The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Dissociation Of Working Memory from Decision Making within the Human Prefrontal Cortex
Open accessAbstract
We tested the hypothesis that cognitive functions related to working memory (assessed with delay tasks) are distinct from those related to decision making (assessed with a gambling task), and that working memory and decision making depend in part on separate anatomical substrates. Normal controls (n= 21), subjects with lesions in the ventromedial (VM) (n= 9) or dorsolateral/high mesial (DL/M) prefrontal cortices (n= 10), performed on (1) modified delay tasks that assess working memory and (2) a gambling task designed to measure decision making. VM subjects with more anterior lesions (n= 4) performed defectively on the gambling but not the delay task. VM subjects with more posterior lesions (n= 5) were impaired on both tasks.Right DL/M subjects were impaired on the delay task but not the gambling task.Left DL/M subjects were not impaired on either task. The findings reveal a cognitive and anatomic double dissociation between deficits in decision making (anterior VM) and working memory (right DL/M). This presents the first direct evidence of such effects in humans using the lesion method and underscores the special importance of the VM prefrontal region in decision making, independent of a direct role in working memory.
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Citations
Cites
Insensitivity to future consequences following damage to human prefrontal cortex
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994) · Cognition · doi:10.1016/0010-0277(94)90018-3 · Cited by 6,128
Self-citationDeciding advantageously before knowing the advantageous strategy
Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1997) · Science · doi:10.1126/science.275.5304.1293 · Cited by 3,547
Self-citationThe somatic marker hypothesis and the possible functions of the prefrontal cortex
Damasio, A. R. (1996) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1996.0125 · Cited by 2,847 · cited 5×
“…another mechanism marks these various options and scenarios, which are temporarily held in working memory, with positive or negative values, and then from among this array of available options the most advantageous option is selected for action (Damasio et al., 1991; Damasio, 1994; Damasio, 1996).”
BackgroundInfluentialDEFICITS IN STRATEGY APPLICATION FOLLOWING FRONTAL LOBE DAMAGE IN MAN
SHALLICE, T., & BURGESS, P. W. (1991) · Brain · doi:10.1093/brain/114.2.727 · Cited by 2,017
Circuitry of Primate Prefrontal Cortex and Regulation of Behavior by Representational Memory
Goldman‐Rakic, P. S. (1987) · Comprehensive Physiology · doi:10.1002/cphy.cp010509 · Cited by 1,960
Temporal dynamics of brain activation during a working memory task
Cohen, J. D., Perlstein, W. M., Braver, T. S., Nystrom, L. E., Noll, D. C., Jonides, J., & Smith, E. E. (1997) · Nature · doi:10.1038/386604a0 · Cited by 1,876
Dissociation in prefrontal cortex of affective and attentional shifts
Dias, R., Robbins, T. W., & Roberts, A. C. (1996) · Nature · doi:10.1038/380069a0 · Cited by 1,527
Severe disturbance of higher cognition after bilateral frontal lobe ablation: Patient EVR
Eslinger, P. J., & Damasio, A. R. (1985) · Neurology · doi:10.1212/wnl.35.12.1731 · Cited by 1,426
DAMASIO, A. (1990) · Behavioural Brain Research · doi:10.1016/0166-4328(90)90144-4 · Cited by 1,275
McCarthy, G., Blamire, A. M., Puce, A., Nobre, A. C., Bloch, G., Hyder, F., Goldman-Rakic, P., & Shulman, R. G. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.18.8690 · Cited by 459
Cited by
Holroyd, C. B., & Coles, M. G. H. (2002) · Psychological Review · doi:10.1037/0033-295x.109.4.679 · Cited by 4,027
Emotion, Decision Making and the Orbitofrontal Cortex
Bechara, A. (2000) · Cerebral Cortex · doi:10.1093/cercor/10.3.295 · Cited by 3,589
Self-citationTrust in Automation: Designing for Appropriate Reliance
Lee, J. D., & See, K. A. (2004) · Human Factors: The Journal of the Human Factors and Ergonomics Society · doi:10.1518/hfes.46.1.50_30392 · Cited by 6,605
Common regions of the human frontal lobe recruited by diverse cognitive demands
Duncan, J., & Owen, A. M. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01633-7 · Cited by 2,498
Kane, M. J., & Engle, R. W. (2002) · Psychonomic Bulletin & Review · doi:10.3758/bf03196323 · Cited by 2,229
Metadata
- Authors
- Bechara, A., Damasio, H., Tranel, D., & Anderson, S. W.
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 1998-01-01
- Volume
- 18
- Issue
- 1
- Pages
- 428-437
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- OpenAlex
- W1654467375
- Cited by
- 1,059
- References
- 11
- FWCI
- 20.87
- Type
- journal article
- Language
- en
- Open access
- hybrid
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