The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Reversal of Parenteral Nutrition–Associated Liver Disease in Two Infants With Short Bowel Syndrome Using Parenteral Fish Oil: Implications for Future Management
Abstract
Here we report the reversal of cholestasis in 2 infants with intestinal failure and parenteral nutrition–associated liver disease. Treatment involved the substitution of a conventional intravenous fat emulsion with one containing primarily omega-3 fatty acids. Biochemical tests of liver function improved significantly. One child was removed from the liver transplantation list because of improved hepatic function, and the second child had complete resolution of cholestasis while solely on parenteral nutrition. This suggests that fat emulsions made from fish oils may be an effective means of treating and preventing this often-fatal condition. A randomized, controlled trial is necessary to study the efficacy of this new approach to parenteral nutrition–associated liver disease.
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Citations
Cites
Steatohepatitis: A tale of two “hits”?
Day, C. P., & James, O. F. W. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70599-2 · Cited by 4,285
ARAYA, J., RODRIGO, R., VIDELA, L. A., THIELEMANN, L., ORELLANA, M., PETTINELLI, P., & PONIACHIK, J. (2004) · Clinical Science · doi:10.1042/cs20030326 · Cited by 700
Cited by
Gura, K. M., Lee, S., Valim, C., Zhou, J., Kim, S., Modi, B. P., Arsenault, D. A., Strijbosch, R. A. M., Lopes, S., Duggan, C., et al. (2008) · Pediatrics · doi:10.1542/peds.2007-2248 · Cited by 455
Self-citationOverview of Pediatric Short Bowel Syndrome
Duro, D., Kamin, D., & Duggan, C. (2008) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3181819007 · Cited by 147
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Metadata
- Authors
- Gura, K. M., Duggan, C. P., Collier, S. B., Jennings, R. W., Folkman, J., Bistrian, B. R., & Puder, M.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2006-07-01
- Volume
- 118
- Issue
- 1
- Pages
- e197-e201
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2015480392
- Cited by
- 344
- References
- 2
- FWCI
- 18.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Gura, K. M., Duggan, C. P., Collier, S. B., Jennings, R. W., Folkman, J., Bistrian, B. R., & Puder, M. (2006). Reversal of Parenteral Nutrition–Associated Liver Disease in Two Infants With Short Bowel Syndrome Using Parenteral Fish Oil: Implications for Future Management. Pediatrics. https://doi.org/10.1542/peds.2005-2662
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
