The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Effect of Hypothermia on Amplitude-Integrated Electroencephalogram in Infants With Asphyxia
Abstract
OBJECTIVES: Amplitude-integrated electroencephalogram (aEEG) at <6 hours is the best single outcome predictor in term infants with perinatal asphyxia at normothermia. Hypothermia has been used to treat those infants and proved to improve their outcome. The objectives of this study were to compare the predictive value of aEEG at <6 hours on outcomes in normothermia- and hypothermia-treated infants and to investigate the best outcome predictor (time to normal trace or sleep–wake cycling [SWC]) in normothermia- and hypothermia-treated infants. METHODS: Seventy-four infants were recruited by using the CoolCap entry criteria, and their outcomes were assessed by using the Bayley Scales of Infant Development II at 18 months. The aEEG was recorded for 72 hours. Patterns and voltages of aEEG backgrounds were assessed. RESULTS: The positive predictive value of an abnormal aEEG pattern at the age of 3 to 6 hours was 84% for normothermia and 59% for hypothermia. Moderate abnormal voltage background at 3 to 6 hours of age did not predict outcome. The recovery time to normal background pattern was the best predictor of poor outcome (96.2% in hypothermia, 90.9% in normothermia). Never developing SWC always predicted poor outcome. Time to SWC was a better outcome predictor for infants who were treated with hypothermia (88.5%) than with normothermia (63.6%). CONCLUSIONS: Early aEEG patterns can be used to predict outcome for infants treated with normothermia but not hypothermia. Infants with good outcome had normalized background pattern by 24 hours when treated with normothermia and by 48 hours when treated with hypothermia.
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Citations
Cites
Principles and Practice of Sleep Medicine
(2011) · Elsevier eBooks · doi:10.1016/c2009-0-59875-3 · Cited by 5,088
Neonatal Encephalopathy Following Fetal Distress: A Clinical and Electroencephalographic Study
Sarnat, H. B. (1976) · Archives of Neurology · doi:10.1001/archneur.1976.00500100030012 · Cited by 2,680
Gluckman, P. D., Wyatt, J. S., Azzopardi, D., Ballard, R., Edwards, A. D., Ferriero, D. M., Polin, R. A., Robertson, C. M., Thoresen, M., Whitelaw, A., et al. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17946-x · Cited by 2,270
Self-citationModerate Hypothermia to Treat Perinatal Asphyxial Encephalopathy
Azzopardi, D. V., Strohm, B., Edwards, A. D., Dyet, L., Halliday, H. L., Juszczak, E., Kapellou, O., Levene, M., Marlow, N., Porter, E., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0900854 · Cited by 1,710
Self-citationPrinciples and Practice of Sleep Medicine
Stafford, R. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.8.1074 · Cited by 614
Rutherford, M., Ramenghi, L. A., Edwards, A. D., Brocklehurst, P., Halliday, H., Levene, M., Strohm, B., Thoresen, M., Whitelaw, A., & Azzopardi, D. (2010) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70295-9 · Cited by 600
Self-citationAssessment of Neonatal Encephalopathy by Amplitude-integrated Electroencephalography
al Naqeeb, N., Edwards, A. D., Cowan, F. M., & Azzopardi, D. (1999) · Pediatrics · doi:10.1542/peds.103.6.1263 · Cited by 458
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Self-citationThoresen, M., & Whitelaw, A. (2000) · Pediatrics · doi:10.1542/peds.106.1.92 · Cited by 321
Self-citationShalak, L. F., Laptook, A. R., Velaphi, S. C., & Perlman, J. M. (2003) · Pediatrics · doi:10.1542/peds.111.2.351 · Cited by 249
Cited by
Cooling for newborns with hypoxic ischaemic encephalopathy
Jacobs, S. E., Berg, M., Hunt, R., Tarnow-Mordi, W. O., Inder, T. E., & Davis, P. G. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003311.pub3 · Cited by 2,328
Hypoxic-Ischemic Encephalopathy: A Review for the Clinician
Douglas-Escobar, M., & Weiss, M. D. (2015) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2014.3269 · Cited by 778
Prognostic Tests in Term Neonates With Hypoxic-Ischemic Encephalopathy: A Systematic Review
van Laerhoven, H., de Haan, T. R., Offringa, M., Post, B., & van der Lee, J. H. (2013) · Pediatrics · doi:10.1542/peds.2012-1297 · Cited by 257
Sleep Disturbances in Newborns
Barbeau, D. Y., & Weiss, M. D. (2017) · Children · doi:10.3390/children4100090 · Cited by 84
Martini, S., Austin, T., Aceti, A., Faldella, G., & Corvaglia, L. (2020) · Pediatric Research · doi:10.1038/s41390-019-0639-6 · Cited by 50
Metadata
- Authors
- Thoresen, M., Hellström-Westas, L., Liu, X., & de Vries, L. S.
- Venue
- Pediatrics
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2010-07-01
- Volume
- 126
- Issue
- 1
- Pages
- e131-e139
- ISSN
- 0031-4005 (ISSN-L)
- 1098-4275
- OpenAlex
- W2147316690
- Cited by
- 438
- References
- 28
- FWCI
- 23.35
- Type
- journal article
- Language
- en
- Open access
- closed
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