Epigenetic Transgenerational Actions of Endocrine Disruptors

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Okano, M., Bell, D. W., Haber, D. A., & Li, E. (1999) · Cell · doi:10.1016/s0092-8674(00)81656-6 · Cited by 6,143 · see citing works

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

Li, E., Bestor, T. H., & Jaenisch, R. (1992) · Cell · doi:10.1016/0092-8674(92)90611-f · Cited by 3,984 · see citing works

Epigenetic differences arise during the lifetime of monozygotic twins

Fraga, M. F., Ballestar, E., Paz, M. F., Ropero, S., Setien, F., Ballestar, M. L., Heine-Suñer, D., Cigudosa, J. C., Urioste, M., Benitez, J., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0500398102 · Cited by 3,602 · see citing works

Epigenetic Reprogramming in Mammalian Development

Reik, W., Dean, W., & Walter, J. (2001) · Science · doi:10.1126/science.1063443 · Cited by 3,078 · see citing works

Evidence for decreasing quality of semen during past 50 years.

Carlsen, E., Giwercman, A., Keiding, N., & Skakkebæk, N. E. (1992) · BMJ · doi:10.1136/bmj.305.6854.609 · Cited by 2,768 · see citing works

Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility

Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563 · see citing works

Estrogen Resistance Caused by a Mutation in the Estrogen-Receptor Gene in a Man

Smith, E. P., Boyd, J., Frank, G. R., Takahashi, H., Cohen, R. M., Specker, B., Williams, T. C., Lubahn, D. B., & Korach, K. S. (1994) · New England Journal of Medicine · doi:10.1056/nejm199410203311604 · Cited by 2,471 · see citing works

Genomic imprinting: parental influence on the genome

Reik, W., & Walter, J. (2001) · Nature Reviews Genetics · doi:10.1038/35047554 · Cited by 2,288 · see citing works

The Role of DNA Methylation in Mammalian Epigenetics

Jones, P. A., & Takai, D. (2001) · Science · doi:10.1126/science.1063852 · Cited by 2,063 · see citing works

Transposable elements: targets for early nutritional effects on epigenetic gene regulation

Waterland, R. A., & Jirtle, R. L. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.15.5293-5300.2003 · Cited by 2,019 · see citing works

Chromatin modification and epigenetic reprogramming in mammalian development

Li, E. (2002) · Nature Reviews Genetics · doi:10.1038/nrg887 · Cited by 1,900 · see citing works

Epigenetic inheritance at the agouti locus in the mouse

Morgan, H. D., Sutherland, H. G. E., Martin, D. I. K., & Whitelaw, E. (1999) · Nature Genetics · doi:10.1038/15490 · Cited by 1,476 · see citing works

Epigenetic reprogramming in mammals

Morgan, H. D., Santos, F., Green, K., Dean, W., & Reik, W. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi114 · Cited by 1,344 · see citing works

The genetics of autism

Muhle, R., Trentacoste, S. V., & Rapin, I. (2004) · Pediatrics · doi:10.1542/peds.113.5.e472 · Cited by 1,207 · see citing works

Epigenetic reprogramming in mouse primordial germ cells

Hájková, P., Erhardt, S., Lane, N., Haaf, T., El‐Maarri, O., Reik, W., Walter, J., & Surani, M. A. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(02)00181-8 · Cited by 1,190 · see citing works

Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period

Kaati, G., Bygren, L., & Edvinsson, S. (2002) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5200859 · Cited by 896 · see citing works

Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility

Eddy, E. M., Washburn, T. F., Bunch, D. O., Goulding, E. H., Gladen, B. C., Lubahn, D. B., & Korach, K. S. (1996) · Endocrinology · doi:10.1210/endo.137.11.8895349 · Cited by 866 · see citing works

Mechanisms of germ cell specification across the metazoans: epigenesis and preformation

Extavour, C. G. M., & Akam, M. E. (2003) · Development · doi:10.1242/dev.00804 · Cited by 785 · see citing works

The Plasticizer Diethylhexyl Phthalate Induces Malformations by Decreasing Fetal Testosterone Synthesis during Sexual Differentiation in the Male Rat

Parks, L. G. (2000) · Toxicological Sciences · doi:10.1093/toxsci/58.2.339 · Cited by 780 · see citing works

Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours

Esteller, M., & Herman, J. G. (2001) · The Journal of Pathology · doi:10.1002/path.1024 · Cited by 743 · see citing works

Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse

Lane, N., Dean, W., Erhardt, S., Hajkova, P., Surani, A., Walter, J., & Reik, W. (2003) · genesis · doi:10.1002/gene.10168 · Cited by 667 · see citing works

Transgenerational inheritance of epigenetic states at the murine Axin Fu allele occurs after maternal and paternal transmission

Rakyan, V. K., Chong, S., Blewitt, M. E., Cuthbert, P. C., Morgan, H. D., Luu, K. V. K., & Whitelaw, E. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0436776100 · Cited by 642 · see citing works

Postnatal Sex Reversal of the Ovaries in Mice Lacking Estrogen Receptors α and β

Couse, J. F., Hewitt, S. C., Bunch, D. O., Sar, M., Walker, V. R., Davis, B. J., & Korach, K. S. (1999) · Science · doi:10.1126/science.286.5448.2328 · Cited by 594 · see citing works

Environmental hormone disruptors: evidence that vinclozolin developmental toxicity is mediated by antiandrogenic metabolites

Kelce, W. R., Monosson, E., Gamcsik, M. P., Laws, S. C., & Gray, L. E. (1994) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1994.1117 · Cited by 542 · see citing works

Gestational and Lactational Exposure of Rats to Xenoestrogens Results in Reduced Testicular Size and Sperm Production

Sharpe, R. M., Fisher, J. S., Millar, M., Jobling, S., & Sumpter, J. P. (1995) · Environmental Health Perspectives · doi:10.1289/ehp.951031136 · Cited by 493 · see citing works

Epigenetics and cancer

Lund, A. H., & van Lohuizen, M. (2004) · Genes & Development · doi:10.1101/gad.1232504 · Cited by 489 · see citing works

Role of Estrogen Receptor Beta in Estrogen Action

Pettersson, K., & Gustafsson, J.-Α. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.165 · Cited by 489 · see citing works

Effects of Environmental Synthetic Chemicals on Thyroid Function

Brücker-Davis, F. (1998) · Thyroid · doi:10.1089/thy.1998.8.827 · Cited by 476 · see citing works

Diethylstilbestrol Revisited: A Review of the Long-Term Health Effects

Giusti, R. M., Iwamoto, K., & Hatch, E. E. (1995) · Annals of Internal Medicine · doi:10.7326/0003-4819-122-10-199505150-00008 · Cited by 451 · see citing works

Gene-specific timing and epigenetic memory in oocyte imprinting

Lucifero, D., Mann, M. R. W., Bartolomei, M. S., & Trasler, J. M. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddh104 · Cited by 443 · see citing works

Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome

Fisher, J. S. (2004) · Reproduction · doi:10.1530/rep.1.00025 · Cited by 429 · see citing works

Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells

Lee, J., Inoue, K., Ono, R., Ogonuki, N., Kohda, T., Kaneko‐Ishino, T., Ogura, A., & Ishino, F. (2002) · Development · doi:10.1242/dev.129.8.1807 · Cited by 421 · see citing works

EPIGENETICS AND HUMAN DISEASE

Jiang, Y.-H., Bressler, J., & Beaudet, A. L. (2004) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.5.061903.180014 · Cited by 365 · see citing works

Expression of oestrogen receptor beta (ER beta) in multiple rat tissues visualised by immunohistochemistry

Saunders, P. T. K., Maguire, S. M., Gaughan, J., & Millar, M. (1997) · Journal of Endocrinology · doi:10.1677/joe.0.154r013 · Cited by 355 · see citing works

Vinclozolin andp,p′-DDE Alter Androgen-Dependent Gene Expression:In VivoConfirmation of an Androgen Receptor-Mediated Mechanism

Kelce, W. R., Lambright, C. R., Gray, L. E., & Roberts, K. P. (1997) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1996.7966 · Cited by 353 · see citing works

The Fetal Basis of Amyloidogenesis: Exposure to Lead and Latent Overexpression of Amyloid Precursor Protein and β-Amyloid in the Aging Brain

Basha, R. M., Wei, W., Bakheet, S. A., Benitez, N. B., Siddiqi, H. K., Ge, Y., Lahiri, D. K., & Zawia, N. H. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4335-04.2005 · Cited by 353 · see citing works

Tissue Distribution of Estrogen Receptors Alpha (ER- ) and Beta (ER- ) mRNA in the Midgestational Human Fetus

Brandenberger, A. W., Tee, M. K., Lee, J. Y., Chao, V. A., & Jaffe, R. B. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.10.4400 · Cited by 335 · see citing works

Hypospadias in sons of women exposed to diethylstilbestrol in utero: a cohort study

Klip, H., Verloop, J., van Gool, J. D., Koster, M. E., Burger, C. W., & van Leeuwen, F. E. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08152-7 · Cited by 327 · see citing works

Sex differences in transgenerational alterations of growth and metabolism in progeny (F2) of female offspring (F1) of rats fed a low protein diet during pregnancy and lactation

Zambrano, E., Martínez‐Samayoa, P. M., Bautista, C. J., Deás, M., Guillén-Pineda, L. E., Rodríguez-González, G. L., Guzmán, C., Larrea, F., & Nathanielsz, P. W. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.086462 · Cited by 325 · see citing works

Reproductive impairment in the Florida panther: nature or nurture?

Facemire, C., Gross, T., & Guillette, L. (1995) · Environmental Health Perspectives · doi:10.1289/ehp.103-1519283 · Cited by 297 · see citing works

A and B forms of the androgen receptor are expressed in a variety of human tissues

Wilson, C. M., & McPhaul, M. J. (1996) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(96)03819-1 · Cited by 267 · see citing works

Permanent Effects of Neonatal Estrogen Exposure in Rats on Reproductive Hormone Levels, Sertoli Cell Number, and the Efficiency of Spermatogenesis in Adulthood1

Atanassova, N. N., McKinnell, C., Walker, M., Turner, K. J., Fisher, J. S., Morley, M., Millar, M. R., Groome, N. P., & Sharpe, R. M. (1999) · Endocrinology · doi:10.1210/endo.140.11.7108 · Cited by 251 · see citing works

Epigenetic inheritance in the mouse

Römer, I., Reik, W., Dean, W., & Klose, J. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00124-2 · Cited by 248 · see citing works

Epigenetic germline inheritance

Chong, S., & Whitelaw, E. (2004) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2004.09.001 · Cited by 239 · see citing works

Assisted reproduction: the epigenetic perspective

Horsthemke, B., & Ludwig, M. Z. (2005) · Human Reproduction Update · doi:10.1093/humupd/dmi022 · Cited by 224 · see citing works

Epigenetics and the germline

Allegrucci, C., Thurston, A., Lucas, E. S., & Young, L. E. (2005) · Reproduction · doi:10.1530/rep.1.00360 · Cited by 219 · see citing works

Regulation of Rat Testis Gonocyte Proliferation by Platelet-Derived Growth Factor and Estradiol: Identification of Signaling Mechanisms Involved

Li, H., Papadopoulos, V., Vidić, B., Dym, M., & Culty, M. (1997) · Endocrinology · doi:10.1210/endo.138.3.5021 · Cited by 207 · see citing works

Methoxychlor as a Model for Environmental Estrogens

Cummings, A. M. (1997) · Critical Reviews in Toxicology · doi:10.3109/10408449709089899 · Cited by 207 · see citing works

Environmental xenoestrogens, antiandrogens and disorders of male sexual differentiation

Sultan, C., Balaguer, P., Térouanne, B., Georget, V., Paris, F., Jeandel, C., Lumbroso, S., & Nicolas, J. (2001) · Molecular and Cellular Endocrinology · doi:10.1016/s0303-7207(01)00430-0 · Cited by 206 · see citing works

Elevated mutation rates in the germ line of first- and second-generation offspring of irradiated male mice

Barber, R. C., Plumb, M., Boulton, E., Roux, I., & Dubrova, Y. E. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.102015399 · Cited by 200 · see citing works

Radiation-induced transgenerational instability

Dubrova, Y. E. (2003) · Oncogene · doi:10.1038/sj.onc.1206993 · Cited by 192 · see citing works

The developmental pattern of androgen receptor expression in rat prostate lobes is altered after neonatal exposure to estrogen.

Prins, G. S., & Birch, L. A. (1995) · Endocrinology · doi:10.1210/endo.136.3.7867585 · Cited by 188 · see citing works

Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning

Yamazaki, Y., Mann, M. R. W., Lee, S. S., Marh, J., McCarrey, J. R., Yanagimachi, R., & Bartolomei, M. S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2035119100 · Cited by 170 · see citing works

Immunotoxicity of pesticides: a review

Blakley, B. R., Brousseau, P., Fournier, M., & Voccia, I. (1999) · Toxicology and Industrial Health · doi:10.1177/074823379901500110 · Cited by 166 · see citing works

Effects of bisphenol a on the reproduction of Japanese medaka (Oryzias latipes)

Kang, I. J., Yokota, H., Oshima, Y., Tsuruda, Y., Oe, T., Imada, N., Tadokoro, H., & Honjo, T. (2002) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620211119 · Cited by 159 · see citing works

Estrogenic Induction of Spermatogenesis in the Hypogonadal Mouse

Ebling, F. J. P., Brooks, A. N., Cronin, A. S., Ford, H., & KERR, J. B. (2000) · Endocrinology · doi:10.1210/endo.141.8.7596 · Cited by 157 · see citing works

Suppression of Androgen Action and the Induction of Gross Abnormalities of the Reproductive Tract in Male Rats Treated Neonatally With Diethylstilbestrol

McKinnell, C., Atanassova, N. N., Williams, K., Fisher, J. S., Walker, M., Turner, K. J., Saunders, P. T. K., & Sharpe, R. M. (2001) · Journal of Andrology · doi:10.1002/j.1939-4640.2001.tb02186.x · Cited by 152 · see citing works

Effect of the anti-androgenic endocrine disruptor vinclozolin on embryonic testis cord formation and postnatal testis development and function

Uzumcu, M., Suzuki, H., & Skinner, M. K. (2004) · Reproductive Toxicology · doi:10.1016/j.reprotox.2004.05.008 · Cited by 143 · see citing works

Hsp90 and environmental impacts on epigenetic states: a model for the trans-generational effects of diethylstibesterol on uterine development and cancer

Ruden, D. M., Xiao, L., Garfinkel, M. D., & Lu, X. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi103 · Cited by 139 · see citing works

Estrogen Receptor α Has a Functional Role in the Mouse Rete Testis and Efferent Ductules1

Lee, K., Hess, R. A., Bahr, J. M., Lubahn, D. B., Taylor, J. A., & Bunick, D. (2000) · Biology of Reproduction · doi:10.1095/biolreprod63.6.1873 · Cited by 135 · see citing works

Quantitative analysis of the intrinsic muscles of the foot

Kura, H., Luo, Z.-P., Kitaoka, H. B., & An, K. (1997) · The Anatomical Record · doi:10.1002/(sici)1097-0185(199709)249:1 · Cited by 124 · see citing works

Neophenogenesis: A developmental theory of phenotypic evolution

Johnston, T. D., & Gottlieb, G. (1990) · Journal of Theoretical Biology · doi:10.1016/s0022-5193(05)80260-7 · Cited by 120 · see citing works

How estrogenic is nonylphenol?

Schwaiger, J., Mallow, U., Ferling, H., Knoerr, S., Braunbeck, T., Kalbfus, W., & Negele, R. D. (2002) · Aquatic Toxicology · doi:10.1016/s0166-445x(01)00248-x · Cited by 119 · see citing works

Programmed disorders of β-cell development and function as one cause for type 2 diabetes? The GK rat paradigm

Portha, B. (2005) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.566 · Cited by 117 · see citing works

Relativity for molecular clocks

Penny, D. (2005) · Nature · doi:10.1038/436183a · Cited by 117 · see citing works

Immunolocalisation of androgen receptor to interstitial cells in fetal rat testes and to mesenchymal and epithelial cells of associated ducts

Majdič, G., Millar, M. R., & Saunders, P. T. K. (1995) · Journal of Endocrinology · doi:10.1677/joe.0.1470285 · Cited by 112 · see citing works

Pluripotential stem cells derived from migrating primordial germ cells

Durcova‐Hills, G., Ainscough, J., & McLaren, A. L. D. (2001) · Differentiation · doi:10.1046/j.1432-0436.2001.680409.x · Cited by 104 · see citing works

Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance

Cook, J., Davis, B. J., Cai, S., Barrett, J. C., Conti, C. J., & Walker, C. L. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0503218102 · Cited by 102 · see citing works

DNA methylation and epigenetic mechanisms

Holliday, R. (1989) · Cell Biophysics · doi:10.1007/bf02991575 · Cited by 99 · see citing works

Familial aggregation of abnormal methylation of parental alleles at the IGF2/H19 and IGF2R differentially methylated regions

Sandovici, I. (2003) · Human Molecular Genetics · doi:10.1093/hmg/ddg167 · Cited by 98 · see citing works

Reproductive and transgenerational effects of methylmercury or Aroclor 1268 onFundulus heteroclitus

Matta, M. B., Linse, J., Cairncross, C., Francendese, L., & Kocan, R. M. (2001) · Environmental Toxicology and Chemistry · doi:10.1002/etc.5620200213 · Cited by 96 · see citing works

Ovarian Carcinoma in an Adolescent With Transgenerational Exposure to Diethylstilbestrol

Blatt, J., Le, L. V., Weiner, T. M., & Sailer, S. L. (2003) · Journal of Pediatric Hematology/Oncology · doi:10.1097/00043426-200308000-00009 · Cited by 96 · see citing works

Erasure of methylation imprinting of Igf2r during mouse primordial germ‐cell development

Sato, S., Yoshimizu, T., Sato, E., & Matsui, Y. (2003) · Molecular Reproduction and Development · doi:10.1002/mrd.10264 · Cited by 94 · see citing works

Are Humans Still Evolving?

Balter, M. (2005) · Science · doi:10.1126/science.309.5732.234 · Cited by 85 · see citing works

Seminiferous Cord Formation and Germ‐Cell Programming: Epigenetic Transgenerational Actions of Endocrine Disruptors

Skinner, M. K., & Anway, M. D. (2005) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1336.004 · Cited by 84 · see citing works

Androgens and environmental antiandrogens affect reproductive development and play behavior in the Sprague-Dawley rat.

Hotchkiss, A. K., Ostby, J. S., Vandenburgh, J. G., & Gray, L. E. (2002) · Environmental Health Perspectives · doi:10.1289/ehp.02110s3435 · Cited by 82 · cited 1× · see citing works

Epigenetic Regulation of Aging in Honeybee Workers

Omholt, S. W., & Amdam, G. V. (2004) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2004.26.pe28 · Cited by 79 · see citing works

Reproductive epigenetics

Kelly, T., & Trasler, J. M. (2004) · Clinical Genetics · doi:10.1111/j.0009-9163.2004.00236.x · Cited by 79 · see citing works

Epigenetic and gene expression changes related to transgenerational carcinogenesis

Cheng, R. Y. S., Hockman, T. M., Crawford, E. B., Anderson, L. M., & Shiao, Y. (2004) · Molecular Carcinogenesis · doi:10.1002/mc.20022 · Cited by 79 · see citing works

Parents’ Growth in Childhood and the Birth Weight of Their Offspring

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Transgenerational effects of drug and hormonal treatments in mammals: a review of observations and ideas

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Neonatal exposure to estrogen differentially alters estrogen receptor alpha and beta mRNA expression in rat testis during postnatal development

Tena‐Sempere, M., Navarro, J., Pinilla, L., Gonzalez, L., Huhtaniemi, I. T., & Aguilar, E. (2000) · Journal of Endocrinology · doi:10.1677/joe.0.1650345 · Cited by 72 · see citing works

Ontogeny of oestrogen receptor alpha in gonads and sex ducts of fetal and newborn mice

Nielsen, M. B., Björnsdóttir, S., Høyer, P. E., & Byskov, A. G. (2000) · Reproduction · doi:10.1530/jrf.0.1180195 · Cited by 70 · see citing works

Comparison of the Developmental and Reproductive Toxicity of Diethylstilbestrol Administered to Rats in Utero, Lactationally, Preweaning, or Postweaning

Odum, J. (2002) · Toxicological Sciences · doi:10.1093/toxsci/68.1.147 · Cited by 69 · see citing works

Environmental signaling and evolutionary change: can exposure of pregnant mammals to environmental estrogens lead to epigenetically induced evolutionary changes in embryos?

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Effect of Transient Embryonic In Vivo Exposure to the Endocrine Disruptor Methoxychlor on Embryonic and Postnatal Testis Development

Cupp, A. S., Uzumcu, M., Suzuki, H., Dirks, K. A., Phillips, B., & Skinner, M. K. (2003) · Journal of Andrology · doi:10.1002/j.1939-4640.2003.tb02736.x · Cited by 68 · see citing works

Transgenerational and Developmental Exposure of Japanese Medaka (Oryzias latipes) to Ethinylestradiol Results in Endocrine and Reproductive Differences in the Response to Ethinylestradiol as Adults

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Neuroendocrine and reproductive effects of contemporary-use pesticides

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Maternal transfer efficiency and transgenerational toxicity of methylmercury in Daphnia magna

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Effects of in Utero Exposure to the Organophosphate Insecticide Fenitrothion on Androgen-Dependent Reproductive Development in the Crl:CD(SD)BR Rat

Turner, K. J. (2002) · Toxicological Sciences · doi:10.1093/toxsci/68.1.174 · Cited by 60 · see citing works

Endocrine Disruption and Hypospadias

Steinhardt, G. F. (2004) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-8995-6_13 · Cited by 56 · see citing works

Effects of hypoxia acclimation on morpho-physiological traits over three generations of Daphnia magna

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The fetal basis of adult disease: Role of environmental exposures?introduction

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Effects of short-term exposure to hydroxyflutamide in utero on the development of the reproductive tract in male mice

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Repeated in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure affects male gonads in offspring, leading to sex ratio changes in F2 progeny

Ikeda, M., Tamura, M., Yamashita, J., Suzuki, C., & Tomita, T. (2005) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2004.11.019 · Cited by 54 · see citing works

DNA methylation and male infertility

Francisco, J. C. (2004) · Frontiers in bioscience · doi:10.2741/1332 · Cited by 49 · see citing works

Transgenerational Effects of Preconception Paternal Contamination with55Fe

Hoyes, K. P., Lord, B. I., McCann, C., Hendry, J. H., & Morris, I. D. (2001) · Radiation Research · doi:10.1667/0033-7587(2001)156[0488:teoppc]2.0.co;2 · Cited by 43 · see citing works

Neonatal Imprinting and Regulation of Estrogen Receptor Alpha and Beta mRNA Expression by Estrogen in the Pituitary and Hypothalamus of the Male Rat

Tena‐Sempere, M., González, L. C., Pinilla, L., Huhtaniemi, I. T., & Aguilar, E. (2001) · Neuroendocrinology · doi:10.1159/000054616 · Cited by 42 · see citing works

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The EDKB: an established knowledge base for endocrine disrupting chemicals

Ding, D., Xu, L., Fang, H., Hong, H., Perkins, R., Harris, S., Bearden, E. D., Shi, L. M., & Tong, W. (2010) · BMC Bioinformatics · doi:10.1186/1471-2105-11-s6-s5 · Cited by 99 · see citing works

Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations

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Environmental exposures and gene regulation in disease etiology

Edwards, T. M., & Myers, J. P. (2008) · Ciência & Saúde Coletiva · doi:10.1590/s1413-81232008000100030 · Cited by 98 · see citing works

Transgenerational Effects of Bisphenol A on Gene Expression and DNA Methylation of Imprinted Genes in Brain

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Genetic variation, inbreeding and chemical exposure—combined effects in wildlife and critical considerations for ecotoxicology

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Analyzing the cancer methylome through targeted bisulfite sequencing

Lee, E.-J., Luo, J., Wilson, J. M., & Shi, H. (2012) · Cancer Letters · doi:10.1016/j.canlet.2012.10.040 · Cited by 89 · see citing works

Chemical Geographies

Romero, A. M., Guthman, J., Galt, R. E., Huber, M., Mansfield, B., & Sawyer, S. (2017) · GeoHumanities · doi:10.1080/2373566x.2017.1298972 · Cited by 87 · see citing works

Persistent Adverse Effects on Health and Reproduction Caused by Exposure of Zebrafish to 2,3,7,8-Tetrachlorodibenzo-p-dioxin During Early Development and Gonad Differentiation

Heiden, T. C. K., Spitsbergen, J. M., Heideman, W., & Peterson, R. E. (2009) · Toxicological Sciences · doi:10.1093/toxsci/kfp048 · Cited by 87 · see citing works

LINE ‐1 hypomethylation in spermatozoa is associated with Bisphenol A exposure

Miao, M., Zhou, X., Li, Y., Zhang, O. G. H., Zhou, Z., Li, T., Yuan, W., Li, R., & Li, D. (2013) · Andrology · doi:10.1111/j.2047-2927.2013.00166.x · Cited by 88 · see citing works

Global and gene specific DNA methylation changes during zebrafish development

Fang, X., Corrales, J., Thornton, C., Scheffler, B. E., & Willett, K. L. (2013) · Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology · doi:10.1016/j.cbpb.2013.07.007 · Cited by 86 · see citing works

DNA methylation alterations in response to pesticide exposure in vitro

Zhang, X., Wallace, A. D., Du, P., Kibbe, W. A., Jafari, N., Xie, H., Lin, S. M., Baccarelli, A., Soares, M. B., & Hou, L. (2012) · Environmental and Molecular Mutagenesis · doi:10.1002/em.21718 · Cited by 86 · see citing works

Epigenetic legacy of parental experiences: Dynamic and interactive pathways to inheritance

Champagne, F. A. (2016) · Development and Psychopathology · doi:10.1017/s0954579416000808 · Cited by 80 · see citing works

Endocrine disruptors from the environment affecting breast cancer (Review)

Calaf, G. M., Ponce‐Cusi, R., Aguayo, F., Mu�oz, J., & Bleak, T. C. (2020) · Oncology Letters · doi:10.3892/ol.2020.11566 · Cited by 92 · see citing works

Direct and transgenerational effects of low doses of perinatal di-(2-ethylhexyl) phthalate (DEHP) on social behaviors in mice

Quinnies, K. M., Harris, E. P., Snyder, R. W., Sumner, S. S., & Rissman, E. F. (2017) · PLOS ONE · doi:10.1371/journal.pone.0171977 · Cited by 84 · see citing works

Endocrine disrupting chemicals and reproductive disorders in women, men, and animal models

Laws, M. J., Neff, A. M., Brehm, E., Warner, G. R., & Flaws, J. A. (2021) · Advances in pharmacology · doi:10.1016/bs.apha.2021.03.008 · Cited by 85 · see citing works

Male fetal germ cells are targets for androgens that physiologically inhibit their proliferation

Merlet, J., Racine, C., Moreau, E., Moreno, S. G., & Habert, R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611421104 · Cited by 81 · see citing works

Gonadotropin stimulation contributes to an increased incidence of epimutations in ICSI-derived mice

de Waal, E., Yamazaki, Y., Ingale, P., Bartolomei, M. S., Yanagimachi, R., & McCarrey, J. R. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds287 · Cited by 81 · see citing works

Epigenetic Transgenerational Actions of Endocrine Disruptors and Male Fertility

Anway, M. D., Cupp, A. S., Uzumcu, M., & Skinner, M. K. (2005) · Science · doi:10.1126/science.1108190 · Cited by 2,563 · see citing works

Epigenetic Transgenerational Effects of Endocrine Disruptors on Male Reproduction

Guerrero‐Bosagna, C., & Skinner, M. K. (2009) · Seminars in Reproductive Medicine · doi:10.1055/s-0029-1237428 · Cited by 80 · see citing works

Epigenetic programming of the germ line: effects of endocrine disruptors on the development of transgenerational disease

Anway, M. D., & Skinner, M. K. (2008) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60553-6 · Cited by 167 · see citing works

Transgenerational epigenetic actions of environmental compounds.

Guerrero‐Bosagna, C., & Skinner, M. K. (2010) · Animal Reproduction · Cited by 2 · see citing works

Endocrine Disruptor Vinclozolin Induced Epigenetic Transgenerational Adult-Onset Disease

Anway, M. D., Leathers, C. W., & Skinner, M. K. (2006) · Endocrinology · doi:10.1210/en.2006-0640 · Cited by 557 · see citing works