The DOI matches its Crossref record; 10 of the 11 references it cites were found in a registry or an index.
COVID-19 Vaccine Breakthrough Infections Reported to CDC — United States, January 1–April 30, 2021
Open accessAbstract
COVID-19 vaccines are a critical tool for controlling the ongoing global pandemic. The Food and Drug Administration (FDA) has issued Emergency Use Authorizations for three COVID-19 vaccines for use in the United States.* In large, randomized-controlled trials, each vaccine was found to be safe and efficacious in preventing symptomatic, laboratory-confirmed COVID-19 (1-3). Despite the high level of vaccine efficacy, a small percentage of fully vaccinated persons (i.e. received all recommended doses of an FDA-authorized COVID-19 vaccine) will develop symptomatic or asymptomatic infections with SARS-CoV-2, the virus that causes COVID-19 (2-8).
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“In April 2021, U.S. Centers for Disease Control and Prevention (CDC) issued a notice that breakthrough infections of COVID-19 in vaccinated individuals would no longer be recorded unless the cases were hospitalized [36].”
From Relative risk reduction: Misinformative measure in clinical trials and COVID-19 vaccine efficacy (2022) · cites this paper as [36]
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Cites
Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Polack, F. P., Thomas, S. J., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Perez, J. L., Pérez Marc, G., Moreira, E. D., Zerbini, C., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2034577 · Cited by 14,592
Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
Baden, L. R., El Sahly, H. M., Essink, B., Kotloff, K., Frey, S., Novak, R., Diemert, D., Spector, S. A., Rouphael, N., Creech, C. B., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2035389 · Cited by 10,119
Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19
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Rapid, Sensitive, Full-Genome Sequencing of Severe Acute Respiratory Syndrome Coronavirus 2
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Swift, M. D., Breeher, L. E., Tande, A. J., Tommaso, C. P., Hainy, C. M., Chu, H., Murad, M. H., Berbari, E. F., & Virk, A. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciab361 · Cited by 98
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Metadata
- Authors
- CDC COVID-19 Vaccine Breakthrough Case Investigations Team, CDC COVID-19 Vaccine Breakthrough Case Investigations Team, Birhane, M., Bressler, S., Chang, G., Clark, T., Dorough, L., Fischer, M., Watkins, L. F., Goldstein, J. M., Kugeler, K., Langley, G., Lecy, K., Martin, S., Medalla, F., Mitruka, K., Nolen, L., Sadigh, K., Spratling, R., Thompson, G., & Trujillo, A.
- Corresponding author
- Fischer, Marc
- ORCID
- Venue
- MMWR. Morbidity and Mortality Weekly Report
- Published
- 2021-05-28
- Volume
- 70
- Issue
- 21
- Pages
- 792-793
- ISSN
- 0149-2195 (ISSN-L)
- 1545-861X
- PMC
- PMC8158893
- OpenAlex
- W3165605711
- Cited by
- 421
- References
- 11
- Citations by year
- 2026: 10 · 2025: 23 · 2024: 31 · 2023: 68 · 2022: 173 · 2021: 115
- FWCI
- 30.64
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- MMWR Morbidity and Mortality Weekly Report (publishedVersion)
- PubMed Central (publishedVersion, public-domain)
- PubMed (publishedVersion)
- Funders
- Centers for Disease Control and Prevention
- Topics
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Physical Sciences › Mathematics › Modeling and Simulation › COVID-19 epidemiological studies
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Keywords
- SARS-CoV-2, COVID-19 vaccines, vaccine efficacy, asymptomatic infection, emergency use authorization, vaccine safety, United States
- MeSH terms
- COVID-19, COVID-19 Vaccines, Adult, Aged, Aged, 80 and over, Centers for Disease Control and Prevention, U.S., Female, Humans, Male, Middle Aged, United States, Treatment Failure, Disease Notification
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