The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Epigenetics and the germline
Open accessAbstract
Epigenetic processes affect three stages of germline development, namely (1) specification and formation of primordial germ cells and their germline derivatives through lineage-specific epigenetic modifications, in the same manner as other embryonic lineages are formed, (2) a largely genome-wide erasure and re-establishment of germline-specific epigenetic modifications that only occurs in the embryonic primordial germ cell lineage, followed by re-establishment of sex-specific patterns during gametogenesis, and (3) differential epigenetic modifications to the mature male and female gamete genomes shortly after fertilisation. This review will detail current knowledge of these three processes both at the genome-wide level and at specific imprinted loci. The consequences of epigenetic perturbation are discussed and new in vitro models which may allow further understanding of a difficult developmental period to study, especially in the human, are highlighted.
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Citations
Cites
DNA methylation patterns and epigenetic memory
Bird, A. (2002) · Genes & Development · doi:10.1101/gad.947102 · Cited by 7,124
Jaenisch, R., & Bird, A. (2003) · Nature Genetics · doi:10.1038/ng1089 · Cited by 6,325
Epigenetic Reprogramming in Mammalian Development
Reik, W., Dean, W., & Walter, J. (2001) · Science · doi:10.1126/science.1063443 · Cited by 3,078
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5293-5300.2003 · Cited by 2,019 · cited 1×
“A maternal hypermethylating diet during mouse pregnancy increased DNA methylation in repetitive sequences, promoting ectopic expression of the agouti gene (Waterland & Jirtle 2003).”
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
Walsh, C. P., Chaillet, J. R., & Bestor, T. H. (1998) · Nature Genetics · doi:10.1038/2413 · Cited by 1,105
Cited by
Environmental epigenomics and disease susceptibility
Jirtle, R. L., & Skinner, M. K. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2045 · Cited by 2,492
Epigenetic events in mammalian germ-cell development: reprogramming and beyond
Sasaki, H., & Matsui, Y. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2295 · Cited by 871
What is an epigenetic transgenerational phenotype?
Skinner, M. K. (2008) · Reproductive Toxicology · doi:10.1016/j.reprotox.2007.09.001 · Cited by 485
Lambrot, R., Xu, C., Saint-Phar, S., Chountalos, G., Cohen, T., Paquet, M., Suderman, M., Hallett, M., & Kimmins, S. (2013) · Nature Communications · doi:10.1038/ncomms3889 · Cited by 473
Epigenetic Transgenerational Actions of Endocrine Disruptors
Anway, M. D., & Skinner, M. K. (2006) · Endocrinology · doi:10.1210/en.2005-1058 · Cited by 455
Metadata
- Authors
- Allegrucci, C., Thurston, A., Lucas, E., & Young, L.
- Venue
- Reproduction
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-02-01
- Volume
- 129
- Issue
- 2
- Pages
- 137-149
- ISSN
- 1470-1626 (ISSN-L)
- 1741-7899
- OpenAlex
- W2034421167
- Cited by
- 221
- References
- 5
- FWCI
- 7.03
- Type
- journal article
- Language
- en
- Open access
- bronze
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