, G. A. (2015) · Stem Cells and Development · doi:10.1089/scd.2015.0262 · Cited by 31
Müller Glial Cells Participate in Retinal Waves via Glutamate Transporters and AMPA Receptors
Zhang, R., Du, W., Prober, D. A., & Du, J. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.05.011 · Cited by 29
Differential Expression of Neuronal Genes in Müller Glia in Two- and Three-Dimensional Cultures
Phillips, M. J., & Otteson, D. C. (2010) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6400 · Cited by 29
Molecular characterization of cell types in the developing, mature, and regenerating fish retina
Bejarano‐Escobar, R., Blasco, M., Martín‐Partido, G., & Francisco‐Morcillo, J. (2013) · Reviews in Fish Biology and Fisheries · doi:10.1007/s11160-013-9320-z · Cited by 29
Nickerson, P. E. B., Silva, N. D., Myers, T. L., Stevens, K. T., & Clarke, D. B. (2008) · Brain Research · doi:10.1016/j.brainres.2008.03.095 · Cited by 29
Inhibition of the TGFβ Pathway Enhances Retinal Regeneration in Adult Zebrafish
Tappeiner, C., Maurer, E., Sallin, P., Bise, T., Enzmann, V., & Tschopp, M. (2016) · PLoS ONE · doi:10.1371/journal.pone.0167073 · Cited by 29
Neuhauss, S. C. F. (2010) · Fish physiology · doi:10.1016/s1546-5098(10)02903-1 · Cited by 30
Debbio, C. B. D., Mir, Q. A., Parameswaran, S., Mathews, S., Xia, X., Zheng, L. H., Neville, A. J., & Ahmad, I. (2016) · PLoS ONE · doi:10.1371/journal.pone.0152025 · Cited by 28
Eastlake, K., Heywood, W., Tracey‐White, D., Aquino, E., Bliss, E., Vasta, G. R., Mills, K. A., Khaw, P. T., Moosajee, M., & Limb, G. A. (2017) · Scientific Reports · doi:10.1038/srep44601 · Cited by 28
Campbell, W. A., Tangeman, A., El‐Hodiri, H. M., Hawthorn, E. C., Hathoot, M., Blum, S., Hoang, T. V., Blackshaw, S., & Fischer, A. J. (2022) · Development · doi:10.1242/dev.200127 · Cited by 28
Vertebrates That Regenerate As Models For Guiding Stem Cels
Antos, C. L., & Tanaka, E. M. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-7037-4_13 · Cited by 28
The expression and function of midkine in the vertebrate retina
Gramage, E., Li, J., & Hitchcock, P. F. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12495 · Cited by 28
Lu, C., & Hyde, D. R. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1406330 · Cited by 27
Imaging the eye as a window to brain health: frontier approaches and future directions
Banna, H. U., Slayo, M., Armitage, J. A., del Rosal, B., Giummarra, L., & Spencer, S. J. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03304-3 · Cited by 30
Towards stem cell-based neuronal regeneration for glaucoma
Hua, Z.-Q., Liu, H., Wang, N., & Jin, Z. (2020) · Progress in brain research · doi:10.1016/bs.pbr.2020.05.026 · Cited by 28
Investigating the genetics of visual processing, function and behaviour in zebrafish
Renninger, S. L., Schönthaler, H. B., Neuhauss, S. C. F., & Dahm, R. (2011) · Neurogenetics · doi:10.1007/s10048-011-0273-x · Cited by 28
Dvoriantchikova, G., Seemungal, R. J., & Ivanov, D. (2019) · Scientific Reports · doi:10.1038/s41598-019-40262-w · Cited by 28
Kang, S., Larbi, D., Andrade, M., Reardon, S., Reh, T. A., & Wohl, S. G. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.620459 · Cited by 28
Morrow, J. M., Lazic, S., Fox, M. D., Kuo, C., Schott, R. K., Gutierrez, E. D. A., Santini, F., Tropepe, V., & Chang, B. S. W. (2016) · Journal of Experimental Biology · doi:10.1242/jeb.145953 · Cited by 26
Ancient origin of the rod bipolar cell pathway in the vertebrate retina
Hellevik, A., Mardoum, P., Hahn, J., Kölsch, Y., D’Orazi, F. D., Suzuki, S. C., Godinho, L., Lawrence, O. T., Rieke, F. M., Shekhar, K., et al. (2024) · Nature Ecology & Evolution · doi:10.1038/s41559-024-02404-w · Cited by 26
Kugler, M., Schlecht, A., Fuchshofer, R., Kleiter, I., Aigner, L., Tamm, E. R., & Braunger, B. M. (2015) · Histochemistry and Cell Biology · doi:10.1007/s00418-015-1354-y · Cited by 26
Gramage, E., D’Cruz, T. S., Taylor, S. M., Thummel, R., & Hitchcock, P. F. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121789 · Cited by 26
Limb, G. A., & Martin, K. R. G. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6894 · Cited by 26
Cell differentiation in the retina of an epibenthonic teleost, the Tench (Tinca tinca, Linneo 1758)
Bejarano‐Escobar, R., Blasco, M., DeGrip, W. J., Martín‐Partido, G., & Francisco‐Morcillo, J. (2009) · Experimental Eye Research · doi:10.1016/j.exer.2009.04.007 · Cited by 26
miRNAs and Müller Glia Reprogramming During Retina Regeneration
Konar, G. J., Ferguson, C., Flickinger, Z., Kent, M. R., & Patton, J. G. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.632632 · Cited by 26
A role for DNA methylation in regulation of EphA5 receptor expression in the mouse retina
Petkova, T. D., Seigel, G. M., & Otteson, D. C. (2010) · Vision Research · doi:10.1016/j.visres.2010.09.022 · Cited by 26
DNA damage response in proliferating Müller glia in the mammalian retina
Nomura-Komoike, K., Saitoh, F., Komoike, Y., & Fujieda, H. (2016) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.15-18101 · Cited by 25
Müller cells trophism and pathology as the next therapeutic targets for retinal diseases
Arrigo, A., Cremona, O., Aragona, E., Casoni, F., Consalez, G., Dogru, R. M., Hauck, S. M., Antropoli, A., Bianco, L., Parodi, M. B., et al. (2025) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2025.101357 · Cited by 27
Adult Stem Cells, Tools for Repairing the Retina
Aladdad, A. M., & Kador, K. E. (2019) · Current Ophthalmology Reports · doi:10.1007/s40135-019-00195-z · Cited by 25
Yap Regulates Müller Glia Reprogramming in Damaged Zebrafish Retinas
Lourenço, R., Brandão, A. S., Borbinha, J., Gorgulho, R., & Jacinto, A. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.667796 · Cited by 25
Liu, F., Qin, Y., Huang, Y., Gao, P., Li, J., Yu, S., Jia, D., Chen, X. '., Lv, Y., Tu, J., et al. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1009841 · Cited by 25
Reprint of: The ciliary marginal zone (CMZ) in development and regeneration of the vertebrate eye
Fischer, A. J., Bosse, J. L., & El‐Hodiri, H. M. (2014) · Experimental Eye Research · doi:10.1016/j.exer.2014.04.019 · Cited by 25
Identification of Radial Glia Progenitors in the Developing and Adult Retina of Sharks
Sánchez-Farías, N., & Candal, E. (2016) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2016.00065 · Cited by 25
Characterization and Evolution of the Spotted Gar Retina
Sukeena, J. M., Galicia, C., Wilson, J. D., McGinn, T. E., BOUGHMAN, J. W., Robison, B. D., Postlethwait, J. H., Braasch, I., Stenkamp, D. L., & Fuerst, P. G. (2016) · Journal of Experimental Zoology Part B Molecular and Developmental Evolution · doi:10.1002/jez.b.22710 · Cited by 25
Stem cell-based therapies for age-related macular degeneration: current status and prospects.
Mu, Y., Zhao, M., & Su, G. (2014) · Europe PMC (PubMed Central) · Cited by 24
Metadata
- Authors
- Bernardos, R. L., Barthel, L. K., Meyers, J. R., & Raymond, P. A.
- Affiliations
- University of Michigan (US)
- Venue
- Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2007-06-27
- Volume
- 27
- Issue
- 26
- Pages
- 7028-7040
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6672216
- OpenAlex
- W2016508121
- Cited by
- 647
- References
- 60
- Citations by year
- 2026: 28 · 2025: 22 · 2024: 32 · 2023: 40 · 2022: 39 · 2021: 38 · 2020: 38 · 2019: 33 · 2018: 31 · 2017: 27 · 2016: 36 · 2015: 32 · 2014: 33 · 2013: 45 · 2012: 33
- FWCI
- 13.23
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neuroscience (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Eye Institute (R01EY004318, F32EY017251)
- National Institute of Neurological Disorders and Stroke (F31NS047909)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Development and Disorders
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- Müller cells, retinal stem cells, neuronal precursors, retinal neurogenesis, zebrafish retina, Pax6, CRX, rod photoreceptors, photoreceptor regeneration, glial fibrillary acidic protein, lineage tracing, retinal homeostasis, multipotent progenitors
- MeSH terms
- Aging, Animals, Cell Differentiation, Homeostasis, Neuroglia, Neurons, Regeneration, Retina, Species Specificity, Stem Cells, Zebrafish, Cell Lineage
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review