Hyperlipidemia
Abstract
Cardiovascular disease remains the top cause of morbidity and mortality in the United States. Atherosclerotic plaques are known to start in adolescence, and, therefore, young adults can be affected by coronary artery disease. Children with known risk factors, such as genetic predisposition, including familial hyperlipidemias, diabetes, and renal diseases, are at higher risk. With childhood obesity becoming an epidemic in certain parts of the United States, this problem is further highlighted as an important issue affecting children's health. There are unclear recommendations for pediatricians regarding cholesterol screening of pediatric populations, when to initiate hyperlipidemia treatment with statin therapy, and when to refer to a specialist for further management. This article reviews the epidemiology and pathophysiology of hyperlipidemia, recommendations for screening and types of screening, management (including pharmacology), prognosis, and prevention.
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Hyperlipidemia is a significant risk factor for the onset of cardiovascular diseases.
“Hyperlipidemia constitutes a significant risk factor in the onset of cardiovascular diseases (Stewart et al., 2020).”
From Lactiplantibacillus plantarum N4 ameliorates lipid metabolism and gut microbiota structure in high fat diet-fed rats (2024) · cites this paper as Stewart et al., 2020
Cites
Kavey, R., Simons-Morton, D., & de Jesus, J. D. (2011) · Pediatrics · doi:10.1542/peds.2009-2107c · Cited by 2,131 · see citing works
Ishibashi, S., Brown, M. S., Goldstein, J. L., Gerard, R. D., Hammer, R. E., & Herz, J. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116663 · Cited by 1,612 · see citing works
McGill, H. C., McMahan, C. A., Zieske, A. W., Sloop, G. D., Walcott, J. V., Troxclair, D. A., Malcom, G. T., Tracy, R. E., Oalmann, M. C., & Strong, J. P. (2000) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.20.8.1998 · Cited by 421 · see citing works
Child–Parent Familial Hypercholesterolemia Screening in Primary Care
Wald, D. S., Bestwick, J. P., Morris, J. K., Whyte, K., Jenkins, L., & Wald, N. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1602777 · Cited by 320 · see citing works
Statins for children with familial hypercholesterolemia
Vuorio, A. F., Kuoppala, J., Kovanen, P. T., Humphries, S. E., Tonstad, S., Wiegman, A., Drogari, E., & Ramaswami, U. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006401.pub4 · Cited by 264 · see citing works
Distribution of Lipoproteins by Age and Gender in Adolescents
Jolliffe, C. J., & Janssen, I. (2006) · Circulation · doi:10.1161/circulationaha.106.620864 · Cited by 211 · see citing works
Screening for Lipid Disorders in Children and Adolescents
US Preventive Services Task Force, Bibbins-Domingo, K. B., Grossman, D. C., Curry, S. J., Davidson, K. W., Epling, J. W., García, F., Gillman, M. W., Kemper, A. R., Krist, A. H., et al. (2016) · JAMA · doi:10.1001/jama.2016.9852 · Cited by 174 · see citing works
THE FAMILIAL CHYLOMICRONEMIA SYNDROME
Santamarina-Fojo, S. (1998) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70025-6 · Cited by 162 · see citing works
Primary hypertriglyceridemia in children and adolescents
SHAH, A. S., & Wilson, D. P. (2015) · Journal of clinical lipidology · doi:10.1016/j.jacl.2015.04.004 · Cited by 89 · see citing works
Guidance for Pediatric Familial Hypercholesterolemia 2017
Harada‐Shiba, M., Ohta, T., Ohtake, A., Ogura, M., Dobashi, K., Nohara, A., Yamashita, S., Yokote, K., & Joint Working Group by Japan Pediatric Society and Japan Atherosclerosis Society for Making Guidance of Pediatric Familial Hypercholesterolemia (2018) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.cr002 · Cited by 88 · see citing works
Marais, A. D., Solomon, G. A. E., & Blom, D. J. (2014) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408363.2013.870526 · Cited by 70 · see citing works
Approach to Hypertriglyceridemia in the Pediatric Population
Valaiyapathi, B., Sunil, B., & Ashraf, A. P. (2017) · Pediatrics in Review · doi:10.1542/pir.2016-0138 · Cited by 66 · see citing works
Zappalla, F. R., & Gidding, S. S. (2009) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2008.11.006 · Cited by 37 · see citing works
Secondary hypertriglyceridemia in children and adolescents
Blackett, P. R., Wilson, D. P., & McNeal, C. J. (2015) · Journal of clinical lipidology · doi:10.1016/j.jacl.2015.04.006 · Cited by 35 · see citing works
Universal Cholesterol Screening in Childhood: A Systematic Review
Smith, A. J. B., Turner, E. L., & Kinra, S. (2016) · Academic Pediatrics · doi:10.1016/j.acap.2016.06.005 · Cited by 35 · see citing works
Treatment of dyslipidemia in children and adolescents
Holmes, K. W., & Kwiterovich, P. O. (2005) · Current Cardiology Reports · doi:10.1007/s11886-005-0063-x · Cited by 33 · see citing works
Biochemistry; Lippincott's illustrated reviews
(1988) · International Journal of Biochemistry · doi:10.1016/s0020-711x(98)90024-6 · Cited by 26 · see citing works
Harada‐Shiba, M., Kastelein, J. J. P., Hovingh, G. K., Ray, K. K., Ohtake, A., Arisaka, O., Ohta, T., Okada, T., Suganami, H., & Wiegman, A. (2017) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.42242 · Cited by 25 · see citing works
The safety of statins in children
Lamaida, N., Capuano, E., Pinto, L., Capuano, E., Capuano, R., & Capuano, V. (2013) · Acta Paediatrica · doi:10.1111/apa.12280 · Cited by 24 · see citing works
Genetic disorders of lipoprotein transport in children
Clauss, S. B., & Kwiterovich, P. O. (2003) · Progress in Pediatric Cardiology · doi:10.1016/s1058-9813(03)00049-3 · Cited by 21 · see citing works
What Should Be the Screening Strategy for Familial Hypercholesterolemia?
McCrindle, B. W., & Gidding, S. S. (2016) · New England Journal of Medicine · doi:10.1056/nejme1611081 · Cited by 20 · see citing works
Hyperlipidaemia in Paediatric Patients
Wierzbicki, A. S., & Viljoen, A. (2010) · Drug Safety · doi:10.2165/11319490-000000000-00000 · Cited by 19 · see citing works
Hospital Management of Severe Hypertriglyceridemia in Children
Valaiyapathi, B., & Ashraf, A. P. (2018) · Current Pediatric Reviews · doi:10.2174/1573400514666180117092707 · Cited by 18 · see citing works
Management of hyperlipidemia in pediatrics
Daniels, S. R. (2012) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e32834fea6c · Cited by 17 · see citing works
Management of hyperlipidemia in the pediatric population
Tonstad, S., & Thompson, G. R. (2004) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-004-0027-2 · Cited by 14 · see citing works
Statins in the Management of Pediatric Dyslipidemia
Ross, J. L. (2016) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2016.07.004 · Cited by 14 · see citing works
Why Cholesterol Testing in Children and Adolescents Matters
Gidding, S. S. (2016) · JAMA Cardiology · doi:10.1001/jamacardio.2016.2871 · Cited by 12 · see citing works
Stempel, H., Dodge, A., Marriott, E., & Peterson, A. L. H. (2016) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2016.08.016 · Cited by 12 · see citing works
Management of familial hypercholesterolaemia in children and adolescents
Justo, R. N. (2011) · Journal of Paediatrics and Child Health · doi:10.1111/j.1440-1754.2011.02206.x · Cited by 11 · see citing works
Update on pediatric hyperlipidemia
Chauhan, A., & Paunikar, P. (2014) · Current Opinion in Pediatrics · doi:10.1097/mop.0000000000000078 · Cited by 11 · see citing works
Type V hypertriglyceridemia in children, a therapeutic challenge in pediatrics
Mărginean, C. O., Meliţ, L. E., Dobreanu, M., & Săsăran, M. O. (2017) · Medicine · doi:10.1097/md.0000000000008864 · Cited by 10 · see citing works
A 10-year experience using combined lipid-lowering pharmacotherapy in children and adolescents
Araujo, M. B., & Pacce, M. S. (2016) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2016-0117 · Cited by 9 · see citing works
Treatment Strategies for Hypercholesterolemia
Hartz, J., & Clauss, S. B. (2018) · Current Pediatric Reviews · doi:10.2174/1573396314666180111143900 · Cited by 6 · see citing works
Newman, T. B., Schroeder, A. R., & Pletcher, M. J. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2016.5114 · Cited by 5 · see citing works
Kosmeri, C., Siomou, E. C., Vlahos, A. P., & Milionis, H. J. (2018) · Acta Paediatrica · doi:10.1111/apa.14529 · Cited by 5 · see citing works
Hyperlipidemia treatment in children: the younger, the better.
Gauer, R. L. (2010) · PubMed · Cited by 4 · see citing works
Cholesterol screening for kids sparks debate (again)
Couzin-Frankel, J. (2016) · Science · doi:10.1126/science.353.6302.855 · Cited by 1 · see citing works
Screening children at immunisation visits can identify familial hypercholesterolaemia
Mayor, S. (2016) · BMJ · doi:10.1136/bmj.i5794 · Cited by 1 · see citing works
Flagged first, then by citations
2 of the 40 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Obesity and Cardiometabolic Risk Factors: From Childhood to Adulthood
Drożdż, D., Pitti, J. Á., Wójcik, M., Borghi, C., Gabbianelli, R., Mazur, A., Herceg-Čavrak, V., López‐Valcárcel, B. G., Brzeziński, M., Lurbe, E., et al. (2021) · Nutrients · doi:10.3390/nu13114176 · Cited by 441 · see citing works
Qiu, Y.-Y., Zhang, J., Zeng, F.-Y., & Zhu, Y. Z. (2023) · Pharmacological Research · doi:10.1016/j.phrs.2023.106786 · Cited by 271 · see citing works
Wang, W., Tan, J., Nima, L., Sang, Y., Cai, X. D., & Xue, H. (2022) · Food Chemistry X · doi:10.1016/j.fochx.2022.100414 · Cited by 161 · see citing works
Iron, ferroptosis, and ischemic stroke
Guo, J., Tuo, Q., & Lei, P. (2023) · Journal of Neurochemistry · doi:10.1111/jnc.15807 · Cited by 162 · see citing works
Huang, Y., Sulek, K., Stinson, S. E., Holm, L. A., Kim, M. G., Trôst, K., Hooshmand, K., Lund, M. A. V., Fonvig, C. E., Juel, H. B., et al. (2024) · Nature Medicine · doi:10.1038/s41591-024-03279-x · Cited by 76 · see citing works
Dyslipidemia Diagnosis and Treatment: Risk Stratification in Children and Adolescents
Mosca, S. M. F. S., Araújo, G., Costa, V. F. D. A., Correia, J., Bandeira, A., Martins, E., Mansilha, H. F., Tavares, M., & Coelho, M. P. (2022) · Journal of Nutrition and Metabolism · doi:10.1155/2022/4782344 · Cited by 71 · see citing works
Palabıyık, E., Sulumer, A. N., Uğuz, H., Avcı, B., Aşkın, S., Aşkın, H., & Demir, Y. (2022) · Journal of Molecular Recognition · doi:10.1002/jmr.3004 · Cited by 68 · see citing works
Hyperlipidemia and Cardiovascular Risk in Children and Adolescents
Mainieri, F., Bella, S. L., & Chiarelli, F. (2023) · Biomedicines · doi:10.3390/biomedicines11030809 · Cited by 61 · see citing works
Role of ABCA1 in Cardiovascular Disease
Wang, J., Xiao, Q., Wang, L., Wang, Y., Wang, D. W., & Ding, H. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12061010 · Cited by 59 · see citing works
Insights into the pivotal role of statins and its nanoformulations in hyperlipidemia
Singh, S., Zahoor, I., Sharma, N., Behl, T., Kanojia, N., Sehgal, A., Mohan, S., Almoshari, Y., Salawi, A., Aleya, L., et al. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-23043-3 · Cited by 54 · see citing works
Tufail, T., Ain, H. B. U., Chen, J., Virk, M. S., Ahmed, Z., Ashraf, J., Shahid, N. U. A., & Xu, B. (2024) · Foods · doi:10.3390/foods13091305 · Cited by 49 · see citing works
Chen, Y., Chen, X., Yang, X., Gao, P., Yue, C., Wang, L., Wu, T., Jiang, T., Wu, H., Wang, Z., et al. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116199 · Cited by 46 · see citing works
Treatment of Dyslipidaemia in Children
Fiorentino, R., & Chiarelli, F. (2021) · Biomedicines · doi:10.3390/biomedicines9091078 · Cited by 45 · see citing works
Cohen, H., Stefanutti, C., Giacomo, S. D., Morozzi, C., Widhalm, K., Bjelakovic, B. B., Berni, A., Martino, F., & Bosco, G. (2021) · Current Atherosclerosis Reports · doi:10.1007/s11883-021-00926-3 · Cited by 41 · see citing works
Zhao, C., Qu, Q., Fang, Y., Li, Z., Yang, P., Han, L., & Shi, X. (2021) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2021.114300 · Cited by 40 · see citing works
Wang, T., Liu, L., Deng, J., Jiang, Y., Yan, X., & Liu, W. (2023) · Food & Function · doi:10.1039/d2fo03509j · Cited by 39 · see citing works
Wang, Y.-H., Chen, X., Bai, Y.-Z., Gao, P., Yang, Z. R., Guo, Q., Lu, Y., Zheng, J., Liu, D., Yang, J., et al. (2024) · Theranostics · doi:10.7150/thno.89602 · Cited by 39 · see citing works
Lv, Y., Zou, Y., Zhang, X., Liu, B., Peng, X. X., & Chu, C. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1071276 · Cited by 37 · see citing works
Zhou, Y.-F., Nie, J., Shi, C., Zheng, W.-W., Ning, K., Kang, J., Sun, J.-X., Cong, X., Xie, Q., & Xiang, H. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.125725 · Cited by 37 · see citing works
Wiciński, M., Fajkiel-Madajczyk, A., Kurant, Z., Liss, S., Szyperski, P., Szambelan, M., Gromadzki, B., Rupniak, I., Słupski, M., & Sadowska-Krawczenko, I. (2024) · Nutrients · doi:10.3390/nu16152481 · Cited by 44 · see citing works
Research Progress on bioactive peptides from animal sources: A comprehensive review.
Sun, J., Chen, Y.-L., Yang, Y., Chen, H., Zhang, J., Wang, S.-P., Bai, D.-M., Sun, Z., Song, J., & Dai, L. (2025) · Food Chemistry · doi:10.1016/j.foodchem.2025.145006 · Cited by 30 · see citing works
Oliveira, L. S. D., & Ritter, M. (2024) · Hepatology Communications · doi:10.1097/hc9.0000000000000596 · Cited by 32 · see citing works
Zexie Tang targeting FKBP38/mTOR/SREBPs pathway improves hyperlipidemia
Xie, Z., Li, E.-W., Gao, G., Yue-Yue, D. U., Wang, M., Wang, H., Wang, P., Qiao, Y., Su, Y., Xu, J., et al. (2022) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2022.115101 · Cited by 31 · see citing works
Song, Y., Cai, Q., Wang, S., Li, L., Wang, Y., Zou, S., Gao, X., & Wei, Y. (2022) · Nutrients · doi:10.3390/nu14235066 · Cited by 29 · see citing works
Wang, Z.-R., Kong, L.-J., Zhang, H., Sun, F.-J., Guo, Z., Zhang, R., & Dou, Y.-L. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.811719 · Cited by 25 · see citing works
Ionizable drug delivery systems for efficient and selective gene therapy
Zhang, Y., Guo, R., Chen, Y., Li, T., Du, W.-Z., Xiang, R., Guan, J., Li, Y., Huang, Y., Yu, Z., et al. (2023) · Military Medical Research · doi:10.1186/s40779-023-00445-z · Cited by 27 · see citing works
Zheng, L., Lü, Z., Ma, Y., Cui, P., Zhang, X., Gan, J., & Li, G. (2025) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.14188 · Cited by 23 · see citing works
Zhao, G., Gao, M., Guo, S., Zeng, S., Ye, C., Wang, M., Anwar, Z., Hu, B., & Hong, Y. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.164073 · Cited by 22 · see citing works
Actinidia arguta (Sieb. et Zucc.) Planch. ex Miq.: A Review of Phytochemistry and Pharmacology
Zhang, H., Teng, K., & Zang, H. (2023) · Molecules · doi:10.3390/molecules28237820 · Cited by 22 · see citing works
Atty, S. A., Abdel‐Raoof, A. M., Fouad, F. A., Mohamed, T. F., & Elbardisy, H. M. (2023) · Sustainable Chemistry and Pharmacy · doi:10.1016/j.scp.2023.101300 · Cited by 21 · see citing works
Zhang, Z., Diao, P., Zhang, X., Nakajima, T., Kimura, T., & Tanaka, N. (2022) · Biomedicines · doi:10.3390/biomedicines10071667 · Cited by 20 · see citing works
Xu, W., Li, J., Chen, J., Xu, J., Zheng, D., Wu, M., Mu, Y., Huang, X., & Li, L. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.133668 · Cited by 20 · see citing works
Zhang, Y., Guo, Z., Wang, J., Yue, Y., Yang, Y., Wen, Y., Luo, Y., & Zhang, X. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116856 · Cited by 20 · see citing works
Feng, X., Ding, L., Ma, G., Zhang, Y., Sun, Y., Li, Z., Tao, X., Ali, A. M. M., Wang, D., & Wu, L. (2022) · Molecules · doi:10.3390/molecules27217357 · Cited by 19 · see citing works
Bell, A. S., Rosoff, D. B., Mavromatis, L. A., Jung, J., Wagner, J., & Lohoff, F. W. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.122.026122 · Cited by 18 · see citing works
Cui, N., Zhang, W., Su, F., Zhang, Z., Qiao, W., Sun, Y., Yang, B., Kuang, H., & Wang, Q. (2023) · Molecules · doi:10.3390/molecules28176352 · Cited by 18 · see citing works
He, K., Gao, Q., Su, J., Shang, H., Meng, X., Jiang, S., Liu, D., & Huang, B. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c00108 · Cited by 18 · see citing works
Cheng, F., Tsai, K., Huang, K., Kung, C., Huang, W., You, H., Li, S.-H., Wang, C., Lee, W., & Pan, H.-Y. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1340261 · Cited by 18 · see citing works
Xie, J. W., Luo, M., Chen, Q., Zhang, Q., Qin, L., Wang, Y., Zhao, Y., & He, Y. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118066 · Cited by 18 · see citing works
Clarke, K. E. N., Kim, Y., Jones, J. M., Lee, A., Deng, Y., Nycz, E., Iachan, R., Gundlapalli, A. V., MacNeil, A., & Hall, A. J. (2022) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiac423 · Cited by 17 · see citing works
Barabadi, H., Soltani, M., Noqani, H., Kashani, A. S., Nasiri, M., Karami, K., Vahidi, H., & Saravanan, M. (2024) · Results in Surfaces and Interfaces · doi:10.1016/j.rsurfi.2024.100264 · Cited by 16 · see citing works
Deng, M., Zhang, S., Wu, S., Jiang, Q., Teng, W., Luo, T., Ouyang, Y., Liu, J., & Gu, B. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1390293 · Cited by 15 · see citing works
Zhao, J., Li, N., Li, S., & Dou, J. (2025) · Cardiovascular Diabetology · doi:10.1186/s12933-025-02783-9 · Cited by 15 · see citing works
Mellin, J., Prevost, M. L., Kenny, J. M., Sturgeon, K., Thompson, L. C., Foster, C., Kessler, H. H., Goswami, N., Klein, N. J., Judd, A., et al. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.821568 · Cited by 15 · see citing works
Shafique, H., Rehman, A., Nawaz, H., Majeed, M. I., Alshammari, A., Albekairi, N. A., Ali, A., Shahzadi, A., Yaseen, S., Sabah, N. U., et al. (2025) · Plasmonics · doi:10.1007/s11468-025-02785-z · Cited by 14 · see citing works
Garg, A., & Radhakrishnan, S. (2024) · Indian Heart Journal · doi:10.1016/j.ihj.2023.11.269 · Cited by 14 · see citing works
Alwahsh, M., Alejel, R., Hasan, A., Abuzaid, H., & Al‐Qirim, T. M. (2024) · Metabolites · doi:10.3390/metabo14080438 · Cited by 14 · see citing works
Xia, K.-R., Zhang, X., Zhang, H.-Q., Su, K., Shang, E., Xiao, Q.-L., Li, W., Guo, S., Duan, J., & Liu, P. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118158 · Cited by 13 · see citing works
Shang, L.-Y., Zhang, S., Zhang, M., Sun, X.-D., Wang, Q., Liu, Y., Zhao, Y., Zhao, M. Y., Wang, P., & Gao, X. (2024) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105968 · Cited by 12 · see citing works
Association between pan-immune-inflammation value and dyslipidemia in the United States population
Yan, Y., Jia, S., Huo, X., Liu, L., Sun, L., Ma, S., & Chen, X. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1518304 · Cited by 12 · see citing works
Wang, Y., Zhang, J., Tian, T., Gao, M.-Y., Zhu, Q., Xie, W., Fu, L., Wang, S., & Dai, Y. (2021) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.09.004 · Cited by 12 · see citing works
Circadian Blood Pressure Profile in Pediatric Patients with Primary Hypertension
Szyszka, M., Skrzypczyk, P., Ofiara, A., Wabik, A. M., Pietrzak, R., Werner, B., & Pańczyk-Tomaszewska, M. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11185325 · Cited by 11 · see citing works
Fucoxanthin improves serum lipids, liver metabolism and gut microbiota in hyperlipidemia mice
Zhou, Y., Zhang, J., Xu, K., Zhang, W., Chen, F., Liu, B., & Guo, B. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2024.9250017 · Cited by 11 · see citing works
Xu, C., Zhang, M., Zhang, S., Wang, P., Lai, C., Meng, D., Chen, Z., Yi, X., & Gao, X. (2024) · Journal of Chromatography B · doi:10.1016/j.jchromb.2024.124210 · Cited by 12 · see citing works
Li, J., Guo, M., Yuan, C., Li, T., Zhang, J., & Ren, L. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105582 · Cited by 11 · see citing works
Research progress of cysteine transporter SLC7A11 in endocrine and metabolic diseases
Chen, J., Yuan, M., & Wang, J. (2025) · Molecular Biology Reports · doi:10.1007/s11033-024-10193-5 · Cited by 11 · see citing works
Tiwari, A., Shukla, A., & Samal, P. K. (2025) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.70255 · Cited by 11 · see citing works
Research advances in the influence of lipid metabolism on cognitive impairment
Zhang, M., Zhu, Y., & Zhu, Z. (2022) · Ibrain · doi:10.1002/ibra.12018 · Cited by 11 · see citing works
Rutkowska, L., Sałacińska, K., Salachna, D., Matusik, P., Pinkier, I., Kępczyński, Ł., Piotrowicz, M., Starostecka, E., Lewiñski, A., & Gach, A. (2022) · Genes · doi:10.3390/genes13060999 · Cited by 11 · see citing works
Shabbir, R., Malik, M. N. H., Zaib, M., Alamgeer, Jahan, S., & Khan, M. T. (2022) · ACS Omega · doi:10.1021/acsomega.2c05735 · Cited by 11 · see citing works
Nutraceutical properties, biological activities, and industrial applications of chickpea protein
Akram, S., Afzal, M. F., Anwer, K., Farman, L., Zubaır, M., Kousar, S., Iqbal, T., Khalid, W., Elawad, M. A., Ahmed, A., et al. (2024) · Cogent Food & Agriculture · doi:10.1080/23311932.2024.2338653 · Cited by 11 · see citing works
Prommaouan, S., Nernpermpisooth, N., Pengnet, S., Paseephol, T., Tunsophon, S., & Malakul, W. (2022) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2022.08.002 · Cited by 10 · see citing works
Luo, S., Lam, H. S., Chan, Y. H., Tang, C. S.-M., He, B., Kwok, M. K., Leung, G. M., Schooling, C. M., & Yeung, S. L. A. (2023) · BMC Medicine · doi:10.1186/s12916-023-03115-y · Cited by 10 · see citing works
Frequency of Dyslipidemia and Associated Risk Factors Among Obese Children and Adolescents in Turkey
Dündar, İ., & Akıncı, A. (2022) · Iranian Journal of Pediatrics · doi:10.5812/ijp-122937 · Cited by 10 · see citing works
Wang, Q., Li, Y., Ren, H., Huang, Q., Wang, X., Zhou, Y., Wu, Q., Liu, Y., Li, M., Wang, Y., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.12.096 · Cited by 10 · see citing works
Jeong, H. C., Cha, G. S., Yun, C., & Park, C. M. (2024) · Process Biochemistry · doi:10.1016/j.procbio.2024.01.004 · Cited by 9 · see citing works
Sun, J., Du, B., Chen, M., Jia, J., Wang, X., & Hong, J. E. (2024) · Journal of Endocrinological Investigation · doi:10.1007/s40618-024-02376-5 · Cited by 9 · see citing works
Liu, W. D., & Lu, P. (2024) · Interdisciplinary Sciences Computational Life Sciences · doi:10.1007/s12539-024-00645-8 · Cited by 9 · see citing works
Anguera-Tejedor, M., Garrido, G., Garrido‐Suárez, B. B., Ardiles, A., Bistué‐Rovira, À., Jiménez‐Altayó, F., & Delgado, R. (2024) · Food Bioscience · doi:10.1016/j.fbio.2024.105487 · Cited by 10 · see citing works
Geng, X., Tian, W., Zhuang, M., Ma, W., Lin, R., Shang, H., Yu, Z., Shen, R., & Li, J. (2024) · Foods · doi:10.3390/foods13244113 · Cited by 9 · see citing works
Zhao, L., Wang, S., Xu, X., Guo, W., Yang, J., Liu, Y., Xie, S., Piao, G., Xu, T., Wang, Y., et al. (2023) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.13213 · Cited by 9 · see citing works
Jia, Y., Zhang, Q., Zhang, Y., Wang, H., Niu, Q., Zhu, R., Li, J., Fan, W., & Zhang, Y. (2024) · Journal of Multidisciplinary Healthcare · doi:10.2147/jmdh.s471372 · Cited by 8 · see citing works
Shen, Z., Gao, X., Huang, D., Xu, X., & Shen, J. (2024) · Food Science & Nutrition · doi:10.1002/fsn3.4250 · Cited by 8 · see citing works
Jawaria, Zarlashat, Y., Philippovich, M., & Dósa, E. (2025) · Biomolecules · doi:10.3390/biom15091281 · Cited by 8 · see citing works
Pediatric Dyslipidemia and Screening Recommendations
Buterbaugh, J. S. (2021) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2021.08.009 · Cited by 8 · see citing works
Al-Bayati, M., Issa, R. A., Abu‐Samak, M., Alnsour, L., & Awwad, S. H. (2023) · Pharmacia · doi:10.3897/pharmacia.70.e101623 · Cited by 8 · see citing works
Kubi, S. A., Amponsah, I. K., Turkson, B. K., Asante-Kwatia, E., Nkrumah, D., & Dickson, R. A. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e24352 · Cited by 8 · see citing works
Integrating genomics and precision health knowledge into practice: A guide for nurse practitioners
Walker, T. K., Ersig, A. L., Dwyer, A. A., Kronk, R. A., Snyder, C. T., Whitt, K. J., & Willis, V. (2024) · Journal of the American Association of Nurse Practitioners · doi:10.1097/jxx.0000000000001050 · Cited by 8 · see citing works
Ashari, S., Jamialahmadi, T., Davies, N. M., Almahmeed, W. A., & Sahebkar, A. (2024) · Drug and Chemical Toxicology · doi:10.1080/01480545.2024.2405830 · Cited by 8 · see citing works
Aissatou, Aboubakar, Hamadou, M., & Abdoulaye, M. (2025) · Food Chemistry Advances · doi:10.1016/j.focha.2025.101089 · Cited by 8 · see citing works
Wang, C., Pang, W., Du, X., Zhai, J.-N., Zhong, M., Zhuang, M., An, J., Cao, L., Zhang, L., Zheng, W., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.974995 · Cited by 8 · see citing works
Pan, Q.-C., Li, B., & Zou, K. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1595887 · Cited by 7 · see citing works
Wei, L., Wu, H., Li, W., Chen, M., Cui, B., Wang, X., Wu, T., & Cheng, Y. (2025) · Food & Function · doi:10.1039/d5fo01536g · Cited by 7 · see citing works
Anti-Hyperlipidemic Components of the Leaves of Synsepalum dulcificum (Miracle Fruit)
Xie, J., Chen, X., Tan, Y., Li, W., Yin, C., Zhong, T., Su, D. T., Sun, J., Tian, H., & Huang, W. (2024) · Plant Foods for Human Nutrition · doi:10.1007/s11130-024-01152-3 · Cited by 7 · see citing works
Acharya, B., Behera, A., Sahu, P. K., Chowdhury, B., & Behera, S. (2024) · Advances in Bamboo Science · doi:10.1016/j.bamboo.2024.100074 · Cited by 7 · see citing works
NT-proBNP as a Potential Marker of Cardiovascular Damage in Children with Chronic Kidney Disease
Skrzypczyk, P., Okarska‐Napierała, M., Pietrzak, R., Pawlik, K. K., Waścińska, K., Werner, B., & Pańczyk-Tomaszewska, M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10194344 · Cited by 7 · see citing works
Early Vascular Aging in Children With Tuberous Sclerosis Complex
Skrzypczyk, P., Wabik, A. M., Szyszka, M., Jóźwiak, S., Bombiński, P., Jakimów-Kostrzewa, A., Brzewski, M., & Pańczyk-Tomaszewska, M. (2021) · Frontiers in Pediatrics · doi:10.3389/fped.2021.767394 · Cited by 7 · see citing works
Significance of stressor media on the stability of statins: a critical assessment
Lalchandani, D. S., Chenkual, L., Mahindran, M., & Porwal, P. K. (2022) · Chemical Papers · doi:10.1007/s11696-022-02306-w · Cited by 7 · see citing works
Han, S., Wu, X., Zhu, L., Lu, H., Ling, X., Luo, Y., Hu, Z., Zhou, Y., Tang, Y., & Luo, F. (2023) · Food & Function · doi:10.1039/d3fo03288d · Cited by 7 · see citing works
Clarke, K. E. N., Kim, Y., Jones, J., Lee, A., Deng, Y., Nycz, E., Iachan, R., Gundlapalli, A. V., MacNeil, A., & Hall, A. J. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4092074 · Cited by 7 · see citing works
Isolation and bioactivities of nomilin from citrus family: a review
Li, W., Wang, N., Liu, J., Ma, Y., Wang, Q., Li, W., Mu, Y., Wu, Q., & Wang, C. (2025) · Journal of Future Foods · doi:10.1016/j.jfutfo.2024.11.018 · Cited by 6 · see citing works
Kumari, D., & Syed, S. M. (2025) · BioNanoScience · doi:10.1007/s12668-025-02207-8 · Cited by 6 · see citing works
Yang, B., Lian, L., Xing, K., Cen, Y., Zhao, Y., & Zhang, Y. (2025) · Nutrients · doi:10.3390/nu17193155 · Cited by 6 · see citing works
Diagnosis and Management of Congenital Coronary Artery Fistulas in Infants and Children
Wu, S. J., Fares, M., Zellers, T. M., Jyothinagaram, M., & Reddy, S. V. (2023) · Current Cardiology Reports · doi:10.1007/s11886-023-02007-0 · Cited by 6 · see citing works
Chen, W., Zhang, Y., Miao, G., Ying, Y., Ren, Z., Sun, X., Cai, J., Shen, H., & Lu, H. (2024) · Medical Gas Research · doi:10.4103/mgr.medgasres-d-23-00047 · Cited by 6 · see citing works
Effects of school‐based “We Fit” weight control programme in adolescents
Chae, S., Yeo, J., Hwang, J., & Kang, H. S. (2021) · Nursing Open · doi:10.1002/nop2.1125 · Cited by 6 · see citing works
Fat embolism syndrome with neurological involvement: A case report
Ostlie, A., Gilbert, M. M., Lewis, C., Ostlie, D. J., & Hargis-Villanueva, A. E. (2022) · Trauma Case Reports · doi:10.1016/j.tcr.2022.100607 · Cited by 6 · see citing works
Liu, M., Xu, Y., Yang, G., Li, Z., Luo, G., & Yang, S. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/2392652 · Cited by 6 · see citing works
Hua, X., Xu, M., Yang, M., Zhang, Y., Ma, J., Cheng, L., Chu, C., Wu, Z., & Guo, M. (2024) · Food Frontiers · doi:10.1002/fft2.488 · Cited by 5 · see citing works
Spina, A., Amone, F., Zaccaria, V., Insolia, V., Perri, A., Lofaro, D., Puoci, F., & Nobile, V. (2024) · Foods · doi:10.3390/foods13233883 · Cited by 5 · see citing works
- Authors
- Stewart, J., McCallin, T., Martinez, J., Chacko, S., & Yusuf, S.
- Affiliations
- Baylor College of Medicine (US)
- Venue
- Pediatrics in Review
- Publisher
- American Academy of Pediatrics (AAP)
- Published
- 2020-08-01
- Volume
- 41
- Issue
- 8
- Pages
- 393-402
- ISSN
- 0191-9601 (ISSN-L)
- 1526-3347
- OpenAlex
- W4232459612
- Cited by
- 239
- References
- 40
- Citations by year
- 2026: 28 · 2025: 56 · 2024: 67 · 2023: 37 · 2022: 38 · 2021: 12
- FWCI
- 4.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pediatrics in Review (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
- Keywords
- hyperlipidemia, childhood obesity, familial hyperlipidemia, cardiovascular disease, atherosclerosis, cholesterol screening, statin therapy, diabetes mellitus, kidney disease, prognosis, prevention
- MeSH terms
- Adolescent, Child, Combined Modality Therapy, Humans, Hyperlipidemias, Pediatrics, Risk Factors, United States
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