The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens
Open accessAbstract
Comparative studies have implicated the nucleus accumbens (NAcc) in the anticipation of incentives, but the relative responsiveness of this neural substrate during anticipation of rewards versus punishments remains unclear. Using event-related functional magnetic resonance imaging, we investigated whether the anticipation of increasing monetary rewards and punishments would increase NAcc blood oxygen level-dependent contrast (hereafter, "activation") in eight healthy volunteers. Whereas anticipation of increasing rewards elicited both increasing self-reported happiness and NAcc activation, anticipation of increasing punishment elicited neither. However, anticipation of both rewards and punishments activated a different striatal region (the medial caudate). At the highest reward level ($5.00), NAcc activation was correlated with individual differences in self-reported happiness elicited by the reward cues. These findings suggest that whereas other striatal areas may code for expected incentive magnitude, a region in the NAcc codes for expected positive incentive value.
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“For primary (e.g., food) and secondary (e.g., money) rewards, striatum activity, as measured by blood oxygen level dependent (BOLD) fMRI signals, has been observed to increase when we encounter cues that predict a likely reward (e.g., a bell rung before mealtime 12, 13) and when we obtain a reward outcome (e.g., receive and consume the meal 14).”
From The social brain and reward: Social information processing in the human striatum (2014) · cites this paper as [12]
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“The ventral striatum has been implicated in reward-related processing in humans (Knutson, Adams, Fong, & Hommer, 2001; McClure, York, & Montague, 2004) and animals (Elliott, Friston, & Dolan, 2000).”
From Gender Differences in Emotion Regulation: An fMRI Study of Cognitive Reappraisal (2008) · cites this paper as Knutson, Adams, Fong, & Hommer, 2001
In the citing paper
“Nonclinical human neuroimaging studies indicate that the mesolimbic DA response to primary rewards may operate similarly in humans in response to more abstract, or secondary, rewards such as monetary incentives [98-100].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [99]
In the citing paper
“There are several other measures of impulsive decision-making, including delay aversion tasks or other methods of evaluating discounting of delayed rewards (Bitsakou et al., 2006, Knutson et al., 2001, Muller et al., 2006, Rachlin et al., 1991).”
From Characterizing heterogeneity in children with and without ADHD based on reward system connectivity (2015) · cites this paper as Knutson et al., 2001
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Cites
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913
Applied Linear Statistical Models
Ziegel, E. R., Neter, J., Wasserman, W., & Kutner, M. (1992) · Technometrics · doi:10.2307/1269588 · Cited by 9,906
A neural substrate of prediction and reward
Schultz, W., Dayan, P., & Montague, P. R. (1997) · Science · doi:10.1126/science.275.5306.1593 · Cited by 9,388
Applied Linear Statistical Models
Kutner, M., Nachtsheim, C. J., Neter, J., & Li, W. (1997) · Technometrics · doi:10.1080/00401706.1997.10485141 · Cited by 7,186
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
Abstract reward and punishment representations in the human orbitofrontal cortex
O'Doherty, J., Kringelbach, M. L., Rolls, E. T., Hornak, J., & Andrews, C. (2001) · Nature Neuroscience · doi:10.1038/82959 · Cited by 2,003
Response and Habituation of the Human Amygdala during Visual Processing of Facial Expression
Breiter, H. C., Etcoff, N. L., Whalen, P. J., Kennedy, W. A., Rauch, S. L., Buckner, R. L., Strauss, M. M., Hyman, S. E., & Rosen, B. R. (1996) · Neuron · doi:10.1016/s0896-6273(00)80219-6 · Cited by 1,711
Ikemoto, S., & Panksepp, J. (1999) · Brain Research Reviews · doi:10.1016/s0165-0173(99)00023-5 · Cited by 1,450
FMRI visualization of brain activity during a monetary incentive delay task
Knutson, B., Westdorp, A., Kaiser, E., & Hommer, D. (2000) · NeuroImage · doi:10.1006/nimg.2000.0593 · Cited by 1,414
Self-citationEvidence for striatal dopamine release during a video game
Koepp, M. J., Gunn, R. N., Lawrence, A. D., Cunningham, V. J., Dagher, A., Jones, T., Brooks, D. J., Bench, C. J., & Grasby, P. M. (1998) · Nature · doi:10.1038/30498 · Cited by 1,279
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The reward circuit: linking primate anatomy and human imaging
Haber, S. N., & Knutson, B. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.129 · Cited by 3,718
Self-citationCasey, B. J., Jones, R. M., & Hare, T. A. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.010 · Cited by 3,345
Relative Income, Happiness, and Utility: An Explanation for the Easterlin Paradox and Other Puzzles
Clark, A. E., Frijters, P., & Shields, M. A. (2008) · Journal of Economic Literature · doi:10.1257/jel.46.1.95 · Cited by 3,159
Self-referential processing in our brain—A meta-analysis of imaging studies on the self
Northoff, G., Heinzel, A., de Greck, M., Bermpohl, F., Dobrowolny, H., & Panksepp, J. (2006) · NeuroImage · doi:10.1016/j.neuroimage.2005.12.002 · Cited by 2,792
Bartra, O., McGuire, J. T., & Kable, J. W. (2013) · NeuroImage · doi:10.1016/j.neuroimage.2013.02.063 · Cited by 1,927
Metadata
- Authors
- Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D.
- Affiliations
- National Institutes of Health (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2001-08-15
- Volume
- 21
- Issue
- 16
- Pages
- RC159-RC159
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6763187
- OpenAlex
- W2119128116
- Cited by
- 2,244
- References
- 31
- Citations by year
- 2026: 56 · 2025: 73 · 2024: 46 · 2023: 91 · 2022: 80 · 2021: 73 · 2020: 97 · 2019: 96 · 2018: 115 · 2017: 96 · 2016: 140 · 2015: 128 · 2014: 147 · 2013: 123 · 2012: 134
- FWCI
- 18.34
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Neuroscience (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Keywords
- nucleus accumbens, reward anticipation, monetary rewards, incentive value, striatum, happiness, incentive magnitude, individual differences
- MeSH terms
- Adult, Brain Mapping, Caudate Nucleus, Cues, Female, Humans, Magnetic Resonance Imaging, Male, Nucleus Accumbens, Oxygen, Reward, Thalamus, Intuition
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