Cited by 16Hepatitis C virus researchHelicobacter pylori-related gastroenterology studiesSubstance Abuse Treatment and Outcomes

Interferon-based hepatitis C treatment in patients with pre-existing severe mental illness and substance use disorders

Freedman, Kenneth, Nathanson, Jay·2009·Expert Review of Anti-infective Therapy

Abstract

Hepatitis C infection in patients with mental illness and drug addiction is highly prevalent and infrequently treated. Over the past 5 years, a wealth of studies specifically focused on these groups have demonstrated comparable rates of sustained virological response, compliance and adverse events. Optimization of psychotropic and opioid-replacement therapy with integrated psychiatric/addiction treatment prior to and during IFN-alpha initiation produces optimal results. Experience in treating these populations demonstrates clinical outcomes comparable with those without these comorbidities. Patients with mental illness and drug addiction should have routine screening and treatment for HCV infection to prevent associated morbidity and mortality.

Integrity signals

Registry

Crossref · 10.1586/eri.09.1

Cites

44 of 44 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Freedman, K., & Nathanson, J.
Affiliations
  • Tufts University (US)
  • University of Massachusetts Chan Medical School (US)
Venue
Expert Review of Anti-infective Therapy
Published
2009-04
Volume
7
Issue
3
Pages
363-376
ISSN
  • 1478-7210 (ISSN-L)
  • 1744-8336
OpenAlex
W2114635652
Cited by
16
References
43
Citations by year
2022: 1 · 2013: 1 · 2012: 4
FWCI
0.56
Type
journal article
Language
en
Open access
closed
Locations
  • Expert Review of Anti-infective Therapy (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institutes of Health
Topics
  • Health Sciences › Medicine › Hepatology › Hepatitis C virus research
  • Health Sciences › Medicine › Surgery › Helicobacter pylori-related gastroenterology studies
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
hepatitis C, interferon-alpha, severe mental illness, substance use disorders, drug addiction, psychiatric comorbidity, sustained virological response, medication adherence, adverse events, psychotropic drugs, opioid substitution therapy, HCV screening, HCV treatment outcomes
MeSH terms
Antiviral Agents, Mental Disorders, Drug Therapy, Combination, Hepatitis C, Humans, Interferons, Polyethylene Glycols, Ribavirin, Hepacivirus, Treatment Outcome, Substance-Related Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review