Molecular diversity of glutamate receptors and implications for brain function

Cloning of a novel glutamate receptor subunit, GluR5: Expression in the nervous system during development

Bettler, B., Boulter, J., Hermans-Borgmeyer, I., O'Shea-Greenfield, A., Deneris, E. S., Moll, C., Borgmeyer, U., Hollmann, M., & Heinemann, S. (1990) · Neuron · doi:10.1016/0896-6273(90)90213-y · Cited by 649 · see citing works

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory.

Tsien, J. Z., Huerta, P. T., & Tonegawa, S. (1996) · Cell · doi:10.1016/s0092-8674(00)81827-9 · Cited by 1,782 · see citing works

Mammalian sweet taste receptors

Nelson, G., Hoon, M. A., Chandrashekar, J., Zhang, Y., Ryba, N. J. P., & Zuker, C. S. (2001) · Cell · doi:10.1016/s0092-8674(01)00451-2 · Cited by 1,702 · see citing works

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

Baude, A., Nusser, Z., Roberts, J. D. B., Mulvihill, E., Jeffrey Mcllhinney, R. A., & Somogyi, P. (1993) · Neuron · doi:10.1016/0896-6273(93)90086-7 · Cited by 927 · see citing works

Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond

Lipton, S. A. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd1958 · Cited by 909 · see citing works

Regulation of Neurotransmitter Release by Metabotropic Glutamate Receptors

Cartmell, J., & Schoepp, D. D. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0750889.x · Cited by 883 · see citing works

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.

Aiba, A. (1994) · Cell · doi:10.1016/0092-8674(94)90204-6 · Cited by 614 · see citing works

Synaptic plasticity in the lateral amygdala: a cellular hypothesis of fear conditioning

Blair, H. T., Schafe, G. E., Bauer, E. P., Rodrigues, S. M., & LeDoux, J. E. (2001) · Learning & Memory · doi:10.1101/lm.30901 · Cited by 610 · see citing works

The Glutamatergic Dysfunction Hypothesis for Schizophrenia

Coyle, J. T. (1996) · Harvard Review of Psychiatry · doi:10.3109/10673229609017192 · Cited by 568 · see citing works

Nongenomic steroid action: controversies, questions, and answers

LÖSEL, R. M., FALKENSTEIN, E., FEURING, M., SCHULTZ, A., TILLMANN, H.-C., ROSSOL-HASEROTH, K., & WEHLING, M. (2003) · Physiological Reviews · doi:10.1152/physrev.00003.2003 · Cited by 561 · see citing works

Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited

Keshavan, M. S., Anderson, S., & Pettergrew, J. W. (1994) · Journal of Psychiatric Research · doi:10.1016/0022-3956(94)90009-4 · Cited by 525 · see citing works

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

Forrest, D., Yuzaki, M., Soares, H. D., Ng, L., Luk, D. C., Sheng, M., Stewart, C. L., Morgan, J. I., Connor, J. A., & Curran, T. (1994) · Neuron · doi:10.1016/0896-6273(94)90350-6 · Cited by 491 · see citing works

Stargazin modulates AMPA receptor gating and trafficking by distinct domains

Tomita, S., Adesnik, H., Sekiguchi, M., Zhang, W., Wada, K., Howe, J. R., Nicoll, R. A., & Bredt, D. S. (2005) · Nature · doi:10.1038/nature03624 · Cited by 486 · see citing works

Molecular mechanisms underlying emotional learning and memory in the lateral amygdala

Rodrigues, S. M., Schafe, G. E., & LeDoux, J. E. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.014 · Cited by 491 · see citing works

A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission

Clarke, V. R. J., Ballyk, B. A., Hoo, K. H., Mandelzys, A., Pellizzari, A., Bath, C. P., Thomas, J., Sharpe, E. F., Davies, C. H., Ornstein, P. L., et al. (1997) · Nature · doi:10.1038/39315 · Cited by 416 · see citing works

Quinolinic acid: an endogenous neurotoxin with multiple targets

Lugo-Huitrón, R., Ugalde Muñiz, P., Pineda, B., Pedraza-Chaverrí, J., Ríos, C., & Pérez-de la Cruz, V. (2013) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2013/104024 · Cited by 394 · see citing works

Chapter 6 Glutamate receptors and the induction of excitotoxic neuronal death

Choi, D. W. (1994) · Progress in Brain Research · doi:10.1016/s0079-6123(08)60767-0 · Cited by 385 · see citing works

Hormones and the physiological architecture of life history evolution

Finch, C. E., & Rose, M. R. (1995) · The Quarterly Review of Biology · doi:10.1086/418864 · Cited by 376 · see citing works

Intra-Amygdala Blockade of the NR2B Subunit of the NMDA Receptor Disrupts the Acquisition But Not the Expression of Fear Conditioning

Rodrigues, S. M., Schafe, G. E., & LeDoux, J. E. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-17-06889.2001 · Cited by 350 · see citing works

Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment

Konradi, C., & Heckers, S. (2003) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(02)00328-5 · Cited by 336 · see citing works

MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity

Chaki, S., Yoshikawa, R., Hirota, S., Shimazaki, T., Maeda, M., Kawashima, N., Yoshimizu, T., Yasuhara, A., Sakagami, K., Okuyama, S., et al. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2003.10.009 · Cited by 254 · see citing works

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

Nitsch, R. M., Farber, S. A., Growdon, J. H., & Wurtman, R. J. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.11.5191 · Cited by 244 · see citing works

Metabotropic Glutamate Receptor-Mediated Long-Term Depression: Molecular Mechanisms

Gladding, C. M., Fitzjohn, S. M., & Molnár, E. (2009) · Pharmacological Reviews · doi:10.1124/pr.109.001735 · Cited by 233 · see citing works

Kainate Receptor-Mediated Responses in the CA1 Field of Wild-Type and GluR6-Deficient Mice

Bureau, I., Bischoff, S., Heinemann, S. F., & Mulle, C. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-02-00653.1999 · Cited by 215 · see citing works

Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion

Masugi, M., Yokoi, M., Shigemoto, R., Muguruma, K., Watanabe, Y., Sansig, G., van der Putten, H., & Nakanishi, S. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-03-00955.1999 · Cited by 211 · see citing works

Circulating metabolites and general cognitive ability and dementia: evidence from 11 cohort studies

van der Lee, S. J., Teunissen, C. E., Pool, R., Shipley, M. J., Teumer, A., Chouraki, V., Melo van Lent, D., Tynkkynen, J., Fischer, K., Hernesniemi, J., et al. (2018) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2017.11.012 · Cited by 197 · see citing works

Oxidative Nerve Cell Death in Alzheimers Disease and Stroke: Antioxidants as Neuroprotective Compounds

Behl, C., & Moosmann, B. (2002) · Biological Chemistry · doi:10.1515/bc.2002.053 · Cited by 203 · see citing works

Inducible and Reversible NR1 Knockout Reveals Crucial Role of the NMDA Receptor in Preserving Remote Memories in the Brain

Cui, Z., Wang, H., Tan, Y., Zaia, K. A., Zhang, S., & Tsien, J. Z. (2004) · Neuron · doi:10.1016/s0896-6273(04)00072-8 · Cited by 172 · see citing works

Distribution and synaptic localization of immunocytochemically identified NMDA receptor subunit proteins in sensory-motor and visual cortices of monkey and human

Huntley, G., Vickers, J., Janssen, W., Brose, N., Heinemann, S., & Morrison, J. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-06-03603.1994 · Cited by 161 · see citing works

Enhanced cocaine responsiveness and impaired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice

Morishima, Y., Miyakawa, T., Furuyashiki, T., Tanaka, Y., Mizuma, H., & Nakanishi, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500914102 · Cited by 148 · see citing works

Targeting glutamate uptake to treat alcohol use disorders

Rao, P. S. S., Bell, R. L., Engleman, E. A., & Sari, Y. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00144 · Cited by 136 · see citing works

Gut microbiota of mice putatively modifies amino acid metabolism in the host brain

Kawase, T., Nagasawa, M., Ikeda, H., Yasuo, S., Koga, Y., & Furuse, M. (2017) · British Journal of Nutrition · doi:10.1017/s0007114517000678 · Cited by 119 · see citing works

Novel glutamatergic agents for major depressive disorder and bipolar disorder

Machado-Vieira, R., Ibrahim, L., Henter, I. D., & Zarate, C. A. (2012) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.09.010 · Cited by 92 · see citing works

Growth hormone replacement in hypophysectomized rats affects spatial performance and hippocampal levels of NMDA receptor subunit and PSD-95 gene transcript levels

Le Grevès, M., Zhou, Q., Berg, M., Le Grevès, P., Fhölenhag, K., Meyerson, B., & Nyberg, F. (2006) · Experimental Brain Research · doi:10.1007/s00221-006-0438-2 · Cited by 92 · see citing works

Role of glutamate receptors and glial cells in the pathophysiology of treatment-resistant depression

Kim, Y.-K., & Na, K.-S. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.03.009 · Cited by 84 · see citing works

Defined criteria for auxiliary subunits of glutamate receptors

Yan, D., & Tomita, S. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2011.213868 · Cited by 79 · see citing works

Neurophysiological mechanisms of electroconvulsive therapy for depression

Kato, N. (2009) · Neuroscience Research · doi:10.1016/j.neures.2009.01.014 · Cited by 65 · see citing works

<i>N</i>-Methyl-<scp>d</scp>-Aspartate Receptor Subunit Expression in GnRH Neurons Changes during Reproductive Senescence in the Female Rat

Miller, B. H., & Gore, A. C. (2002) · Endocrinology · doi:10.1210/en.2002-220346 · Cited by 59 · see citing works

Moringa oleifera Seed Extract Alleviates Scopolamine-Induced Learning and Memory Impairment in Mice

Zhou, J., Yang, W.-S., Suo, D.-Q., Li, Y., Peng, L., Xu, L.-X., Zeng, K.-Y., Ren, T., Wang, Y., Zhou, Y., et al. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00389 · Cited by 53 · see citing works

Attention deficit induced by blockade of N-methyl d-aspartate receptors in the prefrontal cortex is associated with enhanced glutamate release and cAMP response element binding protein phosphorylation: role of metabotropic glutamate receptors 2/3

Pozzi, L., Baviera, M., Sacchetti, G., Calcagno, E., Balducci, C., Invernizzi, R. W., & Carli, M. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2010.11.060 · Cited by 49 · see citing works

Quantitative localization of NMDAR1 receptor subunit immunoreactivity in inferotemporal and prefrontal association cortices of monkey and human

Huntley, G. W., Vickers, J. C., & Morrison, J. H. (1997) · Brain Research · doi:10.1016/s0006-8993(96)00847-5 · Cited by 47 · see citing works

Expression of ionotropic glutamate receptor subunit mRNAs by paraventricular corticotropin-releasing factor (CRF) neurons

Aubry, J.-M., Bartanusz, V., Pagliusi, S., Schulz, P., & Kiss, J. Z. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12380-6 · Cited by 42 · see citing works

GluN2B-Containing NMDA Receptors Promote Glutamate Synapse Development in Hippocampal Interneurons

Kelsch, W., Li, Z., Wieland, S., Senkov, O., Herb, A., Göngrich, C., & Monyer, H. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1210-14.2014 · Cited by 37 · see citing works

Specificity protein 4 functionally regulates the transcription of NMDA receptor subunits GluN1, GluN2A, and GluN2B

Priya, A., Johar, K., & Wong-Riley, M. T. T. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2013.07.002 · Cited by 33 · see citing works

Evaluation of the Safety, Tolerability, and Pharmacokinetic Profiles of TP0473292 (TS-161), A Prodrug of a Novel Orthosteric mGlu2/3 Receptor Antagonist TP0178894, in Healthy Subjects and Its Antidepressant-Like Effects in Rodents

Watanabe, M., Marcy, B., Hiroki, A., Watase, H., Kinoshita, K., Iijima, M., Marumo, T., Zarate, C. A., & Chaki, S. (2022) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyab062 · Cited by 22 · see citing works

Effects of LY354740, a novel glutamatergic metabotropic agonist, on nonhuman primate hypothalamic–pituitary–adrenal axis and noradrenergic function

Coplan, J. D., Mathew, S. J., Smith, E. L. P., Trost, R. C., Scharf, B. A., Martinez, J., Gorman, J. M., Monn, J. A., Schoepp, D. D., & Rosenblum, L. A. (2001) · CNS Spectrums · doi:10.1017/s1092852900002157 · Cited by 18 · see citing works