The DOI matches its Crossref record; 53 of the 54 references it cites were found in a registry or an index.
alx , a Zebrafish Homolog of Chx10 , Marks Ipsilateral Descending Excitatory Interneurons That Participate in the Regulation of Spinal Locomotor Circuits
Open accessAbstract
Recent molecular genetic studies suggest that the expression of transcription factors in the developing spinal cord helps determine the morphological and physiological properties of neurons. Using the zebrafish preparation, we have examined the properties of neurons marked by alx , a zebrafish homolog of mammalian Chx10 . We performed morphological and physiological studies using transgenic zebrafish expressing fluorescent reporter constructs in cells that had at any time point expressed alx ( alx neurons). Our data reveal that zebrafish alx neurons are all ipsilateral descending neurons that are positive for vesicular glutamate transporter 2, suggesting that they are glutamatergic excitatory interneurons. Patch recordings show that earlier-born neurons are active during stronger movements such as escapes and fast swimming (strong movement class), whereas later-born ones are involved in sustained weak swimming (weak movement class). Paired recordings between alx neurons and motoneurons show that neurons of the strong movement class make frequent monosynaptic excitatory connections onto motoneurons. Thus, neurons of this class are likely premotor interneurons that regulate motoneuron activity during escapes and fast swimming. We also show the existence of a monosynaptic connection between an alx neuron of the weak movement class and a motoneuron. Collectively, our data demonstrate that alx marks ipsilateral descending neurons that are involved in the regulation of motoneuron activity during forms of locomotion, such as escape and swimming.
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“In R7/R8, the former were found to have somata primarily within a medial glutamatergic parasagittal stripe associated with the Alx transcription factor and the latter with a more lateral GABAergic parasagittal stripe associated with the Abx1b transcription factor21,95,96.”
From Predicting modular functions and neural coding of behavior from a synaptic wiring diagram (2024) · cites this paper as [95]
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BackgroundDeletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting
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“To generate alx reporter constructs, we followed the method by Lee et al. (2001), which uses BAC homologous recombination system (a gift from N. Copeland, National Cancer Institute, Frederick, MD).”
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Items 201–299 of 299
Primary cell culture of adult zebrafish spinal neurons for electrophysiological studies
Meade, M. E., Roginsky, J., & Schulz, J. R. (2019) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2019.04.011 · Cited by 10
“…cell selective expression include GFP expression as a reporter of olig2 (Shin et al., 2003), which labels oligodendrocytes and spinal neurons, alx (Kimura et al., 2006), a homolog of chx10, which labels excitatory interneurons in the spinal cord, and even neurons with expression of specific…”
BackgroundArginine vasotocin neuronal development and its projection in the adult brain of the medaka
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The Brain and Spinal Cord Networks Controlling Locomotion
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“In the Ciona MG connectome, three pairs of descending interneurons are predicted to play an important role in both the rhythmicity of swimming movements and their modulation by inputs from the sensory vesicle (Kourakis et al., 2019; Ryan et al., 2016).”
BackgroundZebrafish pigment cells develop directly from persistent highly multipotent progenitorsPreprint
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MethodTaniguchi, A., Kimura, Y., Mori, I., Nonaka, S., & Higashijima, S. (2017) · Development Growth & Differentiation · doi:10.1111/dgd.12412 · Cited by 8
“Tg[HuC: Gal4-VP16] (Kimura et al. 2008), Tg[chx10:Gal4] (Kimura et al. 2013), Tg[eng1b-hs:Gal4] (Kimura et al. 2014), and Tg[vachta-hs:Gal4] (generated in this study) were used as driver strains to express Dendra2 in distinct classes of (or all of) neurons.”
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BackgroundSelf-citationYuan, X., Qin, Y., Wang, J., & Fan, C. (2021) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2021.109053 · Cited by 8
Saltiel, P., d’Avella, A., Tresch, M. C., Wyler, K., & Bizzi, E. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00098 · Cited by 8
“The combination of descending excitation, as discussed above (see also Cowley et al., 2010), and ascending inhibition, would be expected to favor a rostrocaudally traveling wave, as pointed out by Kimura et al. (2006).”
BackgroundHmx3a Has Essential Functions in Zebrafish Spinal Cord, Ear and Lateral Line Development
England, S. J., Cerda, G. A., Kowalchuk, A. M., Sorice, T., Grieb, G., & Lewis, K. E. (2020) · Genetics · doi:10.1534/genetics.120.303748 · Cited by 8
Separate brainstem circuits for fast steering and slow exploratory turns
Xu, L., Zhu, B., Zhu, Z., Tao, X., Zhang, T., Manira, A. E., & Song, J. (2025) · Nature Communications · doi:10.1038/s41467-025-58621-9 · Cited by 6
“We per-formedretrogradelabelingofbrainstemneuronsinthetransgenicline Tg( chx10 :GFP) 27 and Tg( glyt2:GFP ) 28 .”
The biological role of the glycinergic synapse in early zebrafish motility
Hirata, H., Takahashi, M., Yamada, K., & Ogino, K. (2011) · Neuroscience Research · doi:10.1016/j.neures.2011.06.003 · Cited by 7
Juárez‐Morales, J. L., Luna, R. I. M., Zuber, M. E., Roberts, A., & Lewis, K. E. (2017) · Developmental Neurobiology · doi:10.1002/dneu.22490 · Cited by 7
“However, while it is possible to make electrophysiological recordings in zebrafish embryos (e.g., Higashijima et al., 2004; Kimura et al., 2006; Satou et al., 2009; Bohm et al., 2016) their small size and fragility makes these techniques very technically challenging, compared to X.”
BackgroundResultInfluentialRulands, S., González, A. B. I., & Boije, H. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14257 · Cited by 7
Characterization of Transgenic Lines Labeling Reticulospinal Neurons in Larval Zebrafish
Collins, E. M., Silva, P. T., Ostrovsky, A. D., Renninger, S. L., Tomás, A. R., del Corral, R. D., & Orger, M. B. (2025) · eNeuro · doi:10.1523/eneuro.0581-24.2025 · Cited by 8
“It labels medial IL projecting cells in the hindbrain and spinal cord, shown to be glutamatergic descending interneurons providing excitatory drive to motoneurons in the spinal cord (Kimura et al., 2006).”
Electrical Coupling in the Generation of Vertebrate Motor Rhythms
Li, W., & Rekling, J. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-803471-2.00011-4 · Cited by 6
Evolution of lbx spinal cord expression and function
Juárez‐Morales, J. L., Weierud, F. K., England, S. J., Demby, C., Santos, N., Grieb, G., Mazan, S., & Lewis, K. E. (2021) · Evolution & Development · doi:10.1111/ede.12387 · Cited by 5
“…phenotypes, we used slc32a1 (formerly called viaat), which encodes a vesicular inhibitory amino acid transporter and labels all inhibitory cells (Kimura et al., 2006), a mixture of two probes (glyt2a and glyt2b) for slc6a5 (previously called glyt2), which encodes a glycine transporter necessary…”
MethodOrts-Del’Immagine, A., Dhanasekar, M., Lejeune, F., Roussel, J., & Wyart, C. (2021) · Glia · doi:10.1002/glia.24118 · Cited by 8
“Mauthner neurons received direct and massive input from primary acoustic afferents from the ear and send monosynaptic contacts onto spinal neurons, such as glutamatergic excitatory premotor interneurons (V2a neurons) and motoneurons (Fetcho, 1991; Fetcho & Faber, 1988; Kimura et al., 2006).”
BackgroundAlunni, A., Coolen, M., Foucher, I., & Bally‐Cuif, L. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-814405-3.00026-6 · Cited by 6
Kawamura, A., Ovara, H., Ooka, Y., Kinoshita, H., Hoshikawa, M., Nakajo, K., Yokota, D., Fujino, Y., Higashijima, S., Takada, S., et al. (2015) · Developmental Biology · doi:10.1016/j.ydbio.2015.11.010 · Cited by 6
“To generate the BAC EGFP reporter, a DNA fragment that contained EGFP, 3′UTR and the polyadenylation signal from bovine growth hormone, and a kanamycin resistance gene was amplified by PCR as described previously (Kimura et al., 2006).”
MethodSelf-citationCell-type-specific origins of locomotor rhythmicity at different speeds in larval zebrafish
Agha, M. A., Kishore, S., & McLean, D. L. (2024) · eLife · doi:10.7554/elife.94349.3 · Cited by 5
Montgomery, J. E., Wahlstrom‐Helgren, S., Vanpelt, K. T., & Masino, M. A. (2021) · Physiological Reports · doi:10.14814/phy2.14774 · Cited by 5
“V2a interneurons directly synapse onto motor neurons (Kimura et al. 2006; Svara et al. 2018), providing excitatory drive and regulating locomotor frequency (Ampatzis et al. 2014; Eklöf- Ljunggren et al. 2012; McLean et al. 2008).”
BackgroundRedefining the central pattern generator for vertebrate locomotion
Manira, A. E. (2026) · Nature reviews. Neuroscience · doi:10.1038/s41583-026-01029-1 · Cited by 7
Thirumalai, V., & Jha, U. (2022) · Advances in neurobiology · doi:10.1007/978-3-031-07167-6_8 · Cited by 3
Inhibitory control explains locomotor statistics in walking Drosophila
Gattuso, H. C., van Hassel, K. A., Freed, J. D., Nuñez, K. M., de la Rea, B., May, C. E., Ermentrout, B., Victor, J. D., & Nagel, K. I. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2407626122 · Cited by 7
“Similarly, in both mice and zebrafish, a homologous set of retic-ulospinal neurons labeled by chx10 drive turning through ipsilateral modulation of oscillatory spinal circuits ( 61 – 64 ).”
Cell-type-specific origins of locomotor rhythmicity at different speeds in larval zebrafish
Agha, M. A., Kishore, S., & McLean, D. L. (2024) · eLife · doi:10.7554/elife.94349 · Cited by 12
Optical highlighter molecules in neurobiology
Datta, S. R., & Patterson, G. H. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.11.007 · Cited by 4
“Since this initial demonstration, a number of different highlighters have been successfully deployed in the chick [52–57], zebrafish [58,59,60 ,61 ,62], xenopus [63], ciona intestinalis [64 ] and in mammals [52,54,57,61 ,63,65,66] to track the fates of neural precursors during development.”
Neural Patterning and CNS Functions of Wnt in Zebrafish
Dorsky, R. I. (2008) · Methods in molecular biology · doi:10.1007/978-1-60327-469-2_20 · Cited by 4
V2b neurons act via multiple targets in spinal motor networksPreprint
Sengupta, M., & Bagnall, M. W. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.01.502410 · Cited by 5
Inhibitory control of locomotor statistics in walking DrosophilaPreprint
Gattuso, H. C., van Hassel, K. A., Freed, J. D., Nuñez, K. M., de la Rea, B., May, C. E., Ermentrout, B., Victor, J. D., & Nagel, K. I. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.15.589655 · Cited by 4
“Similarly, in both mice and zebrafish, a homologous set of reticulospinal neurons labelled by chx10 drive turning through ipsilateral modulation of oscillatory spinal circuits (Cregg et al 2018, Orger et al 2008, Huang et al 2013, Kimura et al 2006).”
Regeneration after Spinal Cord Injury: A Review on the Crucial Aspects of V2a Interneurons
Khavandegar, A., Bolstad, L. J., Hanna, A. S., & Hellenbrand, D. J. (2025) · Journal of Neurotrauma · doi:10.1177/08977151251386031 · Cited by 4
“52 Some V2a interneurons regulate timing by synapsing with other V2a and V0d interneurons, while others control amplitude by synapsing with local motor neurons.”
Cucun, G., Köhler, M., Pfitsch, S., & Rastegar, S. (2023) · FEBS Journal · doi:10.1111/febs.16913 · Cited by 4
“5) [14,19,80].”
England, S. J., Rusnock, A. K., Mujcic, A., Kowalchuk, A. M., de Jager, S., Hilinski, W. C., Juárez‐Morales, J. L., Smith, M. E., Grieb, G., Banerjee, S., et al. (2023) · Neural Development · doi:10.1186/s13064-023-00176-w · Cited by 3
“1 (expressed by KA and V2b cells [37, 72, 74, 75]), en1b (expressed by V1 cells [6, 71]), dmrt3a (expressed by dI6 cells [56, 76, 77]), lbx1a (expressed by dI4 and dI6 cells, [4, 7, 78– 81]) (Fig.”
BackgroundV2b Neurons Act via Multiple Targets to Produce in Phase Inhibition during Locomotion
Sengupta, M., Bertram, A., Zhu, S., Goodhill, G. J., & Bagnall, M. W. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.1530-24.2025 · Cited by 4
Wyart, C., & Knafo, S. (2015) · Biological and medical physics, biomedical engineering · doi:10.1007/978-3-319-12913-6_8 · Cited by 4
“homologs of the mouse V2a interneurons [5, 13, 106, 107] (see Sect.”
BackgroundOptogenetics: Illuminating Sources of Locomotor Drive
McLean, D. L. (2013) · Current Biology · doi:10.1016/j.cub.2013.04.015 · Cited by 3
Locomotion: Electrical Coupling of Motor and Premotor Neurons
Prendergast, A. E., & Wyart, C. (2016) · Current Biology · doi:10.1016/j.cub.2016.02.021 · Cited by 3
“Some V2as and Motor Neurons Are Electrically Coupled beyond Early Development Other groups [4,10] had previously reported electrical coupling between”
BackgroundYan, Q., Zhai, L., Zhang, B., & Dallman, J. E. (2016) · The Journal of Comparative Neurology · doi:10.1002/cne.24152 · Cited by 3
“Conversely, glutamatergic Circumferential Descending interneurons contact motor neurons in the lateral neuropil on distal dendrites (Kimura et al., 2006) where they provide critical excitatory drive to initiate locomotory behaviors (Ausborn, Mahmood, & El Manira, 2012; Eklof-Ljunggren et al., 2012;…”
BackgroundDistinct Spinal V2a and V0d Microcircuits Distribute Locomotor Control in Larval ZebrafishPreprint
Menelaou, E., Kishore, S., & McLean, D. L. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/559799 · Cited by 2
“Although past studies have also revealed V2a neurons that use either electric, glutamatergic or mixed synaptic connections (Bhatt et al., 2007; Kimura et al., 2006; Song et al., 2016; Song et al., 2018), our findings additionally suggest that individual V2a neurons of either type can form one or…”
BackgroundMethodResultInfluentialLowe, E. K., Racioppi, C., Peyriéras, N., Ristoratore, F., Christiaen, L., Swalla, B. J., & Stolfi, A. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/567719 · Cited by 3
“In Ciona and M. occidentalis, they are marked by expression of Vsx (Imai et al., 2009; Stolfi and Levine, 2011), the ortholog of conserved spinal cord interneuron regulator Vsx2/Chx10 (Altun-Gultekin et al., 2001; Kimura et al., 2006; Liu et al., 1994).”
BackgroundMatrix topology guides collective cell migration in vivoPreprint
Soans, K. G., Ramos, A. P., Sidhaye, J., Krishna, A., Solomatina, A., Hoffmann, K. B., Schlüßler, R., Guck, J. R., Sbalzarini, I. F., Modes, C. D., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.31.478442 · Cited by 3
The Tabulae Paralytica: Multimodal single-cell and spatial atlases of spinal cord injuryPreprint
Skinnider, M. A., Gautier, M., Teo, A. Y. Y., Kathe, C., Hutson, T. H., Laskaratos, A., de Coucy, A., Regazzi, N., Aureli, V., James, N. D., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.06.23.544348 · Cited by 3
The neuronal architecture of autonomic dysreflexiaPreprint
Soriano, J. E., Hudelle, R., Mahe, L., Gautier, M., Teo, A. Y. Y., Skinnider, M. A., Laskaratos, A., Ceto, S., Kathe, C., Hutson, T. H., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.06.592781 · Cited by 4
Shimizu, S., Katayama, T., Nishiumi, N., Tanimoto, M., Kimura, Y., & Higashijima, S. (2025) · Zoological Letters · doi:10.1186/s40851-024-00247-8 · Cited by 2
Self-citationRerkamnuaychoke, W., Sreevidya, V. S., & Svoboda, K. R. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.117993 · Cited by 2
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“The topographic recruitment of neurons during larval zebrafish swimming was later shown to represent both an order of movement speed/strength and the temporal emergence of network components (Kimura et al., 2006; McLean and Fetcho, 2009).”
BackgroundToward a comprehensive model of circuits underlying locomotion: What did we learn from zebrafish?
Dumitrescu, A. S., Fidelin, K., & Wyart, C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816477-8.00006-5 · Cited by 1
Currie, S. P. (2014) · St Andrews Research Repository (St Andrews Research Repository) · Cited by 2
Single cell RNA-seq analysis of spinal locomotor circuitry in larval zebrafishPreprint
Kelly, J. J., Wen, H., & Brehm, P. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.06.06.543939 · Cited by 2
Whole-brain mapping of spinal-projecting neurons in larval zebrafishPreprint
Tano, M. C., Fidelin, K., Welch, T., Narayan, S., Ahrens, M. B., Dubuc, R., & Wyart, C. (2026) · eLife · doi:10.7554/elife.112062 · Cited by 2
Faini, G., Tuffery, M., Saleem, A., Zhang, L., Du, F., Bourdellès, G. L., Duroure, K., Schreiter, E. R., Tanese, D., Emiliani, V., et al. (2026) · Nature Neuroscience · doi:10.1038/s41593-026-02423-9 · Cited by 1
“…accessible models such as zebrafish, expresses a photoconvertible fluorescent protein in differentiating neurons, distinguishing neurons born after photoconversion 21,22 ; although applicable broadly across a genetically defined population, it cannot resolve neurons born within a defined period.”
V1-Derived Renshaw Cells and IA Inhibitory Interneurons Differentiate Early During Development
González, A. B. (2011) · OhioLink ETD Center (Ohio Library and Information Network) · Cited by 1
Dudczig, S., Currie, P. D., Poggi, L., & Jusuf, P. R. (2017) · Journal of Visualized Experiments · doi:10.3791/55490 · Cited by 1
Martin, T. C., & Ribera, A. B. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-397266-8.00006-5 · Cited by 2
Locomotor control: Inhibiting actions locally and senses globally
Jay, M., & McLean, D. L. (2021) · Current Biology · doi:10.1016/j.cub.2021.07.050 · Cited by 1
Growing Importance of Zebrafish in Translational Neuroscience
Rajanikant, G. K., & Kalthur, G. (2022) · Springer eBooks · doi:10.1007/978-981-16-5217-2_16 · Cited by 1
Wiggin, T. D. (2015) · University of Minnesota Digital Conservancy (University of Minnesota) · Cited by 1
Cell-type-specific origins of locomotor rhythmicity at different speeds in larval zebrafishPreprint
Agha, M. A., Kishore, S., & McLean, D. L. (2024) · eLife · doi:10.7554/elife.94349.2 · Cited by 2
Excitatory neurons as the default fate in bifurcation of excitatory and inhibitory neuron lineagesPreprint
wang, M., Qiu, X.-Y., Duan, Y.-B., Tang, X., Lu, Q., Li, Y., Qin, H., Long, X.-T., Jin, M., Fan, P.-Y., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.10.29.685327 · Cited by 1
Computational modeling of speed microcircuits in larval zebrafish spinal cord with Sili Fish
Topcu, E., & Bui, T. V. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00393.2024
Ljunggren, E. E. (2012) · Figshare
EPHA4 and V2 interneurons in the mammalian locomotor network
Lundfald, L. (2008) · Figshare
Organization and connectivity of premotor interneurons in the mouse spinal cord
Stepien, A. E. (2011) · edoc (University of Basel) · doi:10.5451/unibas-005712076
A Topographic Map Of Function Along The Axis Of Stripes In The Hindbrain Of Behaving Zebrafish
Riley, M. R. (2010) · eCommons (Cornell University)
The Development And Organization Of Dendrites Of Motoneurons In Larval Zebrafish
Kishore, S. (2011) · eCommons (Cornell University)
Functional Analysis of Spinal Commissural Neurons in Zebrafish
Satou, C. (2010) · SOKENDAI (Graduate University for Advanced Studies)
Locomotor pattern generation in the spinal cord: Studies in adult lamprey and zebrafish
Mahmood, R. Z. (2011) · Figshare
Editorial for Molecular and Cell Science JFB
Maclean, N. (2008) · Journal of Fish Biology · doi:10.1111/j.1095-8649.2008.02027.x
Motor control in zebrafish : excitatory drive and developmental changes
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Functional organization of segmentally homologous neurons in hindbrain
根木, 大., & Neki, D. (2014) · Nagoya University Repository (NAGOYA Repository)
Sensorimotor integration in the moving spinal cord
Knafo, S. (2015) · theses.fr (ABES) · doi:10.70675/80d97ac7z5404z4577za1d5z1c8381c5051c
“Of interest is the fact that CiDs interneurons are the fish homologs of the mouse V2a interneurons (Kimura, 2006; Kimura et al., 2013) (see section 2.”
InfluentialImaging the Nervous System: Insights Into Central and Peripheral Glia Development
Kucenas, S., & Appel, B. (2010) · WORLD SCIENTIFIC eBooks · doi:10.1142/9789814307352_0002
Département de Pathologie et Biologie Cellulaire
de Médecine, F. (2010)
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Modulation of Cholinergic Signaling in Embryonic Zebrafish: Anatomical and Behavioral Consequences
Menelaou, E. (2010) · Louisiana State University · doi:10.31390/gradschool_dissertations.3584
“…and axon size, axonal trajectory, dendritic morphology, extend of axonal projections and timing of axogenesis) (Bernhardt et al., 1990; Hale et al., 2001), transmitter phenotypes (Higashijima et al., 2004a), and molecular profiles (Appel et al., 1995; Higashijima et al., 2004b; Kimura et al, 2006).”
BackgroundThe neural circuits moving fly larvae
Kohsaka, H. (2018) · Hikaku seiri seikagaku(Comparative Physiology and Biochemistry) · doi:10.3330/hikakuseiriseika.35.93
LOCOMOTION CHARACTERIZATION OF DCC AND NCK2 MUTANT MICE
Li, Q. (2019) · DalSpace (Dalhousie University)
Recent Papers on Zebrafish and Other Aquarium Fish Models
(2006) · Zebrafish · doi:10.1089/zeb.2006.3.387
Spinal interneurons and cellular engineering
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Single cell RNA-seq analysis of spinal locomotor circuitry in larval zebrafishPreprint
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Self-citationSingle cell RNA-seq analysis of spinal locomotor circuitry in larval zebrafishPreprint
Kelly, J. J., Wen, H., & Brehm, P. (2023) · eLife · doi:10.7554/elife.89338.2
Cell-type-specific origins of locomotor rhythmicity at different speeds in larval zebrafishPreprint
Agha, M. A., Kishore, S., & McLean, D. L. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.11.575271
Cell-type-specific origins of spinal rhythmicity at different locomotor speeds in larval zebrafishPreprint
Agha, M. A., Kishore, S., & McLean, D. L. (2024) · eLife · doi:10.7554/elife.94349.1
Noradrenaline prolongs the state of motor arrest via cerebrospinal fluid signalingPreprint
Dhanasekar, M., Fidelin, K., Greco, M., Lunsford, E. T., Tano, M. C., Deleuze, C., Moisan, L., Mora, T., Walczak, A. M., & Wyart, C. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.06.704024
Boulanger-Weill, J. (2015) · theses.fr (ABES) · doi:10.70675/2e2345c3z54b6z40bbzbb39z21007cd16800
“These lines were generated using the BAC (bacterial artificial chromosome) homologous recombination technique with either the I-Sce I-mediated method (Kimura et al., 2006) or the Tol2-mediated method (Suster et al.”
Neuronal populations underlying locomotion in zebrafish
Sternberg, J. R. (2016) · theses.fr (ABES) · doi:10.70675/4672b940zaeefz4dc4zadc5z91d95b993c6f
Investigation of neuropeptides in spinal circuits with special emphasis on somatostatin
Quan, F. B. (2020) · theses.fr (ABES) · doi:10.70675/bf43ed2azb519z404ez9000z923c31db3a40
The neuronal basis of auditory-induced and spontaneous behavior in the zebrafish larva
Privat, M. (2021) · theses.fr (ABES) · doi:10.70675/c7cf74ebze0c8z47f3zb7daz88662078804c
The glial action potential and its role during the emergence of motor behaviour
Lafont, A. (2023) · theses.fr (ABES) · doi:10.70675/ac5f5419z414cz42cbz80d0z6f3e3d39cca8
Organization and locomotor functions of V2a-derived reticulospinal neurons in zebrafish
Jia, X. (2025) · theses.fr (ABES) · doi:10.70675/c5ad2c47z099az419fz8333z67b01a7bbb08
Fioritti, N., Shaikh, M., Cazzagon, G., Powell, G. T., Turner, K., tucker, L., Mallucci, A., Hadjieconomou, E., Carter, S. P., Wehner, D., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.11.737910
“…mw60 (Miesfeld and Link, 2014); Tg(β-actin:HRAS-RFP) vu119 (Cooper et al., 2005); yap1 nl13 (J. B. Miesfeld et al., 2015); Tg(vsx2:GFP) nns1 (Kimura et al., 2006); lrp5 ulm21 (this study); lrp6 u348 (Powell et al., 2024); fz5 sgu1 (Monfries et al., 2025); apc CA50a ( Paridaen et al., 2009);…”
Whole brain mapping of spinal-projecting neurons in larval zebrafishPreprint
Tano, M. C., Fidelin, K., Welch, T., Narayan, S., Ahrens, M. B., Dubuc, R., & Wyart, C. (2026) · eLife · doi:10.7554/elife.112062.2
Metadata
- Authors
- Kimura, Y., Okamura, Y., & Higashijima, S.-I.
- Affiliations
- National Institutes of Natural Sciences (JP)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2006-05-24
- Volume
- 26
- Issue
- 21
- Pages
- 5684-5697
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- PMC
- PMC6675258
- OpenAlex
- W2030150624
- Cited by
- 302
- References
- 54
- Citations by year
- 2026: 6 · 2025: 10 · 2024: 9 · 2023: 17 · 2022: 16 · 2021: 18 · 2020: 15 · 2019: 18 · 2018: 11 · 2017: 12 · 2016: 17 · 2015: 13 · 2014: 19 · 2013: 13 · 2012: 13
- FWCI
- 6.77
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Zebrafish Biomedical Research Applications
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- spinal interneurons, vesicular glutamate transporter 2, spinal locomotor circuits, premotor interneurons, swimming behavior, escape behavior, zebrafish
- MeSH terms
- Animals, Efferent Pathways, Eye Proteins, Feedback, Interneurons, Locomotion, Nerve Net, Spinal Cord, Tissue Distribution, Zebrafish, Homeodomain Proteins, Excitatory Postsynaptic Potentials, Zebrafish Proteins
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