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Cited by 459

The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.

Management of Neonates Born at ≥35 0/7 Weeks’ Gestation With Suspected or Proven Early-Onset Bacterial Sepsis

Puopolo, Karen M., Benitz, William E., Zaoutis, Theoklis E., COMMITTEE ON FETUS AND NEWBORN, COMMITTEE ON INFECTIOUS DISEASES, Cummings, James, Juul, Sandra, Hand, Ivan, Eichenwald, Eric, Poindexter, Brenda, Stewart, Dan L., Aucott, Susan W., Goldsmith, Jay P., Watterberg, Kristi, Byington, Carrie L., Maldonado, Yvonne A., Banerjee, Ritu, Barnett, Elizabeth D., Campbell, James D., Gerber, Jeffrey S., Lynfield, Ruth, Munoz, Flor M., Nolt, Dawn, Nyquist, Ann-Christine, O’Leary, Sean T., Rathore, Mobeen H., Sawyer, Mark H., Steinbach, William J., Tan, Tina Q.·2018·Pediatrics

Abstract

The incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last 2 decades, primarily because of the implementation of evidence-based intrapartum antimicrobial therapy. However, EOS remains a serious and potentially fatal illness. Laboratory tests alone are neither sensitive nor specific enough to guide EOS management decisions. Maternal and infant clinical characteristics can help identify newborn infants who are at risk and guide the administration of empirical antibiotic therapy. The incidence of EOS, the prevalence and implications of established risk factors, the predictive value of commonly used laboratory tests, and the uncertainties in the risk/benefit balance of antibiotic exposures all vary significantly with gestational age at birth. Our purpose in this clinical report is to provide a summary of the current epidemiology of neonatal sepsis among infants born at ≥35 0/7 weeks’ gestation and a framework for the development of evidence-based approaches to sepsis risk assessment among these infants.

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Metadata

Authors
Puopolo, K. M., Benitz, W. E., Zaoutis, T. E., COMMITTEE ON FETUS AND NEWBORN, COMMITTEE ON INFECTIOUS DISEASES, Cummings, J., Juul, S., Hand, I., Eichenwald, E., Poindexter, B., Stewart, D. L., Aucott, S. W., Goldsmith, J. P., Watterberg, K., Byington, C. L., Maldonado, Y. A., Banerjee, R., Barnett, E. D., Campbell, J. D., Gerber, J. S., Lynfield, R., Munoz, F. M., Nolt, D., Nyquist, A.-C., O’Leary, S. T., Rathore, M. H., Sawyer, M. H., Steinbach, W. J., & Tan, T. Q.
Venue
Pediatrics
Published
2018-12-01
Volume
142
Issue
6
ISSN
  • 0031-4005 (ISSN-L)
  • 1098-4275
OpenAlex
W2917503776
Cited by
459
References
63
FWCI
34.80
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Management of Neonates Born at ≥35 0/7 Weeks’ Gestation With Suspected or Proven Early-Onset Bacterial Sepsis. https://app.cochat.ai/papers/10.1542/peds.2018-2894
The paper
Puopolo, K. M., Benitz, W. E., Zaoutis, T. E., COMMITTEE ON FETUS AND NEWBORN, COMMITTEE ON INFECTIOUS DISEASES, Cummings, J., Juul, S., Hand, I., Eichenwald, E., Poindexter, B., Stewart, D. L., Aucott, S. W., Goldsmith, J. P., Watterberg, K., Byington, C. L., Maldonado, Y. A., Banerjee, R., Barnett, E. D., Campbell, J. D., . . . Tan, T. Q. (2018). Management of Neonates Born at ≥35 0/7 Weeks’ Gestation With Suspected or Proven Early-Onset Bacterial Sepsis. Pediatrics. https://doi.org/10.1542/peds.2018-2894

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.