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Intra-Amygdala Blockade of the NR2B Subunit of the NMDA Receptor Disrupts the Acquisition But Not the Expression of Fear Conditioning
Open accessAbstract
The lateral nucleus of the amygdala (LA) is an essential component of the neural circuitry underlying Pavlovian fear conditioning. Although blockade of NMDA receptors in LA and adjacent areas before training disrupts the acquisition of fear conditioning, blockade before testing also often disrupts the expression of fear responses. With this pattern of results, it is not possible to distinguish a contribution of NMDA receptors to plasticity from a role in synaptic transmission. In past studies, NMDA blockade has been achieved using the antagonist d,l-2-amino-5-phosphovalerate, which blocks the entire heteromeric receptor complex. The present experiments examined the effects of selective blockade of the NR2B subunit of the NMDA receptor in LA using the selective antagonist ifenprodil. Systemic injections of ifenprodil before training led to a dose-dependent impairment in the acquisition of auditory and contextual fear conditioning, whereas injections before testing had no effect. Intra-amygdala infusions of ifenprodil mirrored these results and, in addition, showed that the effects are attributable to a disruption of fear learning rather than a disruption of memory consolidation. NMDA receptors in LA are thus involved in fear conditioning, and the NR2B subunit appears to make unique contributions to the underlying plasticity.
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“Several lines of indirect evidence support the idea that this plasticity occurs as a result of a Hebbian mechanism through which depolarization of LA pyramidal neurons by the shock US coincident with weaker activation of the same cells by auditory CS inputs results in fear learning (8–18).”
From Optical activation of lateral amygdala pyramidal cells instructs associative fear learning (2010) · cites this paper as [15]
In the citing paper
“Likewise, though the molecular mechanism of contextual fear extinction remains to be precisely determined, the N-methyl-D-aspartate (NMDA) receptor appears to play a critical role in fear extinction (Falls et al, 1992;Ledgerwood et al, 2003Ledgerwood et al, , 2004Ledgerwood et al, , 2005;;Rodrigues et al, 2001;Santini et al, 2001;Walker et al, 2002).”
From Effects of Single Prolonged Stress and D-Cycloserine on Contextual Fear Extinction and Hippocampal NMDA Receptor Expression in a Rat Model of PTSD (2008) · cites this paper as Rodrigues et al, 2001
Citations
Cites
A synaptic model of memory: long-term potentiation in the hippocampus
Bliss, T. V. P., & Collingridge, G. L. (1993) · Nature · doi:10.1038/361031a0 · Cited by 11,566
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Self-citationHollmann, M., & Heinemann, S. F. (1994) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.17.030194.000335 · Cited by 4,056
Long-Term Potentiation--A Decade of Progress?
Malenka, R. C., & Nicoll, A. R. A. (1999) · Science · doi:10.1126/science.285.5435.1870 · Cited by 2,729
Molecular diversity of glutamate receptors and implications for brain function
Nakanishi, S. (1992) · Science · doi:10.1126/science.1329206 · Cited by 2,543
Genetic enhancement of learning and memory in mice
Tang, Y., Shimizu, E., Dubé, G., Rampon, C., Kerchner, G. A., Zhuo, M., Liu, G., & Tsien, J. Z. (1999) · Nature · doi:10.1038/43432 · Cited by 1,878
Control of memory formation through regulated expression of a CaMKII transgene
Mayford, M., Bach, M. E., Huang, Y.-Y., Wang, L., Hawkins, R. D., & Kandel, E. R. (1996) · Science · doi:10.1126/science.274.5293.1678 · Cited by 1,550
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
Sheng, M., Cummings, J., Roldan, L. A., Jan, Y. N., & Jan, L. Y. (1994) · Nature · doi:10.1038/368144a0 · Cited by 1,377
Autophosphorylation at Thr 286 of the α Calcium-Calmodulin Kinase II in LTP and Learning
Giese, K. P., Fedorov, N. B., Filipkowski, R. K., & Silva, A. J. (1998) · Science · doi:10.1126/science.279.5352.870 · Cited by 1,055
Why We Think Plasticity Underlying Pavlovian Fear Conditioning Occurs in the Basolateral Amygdala
Fanselow, M. S., & LeDoux, J. E. (1999) · Neuron · doi:10.1016/s0896-6273(00)80775-8 · Cited by 933
Self-citation
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Wang, C., Yang, Y., Zhang, J., Liu, J., Guan, X., Li, M., Lu, H., Wu, P., Chen, J., & Wang, F. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12961 · Cited by 25
Traces of memory: reacquisition of fear following forgetting is NMDAr-independent
Li, S., & Richardson, R. (2013) · Learning & Memory · doi:10.1101/lm.029504.112 · Cited by 24
Valizadegan, F., Oryan, S., Nasehi, M., & Zarrindast, M. (2013) · PubMed · Cited by 24
Deciphering Memory Function with Optogenetics
Beyeler, A., Eckhardt, C. A., & Tye, K. M. (2014) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-420170-5.00012-x · Cited by 24
A role for nitric oxide-driven retrograde signaling in the consolidation of a fear memory
Overeem, K. A. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/neuro.08.002.2010 · Cited by 24
Fear memory and the amygdala: insights from a molecular perspective
Stork, O., & Pape, H. (2002) · Cell and Tissue Research · doi:10.1007/s00441-002-0656-2 · Cited by 23
Maffucci, J. A., Walker, D. M., Ikegami, A., Woller, M. J., & Gore, A. C. (2007) · Neuroendocrinology · doi:10.1159/000111136 · Cited by 22
Lindquist, D. H., & Brown, T. H. (2004) · Behavioral Neuroscience · doi:10.1037/0735-7044.118.1.36 · Cited by 22
Bertotto, M. E., Maldonado, N. M., Bignante, E. A., Gorosito, S. V., Cambiasso, M. J., Molina, V. A., & Martijena, I. D. (2011) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.01.001 · Cited by 22
de Oliveira, D. R., Sanada, P. F., Filho, A. C., Conceição, G. M. S., Cerutti, J. M., & Cerutti, S. M. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.01.009 · Cited by 21
Allosteric Changes in the NMDA Receptor Associated with Calcium-Dependent Inactivation
Bhatia, N. K., Carrillo, E. C., Durham, R. J., Berka, V., & Jayaraman, V. (2020) · Biophysical Journal · doi:10.1016/j.bpj.2020.08.045 · Cited by 19
The role of GluN2B-containing NMDA receptors in short- and long-term fear recall
Mikics, É., Tóth, M., Bíró, L., Bruzsik, B., Nagy, B. R., & Haller, J. (2017) · Physiology & Behavior · doi:10.1016/j.physbeh.2017.04.005 · Cited by 20
Effects of pre- or post-training entorhinal cortex AP5 injection on fear conditioning
Schenberg, E. E., Soares, J. C. K., & MENEZESOLIVEIRA, M. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.08.032 · Cited by 20
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Lissek, S., & Güntürkün, O. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.01.007 · Cited by 25
Williams-Spooner, M. J., Delaney, A., Westbrook, R. F., & Holmes, N. M. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.2156-21.2022 · Cited by 24
Beyond appetite: Acylated ghrelin as a learning, memory and fear behavior-modulating hormone
Reich, N., & Hölscher, C. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104952 · Cited by 20
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Lokshina, Y., Sheynin, J., Vogt, G. S., & Liberzon, I. (2023) · Current topics in behavioral neurosciences · doi:10.1007/7854_2023_436 · Cited by 19
Adkins, J. M., Lynch, J. F., Hagerdorn, P. L., Esterhuizen, M., & Jasnow, A. M. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.05.009 · Cited by 21
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Moscarello, J. M., & LeDoux, J. E. (2014) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2014.79.024968 · Cited by 24
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Fernandes, G., Mishra, P. K., Nawaz, M. S., Donlin-Asp, P., Rahman, M. M., Hazra, A., Kedia, S., Kayenaat, A., Songara, D., Wyllie, D. J. A., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109805 · Cited by 19
Szumlinski, K. K., Wroten, M. G., Miller, B. W., Sacramento, A. D., Cohen, M., Ben‐Shahar, O., & Kippin, T. E. (2016) · Journal of Drug Abuse · doi:10.21767/2471-853x.100022 · Cited by 18
Zhang, J., Lu, X., Wang, X., Li, W., & Du, J. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20860 · Cited by 19
Tsang, K. H., Lai, S., Li, Q., Yung, W., Liu, H., Mak, P. H. S., Ng, C. C. P., McAlonan, G. M., Chan, Y., & Chan, S. Y. (2014) · Scientific Reports · doi:10.1038/srep03654 · Cited by 20
Jo, Y. S., & Choi, J.-S. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.11.004 · Cited by 17
Delaney, A., Power, J., & Sah, P. (2011) · Journal of Neurophysiology · doi:10.1152/jn.01066.2011 · Cited by 17
Effect of context exposure after fear learning on memory generalization in mice
Fujinaka, A., Li, R., Hayashi, M., Kumar, D., Changarathil, G., Naito, K., Miki, K., Nishiyama, T., Lazarus, M., Sakurai, T., et al. (2016) · Molecular Brain · doi:10.1186/s13041-015-0184-0 · Cited by 17
Pharmacological rewriting of fear memories: A beacon for post-traumatic stress disorder
Uniyal, A., Singh, R., Akhtar, A., Dhaliwal, J., Kuhad, A., & Sah, S. P. (2019) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2019.172824 · Cited by 19
Wen, J.-L., Li, X., Wang, R., Chen, Z.-X., Shi, Y., & Zhao, H. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.10.049 · Cited by 17
5-HT1A receptor activation reduces fear-related behavior following social defeat in Syrian hamsters
Bader, L. R., Carboni, J. D., Burleson, C. A., & Cooper, M. A. (2014) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2014.03.024 · Cited by 17
Dulka, B. N., Ford, E. C., Lee, M. A., Donnell, N. J., Goode, T. D., Prosser, R. A., & Cooper, M. A. (2016) · Learning & Memory · doi:10.1101/lm.040253.115 · Cited by 19
Farrell, K., Musaus, M., Auerbach, A., Navabpour, S., Ray, W. K., Helm, R. F., & Jarome, T. J. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-02112-0 · Cited by 15
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Leppla, C. A., Keyes, L. R., Glober, G. F., Matthews, G. A., Batra, K., Jay, M., Feng, Y., Chen, H. S., Mills, F., Delahanty, J., et al. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06284-5 · Cited by 16
Ferrara, N. C., Mrackova, E., Loh, M. K., Padival, M., & Rosenkranz, J. A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21083008 · Cited by 14
Gene therapy in rodent amygdala against fear disorders
Mitra, R., & Sapolsky, R. M. (2010) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2010.509341 · Cited by 14
The role of telencephalic NO and cGMP in avoidance conditioning in goldfish (Carassius auratus).
Xu, X., Bentley, J., Miller, T., Zmolek, K., Kovaleinen, T., Goodman, E., & Foster, T. (2009) · Behavioral Neuroscience · doi:10.1037/a0015243 · Cited by 13
Sepahvand, T., Power, K. D., Qin, T., & Yuan, Q. (2023) · Biology · doi:10.3390/biology12101274 · Cited by 17
Park, S., Lee, S., Kim, J., & Choi, S. (2012) · Neuroscience Letters · doi:10.1016/j.neulet.2012.10.011 · Cited by 15
Modulation of fear memory by retrieval and extinction: a clue for memory deconsolidation
Hong, I., Kim, J., Song, B., Park, S., Lee, J., Kim, J., An, B., Lee, S., & Choi, S. (2011) · Reviews in the Neurosciences · doi:10.1515/rns.2011.023 · Cited by 13
Zheng, J., Wu, X. H., & Li, L. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.10.027 · Cited by 13
Steinmetz, A. B., Ng, K. H., & Freeman, J. H. (2017) · Learning & Memory · doi:10.1101/lm.045310.117 · Cited by 13
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Chan, D., Baker, K., & Richardson, R. (2014) · Physiology & Behavior · doi:10.1016/j.physbeh.2014.11.004 · Cited by 12
Apparent reconsolidation interference without generalized amnesia
Alfei, J. M., Gruy, H. D., Bundel, D. D., Luyten, L., & Beckers, T. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.110161 · Cited by 12
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Duman, C. H., & Duman, R. S. (2005) · Handbook of experimental pharmacology · doi:10.1007/3-540-28082-0_11 · Cited by 13
Anxiety and the brain: Neuropeptides as emerging factors
Satao, K. S., & Doshi, G. (2024) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2024.173878 · Cited by 12
Kincheski, G. C., & Carobrez, A. P. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.09.001 · Cited by 11
Huang, J., Wu, X. H., Yeomans, J. S., & Li, L. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04030.x · Cited by 11
Neural and Molecular Mechanisms of Fear Memory
Schafe, G. E., & LeDoux, J. E. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00045-0 · Cited by 11
Self-citationKeidar, T., Williams-Spooner, M. J., Wong, F. S., Westbrook, R. F., & Holmes, N. M. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0067-23.2023 · Cited by 10
Duan, Y., Zhou, S., Ma, J., Yin, P., & Cao, X. (2015) · European Journal of Neuroscience · doi:10.1111/ejn.13008 · Cited by 10
Long-Term Potentiation and Memory
(2012) · Springer eBooks · doi:10.1007/springerreference_169302 · Cited by 10
Heroux, N. A., Robinson-Drummer, P. A., Rosen, J. B., & Stanton, M. E. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.12.025 · Cited by 9
Combining d-cycloserine and exposure-based CBT for the anxiety disorders.
Deveney, C. M., McHugh, R. K., Tolin, D. F., Pollack, M. H., & Otto, M. W. (2009) · Cited by 9
Miu, A. C., Olteanu, A. I., Chiş, I. C., & Heilman, R. M. (2004) · Behavioural Brain Research · doi:10.1016/j.bbr.2004.04.019 · Cited by 9
Inhibitory and Excitatory Circuitries in Amygdala Nuclei
Rainnie, D. G. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07071.x · Cited by 9
Integration of sensory and fear memories in the rat medial temporal lobePreprint
Wong, F. S., Thomas, A. B., Killcross, S., Laurent, V., Westbrook, R. F., & Holmes, N. M. (2024) · eLife · doi:10.7554/elife.101965 · Cited by 11
Kong, C. H., Min, H. S., Jeon, M., Kang, W. C., Park, K., Kim, M. S., Jung, S. Y., Bae, H. J., Park, S. J., Shin, H., et al. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118270 · Cited by 8
Khakpoor, M., Nasehi, M., Vahdati, A., Hoseyni, S.-E., & Zarrindast, M. (2016) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2016.02.001 · Cited by 8
Kishioka, A., Uemura, T., Fukushima, F., & Mishina, M. (2013) · Molecular Brain · doi:10.1186/1756-6606-6-17 · Cited by 8
LaRese, T. P., Yan, Y., Eipper, B. A., & Mains, R. E. (2017) · BMC Neuroscience · doi:10.1186/s12868-017-0363-2 · Cited by 8
Shen, G., & Tietz, E. I. (2010) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.110.174235 · Cited by 8
Kubota, O., Hattori, K., Hashimoto, K., Yagi, T., Sato, T., Iyo, M., & Yuasa, S. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.07.018 · Cited by 8
Neural systems involved in fear and anxiety based on the fear-potentiated startle test
Davis, M. (2007) · Elsevier eBooks · doi:10.1016/b978-012372540-0/50013-3 · Cited by 6
Regulation of learned fear expression through the MgN-amygdala pathway
Ferrara, N. C., Trask, S., Pullins, S. E., & Helmstetter, F. J. (2021) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2021.107526 · Cited by 7
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Bertocchi, I., Rocha-Almeida, F., Romero-Barragán, M. T., Cambiaghi, M., Carretero‐Guillén, A., Botta, P., Dogbevia, G., Treviño, M., Mele, P., Oberto, A., et al. (2023) · iScience · doi:10.1016/j.isci.2023.108050 · Cited by 6
Overeem, K. A., & Kokkinidis, L. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.10.001 · Cited by 6
Agarwal, K., Farhat, A., & Lamprecht, R. (2024) · Communications Biology · doi:10.1038/s42003-024-06844-9 · Cited by 6
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Chaillan, F. A., Truchet, B., & Roman, F. S. (2008) · Journal of Integrative Neuroscience · doi:10.1142/s0219635208001794 · Cited by 4
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Sørensen, C. (2005) · NORA - Norwegian Open Research Archives · Cited by 5
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Shin, R.-M. (2012) · InTech eBooks · doi:10.5772/48397 · Cited by 4
Wang, J., Han, J., Wang, S., Duan, Y., Bao, C., Luo, Y., Xue, Q., & Cao, X. (2021) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2021.05.023 · Cited by 5
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Grant, S. G. N., Husi, H., Choudhary, J. S., Cumiskey, M. A., Blackstock, W. P., & Armstrong, J. D. (2003) · Springer eBooks · doi:10.1007/978-1-4615-0039-1_2 · Cited by 4
Maren, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.21090-0 · Cited by 5
Neural Basis of Fear Conditioning
Bush, D. E. A., Schafe, G. E., & LeDoux, J. E. (2009) · Wiley eBooks · doi:10.1002/9780470478509.neubb002039 · Cited by 4
Self-citationTaugher, R. J., Berns, A., Jones, M., Townsend, A., Eagen, A. K., Ferri, S. L., Langbehn, D. R., & Janouschek, H. (2025) · Autism Research · doi:10.1002/aur.70034 · Cited by 3
Procedural Learning: Classical Conditioning
Poulos, A. M., Christian, K. M., & Thompson, R. F. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00121-2 · Cited by 4
Xin-Qiu, L. I. U. (2005) · Chinese Science Bulletin · doi:10.1360/982005-897 · Cited by 3
Fear Conditioning and Extinction as a Model of PTSD in Mice
Gafford, G. M., & Ressler, K. J. (2011) · Neuromethods · doi:10.1007/978-1-61779-313-4_11 · Cited by 3
Fear learning-induced changes in AMPAR and NMDAR expression in the fear circuitPreprint
Shultz, B., Farkash, A., Collins, B., Mohammadmirzaei, N., & Knox, D. (2022) · Learning & Memory · doi:10.1101/lm.053525.121 · Cited by 3
ASPECTOS NEUROBIOLÓGICOS IMPLICADOS EN EL MIEDO ANIMAL
Sánchez-Ramírez, J. D., & Uribe-Velásquez, L. F. (2009) · Biosalud · Cited by 2
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Castro-Sierra, E., de León, F. C.-P., & Rivera, A. P. (2005) · Redalyc (Universidad Autónoma del Estado de México) · Cited by 2
Role of long-term potentiation in mechanism of the conditioned learning
Tsvetkov, E., Suderevskaya, E. I., & Vesselkin, N. P. (2011) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093011030017 · Cited by 2
The Influence of Diet and the Gut Microbiota in Schizophrenia
Ghomi, R. H., & Nemani, K. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802304-4.00016-5 · Cited by 2
Schafe, G. E. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-415804-7.00013-7 · Cited by 4
Self-citationMaren, S. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00129-7 · Cited by 2
From non-pharmacological interventions to therapeutic targets for the treatment of PTSD
Hendriksen, H. M. A. (2012) · Utrecht University Repository (Utrecht University) · Cited by 2
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Schafe, G. E., & LeDoux, J. E. (2006) · Springer eBooks · doi:10.1007/978-0-387-30405-2_18 · Cited by 2
Self-citationOvereem, K. A. (2006) · UC Research Repository (University of Canterbury) · doi:10.26021/8719 · Cited by 2
Second-order threat conditioning in the amygdala-posterior piriform cortex network
Sepahvand, T., Qin, T., Hasan, Z., Power, K. D., Carew, S. J., Nazari, N., Janes, A. M., Salman, A., Xia, Y., Benoukraf, T., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-08287-2 · Cited by 1
Glutamatergic synapses serve as potential targets for controlling persistent pain
Robinson, D. A., & Zhuo, M. (2002) · Current Anaesthesia and Critical Care · doi:10.1054/cacc.2003.0430 · Cited by 1
Neuropsychologische Schlüsselprobleme der Musiktherapie
Mastnak, W. (2013) · Musik- Tanz- und Kunsttherapie · doi:10.1026/0933-6885/a000103 · Cited by 1
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Chen, Y. (2019) · E3S Web of Conferences · doi:10.1051/e3sconf/201913101007 · Cited by 1
Shuvalov, O. Y., Kizenko, A., Petukhov, A., Parfenyev, S. V., Fedorova, O., Daks, A. A., & Barlev, N. A. (2020) · Cell and Tissue Biology · doi:10.1134/s1990519x20020108 · Cited by 1
Fear conditioning- and extinction-induced neuronal plasticity in the mouse amygdala
Ciocchi, S. (2009) · edoc (University of Basel) · doi:10.5451/unibas-004840917 · Cited by 1
Schafe, G. E., & LeDoux, J. E. (2002) · Wiley eBooks · doi:10.1002/0471214426.pas0313 · Cited by 1
Self-citationDistribution of NMDA and AMPA receptor subunits at thalamo-amygdaloid dendritic spines
Radley, J. J., Farb, C. R., He, Y., Janssen, W. G. M., Rodrigues, S. M., Johnson, L. R., Hof, P. R., LeDoux, J. E., & Morrison, J. H. (2007) · Brain Research · doi:10.1016/j.brainres.2006.11.045
Self-citationThe role of CaMKII binding NMDARs in synaptic plasticity and memory
Dallapiazza, R. F. (2010) · doi:10.17077/etd.ut2qb8ib
Anxiety and Fear Conditioning, Neural Basis of
Roquet, R. F., & Monfils, M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-08-097086-8.55002-8
Metadata
- Authors
- Rodrigues, S. M., Schafe, G. E., & LeDoux, J. E.
- Affiliations
- W. M. Keck Foundation (US)
- New York University (US)
- ORCID
- LeDoux, Joseph E.
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2001-09-01
- Volume
- 21
- Issue
- 17
- Pages
- 6889-6896
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6763096
- OpenAlex
- W2108961156
- Cited by
- 350
- References
- 55
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 9 · 2023: 6 · 2022: 4 · 2021: 5 · 2020: 9 · 2019: 5 · 2018: 5 · 2017: 8 · 2016: 14 · 2015: 15 · 2014: 19 · 2013: 23 · 2012: 16
- FWCI
- 8.60
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Neuroscience (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- W. M. Keck Foundation
- York University
- National Institute of Mental Health (MH-58911, R37MH038774, P50MH058911, R01MH046516)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- NMDA receptor, NR2B subunit, ifenprodil, lateral amygdala, fear conditioning, fear acquisition, fear expression, memory consolidation, synaptic plasticity, auditory fear conditioning, contextual fear conditioning, NMDA receptor antagonism
- MeSH terms
- Acoustic Stimulation, Amygdala, Animals, Conditioning, Classical, Dose-Response Relationship, Drug, Drug Administration Schedule, Electroshock, Fear, Injections, Intraperitoneal, Learning, Male, Memory, Short-Term, Microinjections, Piperidines, Retention, Psychology, Receptors, N-Methyl-D-Aspartate, Rats, Sprague-Dawley, Excitatory Amino Acid Antagonists, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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