The relationship between glucocorticoid replacement and quality of life in 2737 hypopituitary patients

Ragnarsson, Oskar; Mattsson, Anders F; Monson, John P; Filipsson Nyström, Helena; Åkerblad, Ann-Charlotte; Kołtowska-Häggström, Maria; Johannsson, Gudmundur

doi:10.1530/eje-14-0397

The relationship between glucocorticoid replacement and quality of life in 2737 hypopituitary patients

Objective Quality of life (QoL) is impaired in hypopituitary patients and patients with primary adrenal insufficiency. The aim of this study was to analyse the impact of glucocorticoid (GC) replacement on QoL. The main hypothesis was that ACTH-insufficient patients experience a dose-dependent det…