One-month repeatability of alcohol metabolism, sensitivity and acute tolerance
Abstract
Subjects (N = 34) in the Colorado Alcohol Research on Twins and Adoptees (CARTA) were brought back between 30 and 60 days after their initial testing to be retested on all the CARTA procedures. As before, subjects were given a dose of alcohol (.8 g/kg of body weight) calculated to bring their blood alcohol level (BAL) to near 100 mg/dl. Additional doses were given at the end of each of the next 2 hours to maintain their BAL near peak for approximately 3 hours. Repeatability (test-retest correlation) for alcohol clearance rate was near 0, with repeatabilities between .40 and .55 for peak BAL, time-to-peak BAL, average session BAL and relative volume of alcohol distribution. Repeatabilities of prealcohol baseline scores were generally high (median, .71) for the CARTA battery of physiological, motor coordination, perceptual speed and reaction time measures, but were only low to moderate for sensitivity scores (median, .27) and acute tolerance scores (median, .25) calculated on these measures. There was some evidence that repeatabilities for alcohol metabolism, sensitivity and acute tolerance were lower for women than for men.
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The few published test-retest studies of alcohol responses have included only brief between-session intervals with a focus on measurement reliability.
“The few published test-retest studies of alcohol responses have included only brief between-session intervals with a focus on measurement reliability(30, 31).”
From A Prospective 5-Year Re-examination of Alcohol Response in Heavy Drinkers Progressing in Alcohol Use Disorder (2016) · cites this paper as [31]
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O’Connor, S., Morzorati, S. L., Christian, J. C., & Li, T. (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03639.x · Cited by 159 · see citing works
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Anticipated and subjective sensitivities to alcohol.
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Kaiyala, K. J., Leroux, B. G., Watson, C. H., Prall, C. W., Coldwell, S. E., Woods, S. C., & Ramsay, D. S. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00488-9 · Cited by 15 · see citing works
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Yelland, L. N., Burns, J. P., Sims, D. N., et al. (2007) · Forensic Science International · doi:10.1016/j.forsciint.2007.05.011 · Cited by 13 · see citing works
Reproducibility of ethanol elimination rates in long-sleep and short-sleep mice.
Smolen, A., & Smolen, T. N. (1989) · Journal of Studies on Alcohol · doi:10.15288/jsa.1989.50.519 · Cited by 11 · see citing works
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Murray, J. B. (1989) · Psychological Reports · doi:10.2466/pr0.1989.64.2.627 · Cited by 11 · see citing works
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McClearn, G. E. (1993) · Behavior Genetics · doi:10.1007/bf01067427 · Cited by 9 · see citing works
Murray, C. H., Weafer, J. J., & de Wit, H. (2020) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2020.107989 · Cited by 8 · see citing works
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- Authors
- Wilson, J. R., & Nagoshi, C. T.
- Affiliations
- Alcohol Research Center, Institute for Behavioral Genetics, Boulder, Colorado.
- Venue
- Journal of Studies on Alcohol
- Publisher
- Alcohol Research Documentation, Inc.
- Published
- 1987-09
- Volume
- 48
- Issue
- 5
- Pages
- 437-442
- ISSN
- 0096-882X (ISSN-L)
- 1934-2683
- OpenAlex
- W2039925015
- Cited by
- 31
- References
- 0
- Citations by year
- 2020: 1 · 2015: 1
- FWCI
- 2.15
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Studies on Alcohol (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (AA03527)
- National Institute on Drug Abuse (DA-07043)
- National Center for Research Resources (RR-07013-20)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- alcohol metabolism, alcohol sensitivity, acute tolerance, test-retest reliability, blood alcohol concentration, motor coordination, reaction time, perceptual speed, sex differences
- MeSH terms
- Adoption, Adult, Ethanol, Alcoholic Intoxication, Behavior, Drug Tolerance, Female, Humans, Male, Time Factors, Twins
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