CoChat
Sign Up
Cited by 330Child Abuse and TraumaObesity, Physical Activity, DietBirth, Development, and Health

The DOI matches its Crossref record; 58 of the 59 references it cites were found in a registry or an index.

Obesity and Type 2 Diabetes Risk in Midadult Life: The Role of Childhood Adversity

Thomas, Claudia, Hyppönen, Elina, Power, Chris·2008·Pediatrics
DOI 10.1542/peds.2007-2403
Open this paper in CoChat — free account

Abstract

OBJECTIVE. Child abuse has been associated with poorer physical health in adulthood, but less is known about childhood adversity more broadly, including neglect and family problems, or the pathways from adversity to adult disease. We have examined how different stressful emotional or neglectful childhood adversities are related to adiposity and glucose control in midadulthood, taking into account childhood factors, and whether the relationships are mediated by adult health behaviors and socioeconomic position. METHODS. This was a prospective longitudinal study of 9310 members of the 1958 British birth cohort who participated in a biomedical interview at 45 years of age. Primary outcomes consisted of continuous measures of BMI, waist circumference, and glycosylated hemoglobin at 45 years and categorical indicators: total obesity (BMI ≥ 30), central obesity (waist circumference: ≥102 cm for men and ≥88 cm for women), and glycosylated hemoglobin level of ≥6. RESULTS. The risk of obesity increased by 20% to 50% for several adversities (physical abuse, verbal abuse, witnessed abuse, humiliation, neglect, strict upbringing, physical punishment, conflict or tension, low parental aspirations or interest in education, hardly takes outings with parents, and father hardly reads to child). Adversities with the strongest associations with adiposity (eg, physical abuse) tended to be associated with glycosylated hemoglobin levels of ≥6, but in most cases associations were explained by adjustment for adulthood mediators such as adiposity. Effects of other adversities reflecting less severe emotional neglect and family environment were largely explained by childhood socioeconomic factors. CONCLUSIONS. Some childhood adversities increase the risk of obesity in adulthood and thereby increase the risk for type 2 diabetes. Research is needed to understand the interrelatedness of adversities, the social context of their occurrence, and trajectories from adversity to adult disease.

Overview

Integrity signals

Registry

Crossref · 10.1542/peds.2007-2403

Cites

58 of 58 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 59 references

1 of the 59 references couldn’t be matched to a known paper.

Research works printed but not linked: 1

  1. Rothman KJ, Greenland S. Modern Epidemiology. 2nd ed. Philadelphia, PA: Lippincott, Williams & Wilkins; 1998

Cited by

Sorted by citations

Items 201–300 of 329

Related

See all

Metadata

Authors
Thomas, C., Hyppönen, E., & Power, C.
Affiliations
  • University College London (GB)
  • Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, United Kingdom
Corresponding author
Thomas, Claudia
ORCID
Venue
Pediatrics
Publisher
American Academy of Pediatrics (AAP)
Published
2008-05-01
Volume
121
Issue
5
Pages
e1240-e1249
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
DOI
10.1542/peds.2007-2403
OpenAlex
W2106821860
Cited by
330
References
59
Citations by year
2026: 2 · 2025: 6 · 2024: 9 · 2023: 12 · 2022: 15 · 2021: 19 · 2020: 18 · 2019: 29 · 2018: 14 · 2017: 32 · 2016: 19 · 2015: 28 · 2014: 17 · 2013: 26 · 2012: 22
FWCI
22.71
Type
journal article
Language
en
Open access
closed
Locations
  • PEDIATRICS (publishedVersion)
  • PubMed (publishedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
National Institute for Health and Care Research (PHCS/C4/4/016)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
Keywords
childhood adversity, childhood abuse, child neglect, type 2 diabetes risk, obesity, adiposity, abdominal obesity, HbA1c, glycemic control, physical abuse, verbal abuse, humiliation, parenting, family environment, socioeconomic position, 1958 British birth cohort
MeSH terms
Adolescent, Child, Child Abuse, Diabetes Mellitus, Type 2, Family Relations, Female, Glycated Hemoglobin, Humans, Male, Middle Aged, Obesity, Cohort Studies, Body Mass Index, Child of Impaired Parents, Parenting, Adult Survivors of Child Abuse

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review