Randomized Controlled Trials in Implant Dentistry: Assessment of the Last 20 Years of Contribution and Research Network Analysis
Abstract
The aim of this study was to evaluate the characteristics of randomized controlled trials (RCTs) regarding implant-supported single tooth or fixed partial dentures. We performed searches (PubMed/MEDLINE and Web of Science) to identify all RCTs published from 1996 to 2016 and assessed publication details, study characteristics, international collaboration networks, and characteristics related to the implant-supported treatment. Two reviewers independently screened the titles/abstracts and selected full texts. A total of 122 RCTs were included, and most of the authors were from Europe (72%). Most trials did not report a trial registering number (89.9%) or sample size calculation (58.2%). The use of the CONSORT Statement increased over the past 9 years. Trials were mostly conducted at universities (54.9%), and only 13.1% compared 2 or more implant brands. Loading protocol was the most prevalent main comparison among the included studies, and most of the RCTs did not clearly report whether they excluded patients with known risk factors. The studies reviewed here presented different methodological and publication characteristics, and many did not show aspects aligned with current research practices.
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Reviews have found that adherence to CONSORT guidelines remains incomplete across various domains of dentistry.
“However, reviews have found that adherence to the guidelines remains incomplete across various domains of dentistry (Meyer et al. 2023; Sarkis-Onofre et al. 2019).”
From Adherence to the CONSORT statement of randomized clinical trials on dentin hypersensitivity treatment using mouthwashes (2025) · cites this paper as Sarkis-Onofre et al. 2019
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“However, reviews have found that adherence to the guidelines remains incomplete across various domains of dentistry (Meyer et al. 2023; Sarkis-Onofre et al. 2019).”
- Authors
- Sarkis-Onofre, R., Marchini, L., Spazzin, A. O., & Santos, M. B. F. D.
- Affiliations
- Graduate Program in Dentistry, IMED, Passo Fundo, RS, Brazil.
- University of Iowa (US)
- Atitus Educação (BR)
- Universidade Federal de Pelotas (BR)
- Venue
- Journal of Oral Implantology
- Published
- 2019-08
- Volume
- 45
- Issue
- 4
- Pages
- 327-333
- ISSN
- 0160-6972 (ISSN-L)
- 1548-1336
- OpenAlex
- W2950622201
- Cited by
- 7
- References
- 31
- Citations by year
- 2025: 1 · 2022: 2 · 2021: 2 · 2020: 2
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Oral Implantology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Dentistry › Oral Surgery › Dental Implant Techniques and Outcomes
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › scientometrics and bibliometrics research
- Keywords
- implant-supported fixed partial dentures, randomized controlled trials, research collaboration networks, publication characteristics, CONSORT statement, clinical trial registration, sample size determination, loading protocols, methodological quality
- MeSH terms
- Dental Implantation, Endosseous, Dentistry, Humans, Dental Implants, Randomized Controlled Trials as Topic
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