Antibiotic resistance and persistence—Implications for human health and treatment perspectives

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Molecular mechanisms of antibiotic resistance

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Bacterial Persistence as a Phenotypic Switch

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Molecular Insights Into the Role of Gut Microbiota in Antibiotic Therapy Selection and Resistance Mitigation

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Understanding antibiotic knowledge, attitudes, and practices: a cross-sectional study in physicians from a Colombian region, 2023

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Synthesis of Sm-Doped CuO–SnO2:FSprayed Thin Film: An Eco-Friendly Dual-Function Solution for the Buffer Layer and an Effective Photocatalyst for Ampicillin Degradation

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Molecular Monitoring of Fungicide Resistance in Crop Phytopathogens

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Emergence and spread of multidrug-resistant pathogens: A global health challenge

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Mechanism of Enrofloxacin-Induced Multidrug Resistance in the Pathogenic Vibrio Harveyi from Diseased Abalones

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Application of CRISPR/Cas9-based genome editing in ecotoxicology

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Cerium Dioxide–Dextran Nanocomposites in the Development of a Medical Product for Wound Healing: Physical, Chemical and Biomedical Characteristics

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Unraveling persistent bacteria: Formation, niches, and eradication strategies

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Multiresistant Enterobacteriaceae in yellow‐legged gull chicks in their first weeks of life

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Impact of the COVID-19 pandemic on Haemophilus influenzae infections in pediatric patients hospitalized with community acquired pneumonia

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Introducing First-Year Undergraduate Students the Fundamentals of Antibiotic Sensitivity Testing through a Combined Computer Simulation and Face-to-Face Laboratory Session

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Nanotechnology in Gene Editing: Pioneering CRISPR‐Cas Delivery Systems to Tackle Antibiotic Resistance

Gholamian, S., Baghaee, P., & Doroudian, M. (2025) · Advanced Therapeutics · doi:10.1002/adtp.202400412 · Cited by 15

Unveiling the Mechanisms of Bacterial Resistance and Countermeasures

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Bionic Janus hydrogel drives infected Achilles tendon regeneration via mechano-immune spatiotemporal steering

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Contribution of efflux and mutations in fluoroquinolone susceptibility in MDR enterobacterial isolates: a quantitative and molecular study

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Trends and seasonal variation of antibiotic consumption by community residents in Hefei, China, 2012–2016

He, J., You, E., Zhong, Q., & Huang, F. (2023) · Public Health · doi:10.1016/j.puhe.2023.04.011 · Cited by 11

Effects of different addition levels of CHM-JM113 on growth performance, antioxidant capacity, organ index, and intestinal health of AA broilers

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α-Ketoglutarate downregulates thiosulphate metabolism to enhance antibiotic killing

Peng, L.-T., Tian, S.-Q., Guo, W.-X., Chen, X.-W., Wu, J.-H., Liu, Y.-L., & Peng, B. (2024) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2024.107214 · Cited by 11

Antimicrobial resistance at the human–animal–environment interface: A focus on antimicrobial-resistant Escherichia coli transmission dynamics, clinical implications, and future directions

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Convergence of mcr-1 and broad-spectrum β-lactamase genes in Escherichia coli strains from the environmental sector

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Effects of Lagenaria siceraria (Molina) Standl polysaccharides on growth performance, immune function, cecum microorganisms and short-chain fatty acids in broilers

Zhang, Z., Dong, S., Li, J., Aizezi, M., Huang, P., Abula, S., Mai, Z., Liu, D., & Wusiman, A. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1428623 · Cited by 11

Drug Repurposing: Research Progress of Niclosamide and Its Derivatives on Antibacterial Activity

Liu, Z., Liang, X., Zhang, Y., Deng, W., Wang, Y., Lu, Z., Liu, Q., & Wei, L. (2024) · Infection and Drug Resistance · doi:10.2147/idr.s490998 · Cited by 11

Antioxidant and Antimicrobial Properties of Probiotics: Insights from In Vitro Assays

Costa, F. F., Dias, T. G., Mendes, P. M., Viana, J. P. M., Madeira, E. B., Pereira, A. L. F., Ferreira, A. G. N., Neto, M. S., Dutra, R. P., Reis, A. S., et al. (2024) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-024-10426-w · Cited by 11

Perspective on Antibiotic Resistance in Bangladesh: A Critical Yet Overlooked Public Health Crisis

Hassan, M. M., & Nohor, N. (2025) · Health Science Reports · doi:10.1002/hsr2.70407 · Cited by 11

Phagetherapy updates: New frontiers against antibiotic resistance

Malik, S., Ahsan, O., Muhammad, K., Munawar, N., & Waheed, Y. (2025) · European Journal of Microbiology and Immunology · doi:10.1556/1886.2024.00126 · Cited by 11

Trehalose catalytic shift inherently enhances phenotypic heterogeneity and multidrug resistance in Mycobacterium tuberculosis

Lee, J. J., Swanson, D. H., Lee, S.-K., Dihardjo, S., Lee, G. Y., Gelle, S., Seong, H. J., Bravo, E. R. M., Taylor, Z. E., VanNieuwenhze, M. S., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-61703-3 · Cited by 12

Bifidobacteria in antibiotic-associated dysbiosis: restoring balance in the gut microbiome

Jena, R., Singh, N. A., Ahmed, N., & Choudhury, P. K. (2025) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-025-04517-1 · Cited by 14

Antimicrobial activity of CT-K3K7, a modified peptide by lysine substitutions from ctry2459 - A Chaerilus tryznai scorpion venom peptide

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Relationships between Efflux Pumps and Emergence of Heteroresistance: A Comprehensive Study on the Current Findings

Abavisani, M., Kodori, M., Akrami, F., Radfar, A., & Hashemi, A. (2022) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2022/3916980 · Cited by 11

Safety evaluations of a synthetic antimicrobial peptide administered intravenously in rats and dogs

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Systemic Effects of a Phage Cocktail on Healthy Weaned Piglets

Liu, Y., Lin, Y., & Zhu, W. (2024) · Biology · doi:10.3390/biology13040271 · Cited by 11

Targeting lon protease to inhibit persister cell formation in Salmonella Typhimurium: a drug repositioning approach

Narimisa, N., Razavi, S., Khoshbayan, A., Gharaghani, S., & Jazi, F. M. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1427312 · Cited by 10

Social and ecological determinants of antimicrobial resistance in Africa: a systematic review of epidemiological evidence

Bennett, C., Russel, W. A., Upton, R. L., Frey, F. M., & Taye, B. (2024) · Antimicrobial Stewardship & Healthcare Epidemiology · doi:10.1017/ash.2024.375 · Cited by 11

In vitro and in vivo activities of scutellarein, a novel polyphosphate kinase 1 inhibitor against Acinetobacter baumannii infection

Song, Y., Lv, H., Xu, L., Liu, Z., Wang, J., Fang, T., Deng, X., Zhou, Y., & Li, D. (2024) · Microbial Cell Factories · doi:10.1186/s12934-024-02540-9 · Cited by 10

Multi-Omics Reveal the Improvements of Nutrient Digestion, Absorption, and Metabolism and Intestinal Function via GABA Supplementation in Weanling Piglets

Zeng, Y., Hu, H., He, Y.-W., Deng, Z., Guo, Y., & Zhou, X.-H. (2024) · Animals · doi:10.3390/ani14223177 · Cited by 10

SAMP: Identifying antimicrobial peptides by an ensemble learning model based on proportionalized split amino acid composition

Feng, J., Sun, M., Liu, C., Zhang, W., Xu, C., Wang, J., Wang, G., & Wan, S. (2024) · Briefings in Functional Genomics · doi:10.1093/bfgp/elae046 · Cited by 11

A multi-functional oxidative konjac glucomannan/ε-poly-l-lysine hydrogel with antibacterial, haemostatic, and chronic diabetic wound-treating properties

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Deep eutectic solvent enhances antibacterial activity of a modular lytic enzyme against Acinetobacter baumannii

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Tea Catechins: Potential Plant-Derived Feed Additives for Improving Chicken Intestinal Health and Productivity

Tian, B., Zhuang, W., Fan, Y., Hu, Y., Cui, X., Li, T., Zhang, L., Luo, X., & Wang, S. (2025) · Animals · doi:10.3390/ani15111553 · Cited by 10

Targeting bacterial persistence with bacteriophages: a next-generation antimicrobial strategy

Kim, S. G. (2025) · Virology · doi:10.1016/j.virol.2025.110649 · Cited by 11

Design, synthesis, and biological assessment of a novel series of coumarin-tethered thiazole derivatives as potential antibacterial agents

Ebaid, M. S., Farag, H., Abdelraof, M., Saleh, A. M., Thabit, M. G., Dziadek, J., Youssef, A. A., & Sabt, A. (2025) · Frontiers in Chemistry · doi:10.3389/fchem.2025.1627186 · Cited by 15

Combating multi-drug resistance with silver nanoparticles: A systematic review

Pachghare, P., Zambre, D., Malode, D., Kale, M. B., Wankhede, N. L., Trivedi, R., Umekar, M. J., & Raut, N. (2025) · The Microbe · doi:10.1016/j.microb.2025.100608 · Cited by 15

Pomegranate Extract Affects Fungal Biofilm Production: Consumption of Phenolic Compounds and Alteration of Fungal Autoinducers Release

Colombari, B., Tagliazucchi, D., Odorici, A., Pericolini, E., Foltran, I., Pinetti, D., Meto, A., Peppoloni, S., & Blasi, E. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192114146 · Cited by 10

Bioinformatics toolbox for exploring target mutation-induced drug resistance

Huang, Y., Sun, P., Chen, Y., Liu, H., Hao, G., & Song, B.-A. (2023) · Briefings in Bioinformatics · doi:10.1093/bib/bbad033 · Cited by 9

Antibiotic therapy in dogs and cats in general practice in the United Kingdom before referral

Bravo, R. E. D. S., Sharman, M. J., Raj, J., & Scudder, C. (2023) · Journal of Small Animal Practice · doi:10.1111/jsap.13615 · Cited by 10

Ethical Considerations in Implementing Doxycycline Postexposure Prophylaxis for the Prevention of Bacterial Sexually Transmitted Infections

Sugarman, J., Taylor, H. A., Bachmann, L. H., Barbee, L. A., Cahill, S., Celum, C., Cohen, S. E., Faden, R., Luetkemeyer, A. F., Mayer, K. H., et al. (2023) · Sexually Transmitted Diseases · doi:10.1097/olq.0000000000001907 · Cited by 10

Antibacterial agents and the fight against antibiotic resistance: A real-world evidence analysis of consumption and spending by an Italian healthcare company

Ferrara, F., Capuozzo, M., Pasquinucci, R., Langella, R., Trama, U., Nava, E., & Zovi, A. (2024) · Annales Pharmaceutiques Françaises · doi:10.1016/j.pharma.2024.01.001 · Cited by 10

Characterization and investigation of cytotoxicity and antimicrobial properties of coencapsulated limonene and thymol into the Ferula assafoetida gum microparticles

Tashakor, A., Rezaei, A., Fouladseresht, H., & Mansury, D. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130338 · Cited by 10

Assessing Antibiotic Tolerance of Staphylococcus aureus Derived Directly from Patients by the Replica Plating Tolerance Isolation System (REPTIS)

Herren, S. C., Huemer, M., Acevedo, C., Andreoni, F., Gómez-Mejía, A., Shambat, S. M., Hasse, B. K., Zbinden, R., Brugger, S. D., & Zinkernagel, A. S. (2021) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00967-21 · Cited by 10

Omadacycline for treatment of acute bacterial infections: a meta-analysis of phase II/III trials

Lin, F., He, R. X., Yu, B., Deng, B., Ling, B., & Yuan, M.-Y. (2023) · BMC Infectious Diseases · doi:10.1186/s12879-023-08212-0 · Cited by 9

Single-cell microfluidics enabled dynamic evaluation of drug combinations on antibiotic resistance bacteria

Li, X., Song, Y., Chen, X., Yin, J., Wang, P., Huang, H., & Yin, H. (2023) · Talanta · doi:10.1016/j.talanta.2023.124814 · Cited by 9

Antibiotic resistance in patients with liver cirrhosis: Prevalence and current approach to tackle

Liakina, V. (2023) · World Journal of Clinical Cases · doi:10.12998/wjcc.v11.i31.7530 · Cited by 8

Polylactic acid electrospun membrane loaded with cerium nitrogen co-doped titanium dioxide for visible light-triggered antibacterial photocatalytic therapy

Lv, H., Xia, X., Sun, S., Niu, Z., Liu, J., & Li, X. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1375956 · Cited by 9

Melatonin Protects Against Colistin‐Induced Intestinal Inflammation and Microbiota Dysbiosis

Jia, Y., Zhang, T., He, M., Yang, B., Wang, Z., & Liu, Y. (2024) · Journal of Pineal Research · doi:10.1111/jpi.12989 · Cited by 9

Biochemistry and Future Perspectives of Antibiotic Resistance: An Eye on Active Natural Products

Caioni, G., Reyes, C. P., Laurenti, D., Chiaradia, C., Dainese, E., Mattioli, R., Risola, D. D., Santavicca, E., & Francioso, A. (2024) · Antibiotics · doi:10.3390/antibiotics13111071 · Cited by 12

Bioassay-Guided Isolation and Identification of Antibacterial Compounds from Invasive Tree of Heaven Stem and Trunk Bark

Cselőtey, A., Baglyas, M., Király, N., Ott, P. G., Glavnik, V., Vovk, I., & Móricz, Á. M. (2024) · Molecules · doi:10.3390/molecules29245846 · Cited by 9

Biosensing for rapid detection of MDR, XDR and PDR bacteria

Rastmanesh, S., Zeinaly, I., Alivirdiloo, V., Mobed, A., & Darvishi, M. (2024) · Clinica Chimica Acta · doi:10.1016/j.cca.2024.120121 · Cited by 11

Isolation, characterization and liposome-loaded encapsulation of a novel virulent Salmonella phage vB-SeS-01

Luo, Y., Mahillon, J., Sun, L., You, Z., & Hu, X. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1494647 · Cited by 9

Metabolic crossroads: unravelling immune cell dynamics in gastrointestinal cancer drug resistance

suri, C., Pande, B., Sahithi, L. S., Swarnkar, S., Khelkar, T., & Verma, H. K. (2025) · Cancer Drug Resistance · doi:10.20517/cdr.2024.164 · Cited by 9

Comprehensive analysis of Enterobacteriaceae IncX plasmids reveals robust conjugation regulators PrfaH, H-NS, and conjugation-fitness tradeoff

Yang, J., Lu, Y., Yu, J., Cai, X., Wang, C., Lv, L., Moran, R. A., Zhao, X., Hu, Z., Deng, M., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-07782-w · Cited by 9

Multifaceted quorum-sensing inhibiting activity of 3-(Benzo[d][1,3]dioxol-4-yl)oxazolidin-2-one mitigates Pseudomonas aeruginosa virulence

Wu, Y., Wen, F., Gou, S., Ran, Q., Chu, Y., Ma, W., & Zhao, K. (2025) · Virulence · doi:10.1080/21505594.2025.2479103 · Cited by 9

Outcome of Bloodstream Infections Caused by Antibiotic-Resistant Bacteria: A 7-Year Retrospective Study at the University Hospital of Palermo, Italy

Pipitò, L., Bono, E., Mazzola, C. V., Rubino, R., Anastasia, A., Distefano, S. A., Firenze, A., Giammanco, A., Bonura, C., & Cascio, A. (2025) · Antibiotics · doi:10.3390/antibiotics14050464 · Cited by 9

Comprehensive wound healing using ETN@Fe7S8 complex by positively regulating multiple programmed phases

Chen, M., Liu, T., Wang, X., Gao, L., Cheng, Y., Jiang, J., & Zhang, J. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03396-w · Cited by 9

Genetic diversity and molecular epidemiology of Streptococcus uberis in high-prevalence mastitis herds

Srithanasuwan, A., Zou, Y., Suriyasathaporn, W., & Schukken, Y. H. (2025) · Journal of Dairy Science · doi:10.3168/jds.2025-26378 · Cited by 9

AI-driven modelling, antimicrobial discovery, and precision therapeutics for targeting bacterial persisters

Yakobi, S. H., & Nwodo, U. U. (2025) · In Silico Research in Biomedicine · doi:10.1016/j.insi.2025.100062 · Cited by 10

Regulation of Intestinal Permeability in Health and Disease: Possible Therapeutic Applications

Güemes-González, A. M., Arriaga‐Pizano, L., Chacón‐Salinas, R., Wong‐Baeza, I., & Ferat-Osorio, E. A. (2025) · Archives of Medical Research · doi:10.1016/j.arcmed.2025.103321 · Cited by 13

Magnetoelectric Coupling Stimulation Modulates Macrophage Reprogramming for Superior Infected Periodontal Tissue Regeneration

Liu, Z., Song, J., Heng, B. C., Yaojin, W. A. N. G., Xu, M., He, Y., Liu, Y. H., Deng, X., & Zhang, X. (2026) · Advanced Materials · doi:10.1002/adma.202517222 · Cited by 9

Elesclomol‐Loaded Cuprous Oxide Nanozymes with Dual‐Enzyme Activities for Implant‐Related Infection Therapy by Enhancing Bacterial Cuproptosis‐Like Death

Tao, E.-X., Sun, Y., Liu, Y., Shen, C., Wang, Y., & Wang, X. (2026) · Advanced Functional Materials · doi:10.1002/adfm.202524044 · Cited by 9

Enzyme therapy as a promising strategy to overcome multi-drug resistance in pathogens: current advances, key challenges, and future directions

Saini, S., Yadav, R., Das, R., & Singh, C. (2026) · RSC Advances · doi:10.1039/d5ra06932g · Cited by 9

Artificial Intelligence-Driven Discovery and Optimization of Antimicrobial Peptides Targeting ESKAPE Pathogens and Multidrug-Resistant Fungi

Wu-Mo, C., Flores-González, A., Meléndez-Delgado, J., Ortiz-Gómez, V., Meléndez-González, H., & Maldonado‐Hernández, R. (2026) · Microorganisms · doi:10.3390/microorganisms14030591 · Cited by 9

Evolution and rise of antimicrobial resistance in key public health bacteria within and across the One Health sectors

Izydorczyk, C., & Church, D. L. (2026) · Future Microbiology · doi:10.1080/17460913.2026.2633088 · Cited by 11

A novel antibacterial and anti-biofilm material: Biosynthetic silver nanoparticles mediated by extract from Oplopanax elatus adventitious roots

Liu, L., Fan, M.-Z., Hao, Y., Zhang, K., Piao, X., Jin, M., Lian, M.-L., & Jiang, J. (2023) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2023.111309 · Cited by 9

Antimicrobial Resistance: An Overview

Shah, S. N., Bhat, M. A., Bhat, M. A., & Jan, A. T. (2024) · Springer eBooks · doi:10.1007/978-981-97-2023-1_1 · Cited by 10

Nε-lysine acetylation of the histone-like protein HBsu influences antibiotic survival and persistence in Bacillus subtilis

Carr, R. A., Tucker, T., Newman, P. M., Jadalla, L., Jaludi, K., Reid, B. E., Alpheaus, D. N., Korrapati, A., Pivonka, A. E., & Carabetta, V. J. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1356733 · Cited by 9

Editorial: The Global Threats of Increasing Antimicrobial Resistance Require New Approaches to Drug Development, Including Molecular Antimicrobial Adjuvants

Parums, D. V. (2024) · Medical Science Monitor · doi:10.12659/msm.945583 · Cited by 9

Antifungal persistence: Clinical relevance and mechanisms

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Metatranscriptomic time series insight into antibiotic resistance genes and mobile genetic elements in wastewater systems under antibiotic selective pressure

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Skewed perception of personal behaviour as a contributor to antibiotic resistance and underestimation of the risks

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An evaluation of antimicrobial potency of silver nanoparticles synthesised from Fusarium sp.

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Combination of Lactiplantibacillus Plantarum ELF051 and Astragalus Polysaccharides Improves Intestinal Barrier Function and Gut Microbiota Profiles in Mice with Antibiotic-Associated Diarrhea

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Predicting Resistance to Small Molecule Kinase Inhibitors

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New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds

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