The effect of orthostatic training in the prevention of vasovagal syncope and its influencing factors
Open accessAbstract
Recently orthostatic training has been proposed as an effective treatment for vasovagal syncope, even though some patients may relapse. This study was undertaken to assess the effect of orthostatic training on patients with vasovagal syncope and its influencing factors. The study group comprised 125 consecutive patients (51 males and 74 females), aged 40 +/- 19 years, with a history of syncope and a positive head-up tilt test. They were randomized into an orthostatic training group (64 patients) and a no treatment group (controls, 61 patients). The training programme consisted of daily 30-minute sessions of upright standing against a vertical wall 6 days a week for at least 4 weeks. After one year of follow-up, 45 (72.6%) of 62 orthostatic trained patients reported no syncopal recurrence, while only 22 of 61 controls (36.1%, P < 0.05) reported the same. Furthermore, in the training group, the patients with recurrence were older, and the number of syncopal spells in the preceding year was less than in the patients with no recurrence in the same group. Orthostatic training is an effective therapy for the prevention of vasovagal syncope. This kind of therapy was of greater benefit to patients who were younger or experienced frequent spells of syncope.
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Some studies suggested modest benefit with outpatient tilt training.
“While some studies suggested modest benefit with outpatient tilt training, 266,267”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [266]
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Connolly, S. J., Sheldon, R., Thorpe, K. E., Roberts, R. S., Ellenbogen, K. A., Wilkoff, B. L., Morillo, C., Gent, M., & for the VPS II Investigators (2003) · JAMA · doi:10.1001/jama.289.17.2224 · Cited by 500 · see citing works
Sutton, R., Brignole, M., Menozzi, C., Raviele, A., Alboni, P., Giani, P., & Moya, A. (2000) · Circulation · doi:10.1161/01.cir.102.3.294 · Cited by 407 · see citing works
Ammirati, F., Colivicchi, F., & Santini, M. (2001) · Circulation · doi:10.1161/hc2601.091708 · Cited by 299 · see citing works
Vagal and sympathetic mechanisms in patients with orthostatic vasovagal syncope
Morillo, C. A., Eckberg, D. L., Ellenbogen, K. A., Beightol, L. A., Hoag, J. B., Tahvanainen, K. U. O., Kuusela, T. A., & Diedrich, A. M. (1997) · Circulation · doi:10.1161/01.cir.96.8.2509 · Cited by 280 · see citing works
Proposed classification for tilt induced vasovagal syncope
Sutton, R. B. (1992) · Medical Entomology and Zoology · Cited by 230 · see citing works
Madrid, A. H., Ortega, J., Rebollo, J. G., Manzano, J. G., Segovia, J. G., Sánchez, A., Peña, G., & Moro, C. (2001) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)01155-4 · Cited by 205 · see citing works
Girolamo, E. D., Iorio, C. D., Leonzio, L., Sabatini, P., & Barsotti, A. (1999) · Circulation · doi:10.1161/01.cir.100.17.1798 · Cited by 178 · see citing works
A controlled trial of acute and long-term medical therapy in tilt-induced neurolly mediated syncope
Brignole, M., Menozzi, C., Gianfranchi, L., LOLLI, G., Bottoni, N., & Oddone, D. (1992) · The American Journal of Cardiology · doi:10.1016/0002-9149(92)90615-6 · Cited by 172 · see citing works
Ector, H., Reybrouck, T., Heidbüchel, H., Gewillig, M. H. M. L., & de Werf, F. V. (1998) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1998.tb01087.x · Cited by 163 · see citing works
Pathophysiological Aspects of Neurocardiogenic Syncope: Current Concepts and New Perspectives
KOSINSKI, D. J., Grubb, B. P., & Temesy‐Armos, P. N. (1995) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1995.tb04666.x · Cited by 140 · see citing works
Efficacy of tilt training in the treatment of neurally mediated syncope. A randomized study
Foglia-Manzillo, G. (2004) · Europace · doi:10.1016/j.eupc.2004.01.002 · Cited by 127 · see citing works
Tilt Training: A Treatment for Malignant and Recurrent Neurocardiogenic Syncope
Reybrouck, T., Heidbüchel, H., de Werf, F. V., & Ector, H. (2000) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2000.tb00833.x · Cited by 78 · see citing works
Adenosine Receptor Subtypes Mediating Coronary Vasodilation in Rat Hearts
Hinschen, A. K., Rose’Meyer, R. B., & Headrick, J. P. (2003) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200301000-00010 · Cited by 78 · see citing works
Is home orthostatic self-training effective in preventing neurally mediated syncope?
ON, Y. K., PARK, J., HUH, J., & SOO KIM, J. (2007) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2007.00725.x · Cited by 78 · see citing works
Age and hemodynamic responses to tilt testing in those with syncope of unknown origin
Kurbaan, A. S., Bowker, T. J., Wijesekera, N. T., Franzén, A.-C., Heaven, D., Itty, S., & Sutton, R. (2003) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)02967-4 · Cited by 56 · see citing works
Efficacy of Orthostatic Self‐Training in Medically Refractory Neurocardiogenic Syncope
Abe, H., Kohshi, K., & Nakashima, Y. (2003) · Clinical and Experimental Hypertension · doi:10.1081/ceh-120025332 · Cited by 23 · see citing works
Abe, H., Sumiyoshi, M., Kohshi, K., & Nakashima, Y. (2003) · Clinical and Experimental Hypertension · doi:10.1081/ceh-120019151 · Cited by 20 · see citing works
Successful Treatment of Malignant Neurocardiogenic Syncope With Repeated Tilt Training Program
Numata, T., Abe, H., Nagatomo, T., et al. (2000) · Japanese Circulation Journal-english Edition · doi:10.1253/jcj.64.406 · Cited by 19 · see citing works
Abe, H., Kohshi, K., & Nakashima, Y. (2003) · PubMed · Cited by 10 · see citing works
Suzuki, M., Hori, S., Tomita, Y., & Aikawa, N. (2006) · Circulation Journal · doi:10.1253/circj.70.902 · Cited by 9 · see citing works
Home Orthostatic Self‐Training in Neurocardiogenic Syncope
Abe, H., Kohshi, K., & Nakashima, Y. (2005) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.2005.00023.x · Cited by 9 · see citing works
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Research works printed but not linked: 1
- Guo Lifen. Tilt training: New method to treat vasovagal syncope. Chinese Journal of Pacing and Cardiac Elec- trical Physiology 2006; 6: 530-1.
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2018 ESC Guidelines for the diagnosis and management of syncope
Brignole, M., Moya, A., de Lange, F. J., Deharo, J.-C., Elliott, P. M., Fanciulli, A., Fedorowski, A., Furlan, R., Kenny, R. A., Martín, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy037 · Cited by 1,951 · see citing works
Tan, M. P., Newton, J. L., Chadwick, T. J., Gray, J. C., Nath, S., & Parry, S. W. (2010) · Europace · doi:10.1093/europace/eup368 · Cited by 58 · see citing works
Are treatments for vasovagal syncope effective? A meta-analysis
Vyas, A., Swaminathan, P. D., Zimmerman, M. B., & Olshansky, B. (2013) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.04.144 · Cited by 44 · see citing works
- Authors
- Zeng, H., Ge, K., Zhang, W., Wang, G., & Guo, L.
- Affiliations
- Peking University Third Hospital (CN)
- Venue
- International Heart Journal
- Published
- 2008
- Volume
- 49
- Issue
- 6
- Pages
- 707-712
- ISSN
- 1349-2365 (ISSN-L)
- 1349-3299
- OpenAlex
- W1972619801
- Cited by
- 32
- References
- 21
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 3 · 2019: 5 · 2018: 5 · 2017: 3 · 2016: 1 · 2014: 2 · 2013: 1 · 2012: 1
- FWCI
- 1.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- orthostatic training, vasovagal syncope, syncope prevention, head-up tilt, syncope recurrence, risk factors
- MeSH terms
- Adult, Female, Humans, Male, Physical Education and Training, Tilt-Table Test, Syncope, Vasovagal
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